ProFound Therapeutics

Senior Scientist, Computational Genomics 

PhD in biology/statistics/genomics with 5+ years post-PhD; deep genomics data analysis (Illumina); end-to-end NGS; multi-modal data; probabilistic modeling; startup environment.

Senior Scientist, Computational Protein Design

PhD in structural biology, biophysics, protein design, or related field; 2+ years in structure-guided protein design; expertise with RFdiffusion, proteinMPNN, AF2, Boltz2, BoltzGen, Rosetta or similar; strong biophysics knowledge; ability to progress designs to experiments; excellent communication.

(Senior) Scientist, ML/AI Antibody Design

Scientist

Ph.D. in a related field with 2+ years of industry research; expertise in computational protein design, modeling, and ML tools; experience with antibody design; strong communication and collaboration skills.

Senior Counsel, Legal

Senior Counsel

J.D. and US bar; 8+ years in complex life sciences transactions; top-tier firm experience; pharma collaborations, licensing, and M&A experience a plus.

Senior Software Engineer, Front End

Senior Front-End Software Engineer

Senior front-end engineer with 6+ years of experience, strong React/TypeScript, and ability to lead UI development for AI-assisted platforms.

Senior / Principal Scientist, Structural Biology

Structural Biologist

PhD or MS in structural biology or related field with 3+ years of industry drug discovery experience; expertise in X-ray crystallography and cryo-EM; CRO management; collaboration, communication, and problem-solving skills; knowledge of biophysical methods and protein biochemistry.

Vice President, Data Platform (Pioneering Intelligence)

Vice President, Data Platform

Experience designing scalable data platforms for ML with sensitive data; strong product mindset; leadership of software/infrastructure teams; governance and stakeholder communication.

Principal Backend Developer

Backend Engineer

5+ years frontend development; Bachelor's in CS/Software Eng; React, Next.js, TypeScript, HTML/CSS; REST/GraphQL; performance optimization; Storybook; startup experience.

Head of Clinical Development

MD or MD, PhD with 8+ years in biopharma, small molecule development; leadership experience; regulatory submissions; partnerships; immunology/inflammation expertise.

Director of Sales

8+ years in commercial or sales leadership in life sciences or related tech; proven multi-million sales success; cross-functional leadership; strong negotiation, forecasting, and account planning; excellent exec-level communication.

Senior Accountant

CPA licensed; bachelor’s in Accounting/Finance; 4+ years accounting; US GAAP; ERP experience; advanced Excel.

Director, Business Development & Partnership -South Korea

Director, Business Development & Partnership

8-10 years in business development/partnerships within life sciences; Korea market knowledge; fluent in Korean and English; MBA/PhD preferred.

Principal Scientist, Machine Learning

Principal Scientist

PhD or Master’s in ML/comp-sci with 5+ years in academic or biotech settings; proven leadership and multidisciplinary AI/ML project leadership.

SVP AI & Digital Platform

Senior Vice President AI & Digital Platform

15+ years leadership in AI, data platforms, or digital tech; proven ability to scale AI-native platforms and teams.

Senior Director, Communications 

Senior communications leader with pharma/biotech PR experience; strategic branding; media relations; team leadership.

Open Call

Experience in AI/Software, automation, physics, or hardware for biology; interdisciplinary collaboration.

Contract - Senior Research Associate, Protein Sciences

Senior Research Associate

Bachelor's or master's degree in relevant field with 3+ years (MS) or 5+ years (BS) of industry experience in biotechnology or pharmaceutical companies.

Title	Location	Date
Senior Scientist, Computational Genomics Full Time · $146K-$209K · 5+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Mar 2, 2026
Senior Scientist, Computational Protein Design Full Time · $146K-$209K · 2+ YOE Boston, Massachusetts, United States · Onsite	Boston, Massachusetts, United States Onsite	Feb 26, 2026
(Senior) Scientist, ML/AI Antibody Design Full Time · $115K-$259K · 2+ YOE Boston, Massachusetts, United States · Onsite	Boston, Massachusetts, United States Onsite	Feb 10, 2026
Senior Counsel, Legal Full Time · $204K-$346K · 8+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Feb 3, 2026
Senior Software Engineer, Front End Full Time · $108K-$176K · 6+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Feb 2, 2026
Senior / Principal Scientist, Structural Biology Full Time · $126K-$215K · 3+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Jan 28, 2026
Vice President, Data Platform (Pioneering Intelligence) Full Time · $275K-$365K Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Dec 23, 2025
Principal Backend Developer Full Time · $152K-$209K · 5+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Dec 12, 2025
Head of Clinical Development Full Time · $360K-$415K · 8+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Dec 9, 2025
Director of Sales Full Time · $100K-$140K · 8+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Nov 24, 2025
Senior Accountant Full Time · $88K-$121K · 4+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Nov 6, 2025
Director, Business Development & Partnership -South Korea Full Time · 8+ YOE Korea · Onsite	Korea Onsite	Oct 16, 2025
Principal Scientist, Machine Learning Full Time · $208K-$286K · 5+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Oct 14, 2025
SVP AI & Digital Platform Full Time · 15+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Aug 26, 2025
Senior Director, Communications Full Time · $204K-$281K Cambridge, Massachusetts, United States · Hybrid	Cambridge, Massachusetts, United States Hybrid	Jul 30, 2025
Open Call Full Time Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Feb 11, 2025
Contract - Senior Research Associate, Protein Sciences Contract · 5+ YOE Cambridge, Massachusetts, United States · Onsite	Cambridge, Massachusetts, United States Onsite	Jan 17, 2025

Activities	Identifying novel human proteinsDeveloping first-in-class protein medicinesIdentifying therapeutic drug targetsMapping the human proteomeComputational protein characterization
Headquarters	US
Industries	BiotechnologyLife Sciences
Name	ProFound Therapeutics
Employees	50
Type	Private
Parent Company	Flagship Pioneering
Tagline	Discovering novel proteins to develop first-in-class medicines.
Founded	2,020
Website	profoundtx.com
Latest Funding Round	Series A
Latest Funding Year	2,022
Latest Funding Amount	75,000,000
Latest Investors	Flagship Pioneering

ProFound Therapeutics

About ProFound Therapeutics