Posted 17h ago

Principal Business Systems Analyst

@ Glaukos
Aliso Viejo, California, United States
$143k-$179k/yrOnsiteFull Time
Responsibilities:leading design, overseeing integrations, ensuring compliance
Requirements Summary:12+ years SAP/enterprise systems experience with S/4HANA supply chain expertise; Bachelor's in IS/Supply Chain/Engineering; experience in regulated (GxP) environments; knowledge of SAP modules, PLM/MES/QMS; strong analytical and communication skills.
Technical Tools Mentioned:SAP S/4HANA, MM, PP, SD, QM, WM, EWM, PLM, MES, QMS
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Job Description

GLAUKOS - PRINCIPAL BUSINESS SYSTEMS ANALYST  

How will you make an impact?

Serve as a strategic and technical leader driving SAP S/4HANA supply chain solutions in a regulated GxP environment. Enable scalable, compliant, and audit‑ready systems that support product lifecycle and end‑to‑end supply chain operations, while influencing enterprise strategy and cross‑functional initiatives.

What will you do?

  • Lead design and delivery of SAP S/4HANA solutions across supply chain modules (MM, PP, SD, QM, WM/EWM)
  • Partner across Supply Chain, Quality, Engineering, Manufacturing, and IT to align business needs with system capabilities
  • Drive end‑to‑end process optimization from product lifecycle through procurement, manufacturing, and distribution
  • Oversee SAP integrations with PLM and other enterprise systems to ensure data integrity and traceability
  • Ensure compliance with GxP requirements (FDA, EU, ISO) through validated, audit‑ready solutions
  • Lead testing, validation, data migration, and deployment activities (UAT, hypercare)
  • Mentor team members and establish best practices, governance, and standards
  • Act as a trusted advisor to stakeholders, translating complex requirements into scalable solutions

How will you get here?

  • Bachelor’s degree in Information Systems, Supply Chain, Engineering, or related field (advanced degree or certifications preferred)
  • 12+ years of SAP or enterprise systems experience, with strong S/4HANA supply chain expertise
  • Experience within regulated environments (Life Sciences, Medical Devices, or Pharmaceuticals)
  • Deep knowledge of SAP supply chain modules, Quality processes, and system integrations (PLM, MES, QMS)
  • Proven ability to lead complex, cross‑functional implementations and influence stakeholders
  • Strong analytical, communication, and problem‑solving skills with a high degree of independence

#GKOSUS

Company

Generous. Innovative. Leadership-driven. Family-oriented. Socially responsible. 

 

Founded in 1998, Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company focused on developing and commercializing novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases.

 

Our mission at Glaukos is to truly transform vision by pioneering novel, dropless therapies that can meaningfully advance the standard of care and improve the lives of patients suffering from chronic, sight-threatening eye diseases. 

 

Innovation is at the core of everything we do, and we are resolute in our commitment to challenge conventional thinking with new treatment alternatives that are supported by real science, robust clinical evidence, and an unrelenting focus on patients. 

 

Our constant pursuit of game-changing technologies that disrupt legacy treatment paradigms is encapsulated in the Glaukos mantra “We’ll Go First,” which articulates our willingness to take chances, our determination to forge new ground, and our commitment to continuous improvement in all that we do.   

 

Our company completed an initial public offering in June of 2015, and our shares are traded on the New York Stock Exchange under the ticker symbol “GKOS”. Our global headquarters is in Aliso Viejo, California with additional locations in San Clemente, California, and Burlington, Massachusetts.

 

Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law. 


All offers of employment are contingent upon the successful completion of a background check, including successfully passing a drug screen, based on the position and local regulations.