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Full Stack Python Developer Jobs in United States
2,000+ full stack python developer jobs from 1,000+ companies hiring in United States.
3w
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Member of Technical Staff (Frontend)
New York City, New York, United States
$170k-$270k/yr OnsiteFull Time
Anterior: AI platform for automating healthcare administrative workflows.
Frontend-focused engineer with cross-stack collaboration, React/HTMX expertise, strong UI/UX, and experience designing scalable backend services.
React, HTMX, TypeScript, Python, Go, AWS, Nix, CDKTF, Backend services, APIs, SQL
2mo
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Data Scientist, Evals
London or New York City or Belgrade
$210k-$385k/yr OnsiteFull Time
4+ YOEPhD or MS in a technical field or equivalent experience; 4+ years data science or machine learning; strong Python/SQL; cloud data stack (AWS, Databricks); AI-assisted development tools.
Python, SQL, AWS, Databricks, LLM tooling
3w
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Principal Machine Learning Scientist, Drug Discovery Analytics
Redwood City, California, United States
$273k-$321k/yr OnsiteFull Time
8+ YOEPhD in ML, computational chemistry, computational biology, or CS; 8+ years applying ML to scientific problems; experience with chemical/biological data; Python ML stack; strong communication.
PyTorch, TensorFlow, scikit-learn, NumPy, Pandas
2mo
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Senior Manager, Software Engineering
Boston, Massachusetts, United States
$170k-$220k/yr OnsiteFull Time
10+ YOE5+ Mgmt10+ years in technology; 5+ years in engineering leadership; experience embedding Generative AI; proven transformational leader; strong communication; client-focused; experience with modern stacks and agile practices.
Python, Flask, Azure, React, GraphQL, PHP, Ansible, Jenkins, Airflow
2w
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Principal Engineering Manager
United States
$160k-$425k/yr RemoteFull Time
11+ YOE5+ Mgmt11+ years in software engineering or related field; 5+ years people management; strong leadership and architectural skills; experience with distributed teams; proficiency in modern web stacks and AI tools.
C, C++, C#, Java, JavaScript, Go, Ruby, Rust, Python, Ruby on Rails, React, TypeScript, GraphQL
1w
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Senior Technologist
Raleigh or Richardson
HybridFull Time
5+ YOEStrong Java microservices, Spring Boot, cloud, AI tools, and full-stack experience; AWS, Docker/Kubernetes; OpenAI/LangChain; multi-language development; willing to relocate and eligible to work in the US.
Java, Spring Boot, Microservices, Docker, Kubernetes, Kafka, RabbitMQ, AWS, OpenAI, LangChain, Python, Angular, MySQL
4d
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Distillation Lead
San Francisco or Toronto or Pittsburgh or United States
$195k-$286k/yr HybridFull Time
Lead distillation and model compression for Waabi's AI stack; hands-on PyTorch/JAX; cross-functional leadership.
Python, PyTorch, JAX
2mo
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Senior Associate - Development Lead - Digital Experience Platform (New York, NY, US)
New York or United States
$124k-$177k/yr HybridFull Time
7+ YOEExperience in modern front-end architectures, AI-enabled platforms, AWS, AEM, design systems, and AI/ML integration; strong full-stack capabilities.
React, Angular, Flutter, HTML/CSS, AWS, Adobe Experience Manager (AEM), LangChain, CrewAI, TensorFlow, PyTorch, Python, MLOps
1mo
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Senior Data Scientist
Pittsburgh, Pennsylvania, United States
HybridFull Time
4+ YOEMaster's in data science, information systems, engineering or related field; 4 years post-baccalaureate experience; expertise in Spark/Hadoop, cloud platforms, Power Platform, GIS, ML, CV, NLP, databases, full-stack development, and data visualization.
Apache Spark, Hadoop, AWS, Azure, Google Cloud, Microsoft Power Platform, Power BI, Power Apps, Power Automate, ArcGIS, QGIS, Google Earth Engine, OpenCV, TensorFlow, PyTorch, Scikit-learn, SpaCy, Hugging Face, NLTK, SQL, NoSQL, MongoDB, Cassandra, Neo4j, TigerGraph, React, Node.js, Vue, Next.js, Python, R, Java, C++, Tableau, Matplotlib
1mo
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Architect: Risk, Marketing and Admin Systems
Chicago, Illinois, United States
$150k-$198k/yr OnsiteFull Time
8+ YOESenior technical leader with 8+ years in software development, data integration, and enterprise applications; strong Microsoft stack, cloud, DevOps, and architecture leadership.
.NET, ASP.NET, C#, MVVM, MVC, Web APIs, SQL Server, SSIS, Azure Data Factory, Logic Apps, Service Bus, Azure SQL Database, Azure DevOps, GitHub, Docker, Kubernetes, PowerShell, JavaScript, TypeScript, Python, Informatica, BizTalk, MuleSoft, Harvey, Claude, GitHub Copilot, ChatGPT, K2, Power Automate, Logic Apps
3w
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Senior COTS Integrator
Annapolis Junction, Maryland, United States
$185k-$238k/yr OnsiteFull Time
12+ YOETS/SCI with Polygraph; 12+ years software development/engineering experience; Bachelor's in Computer Science or related field; strong Elastic Stack, web services, scripting, and Linux experience.
Elastic Stack, Jenkins, REST APIs, OpenTelemetry, Python, Vega, NiFi, AWS, HTML, JavaScript, UNIX, Windows, Kibana, Logstash, Elasticsearch, Ansible, Terraform, Selenium, SiteScope, OMi, OTEL, OTLP
4d
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eBusiness & Integration Architect
Wayne, Pennsylvania, United States
HybridFull Time
5+ YOEBachelor's degree; 5-8+ years cross-system interface development and EDI; SAP tech stack experience; API/EDI, sFTP; cloud EDI platforms; SDLC; strong communication.
SAP BTP Integration Suite, SAP PO, SAP BTP CPI, sFTP, Elemica, Seeburger, Boomi, trueCommerce, goAnywhere, ANSI X12, EDIFACT, cXML, XML, xCBL, iDoc, BPMN, API Management, JavaScript, Python, Groovy, AI integration
HiringCafe market data
Full Stack Python Developer Jobs market signals in United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
2,000+
Hiring companies
1,000+
Fresh sample
62% new in 30d
Salary visibility
69% show pay
Companies appearing in this market
InfosysAnteriorGHDGitHubMayer BrownNew York LifePartners CapitalPerplexity
Work location mix in visible results
Onsite: 7Hybrid: 5Remote: 1