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Python Developer Jobs in Guilford, PA, US
51 python developer jobs from 37 companies hiring in Guilford, PA, US.
2w
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Fullstack Python Developer
Center Square, Pennsylvania, United States
RemoteMultiple Commitments Available
Proficient in Python (Django/FastAPI), React/Next.js, SQL; Agile/Scrum; Azure; automation focus; able to manage multiple projects.
React, Next.js, Python, Django, FastAPI, SQL, REST API, Azure, MSTest, Azure Application Insights, Serilog
2w
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Senior Software Developer
Richmond or Baltimore or Nashville or Mechanicsburg or Raleigh
$105k-$145k/yr HybridFull Time
5+ YOESenior software developer with 5+ years of experience in full-stack design and geospatial applications.
SQL, C#, Java, Python, HTML, CSS, JavaScript, ASP.Net Core, Angular, React, Vue.js, Esri software
1mo
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Embedded Software Test Engineer I
New Freedom, Pennsylvania, United States
$75k-$103k/yr OnsiteFull Time
2+ YOE2+ years in software development/testing; experience in embedded systems; C/C++, Python; hardware test tools; US citizen or permanent resident.
C, C++, Python, oscilloscopes, logic analyzers, JTAG
4d
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US E - GPS Consulting Services - ServiceNow Developer *SS* - HC/HRST - USDC - Profile
Gilbert or Lake Mary or Mechanicsburg
HybridFull Time
4+ YOE4+ years of technical web development experience; HTML, CSS, JavaScript, and/or Python; Bachelor's degree; hybrid work with US Delivery Center locations; US work authorization; travel up to 10%; relocation within 12 weeks if needed.
HTML, CSS, JavaScript, Python
2mo
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Scientific Software Engineer (Full Stack)
Frederick, Maryland, United States
$115k-$125k/yr HybridFull Time
Bachelor’s or master’s in computer science or software engineering; full-stack data-intensive apps; Python backend (FastAPI/Litestar); React/TypeScript frontend; WebGL visualizations; containerized cloud deployments.
Python, FastAPI, Litestar, React, TypeScript, Deck.gl, PixiJS, Plotly, gRPC, GraphQL, Kubernetes, Docker, Redis, WebSockets, SSE
2mo
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Senior Full-Stack Engineer
Culver City or Linthicum or Allen or Woodcliff Lake or Chicago or Orlando or Baton Rouge or Waltham or Phoenix or Harrisburg or West Valley City or Austin or Alpharetta or San Diego or Indianapolis or Lexington or Parma or Little Rock or Asheville or Birmingham or Chantilly or Washington or Brentwood or Plantation or Fort Collins or San Mateo or Schaumburg or Brooklyn
$140k-$180k/yr OnsiteFull Time
7+ YOE7+ years in software development; Bachelor's degree in CS/Engineering; backend (Node.js) and frontend (React) experience; API integrations; cloud and database experience.
Node.js, HapiJS, Python, JavaScript, React, SQL, Serverless, Lambda, CloudFormation, Elastic Beanstalk, EC2, VPC, DynamoDB, RDS, G Suite, Microsoft Graph, Okta, OneLogin, Slack, Linux, Docker, Datadog, CloudWatch, MQTT, log/data pipelines
1w
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Software Engineer Security & Automation II (Full Time) – United States
San Jose or Austin or Milpitas or Alpharetta or Maynard or Fulton or New York or Boston or Knoxville or Dallas or Atlanta or Hillsboro
HybridFull Time
0+ YOEPython or scripting, security principles, DevSecOps, cloud security, automation, CI/CD, security tools; degree/certifications with relevant experience.
Python, Bash, Jenkins, GitHub Actions, Docker, Kubernetes, pytest
1mo
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Actuarial Developer
Frederick, Maryland, United States
$108k-$148k/yr RemoteFull Time
5+ YOE5+ years actuarial experience in life insurance/valuation; data/tech skills; Python/R/Spark; SQL/NoSQL; cloud (AWS/Azure); BS/BA in related field; SOA associate certification.
Azure, Databricks, Git, SQL, NoSQL, Python, R, Spark
2w
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Software Engineer, I - Java
Fort Washington, Pennsylvania, United States
$90k-$100k/yr RemoteFull Time
2+ YOETwo+ years in Java 17+/Spring Boot; experience with React; healthcare IT standards; AI tools Claude; remote work; bachelor's degree or equivalent.
Java, Spring Boot, React, Delphi, Python, MySQL, MongoDB, Claude, AWS, Git, Subversion, REST, FHIR, HL7, CCDA, X12, Networking
3w
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Sr. Innovation Software Engineer
Minnetonka or Austin or Chicago or Easton or Dallas or Detroit or Hagerstown or Atlanta or Houston or Akron or Birmingham or Charlotte or Indianapolis or Pittsburgh or Cincinnati or Cleveland
$77k-$154k/yr OnsiteFull Time
8+ YOESenior software engineer with full-stack, AI-enabled solution delivery; 8-12 years of experience.
Java, Python, TypeScript/JavaScript, Vertex AI, Google Cloud
1mo
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Principal Engineer - Controls
Hagerstown, Maryland, United States
$92k-$148k/yr OnsiteFull Time
5+ YOEBachelor's degree in mechanical/electrical engineering with 5+ years of related experience; strong vehicle controls experience; CAN bus; MATLAB/Simulink; AMEsim; dSPACE; Autosar; C/C++; Python.
MATLAB/Simulink, AMEsim, dSPACE, Vector tools, Autosar, C/C++, Python, ADAMS
2w
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Business Intelligence Developer
Harrisburg, Pennsylvania, United States
OnsiteFull Time
2+ YOE2-5 years BI development experience; SQL and Power BI proficiency; Azure data services; ETL/ELT; data modeling; strong communication.
Power BI, SQL, SQL Server, Azure Data Factory, Synapse Analytics, Databricks, SQL Server Integration Services, Git, Jira, Python, R, Power Query, DAX, Excel, SharePoint, Outlook
3d
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Lead Analytics Engineer
Wyomissing or Harrisburg
OnsiteFull Time
3+ YOEThree+ years of related experience; strong Snowflake, SQL, Python; experience with data governance and cloud data architectures.
Snowflake, SQL, Azure, Python, dbt Core, dbt Cloud
3d
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Lead Analytics Engineer
Wyomissing or Harrisburg
OnsiteFull Time
3+ YOESnowflake, SQL, Python, Azure; data governance; 3+ years of related experience; Bachelor’s degree in a relevant field.
Snowflake, SQL, Azure, Python, dbt Core/Cloud
2mo
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Applied AI Developer
York, Pennsylvania, United States
HybridFull Time
3+ YOEProficiency in ML frameworks (TensorFlow, PyTorch, Scikit-learn, or Keras); computer vision with OpenCV; DL-based vision models; ML/AI methods; Python or C++; data analysis with Pandas, NumPy, SQL; strong problem solving; Azure DevOps; MLOps; Docker; REST APIs; good communication.
TensorFlow, PyTorch, Scikit-learn, Keras, OpenCV, Azure DevOps, Docker, Python, C++, Pandas, NumPy, SQL
2mo
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Mission Autonomy Engineer
Clarksburg, Maryland, United States
$180k-$250k/yr OnsiteFull Time
8+ YOEMaster’s in CS/Engineering; 8+ years AI/autonomy experience; agentic AI platforms; languages: C++, Python, Rust; Linux; project leadership; collaborative.
C++, Python, Rust, Linux
1w
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Palantir AIP & Foundry Lead Engineer
Camp Hill, Pennsylvania, United States
OnsiteFull Time
10+ YOEBachelor's degree in STEM; 3+ years with Palantir Foundry/AIP; proficiency in Python, SQL, PySpark, TypeScript; strong data and cloud/ frontend tooling experience; healthcare experience preferred.
Python, SQL, PySpark, Typescript
6d
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Forward Deployment Engineer (York, PA)
York or Philadelphia or Baltimore
OnsiteFull Time
5+ YOE5+ years in healthcare integration; HL7 v2, FHIR, X12; Python and integration engines; REST, JSON, SQL; strong communication; ownership and reliability.
Python, HL7 v2, FHIR, X12, REST APIs, SQL, Mirth, Rhapsody, InterSystems IRIS, Redox, Docker, CI/CD
1w
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Palantir AIP & Foundry Lead Engineer
Camp Hill, Pennsylvania, United States
RemoteFull Time
10+ YOE10 years of experience with Palantir Foundry/AIP, Python/SQL/PySpark/Typescript; data pipelines; healthcare domain experience preferred.
Python, SQL, PySpark, Typescript
3mo
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Project Engineer 1 - New College Grad 2025 - 2026 (E&C - Frederick, MD)
Frederick, Maryland, United States
$76k-$113k/yr OnsiteFull Time
0+ YOEBachelor’s degree in Electrical, Mechanical, Systems, or Industrial Engineering; 0+ years preferred; CAD/SolidWorks/Revit/Python/SCADA/MATLAB/VHDL experience.
CAD, SolidWorks, Revit, Python, SCADA, MATLAB, VHDL
3w
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Data Engineer
Mechanicsburg or Yorktown
OnsiteFull Time
5+ YOESecret clearance required; 5+ years data engineering; AWS GovCloud; SQL/PostgreSQL; ETL; data warehousing; BA/BS; cloud and security certifications.
SQL, PostgreSQL, Python, AWS, AWS GovCloud, ETL, Redshift, Data modeling, Oracle Database
1w
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Cybersecurity Engineer
Philadelphia or Battle Creek or Columbus or Dayton or Ft. Belvoir or New Cumberland or Ogden or Richmond
RemoteFull Time
7+ YOE7+ years cybersecurity experience; DoD compliance; RMF artifacts; vulnerability management; scripting; DoD inspections familiarity.
MECM, Tanium, Intune, ACAS, Nessus, Qualys, Forescout, Eyeinspect, PowerShell, Python
3w
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Network Engineer II
Hagerstown, Maryland, United States
$75k-$103k/yr OnsiteFull Time
2+ YOEActive US Top Secret/SCI clearance; Bachelor’s in IT or 6+ years experience; 2+ years in related field; Windows/Linux admin; Cisco networking; security focus; able to mentor others; eligible for duty with DoD.
Windows, Linux, Cisco, DNS, DHCP, VPN, PowerShell, Python, VMware, Hyper-V, Active Directory, Windows Server, Windows 11
2mo
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Modeling and Simulation HPC Back End Software Developer
Frederick, Maryland, United States
$94k-$198k/yr OnsiteFull Time
5+ YOETS/SCI with polygraph; BS in Computer Science, Modeling and Simulations or related field; 5+ years’ experience; Python, C Shell, Slurm; Unix/HPC experience; strong communication; ability to brief senior leaders.
Python, C Shell, Slurm, UNIX, High-Performance Computing
1mo
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Data Engineer – NAVSUP OIS - Onsite
Mechanicsburg or Yorktown
$130k-$155k/yr OnsiteFull Time
10+ YOE10+ years of data engineering experience; TS clearance; US citizenship; AWS GovCloud; ETL; SQL/NoSQL; data warehousing; cloud data platforms.
AWS GovCloud, AWS RDS, PostgreSQL, MySQL, Oracle, Pentaho, Apache Hadoop, Apache Spark, Kafka, RedShift, MicroStrategy, Erwin Data Modeler, Python, Java, Scala, Go
1mo
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Data Engineer – NAVSUP OIS - Onsite
Mechanicsburg or Yorktown
$130k-$155k/yr OnsiteFull Time
General Dynamics Information TechnologyNYSE: GD: Provides mission-critical IT services to government and defense organizations.
10+ YOE10+ years of related experience; Top Secret clearance; US citizenship; AWS GovCloud; SQL/ETL; data warehousing; strong collaboration skills.
AWS GovCloud, RDS, PostgreSQL, MySQL, Oracle, SQL, Python, Java, Scala, Go, Spark, Kafka, Hadoop, RedShift, Liquibase, GitLab, CI/CD, ETL, Pentaho, Erwin Data Modeler
1d
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Senior Cloud Computing Engineer
Frederick, Maryland, United States
RemoteFull Time
8+ YOE8+ years AWS cloud engineering with CI/CD, security, IAM, IaC; strong AWS services knowledge; US citizenship required for opportunity.
AWS, CloudFormation, Terraform, CDK, Jenkins, Git, Python, Bash, PowerShell, Node.js, Prometheus, Grafana, New Relic
1mo
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Staff Mission Assurance Engineer
Sykesville, Maryland, United States
$169k-$254k/yr OnsiteFull Time
12+ YOEBachelor’s in a STEM field with 12+ years quality experience or Master’s with 10+ years; requires US citizenship and ability to obtain Secret DoD clearance.
Java, C++, C#, Ada, VHDL, Python, MATLAB, JIRA, Version control
1mo
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AI Research Computing Infrastructure Engineer
Frederick, Maryland, United States
$124k-$207k/yr OnsiteFull Time
8+ YOEBachelor’s degree or 4 years experience; 8+ years related experience; Linux systems engineering; container orchestration; scripting; IaC tooling; performance tuning; security clearance ability.
Kubernetes, Nomad, Run:AI, Python, Bash, Go, Terraform, Ansible, Packer, Pytorch, Ray, Airflow, Dagster, Kubeflow, Prefect, Dagster, Kubeflow, MLFlow
3w
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Artificial Intelligence/Machine Learning (AI/ML) Engineer
Annapolis Junction, Maryland, United States
OnsiteFull Time
5+ YOEFive years of applied ML experience; Master's or PhD in AI/ML related field (or 5 extra years with a Bachelor's); proficient in PyTorch/TensorFlow; strong data and model governance, deployment, and evaluation skills.
PyTorch, TensorFlow, Python, Java, R
1mo
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Internship – Software Automation
Saxonburg, Pennsylvania, United States
$25/hr OnsiteFull Time
Internship in software automation; CS/Engineering/Math major; programming in C#, .NET, Python, JavaScript, LabView, Unity; SQL/database a plus; strong analytics.
C#, NET, Python, JavaScript, LabView, Unity, SQL
1mo
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Genomics Computational Systems Biologist
Frederick, Maryland, United States
$140k-$160k/yr OnsiteFull Time
5+ YOEMaster's degree in biomedical science, bioinformatics, math, or computer science; 5+ years experience; HPC, Linux, scripting; NGS data analysis; Python/Perl/Shell/R/C++/Java; U.S. citizen; Tier 1 background check; travel.
HPC, Linux, Python, Perl, Shell, R, C++, Java, Next Generation Sequencing, Oxford Nanopore, Illumina, Pipeline automation, Bioinformatics tools
2mo
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Data Scientist
Alexandria, Virginia, United States
$78k-$176k/yr HybridFull Time
4+ YOE4+ years data science experience; development of algorithms using Python/R; SQL; distributed computing; TS/SCI clearance; Bachelor's degree.
Python, R, pandas, NumPy, scikit-learn, Tidyverse, SQL, Spark, DASK, Databricks
2w
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Sr. Research Associate, Mass Spectrometry (#1901)
Frederick, Maryland, United States
$65k-$107k/yr OnsiteFull Time
6+ YOE6+ years with BS or 4+ with MS; MS instruments (LC-MS/MS, MALDI-TOF); proteomics/metabolomics experience; sample prep; data analysis with Proteome Discoverer, Compound Discoverer, MassHunter, Skyline, MaxQuant, FragPipe, MS-Dial; programming (R, Python) a plus; strong communication and teamwork; U.S. citizen with ability to obtain interim secret th...
Mass spectrometry instruments, LC-MS/MS, MALDI-TOF, Proteomics software, R, Python, Proteome Discoverer, Compound Discoverer, MassHunter, Skyline, MaxQuant, FragPipe, MS-Dial
3w
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Manager AI Excellence (Frederick, MD, US, 21703)
Frederick, Maryland, United States
OnsiteFull Time
Bachelor’s in engineering, computer science, data science, or related field; experience leading AI initiatives; strong program management, communication, and cross-functional collaboration.
Python, Data Analytics
3w
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Program Associate
Harrisburg, Pennsylvania, United States
OnsiteFull Time
3+ YOEBachelor’s degree in a related field plus 3 years’ experience, or a related Master’s degree; field-based agronomic research experience; data management; willingness to travel statewide.
Excel, R, Python, Geospatial tools, UAV platforms
3w
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Program Associate
Harrisburg, Pennsylvania, United States
OnsiteFull Time
3+ YOEBachelor’s degree in Agronomy/Soil Science/Crop Science or related field with 3 years of experience, or related Master’s degree; field-based agronomic research experience; soil/plant sampling; willingness to travel statewide.
Excel, R, Python, UAV, Proximal sensors, Data loggers, Microsoft Word, GIS
3w
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Technical Product Manager
Frederick, Maryland, United States
$120k-$145k/yr HybridFull Time
7+ YOE7+ years software development with client-facing and leadership experience; full-stack delivery; strong communication and architectural skills.
PHP/Laravel, Node.js/TypeScript, .NET, Python, React, Databases, Cloud platforms
2mo
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Application Integration Specialist
Lancaster or Allentown or Chambersburg or Reading or York or Mechanicsburg or Exton
$75k-$85k/yr HybridFull Time
3+ YOEDesign, develop, and maintain secure application integrations using APIs, AI, and automation; collaborate with stakeholders; ensure security; document and upgrade systems.
PowerShell, Power Automate, APIs, Azure OpenAI, Private AI, Power BI, Python, SQL, Smartsheet
1mo
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SAP BTP Architect
Harrisburg, Pennsylvania, United States
RemoteFull Time
10+ YOE10+ years development experience; 3+ years SAP BTP; SAP Certified Professional – Solution Architect; ABAP, Fiori/UI5; cloud, DevOps, CI/CD; leadership experience.
SAP BTP, Cloud Foundry, Kyma, ABAP, Fiori, UI5, Node.js, Java, Python, DevOps, Azure DevOps, Jira, Confluence, Git
HiringCafe market data
Python Developer Jobs market signals in Guilford, PA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
51
Hiring companies
37
Fresh sample
54% new in 30d
Salary visibility
54% show pay
Companies appearing in this market
ForterraAxle InformaticsCape Fox Federal IntegratorsDeloitteHuntingtonJohnson ControlsMid Penn BankSelect Medical
Work location mix in visible results
Onsite: 29Hybrid: 13Remote: 8