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Python Software Developer Jobs in Columbus, IN, US
46 python software developer jobs from 24 companies hiring in Columbus, IN, US.
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Senior Software Engineer
Plano or Columbus or Boston or Portsmouth or Indianapolis
$106k-$197k/yr HybridFull Time
5+ YOEFive+ years software engineering; strong Python/Java; AWS; RESTful services; React/Node.js; Agile experience.
Python, Java, React, Node.js, Spring Boot, AWS, RESTful services, RDS
1d
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Software Engineer, AI & Clinical Applications
Indianapolis, Indiana, United States
$65k-$158k/yr HybridFull Time
3+ YOE3+ years full-stack development with Python; AI/LLM experience; regulated clinical environment knowledge; strong communication.
Python, JavaScript, TypeScript, SQL, R, React, Vue.js, FastAPI, Flask, Node.js, GraphQL, Pandas, NumPy, PySpark, SAS, SAS Viya, CDISC SDTM, ADaM, AWS, Azure, Docker, CI/CD, Git, PostgreSQL, SQL Server, Oracle, 21 CFR Part 11, MCP, LangChain, LangGraph, AutoGen
2mo
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Senior Software Engineer
Indianapolis, Indiana, United States
$80k-$100k/yr HybridFull Time
4+ YOE4+ years software development; Django experience; cloud deployment; REST APIs; HTML/CSS/JavaScript; Postgres; CI/CD; AI exposure (nice to have).
Django, Python, REST, PostgreSQL, HTML, CSS, JavaScript, Google Cloud Platform, CI/CD
1w
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Software Engineer, Senior
Indianapolis, Indiana, United States
OnsiteFull Time
5+ YOESenior software engineer with 5+ years experience, cloud-native apps, CI/CD, REST APIs, databases, and strong communication
C#, DotNet, Python, REST, SQL, PostgreSQL, DynamoDB, MongoDB, React, TypeScript, Terraform, Kubernetes, Docker, AWS
1mo
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Software Engineer I WSI
Indianapolis, Indiana, United States
OnsiteFull Time
Entry-level software engineer with C++, Python, or Java; Git; RTOS; avionics interfaces MIL-STD-1553/1760; Ethernet; scripting; testing and documentation.
C++, Python, Java, Git, GitHub, RTOS, MIL-STD-1553, MIL-STD-1760, Ethernet, UART, SPI, I2C, Qt, JUnit, pytest, Jenkins, GitHub Actions, Bash
2mo
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Sr. R&D Software Engineer
Boise or Indianapolis or Dallas or Farmers Branch
OnsiteFull Time
Lead software teams; strong mentorship; experience with C++, Python; ROS; Linux; CI/CD; design and architecture of software for robotics.
C++, Python, Linux, Git, ROS, Docker, Singularity, OpenCV, PCL, HTML, CSS, JavaScript, CANOpen, Serial, SPI, Ethernet/IP, Sockets
1w
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Sr. Product Software Engineer - AI
Coppell or Tampa or Kennesaw or Riverwoods or Chicago or Wichita or Indianapolis or Greenwood Village
$93k-$162k/yr HybridFull Time
3+ YOE3+ years software development; full-stack; Agile/XP with TDD/BDD and pair programming; experience with AI tools and ML workflows.
Python, JavaScript/TypeScript, GitHub Copilot, LangChain, Hugging Face, OpenAI, Azure AI, GenAI tools
1mo
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Principal Software Engineer
Indianapolis, Indiana, United States
$140k-$180k/yr HybridFull Time
8+ YOE8+ years software engineering; TypeScript, Node.js, React; distributed systems; cloud (AWS/GCP); SQL; data pipelines; ML workflows a plus; remote-friendly.
TypeScript, Node.js, React, Vue.js, Python, SQL, Snowflake, BigQuery, dbt, Airflow, AWS, Google Cloud, GitHub Copilot, Claude Code
3w
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Sr. Innovation Software Engineer
Minnetonka or Austin or Chicago or Easton or Dallas or Detroit or Hagerstown or Atlanta or Houston or Akron or Birmingham or Charlotte or Indianapolis or Pittsburgh or Cincinnati or Cleveland
$77k-$154k/yr OnsiteFull Time
8+ YOESenior software engineer with full-stack, AI-enabled solution delivery; 8-12 years of experience.
Java, Python, TypeScript/JavaScript, Vertex AI, Google Cloud
1mo
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Software Engineer (R&D)
Bloomington, Indiana, United States
$150k-$250k/yr RemoteFull Time
Strong programming fundamentals, able to work independently, across domains, write readable code, and use AI tools to move faster.
Python, C++, Git, LLMs, Automation frameworks
5d
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2026 Raytheon Full Time- Software Data Engineer II (Onsite)
Indianapolis, Indiana, United States
$69k-$131k/yr OnsiteFull Time
Master’s degree in CS/Software/Data Eng or related; Python and SQL; JavaScript/HTML/CSS; Agile; data engineering concepts.
Python, SQL, Git, dbt, Docker, Kubernetes, HTML, CSS, JavaScript
23h
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Senior Firmware Developer Engineer
Columbus, Indiana, United States
HybridFull Time
7+ YOE7+ years of firmware development; embedded Linux; C++, Python; CI/CD; OSS management; hardware debugging; cybersecurity exposure.
Embedded Linux, C++, Python, Yocto, Buildroot, OpenWRT, Azure DevOps, Jenkins, OSS (Open Source Software)
2w
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Senior Software Engineer - Aerospace Controls
Indianapolis or West Lafayette
$91k-$148k/yr HybridFull Time
2+ YOESenior software engineer with embedded safety-critical experience; DO-178C familiarity; US citizen.
Python, C, C++, Groovy, Simulink, Jenkins
1w
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Senior Engineer, Control Systems Simulation
Indianapolis, Indiana, United States
OnsiteFull Time
7+ YOE7+ years software engineering in C, C++, C#, Python, Rust; develop data-collection/tools for embedded controls; GitHub; Visual Studio/VS Code; BS in engineering or CS.
C, C++, C#, Python, Rust, GitHub, Visual Studio, VS Code, Veristand, LabView, Matlab, Simulink, CMMI, SPICE
2mo
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Senior Full-Stack Engineer
Culver City or Linthicum or Allen or Woodcliff Lake or Chicago or Orlando or Baton Rouge or Waltham or Phoenix or Harrisburg or West Valley City or Austin or Alpharetta or San Diego or Indianapolis or Lexington or Parma or Little Rock or Asheville or Birmingham or Chantilly or Washington or Brentwood or Plantation or Fort Collins or San Mateo or Schaumburg or Brooklyn
$140k-$180k/yr OnsiteFull Time
7+ YOE7+ years in software development; Bachelor's degree in CS/Engineering; backend (Node.js) and frontend (React) experience; API integrations; cloud and database experience.
Node.js, HapiJS, Python, JavaScript, React, SQL, Serverless, Lambda, CloudFormation, Elastic Beanstalk, EC2, VPC, DynamoDB, RDS, G Suite, Microsoft Graph, Okta, OneLogin, Slack, Linux, Docker, Datadog, CloudWatch, MQTT, log/data pipelines
1w
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Employee Success Lead Data Engineer
Indianapolis or Atlanta or Austin
HybridFull Time
10+ YOELead data engineer with 10+ years of experience in data engineering, data modeling, ML, automation, analytics; strong SQL, Python; API development; experience with AWS, Data360, Snowflake preferred.
SQL, Python, Informatica IICS, dbt, Apache Airflow, Git, AWS, Salesforce Data360, Snowflake, Bash
6d
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Sr. AI Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
5+ YOE5+ years AI/ML engineering; senior-level experience; production AI agents; large-scale enterprise data; AWS Bedrock/Lambda; RAG and MCP; Python, PyTorch/TensorFlow; security/compliance.
AWS Bedrock, AWS Lambda, Python, PyTorch, TensorFlow, SQL, PySpark, LangChain, LangGraph, vector databases
1mo
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Solutions Engineer/Technical Lead, Software (Guidewire Policy Center)
Plano or Columbus or Boston or Portsmouth or Indianapolis
HybridFull Time
10+ YOEStrong software integration expertise with Guidewire, GWCP, API-first design, Java/Spring, cloud and DevOps, and experience with Guidewire InsuranceSuite.
Java, Spring Boot, JavaScript, TypeScript, Node.js, Python, AWS, Kubernetes, Docker, PostgreSQL, NoSQL, Jenkins, GitLab CI, AWS CodePipeline, TeamCity, Cloud Foundry, APIs, GWCP, IG
4w
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Senior Salesforce Developer
Chicago or Los Angeles or New York or Oakbrook Terrace or Sacramento or San Francisco or South Bend or San Jose or Tampa or Atlanta or Boston or Columbus or Dallas or Denver or Fort Lauderdale or Grand Rapids or Houston or Austin or Charlotte or Indianapolis
$109k-$222k/yr HybridFull Time
5+ YOE5+ years Salesforce experience; proficient in Apex, Visualforce, Aura, LWC; strong frontend skills; Salesforce API; certifications preferred
Salesforce, Apex, Visualforce, Aura Components, Lightning Web Components, Salesforce API, Heroku, AWS, Python, Node.js
13h
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AI Engineer / Data Engineer (Indianapolis, IN / Onsite)
Indianapolis, Indiana, United States
$120k-$155k/yr HybridFull Time
3+ YOEStrong SQL, Python, ML/MLOps, data engineering, and software engineering skills with production AI/ML experience.
Python, SQL, PyTorch, TensorFlow, scikit-learn, MLOps, AWS, Azure, GCP, Snowflake, Docker, CI/CD
2w
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Senior DevOps Engineer
Indianapolis or Burnaby or Mesa
HybridFull Time
5+ YOE5+ years in Infrastructure as Code and software release pipelines; Bachelor's in Engineering or Computer Science; strong automation and cloud skills.
Azure DevOps, YAML, Terraform, ARM, Bicep, PowerShell, Python, Monitoring, IT Security
1w
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Senior Optical Engineer
Odon, Indiana, United States
$120k-$160k/yr OnsiteFull Time
7+ YOEBachelor’s in STEM with 10+ years or Master’s with 7+ years; ability to obtain US Secret clearance; multi-domain engineering leadership; EO/IR and sensor systems experience; system integration across hardware, firmware, and software.
C++, Python, MATLAB, FPGA, RF systems, Optical/photonic systems, Imaging systems, Lab instrumentation
1mo
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Payer Dev, Git & ML-Ops Engineer, Senior Associate
Boston or Indianapolis or Raleigh or Charlotte or Jacksonville or Chicago or Cincinnati or Cleveland or Columbia or Kansas City or Columbus or Dallas or Las Vegas or Los Angeles or Baltimore or Birmingham or St. Louis or Salt Lake City or San Diego or San Francisco or Silicon Valley or Seattle or Stamford or Tampa or Toledo or Austin or Washington or New York or Florham Park or Philadelphia or Phoenix or Pittsburgh or Houston
$77k-$202k/yr OnsiteFull Time
4+ YOEBachelor's degree; 4+ years software or data engineering; experience with dbt on Databricks; healthcare analytics experience; CI/CD pipelines for Databricks; Azure Databricks workspace provisioning; Python CLI tools.
Databricks, dbt, Azure Databricks, Python, YAML, argparse, CI/CD, AI agent systems
2mo
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Programmer
Indianapolis, Indiana, United States
OnsiteFull Time
2+ YOEProficient in AV programming, embedded systems, and control design; strong communication and problem-solving; 2+ years experience in AVI-SPL or 3+ external; Crestron/AMX/Extron/QSC knowledge; driver license.
Crestron CTI-P201, AMX Control Programmer Associate, Crestron Technician Fundamentals (CTI-CTF), AVIXA Essentials of AV Technology, C#, JavaScript, Lua, Python, HTML-5, PowerShell, Git, Crestron, AMX, Extron, QSC
1mo
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Business Process Automation Consultant
Indianapolis or Atlanta or Saint Louis or Louisville or Grand Prairie or Norfolk
HybridFull Time
7+ YOEBA/BS required; 7+ years relevant experience; 3+ years building RPA solutions with .NET or similar languages.
.NET, Python, UiPath, Alteryx, Web development, RPA
HiringCafe market data
Python Software Developer Jobs market signals in Columbus, IN, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
46
Hiring companies
24
Fresh sample
59% new in 30d
Salary visibility
61% show pay
Companies appearing in this market
Eli Lilly and CompanyV2XCALRegionalHuntingtonTerran RoboticsLiberty MutualMoser ConsultingRTX
Work location mix in visible results
Onsite: 21Hybrid: 18Remote: 2