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Python Software Developer Jobs in Duxbury, MA, US
880+ python software developer jobs from 310+ companies hiring in Duxbury, MA, US.
2w
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Senior Security Engineer, Detection and Response
Austin or San Francisco or Seattle or Boston or Washington
$182k-$202k/yr RemoteFull Time
5+ YOE5+ years in detection and response or security engineering; strong software fundamentals; experience with cloud (AWS); experience with log analysis and endpoint detection tools.
Python, Go, Ruby, CloudTrail, GuardDuty, VPC flow logs, Datadog, Splunk, ELK, SentinelOne, CrowdStrike
1w
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Site Reliability Engineer I
Boston or Milwaukee or Maitland
$53k-$90k/yr HybridFull Time
1+ YOE1-3 years of experience in SRE, Technical Support, or Software Engineering; Bachelor's degree in Computer Science or Computer Engineering or equivalent experience; strong programming and scripting skills; cloud (AWS/Azure) experience.
C#, Java, Python, SQL, PostgreSQL, AWS, Azure, Git
1w
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Systems Engineer IV (West Greenwich, RI, US, 02817)
West Greenwich, Rhode Island, United States
$44k-$103k/yr OnsiteFull Time
9+ YOESenior systems engineer for architecting and implementing enterprise-scale software and infrastructure; leads design, standards, and mentoring.
Red Hat Linux, Windows Server, OpenShift, VMware ESXi, vSphere, IBM DB2, PostgreSQL, OpenLDAP, Red Hat IDM, Puppet, Ansible, AWS, Azure, Google Cloud, NetApp, Lenovo DM Storage, Ansible Playbooks, Red Hat Satellite, KSH, bash, Python, Java, Ruby
1mo
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Manager, Engineering
Raleigh or Chicago or Franklin or Boston
$148k-$175k/yr HybridFull Time
5+ YOE5+ Mgmt5+ years of technical leadership; 5+ years in operations optimization; tests, reports, and documentation experience; strong Python, Django, PySpark, ETL, SQL skills.
Python, Django, PySpark, ETL, SQL
2w
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Associate Director, Programming (Macros & Automation)
King of Prussia or Waltham or Glattbrugg
$189k-$220k/yr HybridFull Time
10+ YOE10+ years SAS programming, macro development, and automation leadership; knowledge of CDISC; strong collaboration.
SAS, SAS Macro, Python, R
1mo
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Research Scientist, AI/ML Agentic Systems
Boston, Massachusetts, United States
$116k-$182k/yr HybridFull Time
PhD in computer science, computational biology, bioinformatics, or related field; experience with large language models; Python; agentic AI frameworks; RAG systems; drug discovery knowledge.
Python, LangChain, AutoGen, CrewAI, LLM, Vector databases, ChEMBL API, PubMed API
4d
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Senior Tools Programmer
Boston, Massachusetts, United States
$119k-$218k/yr HybridFull Time
Extensive production C++ experience; full lifecycle tool development; strong communication; prioritize and deliver value.
C++, Unreal Engine, Slate, Editor Utility Widgets, Python, Blueprint
1mo
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Member of Technical Staff - Applied ML, RecSys
San Francisco or Boston or Remote
HybridFull Time
Hands-on experience building or fine-tuning recommendation models at scale; sequential recommendation architectures; data quality and evaluation design; large-scale data pipelines; Python and PyTorch proficiency.
Python, PyTorch, Large-scale data pipelines, Recommendation models
3mo
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Analog Design Automation Intern
Toronto or Boston or Austin or Santa Clara
$35-$70/hr HybridInternship
Co-op or PEY student in Electrical Engineering with analog IC design exposure; Python proficiency; interest in ML concepts; open source tools; strong analytical and communication skills.
Python
2mo
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Solutions Architect
Boston or San Francisco
HybridFull Time
Strong systems thinking and coding; production systems; Python/Go/C++; web frameworks; PostgreSQL/Redis; REST/GraphQL; PyTorch/JAX; Kubernetes/Docker; Terraform; HPC/physics interest.
Python, Go, C++, React, TypeScript, Next.js, PostgreSQL, Redis, REST, GraphQL, PyTorch, JAX, Ray, Airflow, Argo, Docker, Kubernetes, Terraform, Prometheus, Grafana
1mo
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Manager, Data Science (GenAI Solutions & ML Engineering) (Boston, MA, US, 02110)
Boston, Massachusetts, United States
$131k-$164k/yr OnsiteFull Time
5+ YOE3+ MgmtBachelor’s degree; 5+ years in Machine Learning Engineering, Applied AI, or MLOps; 3+ years leading technical teams; strong end-to-end AI systems; Python and PyTorch; enterprise integration.
Python, PyTorch, ML frameworks
1mo
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Solutions Architect
Boston, Massachusetts, United States
$175k-$210k/yr HybridFull Time
7+ YOE7+ years in Solutions Architecture/Applied Engineering for enterprise SaaS or ML/LLM products; strong system design; LLM/AI familiarity; practical coding (JS/Node/TS or Python); excellent writing; CX/Support stack experience a plus.
JavaScript, Node.js, TypeScript, Python, REST, GraphQL, APIs, webhooks, ETL, iPaaS
3mo
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Security Researcher / Systems Hacker
Lexington, Massachusetts, United States
$140k-$200k/yr OnsiteFull Time
3+ YOEMS or PhD in a related field with extensive systems software research and development experience; strong C/C++, Python, and assembly; security clearance eligibility.
C/C++, Python, Assembly, Rust, LLVM, QEMU, Linux
1mo
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Research Intern – Advanced Solution Development
Framingham, Massachusetts, United States
OnsiteInternship
Master’s or PhD candidate in CS or related field; strong AI/ML background; proven research ability; prior software development preferred.
LLM, Python, Machine Learning, Research Frameworks
1mo
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Lead AI Solutions Architect - Full Stack
Princeton or Glen Allen or Coppell or Waltham or Philadelphia or Riverwoods or New York City or Chicago or Houston
$129k-$226k/yr HybridFull Time
10+ YOELeadership-focused AI solutions architect with 10+ years in full-stack engineering, GenAI/Agentic AI, data science, AI/ML, and applied AI engineering; proven leadership and mentoring experience.
Python, FastAPI, Angular, React, LangChain, LlamaIndex, SQL, NoSQL, Azure, AWS
2mo
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Algorithmic Trading Internship - Boston Summer 2026
Boston, Massachusetts, United States
$50/hr RemoteInternship
0+ YOECuriosity, self-motivation, strong communication, collaborative, problem-solving, and programming skills.
Python, C#, Java, C++
1d
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Director, Application Engineering
Newton, Massachusetts, United States
$170k-$215k/yr HybridFull Time
7+ YOE5+ MgmtLead strategy, architecture, and delivery of mobile apps and GenAI capabilities; manage engineering teams; cloud SaaS experience; strong collaboration with product and security.
Angular, Ionic, React Native, Flutter, iOS, Android, Python, Perl, CI/CD, Cloud, AI governance, LLM tools, Observability, APM
9h
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Entrepreneur in Residence - Technical Co-founder (CTO)
Boston or United States
RemoteFull Time
Experience shipping AI products; strong system design; founder mindset; willingness to co-found with equity; fundraising experience a plus.
Python, LLM, Frontier Models, Distributed Systems
1d
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AI Product Builder
Boston, Massachusetts, United States
HybridFull Time
1+ YOE1–3 years in product, engineering, data, or analytics; strong AI tooling, prototyping, and data pipeline experience.
Claude, Cursor, GPT, Git, AI prototyping, Python
1d
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Policy Analyst, Geospatial Data Science (53231)
Cambridge, Massachusetts, United States
$65k-$74k/yr OnsiteMultiple Commitments Available
3+ YOEGraduate degree in geography/planning/economic policy or related field; 3–5 years geospatial data analysis; proficiency in Python/R/Stata; GIS software; strong communication; independent work.
Python, R, Stata, Git, GitHub, GitLab, ArcGIS Pro, Google Earth Pro
3w
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Sr. Manager, Investments Technology
Boston or Houston or Atlanta
$185k-$195k/yr HybridFull Time
10+ YOE3+ Mgmt10+ years in software engineering with 3–5+ years leading teams; strong system design; AI-enabled development; Python and AWS; FinOps; CFA/CPA/CIPM/CAIA/FRM preferred.
Python, AWS, Docker
3mo
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Data Science Intern - Summer 2026 - Bedford, MA
Bedford, Massachusetts, United States
$40-$50/hr HybridInternship
5+ YOEMaster’s in CS/Engineering/OR or related field; 5+ years data analysis and software development; Python, C/C++/C#; ML/AI experience; strong math/statistics; cloud/LLM a plus; US work authorized.
Python, C++, C#, C, Machine Learning, LLM, MLops, Cloud
1mo
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AI Development Lead
United States or Jupiter or New York or Arlington or Boulder or Chicago or Atlanta or Boston
$118k-$196k/yr RemoteFull Time
7+ YOE2+ MgmtSeven+ years delivering AI/software/data solutions; two+ years in leadership; hands-on Generative AI in cloud; Python with AI/LLMs; Agile/DevOps delivery; strong communication.
Python, LangChain, LangGraph, AWS, Azure, SageMaker, Bedrock, LLMs, APIs, SDKs
2w
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Senior Manager, Machine Learning
San Jose or Waltham
$152k-$265k/yr OnsiteFull Time
8+ YOE3+ MgmtEight+ years of software development experience with at least 3 years in management; strong background in generative AI, LLMs, ML model development, and production deployment.
Python, ML Pipelines, MLOps, Cloud Services, Generative AI, LLMs, Claude Code, Cursor AI
1mo
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Associate Director, Biostatistics - Genetic Medicine
Tarrytown or Warren or Cambridge
$176k-$287k/yr OnsiteFull Time
6+ YOEPhD or equivalent in statistics/biostatistics with >6 years in pharma OR MS in statistics/biostatistics with >11 years; hematology/IO experience preferred; TTE experience; strong leadership and collaboration skills; proficient in statistical software.
SAS, R, Python
2mo
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Industrial AI Applications Lead
Philadelphia or Boston or New York
$225k-$375k/yr HybridFull Time
10+ YOE10+ years in industrial systems or AI-enabled software with 3+ years in a customer-facing technical lead role; BS in CS/Engineering/Industrial Systems; strong industrial domain knowledge; hands-on AI deployment; cross-functional leadership.
Python, Machine Learning, TensorFlow, PyTorch, Cloud, Industrial Control Systems
1mo
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Enterprise Data Architect & Integration Lead
Providence, Rhode Island, United States
HybridFull Time
10+ YOE5+ Mgmt10+ years in data architecture, software development, or system integration; leadership experience; strong data modeling, API design, and SDLC governance.
Databricks, Snowflake, Microsoft Fabric, REST, GraphQL, SOAP, Webhooks, GitHub, CI/CD, Power Apps, Power Automate, PowerShell, Python, JSON, Node.js, Azure, AWS, Google Cloud
2mo
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Research and Development Solution Architect - Digital Lab Operations
Morristown or Cambridge
$134k-$193k/yr OnsiteFull Time
5+ YOE5-8+ years of solution architecture experience; CS/IS/Software Engineering background; strong IT governance, GxP, HIPAA, GDPR knowledge; English communication; vendor management; cross-functional collaboration.
Snowflake, GitHub, IICS, Python, OpenShift, ReactJS, SQL, AWS, Azure
HiringCafe market data
Python Software Developer Jobs market signals in Duxbury, MA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
880+
Hiring companies
310+
Fresh sample
41% new in 30d
Salary visibility
76% show pay
Companies appearing in this market
Liquid AIAdobeAlegeusAspenTechAVEVABisnowBright HorizonsBrightstar Lottery
Work location mix in visible results
Hybrid: 17Onsite: 8Remote: 4