Explore 78 python software developer jobs from 35 hiring companies in Middletown, RI, US. Filter by remote, salary, experience, and company, then open any listing to apply.

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Python Software Developer Jobs

Moderna

PKF O'Connor Davies

Hybrid

Modernatx

The RoleThe Sr. Digital Manufacturing Technical Specialist will lead the design and deployment of scalable AI capabilities across Moderna’s Global Drug Substance (DS) Network. This role is accountable for translating complex operational challenges into robust, production-grade AI solutions that drive measurable impact across manufacturing, supply chain, and quality.As a technical leader, this individual will operate with a high degree of autonomy, influence cross-functional stakeholders, and build reusable AI systems that can scale across sites and functions in a regulated (GxP) environment.Here&#39;s What You’ll Do<ul><li>Own end-to-end delivery of AI solutions from problem framing through deployment, monitoring, and continuous improvement across DS operations</li><li>Design scalable AI systems (e.g., LLM-powered applications, RAG pipelines, predictive models) that can be reused across the Global DS Network</li><li>Translate ambiguous business problems into structured AI use cases, partnering with SMEs across manufacturing, MS&amp;T, quality, and supply chain</li><li>Drive adoption and value realization by embedding AI solutions into existing workflows and enterprise platforms</li><li>Ensure compliance and reliability of AI systems within GxP and data integrity frameworks</li><li>Establish best practices for AI development, evaluation, and lifecycle management within the DS domain</li><li>Influence technical direction and contribute to AI strategy for manufacturing and supply chain use cases</li><li>Mentor and uplift others, contributing to capability building and AI fluency across the network</li></ul>Here’s What You’ll Need (Basic Qualifications) <ul><li>Bachelor’s or Master’s degree in Computer Science, Engineering, Data Science, or a related field</li><li>2-4 years of experience delivering AI/ML or advanced analytics solutions in production environments</li><li>Strong software engineering skills with experience building scalable, maintainable systems</li><li>Hands-on experience with generative AI and LLM-based applications (e.g., prompt engineering, RAG, APIs)</li><li>Experience working with cloud platforms</li><li>Demonstrated ability to work across functions and influence stakeholders without direct authority</li><li>At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.</li></ul>Pay &amp; BenefitsAt Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.<ul><li>Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs</li><li>A holistic approach to well-being, with access to fitness, mindfulness, and mental health support</li><li>Family planning benefits, including fertility, adoption, and surrogacy support</li><li>Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown</li><li>Savings and investment opportunities to help you plan for the future</li><li>Location-specific perks and extras</li></ul>The salary range for this role is $100,400.00 - $160,700.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.&amp;#xa;&amp;#xa;The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit <a target="_blank" href="https://www.modernatx.com/en-US/careers/life-at-moderna">modernatx.com/careers</a> to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal OpportunitiesModerna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person&#39;s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. AccommodationsWe’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at <a target="_blank" href="mailto:leavesandaccommodations&#64;modernatx.com">leavesandaccommodations&#64;modernatx.com</a>. Export Control Notice&amp;#xa;This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.&amp;#xa;#LI-SB2-

Sr. Digital Manufacturing Technical Specialist

Digital Manufacturing Technical Specialist

BS/MS in CS/Engineering/Data Science; 2-4 yrs AI/ML in production; strong software engineering; GenAI/LLM; cloud platforms; US work authorization.

About PKF O’Connor Davies 
PKF O’Connor Davies is a top-ranked accounting, tax, and advisory firm with offices across the U.S. and internationally through our PKF global network. For over a century, we have built our reputation on deep industry expertise, a personalized approach, and a commitment to delivering real value to our clients.
Our mission is to provide exceptional service while fostering long-term relationships built on trust and integrity. We serve a diverse client base across industries and sectors, helping organizations and individuals navigate complex challenges with confidence.
At PKF O’Connor Davies, culture is at the heart of who we are. We believe our team members are our greatest asset, and we invest in their growth and success through mentorship, professional development, and continuous learning opportunities. Our goal is to foster a collaborative environment where diverse perspectives are valued, innovation is encouraged, and team members can make an impact. We are also committed to supporting work–life balance, offering flexibility and resources to help our team members grow their careers while maintaining fulfilling personal lives.
If you are looking for a career where you can grow, contribute, and be part of a firm that values both excellence and community, PKF O’Connor Davies is the place for you!
We are seeking an experienced Enterprise Data Architect & Integration Lead to own and drive our organization’s data architecture strategy while leading development and integration practices. This role combines hands-on architecture with team leadership, serving as a key bridge between data strategy, application development, and enterprise integration.
The successful candidate will act as a player-coach, guiding a distributed team of developers while defining and implementing scalable, secure, and governed data and integration solutions. This individual will build upon an established SDLC and development framework to ensure continued maturity, adoption, and alignment with enterprise architecture standards.
This is a high-impact role responsible for shaping the firm’s data and integration landscape. The Enterprise Data Architect & Integration Lead will play a central role in enabling scalable systems, improving data accessibility and quality, and driving long-term technology strategy.
Office Location: Any PKFOD office 
Key Responsibilities
Data & Integration Architecture
<ul>
<li>Own and drive the firm’s enterprise data architecture strategy, including data modeling, data flows, and platform design</li>
<li>Define and implement a data architecture roadmap aligned with business goals and system integration needs</li>
<li>Establish standards for data modeling, data storage, and data lifecycle management</li>
<li>Design and oversee data pipelines, ETL/ELT processes, and real-time data integrations</li>
<li>Define and enforce data governance practices, including data quality, lineage, security, and access controls</li>
<li>Partner with stakeholders to ensure data architecture supports reporting, analytics, and operational use cases</li>
<li>Align application and integration design with enterprise data architecture principles</li>
</ul>
Integration & Automation Strategy
<ul>
<li>Define and lead the enterprise integration strategy, including APIs, workflows, and system connectivity</li>
<li>Design and oversee API architectures and integration patterns (REST, GraphQL, event-driven, etc.)</li>
<li>Guide the development of automation solutions and workflows to streamline business processes</li>
<li>Ensure integrations are scalable, secure, and aligned with enterprise standards</li>
<li>Collaborate with business teams and vendors to deliver robust integration solutions</li>
</ul>
Software Development & SDLC Ownership
<ul>
<li>Own and evolve the firm-wide Software Development Lifecycle (SDLC) to ensure consistency, quality, and scalability</li>
<li>Ensure adoption of development standards including code quality, testing, documentation, and deployment practices</li>
<li>Define and maintain the development toolchain and platforms (e.g., GitHub, CI/CD pipelines, environments)</li>
<li>Promote best practices across version control, branching strategies, and release management</li>
</ul>
Team Leadership & Mentorship
<ul>
<li>Lead and mentor a distributed team of early-career developers focused on automation and integration</li>
<li>Provide coaching, career development, and technical guidance to grow team capabilities</li>
<li>Foster a collaborative, high-performing, and accountable team culture</li>
<li>Act as a technical leader and escalation point for complex development and integration challenges</li>
</ul>
Qualifications
<ul>
<li>Bachelor’s or Master’s degree in Computer Science, Information Technology, or a related field</li>
<li>10+ years of experience in data architecture, software development, or system integration, including leadership experience</li>
<li>Proven experience designing and implementing enterprise data architectures and integration solutions</li>
<li>Strong experience with data modeling, database design, and data pipeline architecture</li>
<li>Experience with ETL/ELT tools and modern data platforms (e.g., Databricks, Snowflake, Microsoft Fabric)</li>
<li>Hands-on experience with API design and integration technologies (REST, GraphQL, SOAP, Webhooks)</li>
<li>Strong knowledge of software development best practices and SDLC frameworks</li>
<li>Experience with development tools and CI/CD pipelines (e.g., GitHub, automated testing frameworks)</li>
<li>Proficiency in technologies such as Power Apps, Power Automate, PowerShell, Python, JSON, Node.js</li>
<li>Familiarity with cloud platforms (Azure, AWS, or Google Cloud)</li>
<li>Understanding of data governance, security, and compliance best practices</li>
<li>Experience working with Active Directory and enterprise application environments</li>
<li>Demonstrated success leading and mentoring distributed or global teams</li>
<li>Strong communication, stakeholder management, and problem-solving skills</li>
</ul>
Preferred Qualifications
<ul>
<li>Experience with Azure Logic Apps and Microsoft Fabric</li>
<li>Experience implementing data governance frameworks or tools (e.g., cataloging, lineage, quality monitoring)</li>
<li>Exposure to modern data architectures (data lakehouse, data mesh, event-driven systems)</li>
<li>Relevant certifications in cloud platforms, data architecture, or software development</li>
</ul>
Compensation & Benefits: 
Actual compensation will be dependent upon the specific role, office location as well as the individual’s qualifications, experience, skills, and certifications. 
At PKFOD, we value our team members and are committed to their success and well-being. As part of our comprehensive benefits and compensation package, we offer:
<ul>
<li>Medical, Dental, and Vision plans</li>
<li>Basic Life, AD&D, and Voluntary Life Insurance</li>
<li>401(k) plan and Profit-Sharing program</li>
<li>Flexible Spending & Health Saving accounts</li>
<li>Employee Assistance, Wellness, and Work-life programs</li>
<li>Commuter & Parking benefits programs</li>
<li>Inclusive Parental Leave Benefits</li>
<li>Generous Paid Time Off (PTO)</li>
<li>Paid Firm Holidays</li>
<li>Community & Volunteering programs</li>
<li>Recognition & Rewards programs</li>
<li>Training & Certification programs</li>
<li>Discretionary Performance Bonus</li>
</ul>
*Eligibility for benefits is determined based on position, hours worked, and other criteria. Specific details will be provided during the hiring process. 
We are interested in all qualified candidates who are currently authorized to work in the United States. However, we are not able to sponsor work visas.
PKFOD is an equal opportunity employer. The Firm is committed to providing equal employment opportunity to all persons in connection with hiring, assignment, promotion, compensation or other conditions of the employment relationship regardless of race, color, age, sex, marital status, disability, pregnancy, citizenship, philosophy/religion, national origin, sexual orientation, gender identity, military or veteran status, political affiliation or belief, or any other status protected by federal, state or local law.
To all staffing agencies: PKF O'Connor Davies Advisory, LLP (“PKFOD”) will not be utilizing agencies to staff this position. Please do not forward resumes to PKFOD partners and/or employees at any of our locations regarding this position. Any recruiter who would like to partner with PKFOD on other positions must have an updated contractual agreement with PKFOD through the Director of Talent Acquisition. Please be reminded, PKFOD is not responsible for any fees related to unsolicited resumes. All unsolicited resumes will become the property of PKFOD.
#LI-NK
#LI-Hybrid

Enterprise Data Architect & Integration Lead

10+ years in data architecture, software development, or system integration; leadership experience; strong data modeling, API design, and SDLC governance.

Python Software Developer Jobs in Middletown, RI, US | HiringCafe: every job on earth

Python Software Developer Jobs in Middletown, RI, US

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