📣 HiringCafe is hiring a Founding Growth Hacker! Learn More · Apply here
Senior Python Developer Jobs in Danville, VA, US
92 senior python developer jobs from 31 companies hiring in Danville, VA, US.
2mo
Save
Mark Applied
Hide
Senior Systems Software Engineer
Durham, North Carolina, United States
$121k-$277k/yr HybridFull Time
6+ YOESenior software engineer with 6-10 years of experience; proficient in Python and Kubernetes; strong software design and testing skills.
Python, Kubernetes, Software Testing, APIs, Distributed Systems
1mo
Save
Mark Applied
Hide
Senior Software Engineer/Developer
Durham, North Carolina, United States
HybridFull Time
3+ YOEDevelop cloud-native financial services software using Java, Python, AWS, Kafka; plus testing, CI/CD, and cloud infrastructure experience.
Java, Java/J2EE, Spring Boot, RESTful APIs, Python, Apache Kafka, Docker, Kubernetes, AWS, AWS EKS, Lambda, SQS, S3, CloudWatch, IAM, PostgreSQL, CockroachDB, Jenkins, Terraform, Datadog, Splunk, JUnit, Mockito, SonarQube, Cucumber
3d
Save
Mark Applied
Hide
Senior Software Engineer
Raleigh or Durham
$174k-$252k/yr RemoteFull Time
5+ YOEBachelor's degree or equivalent; 5 years in OO programming (Java/C++/Python); 3 years testing/maintaining/launching software; 1 year in design/architecture; preferred: advanced degrees, data structures/algorithms, technical leadership, accessible tech.
Java, C++, Python, Testing, Software Design
2mo
Save
Mark Applied
Hide
HPE Morpheus Software - Senior Software Engineer
Fort Collins or Houston or Durham
$144k-$273k/yr HybridFull Time
8+ YOE8+ years experience in backend software development with Java/Python/Groovy/Ruby, Linux, REST APIs, cloud, CI/CD, virtualization, ITSM; strong design, documentation, and collaboration skills.
Java, Groovy, Ruby, Python, Linux, REST, SQL, NoSQL, CI/CD, Maven, Gradle, Git, AWS, Azure, GCP, VMware
3d
Save
Mark Applied
Hide
Senior Clinical Programmer I (Python)
Durham, North Carolina, United States
HybridFull Time
5+ YOEBachelor’s degree with at least 5 years of professional programming experience in Python/SAS/R/SQL and dashboard technologies.
Python, SAS, R, SQL, Power BI, Spotfire
2mo
Save
Mark Applied
Hide
HPE Morpheus Software - Senior Software Engineer
Ft. Collins or Houston or Durham
$137k-$315k/yr HybridFull Time
8+ YOEBackend-focused software engineer with strong Java/Python/Linux experience; RESTful APIs, CI/CD, cloud knowledge; 8+ years, Bachelor’s in CS/Engineering.
Java, Python, Groovy, Ruby, Linux, RESTful APIs, SQL, NoSQL, Maven, Gradle, Git, CI/CD, AWS, Azure, Google Cloud
23h
Save
Mark Applied
Hide
Senior System Software Engineer, Holoscan
Santa Clara or Durham County or United States
$184k-$288k/yr HybridFull Time
6+ YOE6+ years in system software; BS in CS/Software Eng; strong C/C++, Python; embedded/Linux; security basics
C/C++, Python, Bash, Docker, CMake, Linux, Yocto, LLM, AI tooling
2w
Save
Mark Applied
Hide
AI/ML Development Senior Engineer
Durham or Lowell or Morgan Hill
OnsiteFull Time
5+ YOEBachelor’s or Master’s in CS/AI/DS; 5-10 years AI/ML engineering; Python and ML frameworks; agentic AI; cloud-based architectures; collaboration across teams.
Python, Pandas, PyTorch, TensorFlow, LangChain, OpenAI, Anthropic, AWS Bedrock, SageMaker, Hugging Face
1mo
Save
Mark Applied
Hide
Senior Staff Engineer - Nutanix Kubernetes Platform (NKP)
Bangalore or San Jose or Durham or Mexico City or Pune or Hoofddorp or Belgrade or Barcelona or Singapore or Sydney or Tokyo
HybridFull Time
15+ YOE15-20+ years in software development; cloud-native, distributed systems; Go/Python/Java; Kubernetes internals a plus; leadership and mentoring; BS/MS/PhD in Computer Science.
Go, Python, Java, Kubernetes, Docker
2w
Save
Mark Applied
Hide
Senior Lead Software Engineer
Durham or Burlington
HybridFull Time
6+ YOE6+ years of software engineering experience, US-based, proficiency in Python, TypeScript, Kotlin; cloud (AWS); Kubernetes; IaC; and cross-team leadership.
Python, TypeScript, Kotlin, AWS, Kubernetes, Infrastructure as Code
2w
Save
Mark Applied
Hide
Senior Quant Engineer (Open to Remote)
White Plains or Jersey City or Home Base or Home Base or Greensboro or Raleigh or Home Base
$234k-$317k/yr RemoteFull Time
10+ YOE10+ years in quantitative engineering or front-office tech; strong Python; experience with major market data vendors.
Python, REST APIs, Bloomberg, ICE, FactSet, Kamakura, LSEG
2w
Save
Mark Applied
Hide
Senior Product Engineer RF and ADC
Wilmington or Durham
$110k-$152k/yr OnsiteFull Time
5+ YOESenior engineering role focused on RF and high-speed data converter development, qualification, automation, and cross-functional leadership.
Python, MATLAB, RF measurement tools, lab equipment
1w
Save
Mark Applied
Hide
Senior Electronics Test Engineer
Greensboro, North Carolina, United States
OnsiteFull Time
Bachelor's degree in electrical/electronic engineering; strong testing/troubleshooting experience; ICT and functional testing; LabVIEW, Visual Basic, C++, Python; troubleshoot TCP/IP networks; electronics design; proficient with Microsoft apps.
LabVIEW, Visual Basic, C++, Python, PLC programming, TCP/IP, Lab equipment
1w
Save
Mark Applied
Hide
IIoT Senior Solution Engineer
Liberty, North Carolina, United States
OnsiteFull Time
5+ YOE5+ years in industrial automation/IIoT, SCADA/HMI, or IIoT architecture; 3+ years with Ignition; proficient in Python, .NET/C#, Typescript; PLC experience; MQTT/OPC UA; SQL; strong problem solving; Bachelor's degree or equivalent experience.
Ignition, .NET, Typescript, Angular, Python, Jython, SQL, MQTT, OPC UA, PLC, Docker, Kubernetes, MCP, Linux, Copilot
1w
Save
Mark Applied
Hide
Senior Algorithm Developer - PySpark / SQL (Durham, NC, US)
Durham, North Carolina, United States
OnsiteFull Time
5+ YOE3+ years PySpark/Python in production; 5+ years SQL; Spark ecosystem; AWS; CI/CD; Git/JIRA; agile teams.
PySpark, Python, SQL, Apache Spark, AWS, Git, JIRA, CI/CD, Iceberg, EMR, S3, CloudWatch
1mo
Save
Mark Applied
Hide
Senior Data Engineer
Durham or Pleasanton
$107k-$252k/yr HybridFull Time
5+ YOE7+ years in data engineering; cloud platforms (Azure); Python, Spark, SQL; BI tools (Power BI, Tableau); data governance and quality.
Python, Spark, SQL, Pandas, Power BI, Tableau, Azure, Databricks, Delta Lake, CI/CD, ML Ops, Gen AI
1mo
Save
Mark Applied
Hide
Software Engineer (AI/ML Interface Development)
San Diego or Nashua or Greenlawn or Durham
$92k-$157k/yr HybridFull Time
4+ YOEBS in CS/Software Engineering; 4+ years in software development; strong AI/ML interface experience; proficiency in Python, Java, C++; API/microservices; experience with LLMs and vector databases; Docker/Kubernetes; CI/CD; US Secret Clearance.
Python, Java, C++, Docker, Kubernetes, APIs, CI/CD, LLMs, vector databases
3w
Save
Mark Applied
Hide
IT Corporate Senior Systems Engineer
Austin or Durham or Kansas City or Lakewood or Salt Lake City or Sunnyvale
$136k-$169k/yr HybridFull Time
8+ YOE8+ years enterprise IT systems engineering; 5+ years Google Workspace; macOS/Apple MDM (Kandji/Iru); Microsoft Intune; SaaS deployment; Bachelor's degree or equivalent.
Google Workspace, Kandji, Iru, Microsoft Intune, Python, PowerShell, GAM, CrowdStrike, CatchPoint, GCP Cloud CLI, Okta, Entra ID
5d
Save
Mark Applied
Hide
Software Engineer III
Durham, North Carolina, United States
HybridFull Time
8+ YOE8+ years software engineering; Python; backend/platform; LLM-powered systems; orchestration patterns; APIs and cloud-native experience; Docker/Kubernetes; RAG pipelines; security and observability.
Python, LangGraph, CrewAI, AutoGen, LangChain, LlamaIndex, AWS, Azure, GCP, Docker, Kubernetes, CI/CD, OpenTelemetry, Langfuse, LangSmith, Arize Phoenix
2mo
Save
Mark Applied
Hide
Staff Engineer, AI Core
Palo Alto or Miami or Washington or Durham or Toronto
HybridFull Time
Experience as a Staff Engineer or Senior Engineer shipping complex, large-scale consumer-facing mobile apps; strong backend and AI/ML data-pipeline experience; leadership and mentorship.
Flutter, AWS, Go, Java, Python, Clojure, Microservices, Event-driven
3w
Save
Mark Applied
Hide
Principal Software Engineer
Durham, North Carolina, United States
RemoteFull Time
6+ YOEBachelor's or master's degree; 6+ years software engineering including 3+ years in energy systems or industrial controls; strong Python/Java/C/C++; real-time/embedded experience; EMS/SCADA familiarity; Linux-based deployments; cloud and containerization; knowledge of power systems and grid participation.
Python, Java, C/C++, Modbus, CANbus, OPC, TCP/IP, Linux, AWS, Azure, Docker, Kubernetes
4d
Save
Mark Applied
Hide
DevOps Engineer
White Plains or Conyers or Roanoke or Independence or Hartford or Savannah or Alexandria or Greensboro or Charleston or Missoula or Charlotte or Huntsville or Hartford or Miami or Tallahassee or Albany or Gainesville or Columbus or Boston or San Antonio or Dallas or Denver or Phoenix or San Francisco or Chicago or Nashville or Portland or Charlotte or Houston or Wilmington or Lexington or Tampa or Baltimore or Raleigh or Las Vegas or Cary or Irvine or Brookfield or Shreveport or Greenville or Van Nuys or Minneapolis or Red Bank or Jacksonville or Seattle or Sarasota or Kennesaw or Palm Beach or Towson or Sacramento or Dayton or Broomfield or Golden or Princeton or Omaha or Oklahoma City or Chesterfield or Schaumburg or Suffolk or Jupiter or Carmel or Canonsburg or Buffalo or Schaumburg or Philadelphia or Schaumburg or Sunrise or St. Louis or Los Angeles or Atlanta or Gulfport or Norwalk or South Portland or Metairie or Virginia Beach or Edina or Richmond or Southfield or Cleveland or Milwaukee or Chattanooga or Fort Worth or Rochester or Grand Forks or Detroit or Jersey City or Boise or Portland or San Ramon or Easley or Duluth or Glenville or Syracuse or West Palm Beach or Cary or Irvine or Brookfield or Shreveport or Greenville or Los Angeles or Atlanta or Orland Park or Columbia or Elmhurst or Portland or San Diego or San Ramon or Myrtle Beach or Gainesville or Hartford or Allentown or Macon or Tampa or Saint Petersburg or Irvine or Raleigh or San Ramon or Lewisville
$77k-$134k/yr RemoteFull Time
5+ YOE5+ years software development; cloud (Azure/AWS); CI/CD (Azure DevOps, GitHub Actions); scripting (Python, Bash, PowerShell); Git; strong communication; delivery track record.
Azure, AWS, Terraform, Azure Bicep, Docker, Kubernetes, Git, Azure DevOps, GitHub Actions, Python, Bash, PowerShell
1w
Save
Mark Applied
Hide
AI Engineer / Data Scientist, AI Senior Associate
New York or Raleigh or Charlotte or Chicago or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Rochester or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Los Angeles or Seattle or Albany or Stamford or Atlanta or Austin or Denver or Des Moines or Detroit or Buffalo or Florham Park or Greensboro or Hartford or Houston or Indianapolis or Grand Rapids or Irvine or Jacksonville or Kansas City or Las Vegas or Little Rock or Los Angeles or Louisville or Miami or Milwaukee or Minneapolis or Montpelier or Nashville or New Orleans or Oklahoma City or Philadelphia or Phoenix or Pittsburgh or Portland or United States
$72k-$184k/yr OnsiteFull Time
2+ YOEExperience in AI/ML, data analytics, governance or risk; Bachelor's degree; 2+ years of experience.
Python, SQL, R, TensorFlow, scikit-learn, Data Visualization
1mo
Save
Mark Applied
Hide
Software Engineer (AI/ML Interface Development)
San Diego or Nashua or Greenlawn or Durham
$92k-$157k/yr HybridFull Time
4+ YOEBS in CS/Software Eng; 4+ yrs in software dev; proficiency in Python/Java/C++; experience with AI/ML models, LLMs, vector DBs; API/microservices; CI/CD; Docker/Kubernetes; US Secret Clearance.
Docker, Kubernetes, Python, Java, C++, TensorFlow, PyTorch
3w
Save
Mark Applied
Hide
Principal Engineer, Agentic AI
Greensboro or Denver
$144k-$180k/yr OnsiteFull Time
8+ YOE8+ years software engineering; 2+ years AI/ML; Copilot Studio and Azure Foundry expertise; TypeScript, Python, C#; two more agent frameworks; agentic AI patterns; Bachelor’s in CS/AI/Engineering; Sierra AI and Power Platform governance experience.
Copilot Studio, Azure AI Foundry, Azure OpenAI Service, Prompt Flow, Semantic Kernel, LangChain, LangGraph, AutoGen, CrewAI
4d
Save
Mark Applied
Hide
Business Systems Engineer
Durham or Research Triangle Park
OnsiteFull Time
5+ YOE5+ years in technical business systems, systems integration, or enterprise software; proven ability to design, implement, and own integrations and data workflows.
NetSuite, Fiix, Ramp, Gusto, HubSpot, APIs, ERP, SQL, Python, Docker, Linux
1w
Save
Mark Applied
Hide
Chief Engineer – Artificial Intelligence (AI) Applications
Dedham or Bloomington or McLeansville or Pittsburgh or Manassas or Scottsdale
$221k-$239k/yr HybridFull Time
10+ YOEBachelor's in STEM with 10+ years in AI; or Master's with 8+ years; DoD Top Secret clearance; travel 25-35%; U.S. citizenship.
TensorFlow, PyTorch, Python, Git, GitLab, Docker, Kubernetes, Linux
2mo
Save
Mark Applied
Hide
Staff Engineer I – Simulation Analyst
Durham, North Carolina, United States
OnsiteFull Time
10+ YOEBachelor's in Mechanical or Biomedical Engineering; 10 years in nonlinear structural simulation (FEA); CAD experience; proficient in Abaqus/ANSYS/COMSOL/LS-DYNA; strong scripting and data analysis.
Abaqus, ANSYS, COMSOL, LS-DYNA, MCalibration, PolyUMod, nTop, HEEDS, Kornucopia, Minitab, Python, MATLAB, SolidWorks
4d
Save
Mark Applied
Hide
Sr. Industrial Engineer (Greensboro, NC, US, 27409)
Greensboro, North Carolina, United States
OnsiteFull Time
5+ YOEBS in Industrial/Systems Engineering; 5+ years experience; Lean; data analytics; advanced Excel/VBA; manufacturing environment.
LEAN, Excel, VBA, Python, SQL, Tableau, Spotfire
1mo
Save
Mark Applied
Hide
Sr. Engineer, Machine Learning (Durham, NC, US, 27712)
Durham, North Carolina, United States
$148k/yr OnsiteFull Time
2+ YOEBS with 2 years of experience or MS/PhD with capstone/thesis in CS or Engineering; travel up to 25%; no immigration sponsorship.
Python, C++, C#, R, MATLAB, JMP, CUDA, Linux, Git, OpenCV, TensorFlow, PyTorch, Streamlit, Dash, Pandas, SQL, Power BI, Blazor, HALCON, CUDA-based acceleration
1w
Save
Mark Applied
Hide
Senior Clinical Programmer
Durham, North Carolina, United States
$88k-$221k/yr OnsiteFull Time
Develop and validate KRIs and QTLs in CluePoints CM; RBQM; strong SAS and analytics; collaboration with cross-functional teams.
SAS, SQL, Python, R, Spotfire, CluePoints CM
1mo
Save
Mark Applied
Hide
Software Engineering Manager
Aliso Viejo or Fort Myers or Durham or Carlsbad
RemoteFull Time
5+ YOE3+ Mgmt5+ years leading application development; 3+ years managing engineers; healthcare/clinical system experience preferred.
.NET, Python, Microsoft SQL Server, Vue.js, React, Azure, EHR, FHIR, HL7, APIs
1w
Save
Mark Applied
Hide
Dir, Epidemiology Pipeline (TA - Virology)
Morrisville, North Carolina, United States
OnsiteFull Time
Graduate degree in Epidemiology, Statistics, or Public Health; Virology trials expertise; knowledge of study designs; basic SAS/R/Python; strong communication and leadership.
SAS, R, Python
1mo
Save
Mark Applied
Hide
Client Services Consultant
Reston or Promontory or Austin or Plano or Burlington or Princeton or Durham
$107k-$190k/yr OnsiteFull Time
12+ YOEKubernetes SRE with deep systems engineering, customer advocacy, IaC, observability, and strong scripting skills.
Kubernetes, vSphere, Terraform, Helm, GitOps (ArgoCD or Flux), Prometheus, Grafana, Jaeger, OpenTelemetry, Bash, Python
2mo
Save
Mark Applied
Hide
Actuary, Annuity Model Development (Radnor, PA, US)
Radnor or Charlotte or Fort Wayne or Greensboro or Hartford or Omaha
$109k-$196k/yr HybridFull Time
7+ YOEActuary with 7-10 years actuarial modeling/valuation, AXIS experience, extensive annuity product knowledge, and strong regulatory/GAAP/Tax understanding; excellent communication; FSA preferred or ASA required.
AXIS, R, Python, SQL, Excel VBA, Tableau
HiringCafe market data
Senior Python Developer Jobs market signals in Danville, VA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
92
Hiring companies
31
Fresh sample
59% new in 30d
Salary visibility
54% show pay
Companies appearing in this market
Hewlett Packard EnterpriseAnalog DevicesFidelity InvestmentsLabcorpNutanixNVIDIAAstraZenecaNubank
Work location mix in visible results
Hybrid: 41Onsite: 22Remote: 5