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Senior Python Developer Jobs in Greencastle, PA, US
28 senior python developer jobs from 18 companies hiring in Greencastle, PA, US.
2w
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Senior Software Developer
Richmond or Baltimore or Nashville or Mechanicsburg or Raleigh
$105k-$145k/yr HybridFull Time
5+ YOESenior software developer with 5+ years of experience in full-stack design and geospatial applications.
SQL, C#, Java, Python, HTML, CSS, JavaScript, ASP.Net Core, Angular, React, Vue.js, Esri software
6d
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Senior Application Engineer
Vienna or Winchester or Pensacola
$115k-$180k/yr HybridFull Time
5+ YOEBachelor’s degree in Computer Science, Information Systems, or related field; 5–7 years in application/software development; Azure cloud experience; proficient in SQL, Python, JavaScript; strong communication and problem-solving.
SQL, Python, JavaScript, HTML/CSS, Azure, Azure Compute, Azure Storage, Azure Data & Analytics, Git
2w
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Senior Software Engineer - Full-Stack
Carlsbad or Germantown or United States
$136k-$253k/yr RemoteFull Time
5+ YOE5+ years web app development with React/Spring Boot/Python/Go; cloud experience (AWS/Azure); microservices; BS in CS/Computer Engineering or related; US citizenship; eligible for Secret Clearance; up to 10% travel.
React, Spring Boot, Python, Go, AWS, Azure, Cloud, Microservices, Redis, Elasticsearch, InfluxDB, Next.js, TanStack, Docker, Kubernetes, GitHub Actions, Ansible, ArgoCD
4d
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Senior Network Systems Engineer
East Palo Alto or Clarksburg or Arlington
$140k-$185k/yr HybridFull Time
5+ YOE5+ years hands-on network engineering; strong L2/L3, Linux, VPN, AWS; travel ~50%; collaborate across teams.
systemd-networkd, Netplan, iptables, StrongSwan, WireGuard, Ansible, Terraform, Bash, Python, Go, Grafana, Telegraf, AWS, EC2, VPC, Transit Gateway, S3, VPN
3w
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Sr. Innovation Software Engineer
Minnetonka or Austin or Chicago or Easton or Dallas or Detroit or Hagerstown or Atlanta or Houston or Akron or Birmingham or Charlotte or Indianapolis or Pittsburgh or Cincinnati or Cleveland
$77k-$154k/yr OnsiteFull Time
8+ YOESenior software engineer with full-stack, AI-enabled solution delivery; 8-12 years of experience.
Java, Python, TypeScript/JavaScript, Vertex AI, Google Cloud
1d
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CUAS SW Engineer
United States or Summit Point
$88k-$155k/yr RemoteFull Time
5+ YOE5+ years' software engineering experience; Bachelor's in CS/engineering/math or related field or equivalent; active Secret clearance; Java; APIs; AI/ML; Python/C++; Docker; Git; Agile tooling.
Java, APIs, Ansible, Docker, React, Git, CMake, Confluence, JIRA, Python, C++, AI/ML
1d
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Senior Systems Engineer (Production Support)
Frederick, Maryland, United States
RemoteFull Time
8+ YOE8+ years of experience in systems engineering, production environments; strong cloud, Linux/Windows, scripting, automation, and security knowledge.
AWS, Azure, Linux, Windows, Python, Bash, PowerShell, Ansible, Puppet, Chef, SaltStack, CloudFormation, DynamoDB, RDS, SQL, Git, GitHub Actions, CodeBuild, CodeDeploy, CloudWatch, S3, Step Functions, Batch Jobs, DynaTrace, Science Logic
1mo
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Principal Engineer - Controls
Hagerstown, Maryland, United States
$92k-$148k/yr OnsiteFull Time
5+ YOEBachelor's degree in mechanical/electrical engineering with 5+ years of related experience; strong vehicle controls experience; CAN bus; MATLAB/Simulink; AMEsim; dSPACE; Autosar; C/C++; Python.
MATLAB/Simulink, AMEsim, dSPACE, Vector tools, Autosar, C/C++, Python, ADAMS
5h
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Embedded Software Engineer IV
Germantown, Maryland, United States
$91k-$130k/yr HybridFull Time
5+ YOEBachelor’s degree in computer engineering, electrical engineering, software engineering, computer science, or related field with 5+ years of embedded C/C++ experience; Linux/RTOS; scripting; device drivers; cybersecurity awareness; agile/SDLC.
C, C++, Bash, Python, Linux, QNX, FreeRTOS, CI/CD
4w
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Site Reliability Engineer
Frederick, Maryland, United States
OnsiteFull Time
6+ YOE6+ years in DevOps/SRE with monitoring; 4+ years Linux; IaC on cloud; CI/CD; Python/Bash; AI/DevOps; containers; security basics.
Prometheus, Grafana, ELK, Splunk, Terraform, Ansible, Chef, Puppet, Jenkins, GitHub Actions, Docker, Kubernetes, Python, Bash, PowerShell, Node.js, Java, .NET Core, SQL, NoSQL
1w
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Palantir AIP & Foundry Lead Engineer
Camp Hill, Pennsylvania, United States
RemoteFull Time
10+ YOE10 years of experience with Palantir Foundry/AIP, Python/SQL/PySpark/Typescript; data pipelines; healthcare domain experience preferred.
Python, SQL, PySpark, Typescript
2mo
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Generative AI Cloud Operations Engineer - Evinova
Gaithersburg, Maryland, United States
$135k-$202k/yr HybridFull Time
2+ YOEHS Diploma or GED; 2+ years deploying GenAI agents in production; strong Python/TypeScript; AWS; Docker/Kubernetes; LangChain/LangGraph/ADK/Strands; production ML deployment experience; collaborative and communicative.
Python, TypeScript, AWS, Docker, Kubernetes, LangChain, LangGraph, LlamaIndex, Google ADK, Langfuse, Pinecone, Weaviate, Arize Phoenix, Grafana, Prometheus, Xray
1mo
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Data Engineer – NAVSUP OIS - Onsite
Mechanicsburg or Yorktown
$130k-$155k/yr OnsiteFull Time
10+ YOE10+ years of data engineering experience; TS clearance; US citizenship; AWS GovCloud; ETL; SQL/NoSQL; data warehousing; cloud data platforms.
AWS GovCloud, AWS RDS, PostgreSQL, MySQL, Oracle, Pentaho, Apache Hadoop, Apache Spark, Kafka, RedShift, MicroStrategy, Erwin Data Modeler, Python, Java, Scala, Go
1mo
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Data Engineer – NAVSUP OIS - Onsite
Mechanicsburg or Yorktown
$130k-$155k/yr OnsiteFull Time
General Dynamics Information TechnologyNYSE: GD: Provides mission-critical IT services to government and defense organizations.
10+ YOE10+ years of related experience; Top Secret clearance; US citizenship; AWS GovCloud; SQL/ETL; data warehousing; strong collaboration skills.
AWS GovCloud, RDS, PostgreSQL, MySQL, Oracle, SQL, Python, Java, Scala, Go, Spark, Kafka, Hadoop, RedShift, Liquibase, GitLab, CI/CD, ETL, Pentaho, Erwin Data Modeler
2mo
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Modeling and Simulation HPC Back End Software Developer
Frederick, Maryland, United States
$94k-$198k/yr OnsiteFull Time
5+ YOETS/SCI with polygraph; BS in Computer Science, Modeling and Simulations or related field; 5+ years’ experience; Python, C Shell, Slurm; Unix/HPC experience; strong communication; ability to brief senior leaders.
Python, C Shell, Slurm, UNIX, High-Performance Computing
1mo
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Staff Mission Assurance Engineer
Sykesville, Maryland, United States
$169k-$254k/yr OnsiteFull Time
12+ YOEBachelor’s in a STEM field with 12+ years quality experience or Master’s with 10+ years; requires US citizenship and ability to obtain Secret DoD clearance.
Java, C++, C#, Ada, VHDL, Python, MATLAB, JIRA, Version control
1mo
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AI Research Computing Infrastructure Engineer
Frederick, Maryland, United States
$124k-$207k/yr OnsiteFull Time
8+ YOEBachelor’s degree or 4 years experience; 8+ years related experience; Linux systems engineering; container orchestration; scripting; IaC tooling; performance tuning; security clearance ability.
Kubernetes, Nomad, Run:AI, Python, Bash, Go, Terraform, Ansible, Packer, Pytorch, Ray, Airflow, Dagster, Kubeflow, Prefect, Dagster, Kubeflow, MLFlow
2w
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Sr. Research Associate, Mass Spectrometry (#1901)
Frederick, Maryland, United States
$65k-$107k/yr OnsiteFull Time
6+ YOE6+ years with BS or 4+ with MS; MS instruments (LC-MS/MS, MALDI-TOF); proteomics/metabolomics experience; sample prep; data analysis with Proteome Discoverer, Compound Discoverer, MassHunter, Skyline, MaxQuant, FragPipe, MS-Dial; programming (R, Python) a plus; strong communication and teamwork; U.S. citizen with ability to obtain interim secret th...
Mass spectrometry instruments, LC-MS/MS, MALDI-TOF, Proteomics software, R, Python, Proteome Discoverer, Compound Discoverer, MassHunter, Skyline, MaxQuant, FragPipe, MS-Dial
3w
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Technical Product Manager
Frederick, Maryland, United States
$120k-$145k/yr HybridFull Time
7+ YOE7+ years software development with client-facing and leadership experience; full-stack delivery; strong communication and architectural skills.
PHP/Laravel, Node.js/TypeScript, .NET, Python, React, Databases, Cloud platforms
HiringCafe market data
Senior Python Developer Jobs market signals in Greencastle, PA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
28
Hiring companies
18
Fresh sample
56% new in 30d
Salary visibility
81% show pay
Companies appearing in this market
ForterraSyms Strategic GroupGeneral Dynamics Information TechnologyNavy Federal Credit UnionViasatAstraZenecaAxle InformaticsBattelle National Biodefense Institute
Work location mix in visible results
Onsite: 12Hybrid: 8Remote: 7