Explore 2 senior python programmer jobs from 2 hiring companies in Smith Mills, MA, US. Filter by remote, salary, experience, and company, then open any listing to apply.

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Senior Python Programmer

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Senior Python Programmer Jobs

CD PROJEKT RED

Compass Therapeutics

Hybrid

Company Description:To create revolutionary, story-driven RPGs which go straight to the hearts of gamers — this is our mission. Want to dive deeper into our company’s culture? Explore our social media and check out our&#xa0;<a href="https://www.youtube.com/CDPRED" rel="noopener noreferrer">YouTube channel</a>&#xa0;where we share behind-the-scenes insights and stories direct from our team members!Job Description:CD PROJEKT RED seeks an experienced Senior Tools Programmer to support efforts in enhancing development workflows for Cyberpunk 2, the next mainline Cyberpunk 2077 game. This role requires advanced expertise in creating robust, user-focused tools and proactive engagement in driving innovation across our engineering processes.Daily Responsibilities<ul><li>Help drive the design and implementation of high-quality, maintainable C++ tools and workflows, primarily for Unreal Engine.</li><li>Collaborate closely with cross-disciplinary teams to understand complex needs, propose effective solutions, and champion tools development efforts.</li><li>Independently manage the full lifecycle of tool initiatives, from ideation and prioritization, to deployment and ongoing support.</li><li>Proactively provide ad hoc tools support, effectively balancing immediate needs against broader development priorities without constant oversight.</li><li>Evangelize tools best practices, advocating their strategic importance to productivity and quality across the organization.</li><li>Objectively evaluate the impact of tools and workflows on project productivity to inform prioritization decisions.</li><li>Mentor and support junior and mid-level engineers, enhancing team capabilities.</li></ul>Qualifications:<ul><li>Extensive experience writing production-level C++ code, with significant, demonstrable contributions to complex, large-scale codebases on collaborative projects.</li><li>Experience driving projects through their full lifecycle, from concept to deployment and maintenance.</li><li>Ability to articulate technical concepts, discuss trade-offs, and advocate for quality standards.</li><li>Experience with planning work according to priorities, risks, and the need to deliver value incrementally.</li></ul>Nice to have:​​​​​​ 
(please note these skills are not required for to apply for the position)<ul><li>Extensive experience with Unreal Engine or similar AAA game engines.</li><li>Proficiency in UI/UX design, specifically with Slate, Editor Utility Widgets, or comparable frameworks.</li><li>Previous mentorship or technical leadership experience in a game development context.</li><li>Experience with a scripting language or system, such as Blueprint, Python, MEL.</li></ul>Additional Information:The application window for this position will close by 10/30/2026.This job can be hybrid/in-office or fully remote. 
 
Remote roles in the US are only available to candidates that reside in the following states:&#xa0;California, Colorado, Connecticut, Florida, Illinois, Kentucky, Maryland, Massachusetts, Minnesota, Nevada, New Hampshire, New Jersey, New York, North Carolina, Ohio, Oregon, Pennsylvania, Rhode Island, Tennessee, Texas, Washington, Wisconsin.Health &amp; Well-Being<ul><li>Company-paid medical healthcare (dental, vision, and mental).</li><li>Free mental health support, including access to counseling, psychiatric care, and a variety of well-being webinars.</li><li>Paid leave — 26 days of vacation, 10 sick days, &amp; 12 calendar holidays per year.</li><li>401K with employer matching.</li><li>Lifestyle Spending Account (LSA) – $100 per month to use towards fitness, wellness, internet, home office equipment, learning, streaming services, and more.</li><li>Menstrual leave — employees who menstruate can take one extra day off when experiencing period pain.</li><li>RED Parents Network — support for working parents.</li><li>Flexible working hours.</li></ul>Perks &amp; Professional Growth<ul><li>Trainings, lectures, and courses — internal workshops, knowledge-sharing initiatives, online tutorials, and e-learning classes are all available.</li><li>A welcome pack filled with goodies — to help you feel right at home once you join the team.</li></ul>Life in the Office<ul><li>Dog-friendly office — bring your pooch with you and look after them while working! There’s always a furry friend or two to meet.</li><li>Truly international working environment — a chance to meet and work with a diverse selection of people from all around the world.</li><li>No dress-code — we like to keep it casual.</li></ul>This position is a new role.Estimated pay range for this position:&#xa0;$118,800 -&#xa0;$217,800 USD annually.&#xa0;At CD PROJEKT RED compensation for our roles in North America are determined based on competitive market data, geographic location, and individual factors tied to business needs. The base pay range is subject to change and may be modified in the future. Final offers are&#xa0;dependent on job-related factors like experience, qualifications, and location.If you've observed any irregularities (i.e. legal or ethical violations) in our recruitment process, please click&#xa0;<a href="https://www.cdprojekt.com/en/esg/share-your-opinion/" rel="noopener noreferrer">here</a>&#xa0;to report them anonymously.

Senior Tools Programmer

Extensive production C++ experience; full lifecycle tool development; strong communication; prioritize and deliver value.

Compass Therapeutics, Inc. was founded in 2014 and is headquartered in Boston, MA. We are an oncology-focused biopharmaceutical company discovering and developing proprietary antibody-based therapeutics to treat multiple diseases. Our robust pipeline currently includes four clinical assets spanning all phases of development, with novel mechanisms of action, and first-in-class or best-in-class potential across multiple tumor types. Our lead clinical-stage asset, tovecimig, has completed a randomized late-stage biliary tract cancer study and we are preparing for a BLA submission. We are now at an exciting inflection point as we scale our organization to support our first product launch. This is a unique and pivotal moment to join us and help make a meaningful impact on patients’ lives. For more information, visit <a href="http://www.compasstherapeutics.com">www.compasstherapeutics.com</a>.
Our Clinical team is seeking a hands‑on strategic Senior Manager, Clinical Statistical Programmer, reporting to our Director of Biostatistics. The ideal candidate will have a proven track record of successfully leading clinical safety analysis and programming across multiple programs, in a fast-paced environment. This role combines deep technical expertise in SAS and R with ownership of ongoing safety maintenance and leadership in modern data visualization platforms. The individual will support active trials, long‑term safety monitoring, and the integration of complex data streams, including translational and real-world data (RWD).
This position works onsite 4 days/week in the Brighton, MA office.
&nbsp;Responsibilities
<ul>
<li>Lead Statistical Programming processes, support Clinical strategies, and manage the execution of programming activities across all of our clinical-stage antibody assets and drug candidates in support of commercialization.</li>
<li>Ensure that Compass Clinical department goals are on track to reach milestones within established timelines, while adhering to quality standards and applicable regulations.</li>
<li>Provide continuous programming support for active studies, ensuring safety outputs (AEs, SAEs, Labs, Vitals) remain current, validated, and inspection readiness.</li>
<li>Lead the production of recurring safety outputs and data packages for Data Safety Monitoring Boards and internal safety review committees.</li>
<li>Oversee medical coding outputs (MedDRA, WHO Drug) and perform clinical-to-safety database SAE reconciliation to ensure data integrity.</li>
<li>Lead the development of interactive dashboards and exploratory tools using platforms such as Spotfire, R Shiny, or R-based frameworks.</li>
<li>Create and maintain customized patient profiles to facilitate efficient medical monitor and safety physician reviews.</li>
<li>Partner with Biostatistics and Clinical Safety teams to translate clinical questions into actionable visual analytics and early trend identification.</li>
<li>Build and maintain reusable SAS/R macros and standard templates to improve programming efficiency and consistency across the portfolio.</li>
<li>Develop and execute periodic data quality checks to identify anomalies, trends, or emerging issues early in the study lifecycle.</li>
<li>Design and maintain complex derived variables and analysis-ready datasets to support evolving reporting requirements.</li>
<li>Ensure all programming documentation and datasets meet high standards for regulatory submissions and audit readiness.</li>
<li>Support the roadmap for future real-world data (RWD) and safety data streams.</li>
</ul>
Qualifications
<ul>
<li>Bachelor’s degree in Statistics, Biostatistics, Computer Science, Mathematics, or a related field, and advanced degree is preferred.</li>
<li>8+ years of clinical statistical programming experience within the Pharmaceutical, Biotech, or CRO industry.</li>
<li>Advanced proficiency in SAS (SDTM/ADaM) and R/Python for clinical trial analysis and data visualization.</li>
<li>In-depth knowledge and proven expertise of clinical safety data structures, medical coding standards, and SAE workflows.</li>
<li>Demonstrated experience leading implementation and maintaining data visualization platforms (e.g., Spotfire, R Shiny) in a clinical environment.</li>
<li>Preferred experience handling&nbsp;translational data (e.g., biomarkers, genomics, or PK/PD integration) and its associated complexities.</li>
<li>Prior experience acting as a programming lead or senior technical contributor with oversight of FTE or vendor-provided deliverables is ideal.</li>
<li>Exposure to post-marketing safety data or the analysis of real-world evidence (RWE) is preferred.</li>
<li>Experience identifying critical risks, ability to provide appropriate solutions and mitigate risks; strong work principles and ethical standards are required.</li>
<li>Strong attention to detail with the ability to balance multiple project objectives in a fast-paced, collaborative work environment.</li>
<li>Excellent written and verbal communication skills, with the ability to clearly articulate complex data to diverse audiences.</li>
</ul><div class="content-pay-transparency"><div class="pay-input"><div class="title">Base Salary Range in Job Post</div><div class="pay-range">$140,000&mdash;$198,000 USD</div></div></div><div class="content-conclusion">Our mission is to develop next generation antibodies into transformative cancer therapies that improve patients’ lives. We built our core values from the employees up and each and every one of us is essential to achieving our mission. We are mission-focused, share a passion for science and creativity that help us innovate in all that we do. Our unique culture and community promotes authenticity, diversity of thought, and collaborative teamwork. &nbsp;
Compass provides employees with a comprehensive and market-leading compensation and benefits package. Our compensation package includes a base salary, discretionary bonus, and meaningful equity participation for every employee. Our innovative benefits offerings support holistic employee health and wellness - from subsidized medical, dental and vision premiums to health reimbursement arrangement, flexible spending accounts, gym membership, employee assistance program, life insurance, and much more. We also offer 401(k) and Roth 401(k) programs with a 6% company match. Additional benefits include company parking, commuter reimbursement, and substantial vacation and leave policies, including summer Fridays, and a winter shut down week.
Beyond traditional benefits, we invest in the growth and development of our teams and individuals through programs such as company-wide training, tuition and training reimbursement, recognition awards, and comprehensive performance management. With our Compass Culture Committee, we grow and preserve our culture through: events that build camaraderie and celebrate wins both large and small, diverse employee-driven initiatives, participation in charitable causes, and other programs that align with our values.</div>

Senior Manager, Clinical Statistical Programmer

8+ years clinical statistical programming experience; SAS/ R; knowledge of safety data and SAE workflows; leadership in data visualization.

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Senior Python Programmer Jobs in Smith Mills, MA, US

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