At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we’re in. Are you?

About the Role:

We’re looking for an Executive Director, Computational Biology on the Biologics Research team to help us expand what’s possible for patients with serious diseases. Our group develops cutting-edge AI-driven protein design and optimization methods, works in close collaboration with experimental teams to apply them in the discovery of next-generation biotherapeutics, and analyzes the resulting data to feed back into models and to guide subsequent rounds of design and engineering. We are actively engineering therapeutic proteins with a variety of functions, from binders to enzymes to viral vectors, with similarly wide-ranging computational design tasks and experimental screening capabilities. Reporting to the Vice President of Research, you’ll lead and expand a team that is pushing the frontiers of modeling, design, and analysis in many corners of the protein universe, collaborating seamlessly with innovative experimental scientists to create translation-ready drug candidates.

What You'll Do:

In this role, you’ll have the opportunity to develop and expand advanced computational biology capabilities and support diverse biologics discovery programs. You’ll also:

Guide research strategy for AI-based protein design and data science through the lens of biotherapeutic research.
Lead, mentor, and grow two outstanding teams of computational biologists (protein design and data science).
Coordinate collaborations with experimental teams responsible for drug discovery projects and enabling research platforms.
Guide continued integration of computation and experiment as we scale our use of laboratory automation and adopt fit-for-purpose agentic AI-enabled workflows.
Partner with adjacent computational research groups, the Information Technology Department, and other key stakeholders to develop and implement overall corporate strategy for advanced computing technologies.

Who You Are:

You have a PhD in Computer Science, Statistics, Mathematics, or a related discipline along with 10 years of experience in computational biology.

You are or you also have:

Deep expertise in computational protein design.
Proven ability to lead and inspire a team of computational biologists while fostering productive collaborations with experimental scientists.
Strong track record of scientific creativity and innovation, pushing the envelope in relevant areas.
Thorough understanding of, and hands-on experience with, state-of-the-art deep learning models and methods for protein design and predictive analysis.
Demonstrated skills and experience in the analysis, interpretation, and visualization of diverse data relevant to protein design and engineering; facility with next-generation sequencing data helpful.
Ability to partner with Information Technology to buildout and maintain computational and data infrastructure for research and development.
Talent for balancing long-term strategic vision with hands-on execution of technical research.

Where You’ll Work

This is a fully remote role. It can be performed effectively from anywhere while staying connected to your Insmed team and community. Occasional travel for team meetings or events will be expected.

Travel Requirements

This role requires occasional global travel (approximately <10%).

Pay Range:

$255,000.00-347,500.00 Annual

Life at Insmed

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. 

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

For New York City Residents:

To assist in identifying candidates with qualifications matching those required and/or preferred for this role, Insmed uses an Automated Employment Decision Tool (“AEDT”) that employs artificial intelligence to analyze and score information provided in resumes and application materials including, but not limited to, skills, work experience, education, and job-related qualifications. The AEDT does not make final hiring decisions and all final hiring decisions are subject to human oversight and/or review.

If you are an applicant for this role and a New York City resident, you have the right to request:

A reasonable accommodation, if one is available under applicable law, by emailing [email protected]; and/or
An alternative selection process by emailing [email protected].
Information about the type of data collected, the source of that data, and data retention practices related to the AEDT by emailing us at [email protected].