Posted 3w ago

Principal Medicinal Chemist

@ Deep Origin
Shenzhen, Guangdong Province, China
RemoteFull Time
Responsibilities:Leading strategies, Designing compounds, Analyzing SAR
Requirements Summary:PhD in Organic Chemistry or related field with 3-8 years industry experience in medicinal chemistry; track record in hit-to-lead/lead optimization; expertise in synthetic organic chemistry and drug design; experience with external CROs and cross-functional collaboration; strong English communication; remote international collaboration.
Technical Tools Mentioned:Structure-based design, Ligand-based design, Computational modeling, Cheminformatics tools
Save
Mark Applied
Hide Job
Report & Hide
Job Description

About Deep Origin

Deep Origin is a biotechnology company building an operating system for science that transforms how life science research is conducted. Our AI-powered platforms simulate biology, streamline R&D workflows, and enable scientists to model complex biological systems at scale.

As part of strategic government-backed initiatives and the expansion of our AI-driven simulation infrastructure, we are scaling our capabilities in whole-human modeling and predictive toxicology. Exceptional modeling talent is a critical lever in accelerating our mission to reduce disease and extend human healthspan.


About the Role

We are seeking a Principal Medicinal Chemist to lead and advance small-molecule drug discovery programs from early hit identification through development candidate selection. This is a senior, hands-on scientific leadership role requiring deep expertise in medicinal chemistry, strategic thinking, and cross-functional collaboration.

This position calls for a highly creative and experienced chemist who can independently design and execute medicinal chemistry strategies while contributing to the integration of computational and AI-driven approaches into drug discovery workflows. The ideal candidate will combine strong technical depth with the ability to guide internal teams and external partners toward impactful outcomes.