Key Responsibilities
- Design, plan, and perform in-vivo experiments to evaluate the efficacy and safety of small molecule/biologics drug candidates.
- Analyse and interpret complex biological data to Hit/Lead selection and optimization.
- Develop and validate in-vivo/in-vitro model systems for evaluation of NCE’s.
- Collaborate with multidisciplinary teams including synthetic chemists, bioinformatics, pharmacokinetic scientist, molecular biologist and external CROs to drive project goals.
- Utilize statistical tools to support data analysis and compound optimization.
- Prepare detailed reports, technical summaries, and presentations.
- Stay updated with current scientific literature and advancements in drug discovery methodologies and technologies.
- Contribute to the preparation of scientific publications, patent applications, and regulatory documentation as needed.
Qualifications
Knowledge/Skills/Abilities
- PhD freshers or 1-2 years or master’s with 3-8 years of industry experience in immuno-oncology, pharmacology, biology, or a related field.
- Proven experience in drug discovery and development with small molecules/biologics.
- Experience with in-vivo pharmacology studies in the disease area of oncology.
- Strong knowledge of biochemical, cell-based, and analytical assay techniques.
- Excellent problem-solving, and organizational skills.
- Strong communication skills, both written and verbal.
- Expertise in designing and executing experiments for drug efficacy.
- Ability to interpret complex scientific data to guide drug optimization.
- Proficiency in establishing and validating experimental models.
- Collaborative mindset with the ability to work effectively in multidisciplinary teams.
- Commitment to scientific rigor, innovation, and continuous learning.
Required Technical Skills
In-vivo Skills
- Expertise in animal handling includes sampling and dosing by different routes (IP, IV, PO)
- Plan and execute mouse tumor models like Xenograft
- Expertise in tissue processing and in-vitro/ex-vivo assay techniques
Data Analysis/Documentation
- GraphPad Prism or equivalent statistical software
- Data interpretation and report preparation
- Contribute to internal research updates, publications, and regulatory documentation.
Preferred Skills
- Experience in immuno-oncology models
- Knowledge of tumor microenvironment biology
- Experience with biomarker analysis
About Company
The Human Resources team partners with all aspects of the organization, driving success through the effective and innovative management of people for both current and future business needs.
Key roles that the Human Resources team performs:
Executive Role: Specialists in all aspects of people management. High-level input at strategic level into all key business decisions.
Audit Role: Ensures all areas of the organization are compliant with legal requirements AND best practice employment policies and procedures.
Facilitator Role: Close partnership to support, advise and extend the ability of all areas of the organization to meet their objectives through implementation of highly effective employment practices in areas such as Talent Acquisition, Learning and Development, Reward systems, Performance Management, Health and Wellbeing.
Consultancy Role: Provide expert advice to the organization and it’s managers on any aspect of workforce management and employee relations and performance.
Service Role: Ensure the organization is fully aware of and is equipped to deal with developments impacting employment matters, such as changes in legislation, changes in the characteristics of the labor market.