Associate Director, Translational Medicine and Data Science

Who we are:

At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X.

The impact you will make:

Agios Pharmaceuticals is searching for a dynamic AD, Translational Medicine and Data Science to join our growing team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The AD, Translational Medicine and Data Science will be responsible for and accountable for Translational Medicine and biomarker objectives and deliverables for Agios’ clinical programs. This is a critical strategic role that bridges the science and technical aspects of biomarker strategy with the operational aspects for the execution in clinical studies.

What you will do:

• Lead the development of the translational biomarker strategy for development program(s), incorporating the latest research findings and leveraging novel technologies
• Oversee implementation and execution of clinical biomarkers for patient stratification, enrichment and identification, pharmacodynamics, and demonstration of mechanism of action to support clinical development. 
• Partner closely with Clinical Operations, Biostats, Data management, and Data Science to ensure clinical sample collection, analyses and data acquisition are valid and compliant.
• Direct and oversee the outsourcing and validation of clinically applicable biomarker assays. 
• Generate/review biomarker data and summary of study findings and contribute to clinical documents such as protocols, investigator brochures and regulatory submissions.
• Drive the publication of Translational Medicine data in high-quality scientific, technical or medical journals.
• Ensure effective, cross functional interactions and collaborations across the different functional areas that relate to Biomarker discovery and development.

What you bring:

• PhD or equivalent in biology, genomics or relevant biological fields
• 5+ years of clinical biomarker experience (industry experience preferred)
• Good understanding and experience across technology platforms (e.g. Next-Gen Sequencing, epigenetic and expression profiling, IHC, immunoassays, etc.)
• Familiarity with clinical trial operations and logistics for biomarker specimens
• Detail oriented, with excellent organizational skills
• Proven critical reasoning skills including the identification and resolution of complex problems
• Effective communication and interpersonal skills
• Proven ability to work independently in a fast-paced environment and deliver in a timely manner

Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening!

Work Location:

Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description..

What we will give you:

• Deliberate Development. Your professional growth as one of our top priorities.
• Flexibility.  We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.
• Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website.
• Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance.
• The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
• Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
• Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
• Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.