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Ai Python Software Engineer Jobs in Lancaster, PA, US
70 ai python software engineer jobs from 22 companies hiring in Lancaster, PA, US.
2mo
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AI Platform Engineer, Python - Lead Software Engineer
Wilmington, Delaware, United States
$152k-$215k/yr OnsiteFull Time
5+ YOE5+ years software engineering; Python; DevOps; CI/CD; cloud; AI feature development and security.
Python, DevOps, CI/CD, cloud platforms, automation, testing, Terraform
2w
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AI Platform Engineer, Python - Principal Software Engineer
Wilmington or Jersey City
$204k-$285k/yr OnsiteFull Time
7+ YOE7+ years software engineering, cloud DevOps, Python expertise, secure production code delivery.
Python, Terraform
2w
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Adversarial AI Software Engineer
Colorado Springs or Dallas or Eagan or King of Prussia or Moorestown or Orlando
HybridFull Time
Experienced software engineer with GitLab, Docker/Podman, Kubernetes/OpenShift, IaC (Ansible/Helm); Python; AI/ML frameworks; secure DevOps practices; able to work across classified/unclassified environments.
GitLab, Docker, Podman, Kubernetes, OpenShift, Ansible, Helm, Python, PyTorch, TensorFlow, LangChain, LangGraph, LangFuse, OpenTelemetry
4d
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AI Engineer
Auburn or Aberdeen
OnsiteFull Time
5+ YOEBachelor’s degree in engineering, computer science, or related field; 5+ years AI experience; agentic AI; cloud platforms; programming in Go/C++/Python; US citizenship and ability to obtain clearance; willing to travel.
Go, C++, Python, JetBrains, VSCode, REST, GraphQL
2mo
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Sr. Software Engineer (AI Solutions)
Owings Mills, Maryland, United States
$121k-$206k/yr HybridFull Time
5+ YOEBachelor’s in CS or related field with 5+ years of progressive experience; proficient in Java or Python, Node/TypeScript; cloud-native architectures (AWS/Azure); containerized microservices; agent frameworks; strong testing and API design.
Java, Python, Node, TypeScript, AWS, Azure, microservices, containerization, agent frameworks
2w
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Manager, Engineering (Software & AI)
Urbandale or Wilmington or Minneapolis or Chicago or Wacker Drive
$127k-$165k/yr OnsiteFull Time
3+ YOE3+ Mgmt3–10 years in software and/or data engineering with proven leadership; Databricks and modern data platforms; AI/ML; Python; enterprise AI integration; strong communication with senior stakeholders.
Python, Databricks, LLMs, Generative AI
3w
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Sr. Innovation Software Engineer
Minnetonka or Austin or Chicago or Easton or Dallas or Detroit or Hagerstown or Atlanta or Houston or Akron or Birmingham or Charlotte or Indianapolis or Pittsburgh or Cincinnati or Cleveland
$77k-$154k/yr OnsiteFull Time
8+ YOESenior software engineer with full-stack, AI-enabled solution delivery; 8-12 years of experience.
Java, Python, TypeScript/JavaScript, Vertex AI, Google Cloud
1w
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Software Engineer II - AI Solutions
King of Prussia, Pennsylvania, United States
HybridFull Time
3+ YOE3+ years AI/ML or backend development; Python/Java/JavaScript; healthcare data standards; cloud platforms; CI/CD; strong problem-solving and communication.
Python, Java, JavaScript, TypeScript, PyTorch, TensorFlow, LangChain, Keras, SQL, NoSQL, AWS, Azure, Google Cloud, Oracle Cloud, Palantir, Databricks, Docker, Kubernetes, Grafana, Datadog, Langfuse, CI/CD, DevOps, Microservices, Observability
4d
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Engineer 3, Agentic AI
Philadelphia or West Chester
OnsiteFull Time
5+ YOE5-7 years building agentic AI systems in production; hands-on with ADK and Python; experience with Gemini Enterprise; AI in SDLC; strong prompt engineering; production-grade software.
Agent Development Kit (ADK), Python, Gemini Enterprise
1w
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AI Documentation Engineer (Exton, PA, US)
Exton, Pennsylvania, United States
HybridFull Time
Python or TypeScript/JavaScript experience; hands-on AI/ML or LLM work; familiarity with structured content (DITA XML); experience with content/data pipelines and AI-ready documentation.
Python, TypeScript, JavaScript, LLM APIs, DITA XML, Git, Azure DevOps
4w
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Software Engineer (Mid-level)
Springfield, Pennsylvania, United States
HybridFull Time
3+ YOE3-5 years professional software development; cross-stack ability; strong collaboration; able to leverage AI tools; portfolio
.NET Core, Node.js, Python, React, Next.js, TypeScript, Azure, SQL Server, Microservices, Functions, Lambdas, CI/CD, Unit Testing, Automated Testing
1w
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103Q - Lead Software Development Engineer - Flex Location
Parsippany or Atlanta or Mahwah or Louisville or Timonium
$121k-$225k/yr HybridFull Time
Lead AI engineer with hands-on software development, experience with Generative AI, GitHub Copilot, and DX tooling; strong Python/Java/C# background; familiar with large-scale enterprise environments.
Python, Java, C#, GitHub Copilot, Microsoft Copilot Studio, Power Platform, LLMs, Embeddings, RAG
2mo
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Staff AI/ML Engineer (Large Language Model) (TS/SCI) {S}
King of Prussia, Pennsylvania, United States
OnsiteFull Time
8+ YOELead multidisciplinary AI/ML efforts; 8+ years in software/data roles with LLM experience; TS/SCI clearance; strong Python and ML libraries; experience with LLM deployment and RAG.
Python, NumPy, Pandas, Polars, scikit-learn, Git, GitLab, Bitbucket, Weaviate, Pinecone, pgvector, LangChain, DSPy, Microsoft Agent Framework, AWS, llama.cpp, vllm, tgi, ReAct
3w
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Software Engineer III/IV *Top Secret*
Hunt Valley, Maryland, United States
$111k-$210k/yr OnsiteFull Time
5+ YOEDesign, develop, and maintain software; embedded systems; UI development; AI integration; lead small teams; Secret/Top Secret clearance potential.
C#, C++, Java, Python, Embedded systems, FPGA, GPUs, Spectrum analyzers, Digital oscilloscopes
3w
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Software Engineer, I - Java
Fort Washington, Pennsylvania, United States
$90k-$100k/yr RemoteFull Time
2+ YOETwo+ years in Java 17+/Spring Boot; experience with React; healthcare IT standards; AI tools Claude; remote work; bachelor's degree or equivalent.
Java, Spring Boot, React, Delphi, Python, MySQL, MongoDB, Claude, AWS, Git, Subversion, REST, FHIR, HL7, CCDA, X12, Networking
5d
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AI Application Engineer
Malvern or Philadelphia or Charlotte
HybridFull Time
5+ YOEFive+ years related work experience with at least one year of development experience; undergraduate degree or equivalent.
Python, TypeScript, Stencil, AWS, Splunk, Honeycomb
1d
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Software Engineer - Early Career
King of Prussia, Pennsylvania, United States
OnsiteFull Time
0+ YOEBachelor’s degree in computer science or related field; Java development experience; experience with COTS/FOSS integration; ability to navigate Linux/Windows; U.S. citizenship and ability to obtain government security clearance (TS/SCI).
Java, Linux, Windows, COTS, FOSS, Agile, Angular, Oracle, Docker, SQL, Git, DevSecOps, Elasticsearch, Kubernetes, Kinetica, Python, AI/Machine Learning
1mo
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Senior Backend Engineer – AI Agent
Wilmington, Delaware, United States
RemoteFull Time
5+ YOE5+ years backend development; Python or Node.js; SQL/NoSQL databases; REST APIs; microservices; cloud (AWS/Azure/GCP); AI infra experience preferred.
Python, Node.js, SQL, NoSQL, RESTful APIs, Microservices, AWS, Azure, GCP, AI infrastructure
2mo
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Staff AI/ML Engineer (Large Language Model) (TS/SCI) {S}
King Of Prussia, Pennsylvania, United States
OnsiteFull Time
8+ YOE8+ years in software or data science; strong Python; LLM experience; TS/SCI clearance.
Python, NumPy, Pandas, Polars, scikit-learn, Git, GitLab, Bitbucket, LangChain, DSPy, Weaviate, Pinecone, OpenAI, Bedrock, llama.cpp, vllm, ReAct, PEFT, CUDA, CuPy, Numba, CuSignal, CuDF, AWS, EC2, S3, Lambda
2mo
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Full Stack Developer (Power Automate + AI)
Aberdeen, Maryland, United States
HybridFull Time
5+ YOE5+ years in software engineering; Power Automate and Power Platform expertise; DoD security clearance; strong stakeholder collaboration; secure integrations.
C#, .NET, Node.js, Python, Power Automate, Power Apps, Power BI, Dataverse, SharePoint, Azure, ALM, Graph/REST
3w
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Senior Computer Scientist/Engineer
Aberdeen, Maryland, United States
$125k-$225k/yr OnsiteFull Time
6+ YOEMaster’s degree in CS/engineering with 6+ years of experience; or 10 years of software/CS experience. Strong software development, AI, systems integration, and security clearance to Top Secret.
Python, C++, Java, Docker, Kubernetes, CI/CD, Git, Cloud
2w
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Reliability Engineer – Automation Engineer
Wilmington, Delaware, United States
$110k-$138k/yr HybridFull Time
Design, build, and operate reliable, scalable platforms using automation, IaC, CI/CD; Python automation; cloud platforms; vault/secrets management; AI-driven tooling.
Python, Terraform, Ansible, AWS, Azure, Vault
6h
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Data & AI Senior Engineer - 90405345 - Washington DC, Philadelphia PA, Wilmington DE or Chicago IL (Washington, DC, US, 20001)
Washington or Philadelphia or Wilmington or Chicago
$87k-$112k/yr OnsiteFull Time
4+ YOE4–6 years in data engineering, software development, or data architecture; Bachelor's in CS/Data Engineering or related field; onsite work across multiple cities.
Python, SQL, Spark, Databricks, SAP, Denodo, APIs, MLOps
1mo
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Program Manager - AI
West Chester, Pennsylvania, United States
OnsiteFull Time
CTDI: Repairs and manages logistics for telecommunications and electronic equipment.
3+ YOELead AI program initiatives; 3–5 years program optimization; BS in Systems Technology, Data Science, Software Engineering; Python coding; travel flexibility.
Python, Microsoft Office, Data Analysis
1w
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Lead, Technology Product Management – AI, Data & Insights
Titusville, New Jersey, United States
$109k-$175k/yr HybridFull Time
3+ YOE2+ MgmtBachelor in CS/IT/Data Science; 3+ years data & insights product development; proven LLM/GenAI production; Python/ML; cloud services; lead mid-large data teams; data engineering & science experience.
Python, LangChain, AWS, Azure, SageMaker, Bedrock, OpenAI, Azure ML, LLMs, Data Platforms, Cloud
2w
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Data Scientist, Ai Infrastructure and MCP (onsite)
Grand Island or San Marcos or Oceanside or San Clemente or Rockville or Escondido or Sparks or Buffalo or Baltimore
$88k-$116k/yr OnsiteFull Time
2+ YOE2+ years software engineering; Python APIs; data fundamentals; problem solving; cross-functional collaboration.
Python, APIs, PyTorch, TensorFlow, Hugging Face, LangChain, Vector databases, AWS
HiringCafe market data
Ai Python Software Engineer Jobs market signals in Lancaster, PA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
70
Hiring companies
22
Fresh sample
65% new in 30d
Salary visibility
45% show pay
Companies appearing in this market
JPMorgan ChaseLockheed MartinVanguardBlackRockComcastParsonsAmtrakARKA
Work location mix in visible results
Onsite: 23Hybrid: 15Remote: 2
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