Explore 2 algorithm developer jobs from 2 hiring companies in Brazoria, TX, US. Filter by remote, salary, experience, and company, then open any listing to apply.

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Algorithm Developer

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Algorithm Developer Jobs

Bastion Technologies

Baylor Genetics

Onsite

SUMMARY
We are seeking a highly experienced and innovative Senior Scientist in NGS Algorithm Development to lead the design, optimization, and implementation of computational algorithms for next-generation sequencing (NGS) data. This role focuses on detecting and interpreting a wide range of genomic features and chromosomal abnormalities, including trisomy, small variants, copy number variants, short tandem repeats, methylation patterns, and variants in homologous and homopolymer regions.
The Senior Scientist will also lead the design and optimization of targeted NGS panels for existing and new products and drive the development, validation, and integration of NGS algorithms and analysis pipelines. As a technical and project lead, this role ensures analytical accuracy, robustness, and scalability across products, supports technology transfer and pipeline updates, and collaborates cross-functionally with assay development, bioinformatics, and partner teams to provide technical guidance and inform strategic decisions.
The ideal candidate will hold a Ph.D. in Bioinformatics, Computational Biology, Genomics, or a related field, and have at least 5 years of hands-on experience in algorithm development for NGS applications. Experience in pharmacogenomics (PGx) variant calling, including complex loci such as CYP2D6, is strongly preferred.
Key Responsibilities
<ul>
<li>Lead the design, optimization, and implementation of scalable NGS algorithms and pipelines for detection and interpretation of complex genomic features, including SNVs/Indels, CNVs, STRs, methylation, trisomy, PGx variants, and variants in homologous and homopolymer regions</li>
<li>Lead the design and optimization of targeted NGS panels for existing and new products</li>
<li>Drive end-to-end development, validation, benchmarking, and integration of NGS algorithms and analysis pipelines using internal and public truth sets</li>
<li>Collaborate closely with assay scientists, bioinformatics teams, software engineers, and other partners to translate biological and product requirements into computational solutions</li>
<li>Provide technical and project leadership to ensure analytical accuracy, robustness, scalability, and continuous improvement across products</li>
<li>Support technology transfer, pipeline updates, and production deployment, and contribute to scientific publications, conference presentations, and intellectual property development.</li>
</ul>
Required Qualifications
<ul>
<li>Ph.D. in Bioinformatics, Computational Biology, Genomics, or a related discipline</li>
<li>Minimum 5 years of experience in NGS algorithm development</li>
<li>Proficiency in Python, R, C++, and workflow orchestration tools</li>
<li>Deep understanding of:
<ul>
<li>Read alignment and variant calling (e.g., BWA-MEM, minimap2, GATK, DeepVariant) for germline or/and somatic variants</li>
<li>CNV modeling, STR detection tools and methylation callers</li>
<li>Homologous region analysis and control gene normalization</li>
<li>PGx variant interpretation and allele resolution</li>
</ul>
</li>
<li>Experience with long-read technologies (ONT, PacBio) and signal-level data</li>
<li>Strong analytical, problem-solving, and communication skills</li>
</ul>
Preferred Qualifications
<ul>
<li>Somatic variant calling by short-reads or/and long-reads sequencing</li>
<li>Experience with machine learning models for variant classification</li>
<li>Knowledge of clinical genomics and regulatory standards</li>
<li>Familiarity with pharmacogenomic databases (e.g., PharmGKB, CPIC)</li>
</ul>
PHYSICAL DEMANDS AND WORK ENVIRONMENT
<ul>
<li>Frequently required to sit or stand for extended periods.</li>
<li>Frequently required to use hand and finger dexterity to operate laboratory equipment.</li>
<li>Frequently required to communicate verbally and visually interpret technical data.</li>
<li>Occasionally exposed to bloodborne or airborne pathogens or infectious materials.</li>
<li>Work is primarily performed in a laboratory and office environment.</li>
</ul>
EEO Statement: 
Baylor Genetics is proud to be an equal opportunity employer dedicated to building an inclusive and diverse workforce. We do not discriminate based on race, religion, color, national origin, sex, sexual orientation, age, gender identity, veteran status, disability, genetic information, pregnancy, childbirth, or related medical conditions, or any other status protected under applicable federal, state, or local law.
Note to Recruiters:
We value building direct relationships with our candidates and prefer to manage our hiring process internally. While we occasionally partner with select recruitment agencies for specialized roles, we do not accept unsolicited resumes from recruiters or agencies without a written agreement executed by the authorized signatory for Baylor Genetics ("Agreement"). Any resumes submitted to Baylor Genetics in the absence of an Agreement executed by Baylor Genetics' authorized signatory, will be considered the property of Baylor Genetics, and Baylor Genetics will not be obligated to pay any associated recruitment fees.

Sr Research and Development Scientist, Algorithm Developer

Research and Development Scientist

PhD in bioinformatics/genomics; 5+ years of NGS algorithm development; proficiency in Python, R, C++, workflow tools; experience with variant calling, CNV/STR/methylation analysis, PGx, long-read data; strong problem-solving and communication.

The Orion GN&amp;C Engineer will support the space program located in Houston, TX. 
 
RESPONSIBILITIES:
<ul>
<li style="background:#FFFFFF;vertical-align:baseline;">Develop and evaluate safety-critical, human rated GN&amp;C flight software.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Develop, integrate, and test new GN&amp;C algorithms.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Develop, integrate, and test new algorithms for evaluation of vehicle and mission performance.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Develop, integrate, and test new algorithms for trajectory optimizations.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Provide recommendations for improvements in design and software development processes.</li>
<li>Other duties as assigned. </li>
</ul>
 
REQUIRED:
This position has been posted at multiple levels (must meet minimum level indicated). Depending on the candidate's experience, requirements, and business needs, we reserve the right to consider candidates at any level for which this position has been advertised.
 
<ul>
<li style="background:#FFFFFF;vertical-align:baseline;"> This position requires US Citizenship or Permanent Resident status due to the sensitivity of customer related information.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Must have a bachelor's degree in the field of engineering.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Must have 1+ years of recent and related work experience.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with Kalman filters.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with development of modeling spacecraft systems performance.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Knowledge in the development of GN&amp;C algorithms and spacecraft system analysis.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with development and analysis of 6 DOF algorithms and simulations.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with orbital mechanics and GN&amp;C principles.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with design, verification, testing, and operation of GN&amp;C software.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with LINUX, Python, MATLAB, Simulink, and C/C++.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with Git/GitLab version control.</li>
<li style="background:#FFFFFF;vertical-align:baseline;">Experience with the development of space system requirements and documents.</li>
</ul>
 
DESIRED:
<ul>
<li>Knowledge of Artificial Intelligence and/or Machine Learning.</li>
<li>Experience with safety-critical, human-rated embedded software development.</li>
<li>Experience with Object oriented software development.</li>
<li>Experience with Agile software development.</li>
<li>Experience with spacecraft rendezvous, proximity operations, and docking.</li>
<li>Familiarity with spacecraft docking systems.</li>
<li>Working knowledge of NASA, JSC, and ISS standard practices and requirements (including safety).</li>
<li>Experience with NASA flight operations and procedures.</li>
<li>Familiarity with NASA/JSC documentation databases and SharePoint sites.</li>
<li>Experience with the NASA Trick simulation architecture and JEOD (JSC Engineering Orbital Dynamics).</li>
</ul>
 
WORK LOCATION: 
<ul>
<li>This position is located onsite and offers a 9/80 schedule with every other Friday off; some travel may be required. </li>
<li style="background:#FFFFFF;vertical-align:baseline;">Schedules are subject to change based on the requirements of the position and/or customer needs.</li>
</ul>
 
BACKGROUND INVESTIGATIONS REQUIRED:
All Bastion employees must be able to pass a national agency check and some positions require clearance and will require an extensive background verification/check process.
 
DRUG AND ALCOHOL SCREENING REQUIRED:
All Bastion employees must be able to pass a pre-employment drug screen and are required to participate in periodic random drug and alcohol screenings.
 
STANDARD BASTION REQUIREMENTS:
<ul>
<li>Must have experience with Microsoft Office Suite, Word, Excel, PowerPoint, and TEAMS.</li>
<li>All of Bastion's employees must be team players with strong work ethics and must be culture oriented.</li>
<li>Able to communicate effectively, verbally and in written form, with internal and external customers.</li>
<li>Able to follow company programs, processes, procedures, practices, requirements, goals, and objectives.</li>
<li>Must be organized with good time management skills and must be able to work outside normal schedule and adjust schedule to meet peak periods and surge requirements.</li>
<li>Generally, an office environment, but can involve inside or outside work depending on the task.</li>
<li>Work may involve sitting or standing for extended periods (90% of the time) and may require lifting and carrying up to 25 lbs. (5% of the time).</li>
<li>Regular attendance in accordance with an established work schedule is critical.</li>
</ul>
 
BASTION BENEFITS:
Bastion offers a wide range of benefits for their full-time employees; medical, prescription, dental, vision, AD&amp;D, disability benefits, life insurance, retirement 401k, vacation, sick pay, holidays, flexible work schedules (when available), along with many other options. We also support career advancement through professional training and development.
 
ABOUT BASTION:
Bastion offers career opportunities with competitive benefits, exciting possibilities for advancement, and an exceptional work environment; the well-being of our employees is a priority, and our flexibility allows our employees a great work life balance. Our culture is based on strong business ethics, integrity, and professionalism. Our team members are known for their initiative and high-quality work. When it comes to our employees, we value, respect, and help them grow in their careers.
 
WORKPLACE EXCELLENCE:
At Bastion, we are passionate about our people and our safety culture. Individual thoughts, opinions, and perspectives bring value and help us develop solutions for challenging problems, they make us more inventive, and more resilient.
 
All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, or other legally protected status.
 
Bastion participates in e-Verify.
 
#EntryLevel
 
#LI-Onsite
 
BT-26054

Orion GNC Engineer (BT-26054)

GNC Engineer

US citizenship or permanent residency; bachelor's in engineering; 1+ years related experience; Kalman filters; GN&C algorithms; Linux, Python, MATLAB, Simulink, C/C++; Git; space systems requirements.

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