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Backend Python Developer Jobs in Napa, CA, US

290+ backend python developer jobs from 180+ companies hiring in Napa, CA, US.

298 jobs- Napa • 50 miles
3mo
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Staff Software Engineer, Distributed Systems
San Francisco, California, United States
$250k-$300k/yr HybridFull Time
Ambience Healthcare
Ambience Healthcare: AI platform for medical documentation and clinical coding.
7+ YOE7+ years software engineering; 3+ years infra/backend; staff-level scope; strong Python/Go/TypeScript; Postgres; SF in-person 3x/week.
Python, Go, TypeScript, PostgreSQL
1mo
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Senior Software Engineer – Trust & Safety
San Francisco, California, United States
$167k-$251k/yr OnsiteFull Time
Quizlet
Quizlet: Online platform for digital flashcards and interactive study tools.
5+ YOE5+ years backend or platform engineering, strong experience with Node.js/Go/Python/TypeScript, distributed systems, security concepts, privacy/compliance awareness, on-call experience.
Node.js, Go, Python, TypeScript, OAuth2, SSO, MFA
2w
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AI Software Engineer - HP IQ
San Francisco, California, United States
$127k-$175k/yr OnsiteFull Time
HP
HPNYSE: HPQ: Produces personal computers, printers, and related digital imaging products.
1+ YOEMasters in CS/Engineering/Data Science/AI; 1+ years backend experience; Python, Java, C++; LLM integration; SQL/NoSQL; cloud-edge experience.
Python, Java, C++, LLM, PyTorch, TensorFlow Lite, ONNX Runtime, CoreML, SQL, NoSQL, APIs, Microservices, Cloud, Edge
4w
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Senior Software Engineer, Full Stack
San Francisco, California, United States
$180k-$200k/yr HybridFull Time
Gridware
Gridware: Real-time sensor platforms for power grid monitoring and safety.
5+ YOE5+ years of full-stack or product-focused software engineering; strong React/TypeScript frontend, Python/PostgreSQL backend; experience with GraphQL APIs; able to work in a low-structure, high-autonomy environment.
React, TypeScript, Python, PostgreSQL, GraphQL, OpenTelemetry, Grafana, Mimir
1w
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Senior Software Engineer, Security
San Francisco or Seattle
$165k-$230k/yr HybridFull Time
NexHealth
NexHealth: Connects patient experience software with electronic health records.
5+ YOE5+ years software engineering; 1–3+ years security; backend in Python/Go/Java; OAuth/JWT; AWS/Google Cloud; OWASP; SAST/DAST; RBAC; Bachelor's in CS/Engineering.
Python, Go, Java, OAuth 2.0, JWT, RBAC, OWASP, SAST, DAST, AWS, Google Cloud, CI/CD
2mo
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Software Engineer (Full Stack)
San Francisco, California, United States
OnsiteFull Time
Becoming
Becoming: Building robotic systems and AI to predict organism development.
1+ YOE1 year+ as a full-stack software engineer; strong frontend with React/TypeScript; strong backend with Python/Go/Rust/Node; API/data-model design; experience with time-series data; ability to work in fast-paced environment.
React, TypeScript, Python, Go, Rust, Node.js, APIs, Time-series data, Data pipelines
1mo
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Founding Senior Engineer (Hybrid + Equity)
San Francisco, California, United States
$80k-$120k/yr HybridFull Time
WingRep
WingRep: AI-powered platform providing real-time coaching for sales teams.
5+ YOE5+ years backend or full-stack experience; strong Python/TypeScript; design distributed systems; build async workflows, APIs, databases; eager to integrate AI; startup mindset.
React Native, Expo, TypeScript, Python, FastAPI, AWS, GraphQL, PostgreSQL, Aurora, S3, CDK, EventBridge, Bedrock, Pinecone
2w
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AI Software Engineer - HP IQ
San Francisco, California, United States
$127k-$175k/yr OnsiteFull Time
HP
HPNYSE: HPQ: Manufactures personal computers, printers, and 3D printing hardware.
1+ YOEMasters in CS/Engineering/Data Science/AI; 1+ year backend dev with Python/Java/C++; LLM integration; DB/streaming tech; problem-solving in agile env.
Python, Java, C++, PyTorch, TensorFlow, ONNX Runtime, CoreML, SQL, NoSQL, Kafka
2mo
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Principal Agentic AI Engineer
San Francisco, California, United States
$220k-$250k/yr OnsiteFull Time
Zeta Global
Zeta GlobalNYSE: ZETA: Provides AI marketing and consumer intelligence software for enterprises.
10+ YOE10+ years building production backend or applied AI systems; strong Java/Go (Python acceptable for evals); hands-on with LLMs, agentic patterns, RAG, and tool use; experience with observability and safety in production.
Java, Go, Python, AWS, LLMs, RAG, embeddings, tool use, APIs, microservices, distributed systems, telemetry, A/B testing, cache/store pipelines
2w
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Software Engineer
San Francisco or Vancouver
$150k-$300k/yr OnsiteFull Time
Gumloop
Gumloop: Platform for building AI automated workflows without code.
Build features end-to-end, ship quickly, collaborate with founders, create scalable frontend and backend systems.
Python, TypeScript, React, TailwindCSS
1mo
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Senior Software Engineer, Analytics Platform
San Francisco, California, United States
$190k-$280k/yr HybridFull Time
Sentry
Sentry: Developer platform for error tracking and performance monitoring.
4+ YOE4+ years backend/infrastructure experience; strong knowledge of distributed storage systems; Python proficiency; experience with PostgreSQL, ClickHouse, Memcached/Redis, Kafka/RabbitMQ; strong communication; located in or willing to relocate to San Francisco Bay Area.
PostgreSQL, ClickHouse, Memcached, Redis, Kafka, RabbitMQ, Python
1mo
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Staff Software Engineer, AI Operations
San Francisco, California, United States
$233k-$267k/yr HybridAll Commitments Available
Oura
Oura: Sells wearable smart rings for health and sleep tracking.
5+ YOE5+ years building production systems; experience with LLMs; backend (Python/Node.js); frontend (React/Next.js) or native; privacy by design; comfortable with ambiguity.
OpenAI, Anthropic, LangChain, LlamaIndex, Python, Node.js, React, Next.js, Swift, Kotlin, Claude Code, Cursor, LLM, MLOps
1mo
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Integration Engineer, People Technologies
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
CoreWeave
CoreWeaveNASDAQ: CRWV: Cloud platform providing GPU-accelerated infrastructure for AI workloads.
5+ YOE5+ years as a Full-Stack or Integration Engineer; strong React frontend; backend in Node.js/Python/Java; API/microservices; enterprise integrations; Workato/Boomi/Tray.io; Camunda/Airflow/Zapier; GenAI and cloud/AWS/GCP/Azure; data pipelines and API security.
React, Angular, Vue, Node.js, Python, Java, Workato, Boomi, Tray.io, Camunda, Apache Airflow, Zapier, OpenAI, LangChain, RAG, AWS, GCP, Azure, API security, Data pipelines
2mo
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Software Engineer, AI Systems & Infrastructure - AI Geospatial Assistant Team
San Francisco, California, United States
$145k-$181k/yr HybridFull Time
Planet
PlanetNYSE: PL: Provides daily satellite imagery and global Earth observation data.
4+ YOE4+ years backend experience Python/Go; AWS or GCP; Terraform; CI/CD; LangChain/LlamaIndex; vector search; Kubernetes/Docker; production AI systems.
Python, Go, AWS, GCP, Terraform, LangChain, LlamaIndex, Docker, Kubernetes, Ray Serve, CI/CD, Vector search, Distributed computing
1d
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AI Product Engineer
Sacramento, California, United States
$119k-$181k/yr OnsiteFull Time
CivicPlus
CivicPlus: Provides cloud-based software solutions for local government operations.
2+ YOE2+ years of production full‑stack software experience; backend in Go, Python, TypeScript; some LLM API integration; AWS experience; Claude Code/Cursor tooling; HTML/JavaScript; strong problem‑solving and communication; Bachelor’s preferred or equivalent experience.
Go, Python, TypeScript, AWS, Claude Code, Cursor, LLM APIs, CloudWatch
1mo
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Senior Software Engineer - Cloud (AWS) Account Management
Santa Monica or New York or Seattle or San Francisco or Glendale
$142k-$208k/yr OnsiteFull Time
The Walt Disney Company
The Walt Disney CompanyNYSE: DIS: Produces movies, operates theme parks, and provides streaming services.
5+ YOE5+ years software engineering; AWS experience; CI/CD tools; backend (Python, APIs); IAM/security; Docker; Unix/Linux; strong communication and collaboration.
Terraform, GitHub Actions, Spinnaker, Jenkins, Python, Docker, Unix/Linux
1mo
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Software Engineer
San Francisco, California, United States
$140k-$170k/yr OnsiteFull Time
CaseMark
CaseMark: AI-powered legal document summarization and workflow automation software.
Strong Next.js and TypeScript skills; backend API and database experience; able to integrate AI tools and LLMs; open-source mindset.
Next.js, TypeScript, Python, Rust, Go, PostgreSQL, Drizzle ORM, AWS, Vercel, OpenAI, Anthropic, OpenRouter, Modal, Vector databases
1mo
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Principal Software Engineer
San Francisco, California, United States
$164k-$257k/yr RemoteFull Time
ZoomInfo
ZoomInfoNASDAQ: GTM: Provides B2B contact data and sales intelligence software.
9+ YOE9+ years backend, data, or infrastructure engineering; distributed systems; big data; applied AI/ML; proficient in Java, Go, Python; strong SQL and data modeling; familiarity with ClickHouse, DynamoDB, Bigtable, Kafka, Kinesis, Snowflake; experience with LLMs and AI workflows.
Java, Go, Python, SQL, ClickHouse, DynamoDB, Bigtable, Memcached, Kafka, Kinesis, Firehose, Airflow, Snowflake, LangGraph, MCP
13h
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Staff Software Engineer
San Francisco or New York
$200k-$250k/yr HybridFull Time
Imprint
Imprint: Provides-branded credit cards and loyalty platforms for consumer brands.
8+ YOE8+ years software engineering; backend focus; Go/Java/Python; distributed systems; cloud (AWS/GCP/Azure); CI/CD; leadership; problem solving.
AWS, GCP, Azure, GitHub Actions, ArgoCD, Infrastructure as Code
1mo
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Staff AI Engineer – Agentic AI and Automaton
San Francisco or Lehi or Plano
$195k-$244k/yr HybridFull Time
Collective Health
Collective Health: Cloud platform for managing employer-sponsored health benefits.
10+ YOE10+ years of experience building scalable backend/data/AI systems; strong Java/Spring Boot and/or Python; cloud-native architectures (AWS/GCP); data pipelines; AI/ML integration; leadership and mentoring.
Java, Spring Boot, Python, AWS, GCP, Kubernetes, Docker, PostgreSQL, React, Angular, Claude Code, GitHub Copilot, Cursor, Gemini
1mo
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Lead Software Engineer – AI/RAG Platform
Atlanta, Georgia, United States
HybridFull Time
Floor & Decor
Floor & DecorNYSE: FND: Specialty retailer of hard surface flooring and related accessories.
7+ YOE7–10 years of software engineering; 2–5 production RAG agents; Python backend with LLM orchestration; Angular frontend; Azure OpenAI; REST APIs; MCP integration; Agile/Scrum experience.
Python, LangChain, Semantic Kernel, Azure OpenAI, Azure AI Search, MCP, Angular, REST APIs, RAG Architecture, Google, Git
2mo
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Senior Software Engineer - Cloud Account Management
Santa Monica or New York or Seattle or San Francisco or Glendale
OnsiteFull Time
Disney
DisneyNYSE: DIS: Produces films, operates theme parks, and provides streaming services.
5+ YOE5+ years software engineering; AWS cloud experience; CI/CD tooling (Terraform, GitHub Actions, Spinnaker, Jenkins); backend (Python, APIs); AWS IAM; Docker; Unix/Linux; strong communication.
Terraform, GitHub Actions, Spinnaker, Jenkins, Python, Docker, Unix/Linux
1mo
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Software Engineer
San Francisco, California, United States
$140k-$170k/yr OnsiteFull Time
CaseMark
CaseMark: AI platform for legal document summarization and workflow automation
Strong Next.js and TypeScript skills; backend experience with APIs and databases; experience integrating AI tools; open-source mindset; ability to read unfamiliar code and ship features.
Next.js, TypeScript, React, Python, Rust, Go, PostgreSQL, AWS, Vercel, OpenAI, Anthropic, OpenRouter
1w
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AI Machine Learning Engineer II (Intern) - United States
San Jose or San Francisco or Seattle or RTP
HybridFull Time
Cisco
CiscoNASDAQ: CSCO: Develops and sells networking hardware and cybersecurity software.
2+ YOEUndergrad 2 years relevant exp or graduate with 0 years; backend in Go or Python; LLM infra knowledge; AI/ML project experience.
Go, Python, vLLM, Triton, TorchServe
3mo
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Senior Software Engineer
Austin or San Francisco or New York
$180k-$260k/yr HybridFull Time
Pictor Labs
Pictor Labs: AI-powered virtual staining for digital pathology and tissue analysis.
5+ YOESenior software engineer with 5+ years in distributed systems, REST APIs, frontend/backend, cloud, and regulated environments.
Python, TypeScript, Node.js, React, AWS, Docker, Kubernetes, Terraform, Ansible, Git, SQL, NoSQL, CloudFormation, DataDog, Prometheus, Grafana, FDA 21 CFR Part 11, SOC2
2w
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Manager Software Engineer
South San Francisco or Salt Lake City
$141k-$177k/yr HybridFull Time
Myriad Genetics
Myriad GeneticsNASDAQ: MYGN: Offers genetic diagnostic tests to guide personalized medical care.
4+ YOE1+ Mgmt5+ years software development, 1-2+ years of management, Python backend, LIMS experience preferred, cloud/serverless, CI/CD, strong collaboration.
Python, FastAPI, Django, AWS, Kubernetes, LIMS, CI/CD, Data Pipelines
3w
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Senior Software Engineer, AI Voice Agent
San Francisco, California, United States
$150k-$220k/yr HybridFull Time
Aircall
Aircall: Cloud-based business phone system and customer communication platform.
5+ YOE5+ years production backend experience; Python or TypeScript; real-time systems; experience with LLM/AI in production; event-driven architecture; strong testing, observability, and design skills.
Python, TypeScript, Async programming, LLMs/AI tooling, API design, Datadog, Event-driven architectures, Caching, Messaging queues, Distributed systems, Observability, Testing, Design documentation
1d
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Senior Data Engineer
San Francisco or Denver or New York City
$110k-$130k/yr HybridFull Time
Forge Global
Forge GlobalNYSE: FRGE: Marketplace for trading private shares and pre-IPO stock.
3+ YOE3–5+ years with OO languages; Python for data tasks; data architectures; private markets experience; CI/CD; SQL/PostgreSQL; AWS/Azure/GCP; Git/GitHub; Jira; backend/frontend development.
TypeScript, C#, Java, Python, PostgreSQL, AWS, Azure, GCP, Git, GitHub, JIRA, Kafka, WebSockets, Medallion Architecture, Data Lakes
2mo
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Senior Machine Learning Engineer, AI Agents for Science, AI for Drug Discovery
New York City or South San Francisco
$160k-$297k/yr HybridFull Time
Roche
RocheSIX Swiss Exchange: ROG: Sells pharmaceutical drugs and medical diagnostic tests.
4+ YOE4–7+ years in agent systems, backend engineering, or equivalent; BS/MS or PhD with relevant experience; strong Python and distributed systems skills.
Python, FastAPI, asyncio, distributed systems, containerized environments, vector databases, machine learning, LLMs, RDKit, Biopython
2mo
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Staff AI Systems Engineer
United States or New York City or Boston or Chicago or Denver or Los Angeles or San Francisco or Austin
$200k-$225k/yr RemoteFull Time
Flock Safety
Flock Safety: Provides automated license plate readers and crime-solving software.
5+ YOE5+ years building and shipping ML systems; strong backend Python/JS; experience with LLM agents, ML platforms, cloud infra; observability and evals; remote work capable.
LangChain, LangGraph, vLLM, OpenAI API, Gemini API, Anthropic API, MCP, Postgres, Redis, Prometheus, Grafana, OpenTelemetry, LangSmith, Langfuse, TensorRT, PyTorch, Kubernetes, Terraform, Express, FastAPI, REST, SSE, JWT, AWS
2mo
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Software Engineer (Full Stack)
San Francisco, California, United States
$150k-$175k/yr OnsiteFull Time
Sandberg Goldberg Bernthal Family Foundation
Sandberg Goldberg Bernthal Family Foundation: Providing leadership training and community support for women.
3+ YOEFull Stack Software Engineer with 3+ years of experience; strong frontend and backend skills; independent worker; BS in CS or related field or equivalent experience.
React, Vue, Angular, HTML5, CSS3, Python, Node.js, Ruby, Java, SQL, NoSQL
2w
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Senior Software Engineer
San Francisco, California, United States
$170k-$200k/yr OnsiteFull Time
Instawork
Instawork: Digital marketplace connecting businesses with skilled hourly professionals.
5+ YOE5+ years in a high-growth product environment; full-stack with backend, APIs, and modern frontends; AI tooling; Agile; strong product instincts.
Django, Python, React, React Native
3mo
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Senior Full-Stack Software Engineer – AI Applications
Loveland or Santa Rosa
$120k-$200k/yr OnsiteFull Time
Keysight Technologies
Keysight TechnologiesNew York Stock Exchange: KEYS: Manufactures hardware and software for electronic test and measurement.
5+ YOEDesign and build end-to-end AI applications; develop frontend and backend; integrate AI workflows with hardware/software; ensure scalable, secure, production-ready systems.
React, Python, Node.js, REST, CI/CD, Cloud platforms
1mo
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Senior Software Engineer, Data Platform
San Francisco, California, United States
HybridFull Time
Plenful
Plenful: Automates administrative and operational workflows for healthcare organizations.
5+ YOE5+ years software engineering; backend or data infrastructure; relational databases; data modeling; production systems reliability; Python backend.
Python, PostgreSQL, AWS
3mo
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Senior Full-Stack Software Engineer – AI Applications
Loveland or Santa Rosa
$120k-$200k/yr HybridFull Time
Keysight Technologies
Keysight TechnologiesNYSE: KEYS: Provides electronic design, test, and simulation software and hardware.
5+ YOEDesign and implement end-to-end AI-based applications; build AI workflows; frontend and backend; secure SDLC; CI/CD; REST APIs; 5+ years full-stack; React; Python/Node.js.
React, Python, Node.js, REST APIs, CI/CD, Secure SDLC/SSDF
10h
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Staff AI Engineer
Frisco or San Francisco
$154k-$264k/yr OnsiteFull Time
SoFi
SoFiNasdaq: SOFI: Mobile-first platform for banking, lending, and investment services.
7+ YOE7+ years software engineering; experience building AI-powered systems; strong LLM, prompting, and agent frameworks; cloud experience; backend services; cross-functional collaboration.
Python, LLMs, APIs, LangGraph, cloud platforms (AWS/Azure/GCP), prompt design, retrieval-based approaches
2mo
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Staff Software Engineer, Identity & Trust
San Francisco, California, United States
$208k-$260k/yr OnsiteFull Time
Ripple
Ripple: Provide blockchain solutions for global payments and asset custody.
8+ YOE8+ years software engineering, backend focus, cloud-native distributed systems, API design, AWS and Kubernetes, leadership.
AWS, Kubernetes, ECS, REST, gRPC, Kafka, Spring Boot, Java, Go, Kotlin, C#, Python
2mo
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Senior Staff Software Engineer
Boston or Brooklyn or San Francisco or Washington
$225k-$265k/yr HybridFull Time
Altana
Altana: AI-powered network platform for global supply chain visibility.
12+ YOE12+ years backend or data-driven software; cloud deployments; lead engineers; strong communication; ownership of architecture and delivery.
Python, TypeScript, SQL, Docker, Git, Kubernetes, FastAPI, AWS, Azure, MLFlow, Temporal, Postgres, Databricks, OpenSearch
3mo
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Safety Engineer
Bangalore or Dublin or London or New York or San Francisco or Tokyo or Warsaw
RemoteFull Time
ElevenLabs
ElevenLabs: Develops AI audio models for human-like speech synthesis.
6+ YOE6+ years backend engineering; production systems; Python; AWS/GCP; Docker/K8s; observability; 0→1 product deployments; ML/AI systems integration
Python, AWS, GCP, Docker, Kubernetes, Prometheus, Grafana, Kafka, Redis, React
4d
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Senior Software Engineer (5+ years)
San Francisco or United States
$185k-$221k/yr HybridFull Time
Foresite Labs
Foresite Labs: Biotechnology incubator focused on AI-driven drug discovery and research.
5+ YOE5+ years of professional software engineering; strong TypeScript; one modern backend language; cloud and IaC experience; AI/LLM tooling; strong communication.
TypeScript, Python, Go, Java, AWS, Terraform, CDK, Pulumi, Docker, GitHub Actions, GitLab, LangChain, Pydantic AI, Claude Code, Codex

HiringCafe market data

Backend Python Developer Jobs market signals in Napa, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
290+
Hiring companies
180+
Fresh sample
36% new in 30d
Salary visibility
85% show pay

Companies appearing in this market

Zeta GlobalAmbience HealthcareCaseMarkHPKeysight TechnologiesNexHealthPlenfulQuizlet

Work location mix in visible results

Hybrid: 24Onsite: 19Remote: 4