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Lead Python Developer Jobs in West Wyomissing, PA, US
100+ lead python developer jobs from 29 companies hiring in West Wyomissing, PA, US.
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Lead Software Engineer II – Java & Python
Wilmington, Delaware, United States
$100k-$135k/yr RemoteAll Commitments Available
4+ YOE4-6 years of software engineering, strong Java/Python backend, AWS experience, SQL/NoSQL knowledge, CI/CD, Docker, and collaboration skills.
Java, Python, AWS, DynamoDB, RDS, PostgreSQL, DocumentDB, Docker, ECS, EKS, CloudWatch, Datadog, CI/CD
2mo
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Python, Cloud - Lead Software Engineer
Wilmington or Jersey City or Seattle
$152k-$215k/yr OnsiteFull Time
5+ YOE5+ years AI/ software engineering; Python expert; cloud-native; CI/CD; secure coding; AI SDKs; model deployment.
Python, Cloud (GCP/AWS/Azure), CI/CD, Terraform
2mo
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Lead Software Engineer- Python, Java
Columbus or Plano or Wilmington
OnsiteFull Time
5+ YOE5+ years of software engineering; strong Python and/or Java; open source experience; git proficiency; agile/CI-CD; system design; data concepts.
Python, Java, Git, GitHub, CI/CD, Pydantic, Pandas, Numpy, Jupyter
1mo
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Developer Team Lead
Allentown or Louisville or Providence
HybridFull Time
7+ YOEBachelor’s degree with 7+ years of related experience; strong software development background in languages such as C#, Java, Python; familiarity with emerging technologies; ability to lead a small team; experience in Agile environments.
C#, Java, Python, MEAN stack, MERN stack, Microservices, Cloud, APIs
5d
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Lead Software Engineer
New York or Holmdel or Bethlehem or Boston
$119k-$195k/yr HybridFull Time
10+ YOELead API-focused software engineer with 10+ years of distributed systems experience; strong Java, Node.js, .NET or Python API development and cloud/DevOps tooling.
Java, Spring Boot, Node.js, .NET, Python, React, Angular, TypeScript, Microservices, EIP, Event-Driven Architecture, OpenAPI, Swagger, OpenAPI/Swagger, OAuth 2.0, JWT, CI/CD, Bitbucket, Jenkins, AWS, GitHub, REST, GraphQL, gRPC, SOAP, Async/API-driven, Docker, Kubernetes, Helm, AWS S3, Lambda, Kafka, SQS, SNS, Redis, Prometheus, Grafana, OpenTelemetry, Splunk, OpenAPI, Swagger, SQL, NoSQL
1mo
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Lead, Software Engineer - Salesforce
Newark or Portland or Fort Washington or Washington Street, Newark
$134k-$220k/yr OnsiteFull Time
Lead Software Engineer - Salesforce with strong DevOps, security, and Salesforce expertise; proficient in Python/Java/JS; agile, collaborative leader.
Salesforce, Python, Java, JavaScript, React, Spring Boot, Node.js
2mo
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Lead Data Engineer (Bank Tech)
Wilmington, Delaware, United States
$179k-$205k/yr OnsiteFull Time
4+ YOELead data engineer with 4+ years in application development, 2+ years in big data, and 1+ year in cloud computing (AWS/Azure/GCP).
Java, Scala, Python, SQL, NoSQL, MongoDB, Cassandra, Redshift, Snowflake, Hadoop, Hive, Kafka, Spark, Gurobi, MySQL, Unix/Linux, Shell scripting
1mo
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Lead Software Engineer
Malvern, Pennsylvania, United States
HybridFull Time
10+ YOE5+ Mgmt10+ years leading omni-channel platforms; BS in Computer Science or related field; strong DevOps, REST, cloud, microservices; proficiency in multiple languages; databases; CI/CD; project tools.
Ruby, Rails, C# .Net, Python, Java, JavaScript, NodeJS, Rust, MongoDB, Postgres, Oracle, SQL Server, DB2, REST, SFTP/FTP, OAuth1, OAuth2, OIDC, TLS, SSH, CI/CD, JIRA, Azure DevOps, AWS, RabbitMQ, Kafka, Redis, Memcached, Hazelcast, Kubernetes, GitOps, Microservices, Cloud
4d
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Lead Analytics Engineer
Wyomissing or Harrisburg
OnsiteFull Time
3+ YOEThree+ years of related experience; strong Snowflake, SQL, Python; experience with data governance and cloud data architectures.
Snowflake, SQL, Azure, Python, dbt Core, dbt Cloud
4d
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Lead Analytics Engineer
Wyomissing or Harrisburg
OnsiteFull Time
3+ YOESnowflake, SQL, Python, Azure; data governance; 3+ years of related experience; Bachelor’s degree in a relevant field.
Snowflake, SQL, Azure, Python, dbt Core/Cloud
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Lead SIEM Engineer
Wilmington, Delaware, United States
$128k-$214k/yr HybridFull Time
5+ YOELead SIEM Engineer to design, implement, and manage SIEM infrastructure; senior role requiring leadership and strong SIEM expertise.
Splunk, IBM QRadar, Sumo Logic, Securonix, Python, PowerShell
1mo
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Lead Cloud DevOps Platform Engineer
Newark or Marlborough or Santa Clara
$128k-$201k/yr HybridFull Time
6+ YOELead DevOps role with 6+ years in cloud platforms (AWS/Azure/GCP), IAM, VPC, and managed services; strong Kubernetes, IaC, DevEx, security and regulatory compliance experience.
Kubernetes, Terraform, Pulumi, GitHub Actions, Azure DevOps, Jenkins, Ansible, HashiCorp Vault, AWS Secrets Manager, C#, C++, Python, Java
1mo
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Lead Software Engineer (Site Reliability)
Malvern, Pennsylvania, United States
HybridFull Time
Experience in distributed systems, cloud (AWS), Java/JavaScript, OpenTelemetry, microservices, observability, and incident response.
Java, JavaScript, Python, OpenTelemetry, AWS, Microservices, Observability
1w
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Palantir AIP & Foundry Lead Engineer
Camp Hill, Pennsylvania, United States
OnsiteFull Time
10+ YOEBachelor's degree in STEM; 3+ years with Palantir Foundry/AIP; proficiency in Python, SQL, PySpark, TypeScript; strong data and cloud/ frontend tooling experience; healthcare experience preferred.
Python, SQL, PySpark, Typescript
1mo
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Lead Data Engineer, Imagery Models
Hartford or Alpharetta or Richardson or Blue Bell or St. Paul or Hunt Valley
$161k-$266k/yr HybridFull Time
15+ YOEBachelor's in STEM; 15+ years data engineering; 4+ yrs AWS/Python; 3+ yrs Databricks; 2+ yrs imagery pipelines; strong leadership and communication.
AWS, Python, Databricks, APIs
1mo
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Lead Electrical Engineer 1 - Nuclear
Wilmington, Delaware, United States
$117k-$180k/yr OnsiteFull Time
10+ YOE3+ MgmtBS in electrical engineering; 10+ years in power plant electrical design; 3+ years leading design groups; experience with electrical systems; client liaison; PE licensure preferred; ability to be badged for unescorted nuclear access.
MS Office, Python, MATLAB, Excel
1w
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Lead EHV Engineer 2 - Grid
Wilmington, Delaware, United States
$132k-$205k/yr HybridFull Time
10+ YOEBSEE with power systems focus; 10+ years protection/control/telecom for HV substations; 3+ years 500kV/765kV design; strong reporting, coordination, and MS Office skills; ability to lead projects; not sponsoring work authorization.
AutoCAD, MicroStation, Bentley Substation, BlueBeam, Python, MATLAB, Excel, SDS design software
1mo
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Mechanical Engineer Lead - Loads & Dynamics
King of Prussia, Pennsylvania, United States
OnsiteFull Time
3+ YOE3+ years in loads and dynamics analysis and testing; aerospace/spacecraft experience; FEA/CFD; experience with Abaqus, NX/Nastran, ADAMS, Wave6, MATLAB, Python; active secret clearance.
Abaqus, NX/Nastran, ADAMS, Wave6, MATLAB, Python, FEA, CFD
1w
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Lead, Technology Product Management – AI, Data & Insights
Titusville, New Jersey, United States
$109k-$175k/yr HybridFull Time
3+ YOE2+ MgmtBachelor in CS/IT/Data Science; 3+ years data & insights product development; proven LLM/GenAI production; Python/ML; cloud services; lead mid-large data teams; data engineering & science experience.
Python, LangChain, AWS, Azure, SageMaker, Bedrock, OpenAI, Azure ML, LLMs, Data Platforms, Cloud
3w
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Vice President, Full Stack Engineer
Berwyn, Pennsylvania, United States
OnsiteFull Time
5+ YOELead design of server-side architecture; 5-9 years backend experience; finance industry; Java/Python/Node.js; Oracle databases.
Java, Python, Node.js, Oracle Database
2mo
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Senior Software Test Engineer (onsite)
New Freedom, Pennsylvania, United States
$80k-$110k/yr OnsiteFull Time
5+ YOESenior Software Test Engineer with 5+ years in software development and testing; 4+ years manual testing (preferably automated); proficient in C/C++, Python; hardware testing with oscilloscopes, logic analyzers, and JTAG; experience leading testing for embedded systems; US citizen or permanent resident.
C, C++, Python, Oscilloscopes, Logic Analyzers, JTAG
1mo
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Software Engineering Lead
Camden or Conshohocken
$140k-$160k/yr HybridFull Time
10+ YOE5+ Mgmt10+ years in software engineering; 5+ years in architectural roles; Python proficiency; REST APIs and event-driven design; Azure-native tech; CI/CD; strong multiple language and DB skills.
Python, REST APIs, Azure, Snowflake, CI/CD, Docker, Kubernetes
2mo
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Staff AI/ML Engineer (Large Language Model) (TS/SCI) {S}
King of Prussia, Pennsylvania, United States
OnsiteFull Time
8+ YOELead multidisciplinary AI/ML efforts; 8+ years in software/data roles with LLM experience; TS/SCI clearance; strong Python and ML libraries; experience with LLM deployment and RAG.
Python, NumPy, Pandas, Polars, scikit-learn, Git, GitLab, Bitbucket, Weaviate, Pinecone, pgvector, LangChain, DSPy, Microsoft Agent Framework, AWS, llama.cpp, vllm, tgi, ReAct
2w
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Staff Systems Engineer/Infrastructure Lead - Digital Products
Reading, Pennsylvania, United States
HybridFull Time
Penske Truck Leasing: Provides commercial truck leasing, rental, and vehicle maintenance services.
7+ YOE7+ years in network/systems engineering or cloud infrastructure; experience with digital products/SaaS; strong cloud, IaC, automation, containers, observability; Linux; security; Agile; ability to lead.
AWS, Azure, GCP, Terraform, CloudFormation, Python, Bash, Docker, Kubernetes, Openshift, Datadog, Prometheus, Splunk, Dynatrace, Linux, OIDC, SAML, IAM, Zero Trust, CI/CD, Infrastructure Automation
2w
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Lead Analyst, Collections Analytics
Wilmington, Delaware, United States
HybridFull Time
4+ YOEBachelor’s or Master’s in a quantitative field; 4+ years in analytics or software development in financial services; Python and SQL proficiency; Power BI; experience with large datasets and governance; Git familiarity.
Python, SQL, Power BI, Git, Object-Oriented Programming
1mo
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Sr. (Lead) Engineer I (II)
Audubon, Pennsylvania, United States
HybridFull Time
10+ YOEBachelor's in Engineering; 10+ years experience; 5+ years in quantitative and qualitative analysis; strong analytical and programming skills.
Python, PSSE, Dayzer, PROMOD, PLEXOS, PROBE, MATLAB, SAS
1mo
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Senior Controls Engineer
Baltimore or Newark or Allentown or Philadelphia
$85k-$120k/yr OnsiteFull Time
7+ YOE1+ MgmtLead design/implementation of control systems; strong PLC/SCADA/HMI, C/C++, Python; 7-10 years in industrial automation; Bachelor’s in Electrical/Control Systems engineering; forklift experience a plus.
PLCs, SCADA, HMI, embedded systems, C, C++, Python, simulation tools
2w
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Staff Systems Engineer/Infrastructure Lead - Digital Products
Reading, Pennsylvania, United States
HybridFull Time
7+ YOEBachelor’s or higher in CS/Engineering; 7+ years in network/systems/cloud; hybrid cloud, IaC, automation; containers/service mesh; Linux; security; Agile; travel; strong communication.
Terraform, CloudFormation, Python, Bash, Docker, Kubernetes, OpenShift, API gateways, service mesh, Datadog, Prometheus, Splunk, Dynatrace, Linux, Microsoft Entra ID, IAM, OIDC, SAML
2mo
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Senior Computer Vision AI/ML Engineer (TS/SCI) {S}
King of Prussia, Pennsylvania, United States
OnsiteFull Time
5+ YOESenior CV/AI-ML engineer with TS/SCI clearance, 5+ years experience, leading researchers and developers, expert in Python ML frameworks, remote sensing/ATR, cloud deployment.
Python, PyTorch, TensorFlow, Keras, scikit-learn, scikit-image, OpenCV, AWS
6d
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Data, Analytics & AI Team Lead
Atlanta or Houston or King of Prussia
HybridFull Time
10+ YOE5+ Mgmt10+ years in data analytics/engineering and AI with leadership and business development experience; strong stakeholder management and proposal skills.
Python, SQL, Cloud platforms, Power BI, Databricks, Snowflake
1mo
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Staff Engineer OT Digital Systems (Hershey, PA, US)
Hershey, Pennsylvania, United States
OnsiteFull Time
8+ YOELead digital systems and OT projects; MES, CW, and integration; 8 years experience in digital automation.
AVEVA PI, HiveMQ, OPC, MQTT, IEC 61131-3, Python, C#, SQL, VMWare, Kepware OPC, HMI/SCADA, Unified Namespace, ISA-95, Ignition, SAP, Augmentir, CW, CW Platform, Connected Worker
1w
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Principal Scientist, Spatial Omics
Cambridge or Spring House
$117k-$201k/yr OnsiteFull Time
6+ YOELead development and validation of spatial omics assays; PhD in a relevant field; 6+ years biotech/pharma experience; strong communication and collaboration skills.
Bruker CosMx, 10x Genomics Visium, Immunohistochemistry, in situ hybridization, Microscopy, Sequencing, R, Python
4w
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Internal Audit - Financial Crime AVP
Wilmington, Delaware, United States
OnsiteFull Time
Lead audits and risk assessments for financial crime; analyze data; communicate findings and recommendations; manage and develop a team.
Excel, Python, Tableau
6d
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Market & Business Intelligence Manager
Reston or Atlanta or Austin or Baltimore or Boston or Chicago or Dallas or Houston or Los Angeles or Miami or Minneapolis or Philadelphia or Phoenix or Raleigh or San Diego or Seattle or Short Hills or Washington DC or Wilmington
$113k-$165k/yr HybridFull Time
8+ YOELead analytics team; develop analytics strategy; collaborate with senior leaders; strong leadership and data analytics skills.
Azure, Fabric, Python, R, SQL, Power BI, Tableau
1mo
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IT Manager, Data Management, Analysis, Reporting & Development
Fairless Hills or Hatboro
OnsiteFull Time
7+ YOE3+ MgmtLeads enterprise data strategy, governance, data lake, analytics, BI and AI development; manages team; 7+ years data analytics/BI; 3+ years leadership; data lakes and ERP experience; SQL and data modeling; AI/ML experience preferred.
SQL, Data Modeling, ERP, Data Lake, BI, AI/ML, Python
HiringCafe market data
Lead Python Developer Jobs market signals in West Wyomissing, PA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
100+
Hiring companies
29
Fresh sample
43% new in 30d
Salary visibility
47% show pay
Companies appearing in this market
JPMorgan ChaseSargent & LundyARKA GroupCapital OneVanguardBest EggJohnson & JohnsonM&T Bank
Work location mix in visible results
Onsite: 28Hybrid: 22Remote: 3