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Lead Python Developer Jobs in United States
3,300+ lead python developer jobs from 1,200+ companies hiring in United States.
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Lead Python Developer, Data Analytics
United States
$68k-$199k/yr HybridFull Time
3+ YOE3+ years Python data engineering; SQL; Polars NumPy Pandas; XML/JSON/YAML; CI/CD; Git; cloud experience; Redis, Celery, PostgreSQL; XlsxWriter; React/HTML/CSS; DBT; English communication.
Polars, NumPy, Pandas, XML, JSON, YAML, Copilot, Claude, Git, CI/CD, Redis, PostgreSQL, Celery, XlsxWriter, React, HTML, CSS, DBT, Google Cloud Platform, AWS, Azure
2mo
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Lead Python developer (GenAI/Microservices focused)
Plano, Texas, United States
OnsiteFull Time
5+ YOE5+ years in software engineering; strong Python (FastAPI) and API design; AWS and microservices experience; GenAI integration (Bedrock); familiarity with vector stores; CI/CD and IaC; collaboration across teams.
Python, FastAPI, AWS, Terraform, CloudFormation, S3, Lambda, API Gateway, ECS, Fargate, OpenSearch, Elasticsearch, Bedrock, GitHub Actions, Jenkins, Terraform, Pinecone, Weaviate, OpenAI, OpenAI Bedrock, Streamlit
4w
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Lead Developer Python AI Gen
Irving, Texas, United States
HybridFull Time
6+ YOE6–9 years of Python development; strong GenAI/MLOps experience; data-centric engineering; cloud (AWS); DevOps, containers, CI/CD; focused on scalable Python services with AI integration.
Python, AWS, Docker, Kubernetes, CI/CD, Embeddings, Vector store, Retrieval-Augmented Generation, LLMs, GenAI
4w
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Lead Developer Python AI Gen
Irving, Texas, United States
HybridFull Time
6+ YOE6–9 years Python software development; GenAI and AI integration; data engineering; cloud (AWS); DevOps; collaboration.
Python, AWS, Docker, Kubernetes, CI/CD, LLMs, Embeddings, Vector Stores
2mo
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Lead AI Developer (Python)
Auburn Hills, Michigan, United States
OnsiteFull Time
7+ YOE7+ years software development; 3+ years AI/ML; Python and JavaScript; cloud platforms; ML frameworks; full-stack; Docker/Kubernetes; CI/CD; leadership.
Python, JavaScript, React, Node.js, AWS, Azure, GCP, TensorFlow, PyTorch, Scikit-learn, Docker, Kubernetes, MLflow, Airflow, SageMaker, Vertex AI
2mo
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Lead VBA/Python Principal Software Engineer
Boston or Smithfield or Merrimack
$107k-$216k/yr HybridFull Time
9+ YOE9+ years in software development in financial domain; strong Python/VBA, Excel, Front Office tooling; AWS/CI-CD; UI with Angular; CFA/FRM preferred.
Python, VBA, Excel, Angular, RESTful APIs, AWS, EKS, CI/CD, DevOps
2mo
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Python / AI Engineer
Washington, District of Columbia, United States
OnsiteFull Time
3+ YOEDesign, develop, and deploy AI solutions using cloud architectures and LLMs; lead projects; implement NLP, ML, and generative AI; ensure security and governance.
Python, TensorFlow, PyTorch, LangChain, LangGraph, Google Cloud, Azure, Azure Functions, Azure API Management, Azure Service Bus, Logic Apps, Azure Storage, Azure Cognitive Services, Azure Cosmos DB, Azure Data Factory, Databricks, Azure Data Lake, Splunk, AppInsights, Agentic AI
1w
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Python Software Engineer
Chicago, Illinois, United States
$92k-$164k/yr HybridFull Time
8+ YOE2+ Mgmt8+ years software engineering; 5+ years cloud (AWS); 5+ years APIs/microservices; 3+ years Python production; 2+ years leading teams; 2+ years Terraform; 2+ years CI/CD; 1+ year containers.
Python, Terraform, AWS, Docker, Kubernetes, GitHub Actions, Jenkins, FastAPI, Flask, API Gateway, Lambda, DynamoDB
1mo
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Lead Software Engineer II – Java & Python
Wilmington, Delaware, United States
$100k-$135k/yr RemoteAll Commitments Available
4+ YOE4-6 years of software engineering, strong Java/Python backend, AWS experience, SQL/NoSQL knowledge, CI/CD, Docker, and collaboration skills.
Java, Python, AWS, DynamoDB, RDS, PostgreSQL, DocumentDB, Docker, ECS, EKS, CloudWatch, Datadog, CI/CD
3w
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Apps Dev Tech Lead, Python Developer - Vice President - RUTHERFORD
Rutherford, New Jersey, United States
$142k-$213k/yr HybridFull Time
5+ YOE5+ years experience designing and developing scalable Python-based applications; proficient in Python, SQL, Spark, PySpark; knowledge of GenAI/LLMs; ability to work independently and in a team.
Python, SQL, Spark, PySpark, Linux, Shell scripting
1mo
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Lead Software Engineer - Python Developer
Plano, Texas, United States
OnsiteFull Time
5+ YOE5+ years software engineering with Python, hands-on design, automation, CI/CD, cloud knowledge, ML familiarity.
Python, Cloud, Machine Learning, CI/CD, Automation
8h
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Lead Software Engineer - Python
Houston, Texas, United States
OnsiteFull Time
5+ YOE5+ years software engineering; Python backend API; SQL databases; agile, CI/CD; AWS preferred; strong collaboration across teams.
Python, SQL, AWS
1mo
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Lead Software Engineer - Python
Westchester, Illinois, United States
RemoteFull Time
5+ YOEBachelor's degree or equivalent; 5+ years software engineering; proven delivery of programs on time and on budget; strong Python, C#/.NET, SQL; agile experience; effective communicator.
Python, C#/.NET, SQL, WCF, MVC, Entity Framework, Webservices
4w
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Lead Data Engineer (Oracle/Python)
Saint Petersburg, Florida, United States
HybridFull Time
6+ YOELead data engineer with Python and Oracle DB experience; CI/CD (Jenkins), Kubernetes, Pandas; 6-10 years experience; hybrid work in St. Petersburg, FL; visa sponsorship not available.
Python, Oracle, CI/CD, Jenkins, Kubernetes, Pandas
3w
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Lead Software Engineer (Python)
McLean or New York
$197k-$225k/yr OnsiteFull Time
4+ YOELead software engineer with 4+ years of experience, cloud experience (AWS/Azure/GCP), strong backend skills.
Java, Python, SQL, Node.js, Go, Scala, Docker, Kubernetes, AWS, RDBMS, NoSQL
1mo
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Lead Data Engineer (Python/SQL)
Milwaukee, Wisconsin, United States
OnsiteFull Time
Design, develop, and support data pipelines using Python, SQL, and BigQuery; collaborate with analysts; production support; lead code reviews; agile development.
Python, SQL Server, Google BigQuery, Google Cloud Composer
1w
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Senior Confluent Kafka Lead / Python Developer (Nashville, TN, US)
Nashville or Columbus
$82k-$193k/yr OnsiteFull Time
6+ YOE6–10+ years software/data engineering; 4+ years with Apache Kafka/Confluent; strong Python; cloud/hybrid deployments; CI/CD; IaC; Kafka security and governance.
Apache Kafka, Confluent Platform, Python, Kafka Connect, ksqlDB, Terraform, CloudFormation, ARM/Bicep, Docker, Kubernetes, GitHub Actions, Jenkins, GitLab, Azure DevOps, Prometheus, Grafana, Confluent Control Center
1w
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Technical Lead, Python Backend Engineer
United States
$85-$95/hr RemoteContract
6+ YOE2+ MgmtLead backend architecture and delivery of Python services on AWS; mentor team; ensure secure, scalable cloud-native systems.
Python, Javascript, SQL, REST API, OAuth 2, Docker, PostgreSQL, AWS, Kubernetes, EKS, Lambda, API Gateway, Jira, Bitbucket, GitHub, Slack, Teams, Pyramid, VSCode, Typescript, Snowflake, SQLAlchemy
1mo
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Lead Full Stack Engineer - React/Python
Chicago, Illinois, United States
$140k-$175k/yr HybridFull Time
7+ YOE7+ years in React, Python, and Node; REST & GraphQL; TypeScript; Jest; AWS/GCP; microservices; Git/Jira/Terraform; relational/noSQL databases; cloud logging and security.
React, Python, Node.js, REST, GraphQL, TypeScript, Jest, AWS, GCP, Terraform, Git, Jira, PostgreSQL, MySQL, Redshift, MongoDB, Redis, Cloud logging, Security tools
1w
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Lead Software Engineer
Austin, Texas, United States
OnsiteFull Time
5+ YOE5+ years software development; design of clean APIs in C++/Python; Python bindings for C++ (pybind11); build systems experience; data structures and algorithms; lead pipeline engine development.
C++, Python, pybind11, Make, CMake, Bazel
1mo
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Developer Team Lead
Allentown or Louisville or Providence
HybridFull Time
7+ YOEBachelor’s degree with 7+ years of related experience; strong software development background in languages such as C#, Java, Python; familiarity with emerging technologies; ability to lead a small team; experience in Agile environments.
C#, Java, Python, MEAN stack, MERN stack, Microservices, Cloud, APIs
1mo
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Software Engineer Lead (Mobile Developer)
Pittsburgh, Pennsylvania, United States
OnsiteFull Time
3+ YOELead software engineer for mobile development with strong Kotlin/Swift/Java/Python skills, native SDKs, backend fundamentals, CI/CD, UI/UX, and leadership.
Kotlin, Swift, Java, Python, Android Studio, Xcode, IntelliJ, REST, Kafka, Microservices, Spring Boot, CI/CD, UI/UX
1mo
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Lead IT Data Engineer (SQL/Python)
Springdale, Arkansas, United States
OnsiteFull Time
5+ YOELeads data strategy, cloud data platforms, governance, CI/CD for data pipelines, and agentic AI initiatives; 5+ years experience; Python/SQL; Databricks/Snowflake/BigQuery.
Python, SQL, Databricks, Snowflake, BigQuery, Kafka, Flink, Airflow, Dagster, dbt, Docker, Kubernetes, Terraform
1mo
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Lead Developer, Technology
Rockville or Washington or Tysons
HybridFull Time
7+ YOESenior software engineer with 7+ years in OO and database tech, Agile experience, and strong communication; able to mentor and lead development.
Java, Scala, Python, Object-Oriented Programming, Database Technologies, Agile, Test Automation, Build Automation, Configuration Management
2mo
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Lead Engineer - GenAI
Brooklyn Park or Sunnyvale
$132k-$286k/yr HybridFull Time
7+ YOESoftware development experience; GenAI focus; strong Java/Python skills; LLM experience; scalable systems.
Java, Python, PostgreSQL, OpenSearch, S3, LLM ecosystems, LangChain, LangGraph, Google GenAI
3w
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Software Engineer, Lead
Fort Meade or Laurel
$113k-$257k/yr HybridFull Time
12+ YOELead full-stack developer with Python, React, Linux, and Git; TS/SCI with poly; 12+ years or 16+ years without degree; ability to work with customers.
Python, JavaScript, React, Elasticsearch, Docker, Kubernetes, Linux, Git
4d
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Lead Software Engineer
New York or Holmdel or Bethlehem or Boston
$119k-$195k/yr HybridFull Time
10+ YOELead API-focused software engineer with 10+ years of distributed systems experience; strong Java, Node.js, .NET or Python API development and cloud/DevOps tooling.
Java, Spring Boot, Node.js, .NET, Python, React, Angular, TypeScript, Microservices, EIP, Event-Driven Architecture, OpenAPI, Swagger, OpenAPI/Swagger, OAuth 2.0, JWT, CI/CD, Bitbucket, Jenkins, AWS, GitHub, REST, GraphQL, gRPC, SOAP, Async/API-driven, Docker, Kubernetes, Helm, AWS S3, Lambda, Kafka, SQS, SNS, Redis, Prometheus, Grafana, OpenTelemetry, Splunk, OpenAPI, Swagger, SQL, NoSQL
1w
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Lead Consulting Developer- Python, AI/ML, Distributed System, Microservices
United States
$98k-$200k/yr OnsiteFull Time
6+ YOEBS/MS/PhD in Computer Science or related field with 6+ years of experience; strong Python; distributed systems and microservices; cloud experience; Agile; security/compliance awareness.
Python, Kubernetes, AWS, Azure, GCP, Oracle Cloud
2mo
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Lead Software Developer
Woburn, Massachusetts, United States
$157k-$223k/yr OnsiteFull Time
7+ YOELead software developer for embedded real-time signal processing; strong C/C++, GNU/Linux; Python/MATLAB; VHDL/Verilog; BS/MS/PhD; 7+ /5+ /2+ years experience; Top Secret clearance preferred.
C, C++, Python, MATLAB, GNU/Linux, VHDL, Verilog, IDEs, Version Control, Scripting
1mo
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Lead Platform Engineer
New York, New York, United States
$220k-$300k/yr OnsiteFull Time
Design, develop, and improve software with Python on AWS; lead a global front-office platform engineering function; ensure secure, scalable, high-quality software; strong collaboration and leadership.
Python, AWS, S3, Lambda, ECS/EKS, Step Functions, CloudWatch, Glue, CDK, CloudFormation, Databricks, SageMaker, LiteLLM, MLflow, Langfuse, Mem0, Observe
1mo
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Lead Developer
Fort Mill, South Carolina, United States
OnsiteFull Time
3+ YOESenior Java Engineer with backend, Java and Python, strong algorithms, CI/CD, and DevOps experience; financial services domain knowledge preferred.
Spring Boot, Redis, Apache Kafka, Docker, Kubernetes, REST APIs, Jenkins, GitLab, Java, Python, Oracle, PostgreSQL, SQS, Karate, Cucumber
3d
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Lead GenAI Cloud Developer
United States
$94k-$149k/yr RemoteFull Time
5+ YOELead GenAI cloud developer for ElasticGPT; advanced agentic capabilities; Python/TypeScript; Elasticsearch; Kubernetes; cloud infra; GenAI systems.
Python, TypeScript, PyTorch, TensorFlow, Hugging Face, Elasticsearch, Kubernetes, Docker, LangGraph, LangSmith, n8n, OpenTelemetry, OpenAI, Anthropic, Vertex AI, BM25, vector search, Confluence, Jira, GitHub, ServiceNow
2w
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Lead Developer
Virginia, United States
$92k-$175k/yr HybridFull Time
5+ YOE5+ years as software engineer; strong Java, Python, .NET; microservices, containers, REST/JSON; relational and NoSQL databases; design patterns; CI/CD and DevOps practices.
Java, Python, .NET, Docker, Kubernetes, REST, XML/JSON, Relational databases, NoSQL databases, CI/CD
1w
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Lead Developer
United States
$111k-$211k/yr RemoteFull Time
7+ YOE7+ years software engineering experience; strong Java, Python, .NET; microservices, containers (Docker, Kubernetes); relational and NoSQL databases; REST/JSON; architectural design and CI/CD.
Java, Python, .NET, Docker, Kubernetes, REST, XML, JSON, CI/CD
2mo
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Staff Software Engineer - Python
San Jose, California, United States
$177k-$262k/yr HybridFull Time
5+ YOE5+ years of backend development experience; Bachelor's degree or equivalent experience; strong Python backend skills; experience leading large-scale systems; knowledge of identity/authentication is a plus
Python, Django, Flask, OAuth2, SQL, NoSQL, Cloud, Microservices, Distributed Systems, Security Best Practices
2mo
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GIS Lead Developer
Denver, Colorado, United States
$92k-$118k/yr OnsiteFull Time
5+ YOE5+ years GIS development; Python, JavaScript/TypeScript, SQL; PostgreSQL/PostGIS; Snowflake; ArcGIS; data pipelines; UI/UX; cross-functional collaboration.
Python, JavaScript, TypeScript, SQL, PostgreSQL, PostGIS, Snowflake, ArcGIS, Dataiku, Leaflet, React, Git
2w
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Lead Development Engineer (Supply Chain)
Springdale, Arkansas, United States
OnsiteFull Time
5+ YOESenior software development lead with 5+ years in supply chain planning, Palantir Foundry or data-driven apps, and proficiency in Python, C++, JavaScript/React, SQL.
Palantir Foundry, Python, C++, JavaScript, React, SQL
4w
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Lead Full Stack Developer
Arlington or Herndon
$171k-$257k/yr OnsiteFull Time
7+ YOELead full stack developer with 7+ years; TS clearance with SCI eligibility; strong Python/JavaScript; in-person in Arlington/Herndon; BS in Computer Science or related field.
Python, JavaScript, Linux, Kubernetes, Jenkins, GitLab, AWS, OpenStack, Ansible, Terraform, OpenTofu
4w
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Lead Developer – Security Application Development (Back-End)
Cincinnati, Ohio, United States
$78k-$113k/yr OnsiteFull Time
8+ YOELead Backend developer with cloud security automation; proficient in Java/Spring Boot, Node.js, or .NET; REST APIs, CI/CD, Python for scripting, SIEM/EDR, cloud platforms.
Java, Spring Boot, Node.js, C#/.NET, REST, SQL, MS SQL, Azure, AWS, GCP, CI/CD, Git, Maven, Docker, Python, SOAR, Cortex XSOAR, Microsoft Sentinel, Dropzone AI, EDR, SIEM
1w
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Lead Enterprise Software Engineer
Cary, North Carolina, United States
$108k-$188k/yr HybridFull Time
Lead the design and development of complex software; mentor engineers; ensure quality and deployment; strong Java/Python/C#/CI skills.
Java, Python, C#, Git
HiringCafe market data
Lead Python Developer Jobs market signals in United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
3,300+
Hiring companies
1,200+
Fresh sample
52% new in 30d
Salary visibility
62% show pay
Companies appearing in this market
JPMorgan ChaseTyson FoodsBooz Allen HamiltonCapgeminiCapital OneCitiCognizantCVS Health
Work location mix in visible results
Onsite: 52Hybrid: 48Remote: 12