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Principal Python Engineer Jobs in United States
1,800+ principal python engineer jobs from 590+ companies hiring in United States.
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Principal Python Engineer
United States
RemoteFull Time
Senior Python engineer; design/own backend services, APIs; strong unit testing; DevOps practices; AI-enabled development.
Python, FastAPI, Temporal, Postgres, Docker, Kubernetes, Pulumi, Vue.js, SQL, Unit testing, CI/CD
1mo
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Principal Engineer
Atlanta, Georgia, United States
HybridFull Time
10+ YOE10+ years software engineering; principal/staff level; distributed systems; cloud-native; Java/C#/Python/Go; AWS; SQL Server; financial systems knowledge; strong communication.
Java, C#, Python, Go, ReactJS, SQL Server, AWS
1w
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Principal Engineer - Python API Development
Jersey City or Westlake
$107k-$216k/yr HybridFull Time
8+ YOE8+ years building/operating production platforms; expert in Python and distributed systems; Linux; AWS, CI/CD, IaC; ML/AI platform experience.
Python, Linux, AWS, S3, Lambda, Batch, Step Functions, CloudWatch, Jenkins, Git, Docker, Terraform, CloudFormation, SageMaker
3w
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Principal Engineer - Pricing Platform
Seattle, Washington, United States
$240k-$300k/yr OnsiteFull Time
10+ YOE10+ years software engineering; 3+ years in staff/principal; strong Python; ML/optimization; distributed real-time systems; cloud (AWS, GCP, Azure); security, observability, and cross-functional leadership.
Python, ML pipelines, cloud-infrastructure, data ingestion, model development, serving systems, monitoring
1mo
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Principal Engineer
Charlotte, North Carolina, United States
$159k-$254k/yr HybridFull Time
7+ YOESenior engineering leader; 7+ yrs engineering; 3+ yrs AI/ML; 3+ yrs streaming; 5+ yrs data architecture; 7+ yrs Java/Python; 3+ yrs APIs/microservices; 3+ yrs cloud-native; 5+ yrs system design; 3+ yrs security/governance
Java, Python, Kafka, Flink, REST, gRPC, Cloud-native platforms, OAuth / API security
3w
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Principal Engineer - AI Platform & Operations
Seattle, Washington, United States
$168k-$230k/yr HybridFull Time
12+ YOE12+ years of engineering experience; at least 4 years at Principal/Distinguished level; strong ML infra, Kubernetes, cloud (AWS/GCP/Azure); Python, Docker/Helm; MLflow, Weights & Biases, Kubeflow; experience with LLM inference at scale.
Triton, vLLM, Ray Serve, Kubernetes, AWS, GCP, Azure, MLflow, Weights & Biases, Kubeflow, Python, Docker, Helm
2mo
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Principal Engineer
Warrendale, Pennsylvania, United States
$100k-$120k/yr OnsiteFull Time
5+ YOEBachelor's in Electrical Engineering; 5-7 years in automated test fixtures; proficiency in Python, LabVIEW, MATLAB; hardware/software production troubleshooting; PCB/connector/sensor expertise; Altium, Pspice; FDA QSR/ISO (IEC 60601) design controls; project leadership; strong communication.
Python, LabVIEW, MATLAB, Altium, Pspice, Oscilloscopes, Signal generators
2mo
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Principal Engineer - Systems
Boulder, Colorado, United States
$88k-$232k/yr OnsiteFull Time
10+ YOEBachelor's in STEM; 10+ years systems engineering; Python/MATLAB; embedded systems; US citizenship; up to 15% travel.
Python, MATLAB, Oscilloscope, Spectrum Analyzer, Multimeter
1w
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Principal Software Engineer / Sr. Principal Software Engineer
Melbourne, Florida, United States
$98k-$184k/yr OnsiteFull Time
5+ YOEPrincipal/Sr. Principal Software Engineer with advanced STEM degree, strong C/C++ and Python, experience with CI/CD, embedded real-time software, and active Top Secret clearance.
C/C++, Python, Jira, Confluence, GitHub, GitLab, Jenkins, Docker, Kubernetes, Rhapsody, Cameo, VxWorks, Integrity, RTOS, Linux, DOORS, Fortify, SonarQube, Coverity
2mo
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Principal Engineer
Las Vegas, Nevada, United States
$170k-$210k/yr RemoteFull Time
8+ YOEEight+ years of power system planning, protection, or compliance experience in North America; strong NERC knowledge; PSSE/PSLF/CAPE experience; Python scripting; clear writing and communication.
PSSE, PSLF, CAPE, Python, PSCAD, EMT, ASPEN OneLiner, SIEMENS CAPE
1mo
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Principal Engineer
Dayton, Ohio, United States
OnsiteFull Time
12+ YOEActive DoD Top Secret security clearance with SCI eligibility; U.S. citizenship; BS in engineering; 12+ years of relevant experience; MBSE, AI/ML pipelines; leadership of junior engineers.
SysML, Java, C++, Python, DoDAF, UAF, Model Center, STK, UML, Rhapsody, Cameo/MagicDraw
1mo
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Principal Engineer, Hardware
Westford, Massachusetts, United States
$154k-$292k/yr OnsiteFull Time
10+ YOEMS or PhD in Electrical/Computer Engineering; 10+ years board/FPGA design; high-speed PCB design; Unix/Linux; Cadence tools; Python/Perl/TCL; strong debugging and communication.
Cadence System Capture, Python, Perl, TCL, Unix/Linux, Bus protocol analyzers, Oscilloscopes, Scripting and test automation
1mo
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Principal Engineer, Hardware
Westford, Massachusetts, United States
$154k-$292k/yr OnsiteFull Time
10+ YOEMS or PhD in Electrical or Computer Engineering; 10+ years in board/FPGA design; high-speed PCB design; Unix/Linux; Cadence System Capture; Python/Perl/TCL; strong communication.
Cadence System Capture, Python, Perl, TCL, Unix/Linux, Oscilloscopes, Bus Protocol Analyzers
1w
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Principal Software Engineer: Intra-Satellite Networking & Platforms - TeraWave
Seattle or San Francisco
$231k-$323k/yr OnsiteFull Time
Blue Origin: Develops reusable rockets and systems for human spaceflight.
15+ YOELead principal software engineer with 15+ years of software development, expert in C/C++/Python and network systems.
C, C++, Python, UDP, TCP/IP, Linux kernel networking, BSPs, FPGA, ASIC
1mo
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Principal Developer
Rosslyn, Virginia, United States
OnsiteFull Time
12+ YOE12+ years in software development/enterprise architecture; degree in CS/IT; Python/Java/C#; Agile/Scrum/SAFe; leadership and mentorship.
Python, Java, C#, Agile, Scrum, SAFe
1w
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Principal Engineer
United States
$190k-$230k/yr RemoteFull Time
10+ YOESenior software engineer with 10+ years of experience in system architecture and distributed systems; strong leadership without direct reports; cloud expertise and cross-functional collaboration.
AWS, GCP, Azure, React, .NET, Python
1mo
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Principal Systems Engineer
Hudson, New Hampshire, United States
$118k-$201k/yr OnsiteFull Time
6+ YOEActive Secret clearance; BS in related engineering/CS field; 6+ years in systems engineering; experience with SE processes; onsite work; Matlab/Python scripting.
Matlab, Python, Jira, Bitbucket, Confluence
1w
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Principal Engineer - Mission Performance
Aurora or Chantilly
$118k-$201k/yr OnsiteFull Time
6+ YOEBS or higher in Engineering; 6+ years related experience; TS/SCI clearance; Python; signal processing; documentation; communication; teamwork.
Python, STK, AFSIM
1mo
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Principal Engineer
Dayton, Ohio, United States
OnsiteFull Time
DCS Corporation: Provides engineering and technical services for national security programs.
12+ YOEU.S. citizenship required; active DoD Top Secret with SCI eligibility; bachelor’s in an engineering field with 12+ years of experience; master’s preferred; strong MBSE, AI/ML, and software skills.
Java, C++, Python, SysML, DoDAF, UAF, SysML 2.0, Modeling and simulation tools, UML, IBM Rhapsody, Cameo/MagicDraw, Model Center
1mo
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Principal Firmware Engineer
Folsom, California, United States
$150k-$318k/yr OnsiteFull Time
8+ YOEMaster’s or PhD in Electrical Engineering, Computer Engineering, Computer Science, or equivalent experience; 8+ years firmware in C/C++ and Python; strong SSD firmware and Linux knowledge.
C/C++, Python, Linux, SSD firmware, NAND flash
6d
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Principal Software Engineer
Redmond, Washington, United States
$140k-$275k/yr HybridFull Time
6+ YOE6+ years engineering experience; proficiency in C/C++/Rust/Python; security-focused hardware/firmware software work.
C, C++, Rust, Python, Java, JavaScript
2mo
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Principal Engineer - Autonomy & Robotics
San Francisco, California, United States
$92k-$148k/yr OnsiteFull Time
5+ YOEBachelor’s degree in Engineering or related field; 5+ years experience; proficient in C++ and Python; Linux experience; SQL; CI/CD; scripting (JavaScript).
C++, Python, Linux, SQL, CI/CD, JavaScript
2mo
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Principal Software Engineer
Milpitas, California, United States
$231k-$332k/yr OnsiteFull Time
15+ YOEEmbedded software engineering for BIOS/BSP, drivers, and diagnostics; strong C/C++/Python in Linux; hardware bring-up and validation.
C, C++, Python, Linux, I2C, SPI, UART, PCIe, GPIO
1mo
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Principal Systems Engineer
Hudson, New Hampshire, United States
$118k-$201k/yr OnsiteFull Time
6+ YOEBS in related field; 6+ years experience in systems engineering; secret clearance or higher; onsite lab work; Matlab/Python experience.
Matlab, Python, Lab instrumentation, Jira, Bitbucket, Confluence
5d
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Principal Mechanisms Engineer
Los Angeles, California, United States
$175k-$200k/yr OnsiteFull Time
8+ YOEBachelor’s in engineering; 8+ years in optomechanics or space mechanisms; CAD/FEA experience; design, testing, and production of mechanisms; Python/C++/MATLAB beneficial.
CAD (NX), FEM/FEA (Simcenter, FEMAP), HyperMesh, Python, C++, MATLAB
2mo
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Principal Software Engineer
Los Angeles, California, United States
$220k-$320k/yr HybridFull Time
10+ YOE10+ years software engineering; architecture leadership; cloud-native; Python, Rust or Go; DevOps; strong communication; 30% coding, 70% leadership.
Python, Rust, Go, CI/CD, infrastructure-as-code
3w
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Principal Engineer - AI Agents and Systems
Santa Clara or Redmond
$272k-$431k/yr OnsiteFull Time
15+ YOE15+ years software engineering; 3+ years in Principal/Lead Architect; BS/MS/PhD in CS/CE or related field; strong Windows OS, AI/GPU, and security expertise.
CUDA, TensorRT, Ollama, LlamaCpp, vLLM, OpenClaw, LangChain, AutoGPT, Python, C++, TypeScript
1w
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Principal Project Engineer
Mexico City or Medina
OnsiteFull Time
8+ YOEBachelor’s in engineering or related field; 8+ years in power systems or project engineering; travel up to 20%; experience with real-time control, OSI Monarch, and utility protocols; programming (Python, C/C++); databases; UNIX/Linux/Windows.
Python, C/C++, UNIX, Linux, Windows, Oracle, SQL Server, PostgreSQL, Mongo, Cassandra, JSON, XML, OSI Monarch, ICCP, DNP, MultiSpeak
1w
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Principal Product Engineer
Santa Clara, California, United States
OnsiteFull Time
7+ YOE7+ years in Product or MEMS engineering; BS/MS in EE, ME, Materials Science, Physics; data analysis skills (MATLAB/Python); experience with high-volume manufacturing and SPC.
MATLAB, Python, Exensio, JMP
1mo
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Principal Modeling Engineer
Lowell, Massachusetts, United States
$120k-$170k/yr OnsiteFull Time
7+ YOEBS/MS in Electronic Engineering; 7-10 years experience; device modeling; PDKs in Keysight ADS or Cadence MWoffice; RF/Microwave test; programming in Python; ITAR US Persons.
Keysight ADS, Cadence MWOffice, Python, Linux, RF/Microwave test equipment
1mo
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Principal Engineer, Hardware
Westford, Massachusetts, United States
$154k-$292k/yr OnsiteFull Time
10+ YOESenior hardware engineer with MS/PhD in Electrical or Computer Engineering; 10+ years board/FPGA design; expertise in high-speed PCB design, PCIe/Ethernet, SerDes, and lab debugging.
Cadence System Capture, Python, Perl, TCL, High-speed oscilloscopes, Bus protocol analyzers
1mo
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Principal AI Engineer
Seattle or San Jose
$186k-$280k/yr HybridFull Time
10+ YOE10+ years in software engineering with distributed systems; strong Python and Go/Java/TypeScript; production experience with LLM-based systems; experience with Vertex AI, Gemini, OpenAI APIs; Kubernetes and cloud-native architectures.
Python, Go, Java, TypeScript, Vertex AI, Gemini, OpenAI, LangChain, LlamaIndex, Kubernetes, Snowflake, Salesforce, ServiceNow, SharePoint
2mo
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Principal ML Engineer
Remote, Remote, United States
$150k-$200k/yr RemoteFull Time
6+ YOE6+ years in ML engineering with production ownership; expert Python; optimization (MILP/LP/Stochastic); ML (XGBoost, PyTorch); cloud-native pipelines on AWS/GCP/Azure; strong SQL and data-quality mindset.
Python, XGBoost, PyTorch, SageMaker, Airflow, OR-Tools, AWS, GCP, Azure, SQL
2mo
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MSI Data, LLC - Principal Engineer
United States
RemoteFull Time
10+ YOE10+ years software engineering; 3+ years integrating LLMs into production; proficient in Python/TypeScript; experience with OpenAI/Anthropic APIs, LangChain/LangGraph, vector databases; strong data engineering and high-throughput systems.
Python, TypeScript, OpenAI, Anthropic, LangChain, LangGraph, Pinecone, Milvus, SQL, REST, Next.js, React, Drizzle, PostgreSQL
3w
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Principal Engineer, Agentic Engineering
Saint Louis or Atlanta
HybridFull Time
7+ YOE7+ years software engineering; Java/Python/Go; AI-powered coding assistant experience; cloud-native design; microservices; CI/CD; leadership and mentoring.
GitHub Copilot, GitHub Actions, Jenkins, Kubernetes, Google Cloud Platform, AWS, Terraform, Helm, RBAC, ServiceNow, Datadog, GCP SDKs, GitHub
2mo
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Principal Controls Engineer
San Francisco, California, United States
$180k-$280k/yr OnsiteFull Time
5+ YOE5+ years in controls engineering with experience in motion planning, state estimation, and low-level robot control; strong background in control theory; proficient in C++/Python, ROS2, and real-time systems; Bachelor’s or Master’s in Robotics/ME/CS; PhD a plus.
C++, Python, ROS2, Real-Time Operating System, Kalman Filter, State Estimation
3w
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Senior Principal Electrical Engineer (Hybrid)
Cedar Rapids, Iowa, United States
$132k-$252k/yr HybridFull Time
10+ YOESenior Principal Electrical Engineer with 10+ years in ASIC/FPGA design, verification, SystemVerilog, VHDL; Linux, scripting; leadership in hardware development.
RTL, VHDL, Verilog, SystemVerilog, Questasim, Vivado, Libero, Synplify Pro, PCIe, DDR, I2C, Ethernet, ARINC-429, Python, C++, Linux
1mo
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Principal Engineer
United States
$170k-$200k/yr RemoteFull Time
10+ YOE10+ years in full-stack development; 5+ years in enterprise SaaS architecture; 2+ years real-time voice; 2+ years AI production; cloud/Kubernetes experience; agile; REST microservices; data analytics experience preferred.
Java, Node.js, Vue, Kubernetes, Kafka, Redis, NoSQL, REST, Python, GCP, AI/ML tools
1mo
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Principal Developer - IT
Chicago, Illinois, United States
$141k-$183k/yr OnsiteFull Time
7+ YOELead hands-on principal developer with 7-10+ years in IT solutions architecture; strong experience in CDP, identity graphs, AWS, Java/Python/.NET; design scalable, data-driven platforms with privacy compliance.
AWS, Java, Python, .NET, CDP, Identity Graph, Neptune Graph DB, Gremlin, Cypher
5d
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Principal Software Engineer, Cloud
San Diego, California, United States
$180k-$230k/yr HybridFull Time
12+ YOE12+ years in software engineering/cloud architecture; proven leadership; strong Go/Python; GCP, Kubernetes, Terraform/Pulumi; distributed systems; GenAI tooling.
Go, Python, Google Cloud Platform, Kubernetes, Docker, Terraform, Pulumi, Pub/Sub, Kafka, Bazel
HiringCafe market data
Principal Python Engineer Jobs market signals in United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
1,800+
Hiring companies
590+
Fresh sample
40% new in 30d
Salary visibility
87% show pay
Companies appearing in this market
BAE SystemsHewlett Packard EnterpriseBlue OriginF5Fidelity InvestmentsK2 SpaceMACOMMicron Technology
Work location mix in visible results
Onsite: 59Hybrid: 36Remote: 7