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Python Developer Jobs in Columbus, IN, US
98 python developer jobs from 48 companies hiring in Columbus, IN, US.
1d
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Senior Firmware Developer Engineer
Columbus, Indiana, United States
HybridFull Time
7+ YOE7+ years of firmware development; embedded Linux; C++, Python; CI/CD; OSS management; hardware debugging; cybersecurity exposure.
Embedded Linux, C++, Python, Yocto, Buildroot, OpenWRT, Azure DevOps, Jenkins, OSS (Open Source Software)
1d
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Software Engineer, AI & Clinical Applications
Indianapolis, Indiana, United States
$65k-$158k/yr HybridFull Time
3+ YOE3+ years full-stack development with Python; AI/LLM experience; regulated clinical environment knowledge; strong communication.
Python, JavaScript, TypeScript, SQL, R, React, Vue.js, FastAPI, Flask, Node.js, GraphQL, Pandas, NumPy, PySpark, SAS, SAS Viya, CDISC SDTM, ADaM, AWS, Azure, Docker, CI/CD, Git, PostgreSQL, SQL Server, Oracle, 21 CFR Part 11, MCP, LangChain, LangGraph, AutoGen
1mo
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Systems Engineer
Bloomington, Indiana, United States
$95k-$140k/yr RemoteFull Time
Distributed systems, APIs, on-premise deployment, event-driven architectures; Python/C++.
Python, C++, Docker, Kubernetes, Apache Kafka, RabbitMQ
1w
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Senior Software Engineer
Plano or Columbus or Boston or Portsmouth or Indianapolis
$106k-$197k/yr HybridFull Time
5+ YOEFive+ years software engineering; strong Python/Java; AWS; RESTful services; React/Node.js; Agile experience.
Python, Java, React, Node.js, Spring Boot, AWS, RESTful services, RDS
1w
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Senior Engineer, Control Systems Simulation
Indianapolis, Indiana, United States
OnsiteFull Time
7+ YOE7+ years software engineering in C, C++, C#, Python, Rust; develop data-collection/tools for embedded controls; GitHub; Visual Studio/VS Code; BS in engineering or CS.
C, C++, C#, Python, Rust, GitHub, Visual Studio, VS Code, Veristand, LabView, Matlab, Simulink, CMMI, SPICE
1w
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Employee Success Lead Data Engineer
Indianapolis or Atlanta or Austin
HybridFull Time
10+ YOELead data engineer with 10+ years of experience in data engineering, data modeling, ML, automation, analytics; strong SQL, Python; API development; experience with AWS, Data360, Snowflake preferred.
SQL, Python, Informatica IICS, dbt, Apache Airflow, Git, AWS, Salesforce Data360, Snowflake, Bash
6d
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Sr. AI Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
5+ YOE5+ years AI/ML engineering; senior-level experience; production AI agents; large-scale enterprise data; AWS Bedrock/Lambda; RAG and MCP; Python, PyTorch/TensorFlow; security/compliance.
AWS Bedrock, AWS Lambda, Python, PyTorch, TensorFlow, SQL, PySpark, LangChain, LangGraph, vector databases
1mo
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Software Engineer I WSI
Indianapolis, Indiana, United States
OnsiteFull Time
Entry-level software engineer with C++, Python, or Java; Git; RTOS; avionics interfaces MIL-STD-1553/1760; Ethernet; scripting; testing and documentation.
C++, Python, Java, Git, GitHub, RTOS, MIL-STD-1553, MIL-STD-1760, Ethernet, UART, SPI, I2C, Qt, JUnit, pytest, Jenkins, GitHub Actions, Bash
2mo
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Senior Software Engineer
Indianapolis, Indiana, United States
$80k-$100k/yr HybridFull Time
4+ YOE4+ years software development; Django experience; cloud deployment; REST APIs; HTML/CSS/JavaScript; Postgres; CI/CD; AI exposure (nice to have).
Django, Python, REST, PostgreSQL, HTML, CSS, JavaScript, Google Cloud Platform, CI/CD
3w
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Principal Innovation Engineer
Minnetonka or Austin or Chicago or Dallas or Detroit or Atlanta or Houston or Akron or Birmingham or Charlotte or Indianapolis or Pittsburgh or Cincinnati or Cleveland
$102k-$208k/yr OnsiteFull Time
10+ YOEBachelor’s degree in Computer Science or related field; 10+ years in software engineering and architecture; hands-on end-to-end development; experience with AI-enabled applications and API/integration patterns; ability to lead complex initiatives in fast-paced environment.
Java, Python, TypeScript, JavaScript, React, Next.js, APIs, Workflow automation, Cloud platforms, Vertex AI, Gemini
2mo
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Sr. R&D Software Engineer
Boise or Indianapolis or Dallas or Farmers Branch
OnsiteFull Time
Lead software teams; strong mentorship; experience with C++, Python; ROS; Linux; CI/CD; design and architecture of software for robotics.
C++, Python, Linux, Git, ROS, Docker, Singularity, OpenCV, PCL, HTML, CSS, JavaScript, CANOpen, Serial, SPI, Ethernet/IP, Sockets
1w
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Sr. Product Software Engineer - AI
Coppell or Tampa or Kennesaw or Riverwoods or Chicago or Wichita or Indianapolis or Greenwood Village
$93k-$162k/yr HybridFull Time
3+ YOE3+ years software development; full-stack; Agile/XP with TDD/BDD and pair programming; experience with AI tools and ML workflows.
Python, JavaScript/TypeScript, GitHub Copilot, LangChain, Hugging Face, OpenAI, Azure AI, GenAI tools
2mo
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Senior Full-Stack Engineer
Culver City or Linthicum or Allen or Woodcliff Lake or Chicago or Orlando or Baton Rouge or Waltham or Phoenix or Harrisburg or West Valley City or Austin or Alpharetta or San Diego or Indianapolis or Lexington or Parma or Little Rock or Asheville or Birmingham or Chantilly or Washington or Brentwood or Plantation or Fort Collins or San Mateo or Schaumburg or Brooklyn
$140k-$180k/yr OnsiteFull Time
7+ YOE7+ years in software development; Bachelor's degree in CS/Engineering; backend (Node.js) and frontend (React) experience; API integrations; cloud and database experience.
Node.js, HapiJS, Python, JavaScript, React, SQL, Serverless, Lambda, CloudFormation, Elastic Beanstalk, EC2, VPC, DynamoDB, RDS, G Suite, Microsoft Graph, Okta, OneLogin, Slack, Linux, Docker, Datadog, CloudWatch, MQTT, log/data pipelines
1mo
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FPGA Engineer (IN, Indianapolis)
Indianapolis, Indiana, United States
OnsiteFull Time
EndoSec: Security software and cryptographic hardware for government and defense.
Design, develop, test IP cores and FPGA systems; RTL/C/C++, Python; VHDL/Verilog; hardware security; government clearance readiness.
RTL, C/C++, Python, VHDL, Verilog, Tcl, Vivado, GHDL, Questa, Quartus Prime
4w
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Senior Salesforce Developer
Chicago or Los Angeles or New York or Oakbrook Terrace or Sacramento or San Francisco or South Bend or San Jose or Tampa or Atlanta or Boston or Columbus or Dallas or Denver or Fort Lauderdale or Grand Rapids or Houston or Austin or Charlotte or Indianapolis
$109k-$222k/yr HybridFull Time
5+ YOE5+ years Salesforce experience; proficient in Apex, Visualforce, Aura, LWC; strong frontend skills; Salesforce API; certifications preferred
Salesforce, Apex, Visualforce, Aura Components, Lightning Web Components, Salesforce API, Heroku, AWS, Python, Node.js
1mo
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Ecosystem Engineer
Roswell or Dallas or Indianapolis
OnsiteFull Time
5+ YOEBachelor's degree in computer engineering or related field; 5+ years in ecosystem engineering, systems integration, product development; cybersecurity, embedded systems, IoT, programming in C/C++, Python, Java; experience with SE processes and NIST; strong communication and leadership.
C/C++, Python, Java, Jama, Doors, Helix, Robot Framework, Selenium, Appium, MQTT, Modbus, BACnet, Six Sigma
5d
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2026 Raytheon Full Time- Software Data Engineer II (Onsite)
Indianapolis, Indiana, United States
$69k-$131k/yr OnsiteFull Time
Master’s degree in CS/Software/Data Eng or related; Python and SQL; JavaScript/HTML/CSS; Agile; data engineering concepts.
Python, SQL, Git, dbt, Docker, Kubernetes, HTML, CSS, JavaScript
1w
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Software Engineer, Senior
Indianapolis, Indiana, United States
OnsiteFull Time
5+ YOESenior software engineer with 5+ years experience, cloud-native apps, CI/CD, REST APIs, databases, and strong communication
C#, DotNet, Python, REST, SQL, PostgreSQL, DynamoDB, MongoDB, React, TypeScript, Terraform, Kubernetes, Docker, AWS
1mo
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Principal Software Engineer
Indianapolis, Indiana, United States
$140k-$180k/yr HybridFull Time
8+ YOE8+ years software engineering; TypeScript, Node.js, React; distributed systems; cloud (AWS/GCP); SQL; data pipelines; ML workflows a plus; remote-friendly.
TypeScript, Node.js, React, Vue.js, Python, SQL, Snowflake, BigQuery, dbt, Airflow, AWS, Google Cloud, GitHub Copilot, Claude Code
20h
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AI Engineer / Data Engineer (Indianapolis, IN / Onsite)
Indianapolis, Indiana, United States
$120k-$155k/yr HybridFull Time
3+ YOEStrong SQL, Python, ML/MLOps, data engineering, and software engineering skills with production AI/ML experience.
Python, SQL, PyTorch, TensorFlow, scikit-learn, MLOps, AWS, Azure, GCP, Snowflake, Docker, CI/CD
1w
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Analytics Engineer
Austin or Denver or Indianapolis or Los Angeles or Minneapolis or Nashville or New York or Salt Lake City or San Francisco or Seattle
$120k-$140k/yr RemoteFull Time
2+ YOE2+ years in analytics engineering or data engineering; strong SQL; Snowflake; dbt; Python; data modeling; stakeholder collaboration; problem solving.
Snowflake, dbt, SQL, Python, Hex
2mo
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ML Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
Experience as a Data Analyst/Engineer with AI/ML, Python/R/SQL, ML frameworks; onsite in Indianapolis; US work authorization without sponsorship.
Python, R, SQL, TensorFlow, PyTorch, Snowflake Cortex
1mo
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Data Engineer
Indianapolis, Indiana, United States
HybridFull Time
7+ YOE7+ years in data engineering; experience leading projects; Azure data platforms; SQL; Python/PySpark; data governance; documentation; collaboration with legal teams.
Azure, Microsoft Fabric, Azure Synapse Analytics, ADLS Gen 2, Synapse SQL Pools, Azure Data Factory, Power BI, Power Automate, Power Apps, SQL, SSIS, SSRS, Python, PySpark
2w
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Data Engineer
Portsmouth or Boston or Plano or Indianapolis
HybridFull Time
3+ YOE3+ years data engineering; strong SQL, Python/Java, AWS; Snowflake, IDMC; ETL/ELT design; data modeling and governance; cross‑functional collaboration; proactive andMentor-ready.
Snowflake, IDMC, Python, Java, SQL, AWS, Power BI, Erwin, PostgreSQL, FCS
2mo
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Electrical Engineer (Hardware)
Indianapolis, Indiana, United States
OnsiteFull Time
3+ YOEBachelor's in Electrical Engineering; 3-5 years experience; hardware design, PCB layout, firmware; C/C++, Python; Agile knowledge.
C, C++, Java, Python, Altium, OrCAD, AutoCAD, MATLAB, SPICE
1w
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Data Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
2+ YOEBachelor’s degree; 2-4 years data engineering; Snowflake SQL/T-SQL; Python; Azure; APIs, version control (Git); CI/CD; reporting experience; sports/entertainment experience preferred.
Snowflake, SQL, T-SQL, Python, Microsoft Azure, GitHub, Matillion, Power BI, Salesforce, Ticketmaster, Fanatics
2mo
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Junior Database Developer
Indianapolis, Indiana, United States
OnsiteFull Time
3+ YOEBachelor's in CS/IT or related field; 3-5 years in DB administration/IT; SQL proficiency; experience with SQL Server, Oracle, MySQL, PostgreSQL; cloud DB platforms; scripting (PowerShell, Python, Bash); BI/reporting data analytics experience.
SQL, Microsoft SQL Server, Oracle, MySQL, PostgreSQL, AWS RDS, Azure SQL Database, Google Cloud SQL, PowerShell, Python, Bash
4d
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Digital Innovation Engineer
Wilmington or Florence or Auburn Hills or Irving
HybridFull Time
1+ YOEMaster's degree or higher, or equivalent experience in CS/ML/physics/applied math; 1+ year modeling/data analysis; AI + physics ML; materials knowledge a plus; statistical modeling; experimental design; uncertainty quantification.
Python, Machine Learning, Bayesian Optimization, Statistical Modeling, SQL, R
1d
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Cloud Infrastructure Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
3+ YOE3+ years in cloud computing; AWS required; Terraform IaC; CI/CD; Python/Bash scripting; monitoring and DevOps/InfraOps experience.
AWS, Terraform, CI/CD, CloudWatch, Python, Bash
2w
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Gen AI Engineer
Atlanta or Richmond or Lake Mary or Nashville or Indianapolis or Wilmington or Mason or Grand Prairie or Norfolk
HybridFull Time
4+ YOEBachelor’s in a quantitative field or equivalent with 4+ years of experience; advanced Python; experience with ML/NLP/LLM; cloud platforms; strong collaboration skills.
Python, SQL, Hugging Face, TensorFlow, Keras, PyTorch, Spark, GCP, AWS, Azure
1mo
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Sr. Automation/Controls Engineer
Indianapolis, Indiana, United States
$142k-$171k/yr OnsiteFull Time
7+ YOE7+ years in automation/control engineering in pharma or regulated manufacturing; PLC/SCADA/HMI design; GMP knowledge; building automation systems; programming in C++, Python, Java.
PLC, SCADA, HMI, DeltaV, Johnson Controls BMS, Siemens FMCS, C++, Python, Java
3w
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Site Reliability Engineer - Observability
Indianapolis, Indiana, United States
HybridFull Time
3+ YOE2-5 years in IT support or SRE roles; strong observability, incident management, root cause analysis; collaboration with development teams.
Splunk, OpenTelemetry, AppDynamics, Datadog, AWS, Kubernetes, OpenShift, Python, Linux, Mulesoft, Postman
2w
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AI / Machine Learning Engineer
Indianapolis, Indiana, United States
$102k-$170k/yr HybridFull Time
3+ YOE3–5 years in ML/AI, Python with ML frameworks, SQL/Pandas/NumPy; DoD/IC experience preferred; US citizenship and active Secret clearance; bachelor's degree.
Python, scikit-learn, PyTorch, TensorFlow, SQL, Pandas, NumPy, Databricks, Spark, MLflow, Delta Lake
2mo
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Azure Cloud Databricks Lead Developer
Cincinnati or Indianapolis
OnsiteFull Time
4+ YOE1+ MgmtBachelor's degree or foreign equivalent; 4+ years IT experience; Azure Databricks, Spark; Spark, Kafka, Airflow, SQL, Python; data warehousing knowledge; leadership experience; willing to travel; US work authorization.
Spark, Kafka, Airflow, SQL, Python, GitLab CI, GitHub Actions, Azure Pipelines, Jenkins, Databricks
1mo
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Prognostics & Health Management (PHM) Engineer - F130
Indianapolis, Indiana, United States
$94k-$153k/yr HybridFull Time
2+ YOEBachelor's or Master's in engineering/science with PHM/EHM experience; U.S. citizen. Proficiency in Python, SQL; MBSE experience helpful.
Python, SQL, MBSE, Cameo Systems Modeler
1mo
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DevOps Engineer
Fort Wayne or Indianapolis
HybridFull Time
5+ YOEBachelor’s degree in computer programming, computer science, information technology, or equivalent; 5+ years IT experience; strong CI/CD, IaC, scripting; Azure preferred; cloud/on-prem environments; experience with GitLab CI, Azure DevOps, Jenkins.
Git, GitLab, GitLab CI, Azure DevOps, Jenkins, Ansible, Docker, Kubernetes, PowerShell, Bash, Markdown, YAML, Linux, Windows, C#, .NET, Java, Python, Cloud - Microsoft Azure
1w
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Lead Engineer
Indianapolis, Indiana, United States
OnsiteFull Time
Architect and build enterprise AI platform; design distributed systems, ML infra, and MLOps; onsite in Indianapolis; US work authorization; visa sponsorship not available.
Python, Go, Kubernetes, GPU acceleration, Infrastructure-as-Code, gRPC, Temporal, Argo, Flux, S3, Langchain, FastAPI, OpenAI APIs, AW S Bedrock, Azure OpenAI, Google Vertex, PEFT, LoRA, RAG, Prometheus, Grafana, Redis, Langgraph
1mo
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Senior AI/ML Engineer (Data Science & Automation)
Indianapolis, Indiana, United States
OnsiteFull Time
7+ YOE7+ years in data science/AI/ML; production ML; cloud platforms; Python; NLP/DL; UiPath/Power Automate; Bachelor's in CS/Data Science; Master’s/PhD preferred.
Python, scikit-learn, TensorFlow, PyTorch, UiPath, Power Automate, APIs, Azure, AWS, GCP, Databricks, Airflow, NLP, Deep Learning, Computer Vision
1mo
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Lead SCADA & Automation Engineer 1 - Grid
Indianapolis, Indiana, United States
$117k-$180k/yr HybridFull Time
8+ YOEBachelor's in Electrical/Electronic/Telecommunications/Computer Systems Engineering; 8 years design/implementation/troubleshooting substation SCADA and communications; experience with SEL/Novatech/GE RTUs; DNP/Modbus/IEC 61850; travel up to 30%; MS Office; Python and network config experience.
SCADA, RTU, SEL, Novatech, GE RTU, HMI, SCADA Diagram Builder, Inkscape, Wonderware, Cisco, Siemens Ruggedcom, SEL, DNP, Modbus, IEC 61850, TCP/IP, UDP, MS Office, Python
2w
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Senior DevOps Engineer
Indianapolis or Burnaby or Mesa
HybridFull Time
5+ YOE5+ years in Infrastructure as Code and software release pipelines; Bachelor's in Engineering or Computer Science; strong automation and cloud skills.
Azure DevOps, YAML, Terraform, ARM, Bicep, PowerShell, Python, Monitoring, IT Security
HiringCafe market data
Python Developer Jobs market signals in Columbus, IN, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
98
Hiring companies
48
Fresh sample
54% new in 30d
Salary visibility
51% show pay
Companies appearing in this market
Eli Lilly and CompanyHuntingtonLiberty MutualTerran RoboticsV2XCALRegionalCroweElevance Health
Work location mix in visible results
Hybrid: 35Onsite: 34Remote: 5