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Python Developer Jobs in Foothill Ranch, CA, US
1,600+ python developer jobs from 420+ companies hiring in Foothill Ranch, CA, US.
3w
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AI Agent Builder
Carlsbad or Scottsdale or Austin or Charlotte or Chicago
RemoteFull Time
5+ years Python/JSON/JavaScript; experience with AI platforms and APIs; web and data skills; knowledge of MarTech is a plus.
Python, JSON, JavaScript, APIs, Webhooks, HTML, CSS, SQL, Firebase, Power Automate, Copilot, Claude, Codex, n8n
3w
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Phantom Works Software Lead
Berkeley or Arlington or Mesa or El Segundo or Colorado Springs
$184k-$286k/yr OnsiteFull Time
5+ YOE5+ MgmtBachelor’s degree; 5+ years in leading software/architecture; Agile lead; DevSecOps and CI/CD experience; scripting (Python/Bash).
Git, Jenkins, CI/CD, Config Management, Python, Bash, JIRA, Collaborator, Beyond Compare, VersionOne
3w
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Senior Technical Artist: Procedural Art
Carlsbad or Leeds or Oakville
$105k-$140k/yr OnsiteFull Time
5+ YOE5+ years as Technical Artist/Tools Programmer; expert in photogrammetry workflows; Python; build systems; DCC tools; ML pipelines.
Houdini, Zbrush, Agisoft, Metashape, Python, Jenkins, Airflow, Celery
3w
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R&D Associate - Consumable Development
Irvine, California, United States
$62k-$65k/yr OnsiteFull Time
DOE experience; SolidWorks CAD; wet-lab hands-on; data analysis (Python/JMP); cross-functional collaboration.
SolidWorks, CAD, Python, JMP, 3D printing, CNC machining
1w
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Game Research & Development Intern, Engine Research
Los Angeles, California, United States
$28-$60/hr OnsiteFull Time
Strong coding skills in C++, Python, TensorFlow/Torch; knowledge of calculus, linear algebra; good communication and responsibility.
C++, Python, TensorFlow, PyTorch
3w
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Sr. Professional, Software Engineering
Irvine or Dallas
$130k-$160k/yr RemoteFull Time
8+ YOE8+ years software engineering; strong Snowflake, Databricks, Python, SQL; cloud platforms; large-scale production systems; mentoring; AI/ML data capabilities.
Snowflake, Databricks, Apache Spark, Python, SQL, Cloud Platforms, Airflow, Dagster, Terraform, Tableau, Looker, Kafka, Pub/Sub
3w
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AI Creative Technologist
Los Angeles, California, United States
$160k-$180k/yr OnsiteFull Time
Portfolio required; AI-native work; strong experience with AI tools (ComfyUI), Python; production and pipeline expertise; ability to travel up to 25%; excellent communication.
ComfyUI, Python, After Effects, Premiere, Houdini, Nuke, DaVinci Resolve, Maya, Blender, Unreal Engine, Unity
3w
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Data Scientist II
Irvine or Remote
$83k-$127k/yr HybridFull Time
2+ YOE2–5+ years of data science experience; Bachelor's in CS/DS/Engineering/Math; production ML deployment; cloud platforms (Azure/AWS); Python and SQL; strong communication.
Python, SQL, Azure Machine Learning, AWS, SageMaker, LLMs, NLP
4d
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Simulation Platform Partner Product Owner, Architect
Lake Forest or Houston or Philadelphia
$142k-$271k/yr HybridFull Time
7+ YOE7+ years in process industry; MS in Chemical Engineering; domain expert in chemical process simulation; experience with AVEVA Process Simulation or similar; Python coding ability; agile experience.
Python, C#, C++
3w
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Research Programmer I
Los Angeles, California, United States
$46-$51/hr RemoteFull Time
3+ YOEMS in CS/Statistics/Mathematics; strong TypeScript/JavaScript and Python; 5 years React; 3 years Django/Flask/FastAPI; experience with MySQL/PostgreSQL; Git/GitHub; ability to work independently.
Python, TypeScript, JavaScript, React, Django, Flask, FastAPI, MySQL, PostgreSQL, Git, GitHub, Highcharts
1mo
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Software Intern
Irvine, California, United States
$25-$40/hr HybridFull Time, Internship
2+ YOEUndergraduate student (rising senior in Summer 2026) pursuing CS/CE/Math or related field; strong communicator; experience with Python/JavaScript/C#/C++; REST APIs; JSON; cloud basics; excellent interpersonal skills.
Python, JavaScript, C#, C++, REST, JSON, AWS, GCP, Azure, Google Workspace
2mo
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Agentic AI Architect
Irvine, California, United States
$159k-$270k/yr OnsiteFull Time
10+ YOE10+ years software engineering and AI/ML systems; 5-7 years in architecting distributed AI systems; deep agentic AI, LLMs; Python and ML libraries; software architecture; MLOps/LLMOps; data engineering and cloud platforms.
Python, TensorFlow, PyTorch, scikit-learn, Hugging Face Transformers, LangChain, AutoGen, CrewAI, LlamaIndex, Google Vertex AI, Microsoft Semantic Kernel, APIs, microservices, MLOps, LLMOps, data pipelines, vector databases, knowledge graphs, cloud platforms
3w
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Product Development Scientist
Irvine, California, United States
$77k-$120k/yr OnsiteFull Time
3+ YOEMaster’s with 3+ years or PhD with 1+ year; expertise in NGS, PCR-based assays; molecular biology (PCR/MSP), DNA extraction; FDA QSR/ISO knowledge; data analysis with R/Python; strong communication.
NGS, PCR, MSP, DNA extraction, R, Python
1w
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Research Technician
Claremont, California, United States
$20-$22/hr OnsiteFull Time
Bachelor’s degree in physics or related field; strong communication; Python/LaTeX; advise undergraduates; Workday experience a plus.
Python, LaTeX, Microsoft Office, Scientific computing software
3w
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Post-Baccalaureate Research Assistant, Rosenberg HuMan Lab
Claremont, California, United States
$20/hr OnsitePart Time
BA in neuroscience or psychology; proficiency with Python or R; part-time, 5-15 hours/week; temporary, non-benefits-eligible; California resident.
Python, R, Excel
1mo
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Research Scientist
Costa Mesa, California, United States
$125k-$150k/yr HybridFull Time
5+ YOEPhD in neuroscience or related quantitative field; experience with neuroimaging research and machine learning; proficient in Python/MATLAB/R; familiarity with SPM, FSL, AFNI or Nilearn.
Python, MATLAB, R, SPM, FSL, AFNI, Nilearn
1mo
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Quantitative Research Analyst - Client Solutions & Analytics
Newport Beach, California, United States
$205k-$230k/yr OnsiteFull Time
1+ YOE1-3 years asset management or research experience; PhD desirable; strong quantitative background; programming in Python/MATLAB/C++; strong analytical and presentation skills.
Python, MATLAB, C++
1mo
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Research Associate
Newport Beach, California, United States
$80k-$110k/yr HybridFull Time
1+ YOEBachelor’s degree in finance/real estate/economics; 1-3 years in financial research; strong financial modeling and Excel; CFA interest; SQL/Python a plus.
SQL, Python, Microsoft Excel
6d
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Psychometrician
Torrance, California, United States
$110k-$125k/yr HybridFull Time
3+ YOEMaster's in psychometrics or related quantitative field; 3+ years in psychometrics; proficiency in R/SPSS; Python; experience with AI tools; strong data analysis and project management skills.
R, SPSS, Python, Claude Code, Copilot, LLM scripting
4d
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Senior Scientist II/Principal Research Scientist I - Translational Program Science
Irvine, California, United States
$110k-$209k/yr OnsiteFull Time
4+ YOEPhD with 4+ years, or Master’s with 10+ years, or Bachelor’s with 12+ years; ophthalmology experience; programming in Python or R; in vivo preclinical experience; cross-functional collaboration; strong scientific communication.
Python, R, Computational Biology
2mo
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Principal Information Systems Analyst - Lead EDI Developer (N387)
Los Angeles, California, United States
$48-$69/hr HybridFull Time
4+ YOEBachelor's in CS/Info Systems + 4 years IT experience; or senior IS analyst with required years; CA driver license; Live Scan clearance.
Python, SQL, ANSI X12, HIPAA, Cloud platforms, Git
1w
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Business Data Insights Analyst
Los Angeles, California, United States
$100k-$150k/yr HybridFull Time
5+ YOE5+ years BI and dashboard development; 2+ years with Sigma/Tableau; SQL/Python/R; knowledge of digital advertising metrics.
Snowflake, DBT, Sigma Computing, Tableau, SQL, Python, R
3w
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Project Assistant
Marina Del Rey, California, United States
$26-$27/hr OnsiteFull Time
1+ YOEBachelor's or master's in engineering, computer science, math, statistics, neuroscience, data science, or related field; image analysis experience; programming in Matlab, Python, R, C++, shell; familiarity with FSL/FreeSurfer; knowledge of statistics or genetics is a plus.
FSL, FreeSurfer, Matlab, Python, R, C++, Shell scripting, SPM
1w
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Student Research Assistant - Industrial and Manufacturing Engineering #705037701
Pomona, California, United States
$18-$20/hr OnsitePart Time
Pursuing an undergraduate or graduate degree in science or engineering; US citizen or green card holder; Python, ML, optimization, CFD (ANSYS); literature review; strong English communication; reliable; team-oriented; proficient in MS Office and Canvas.
Python, Machine Learning, ANSYS CFD, Microsoft Word, Excel, PowerPoint, Canvas
23h
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Senior Technical Lead, AI & Automation
Glendale, California, United States
$140k-$185k/yr HybridFull Time
7+ YOE7+ years Python development; experience with LLMs and AI frameworks; cloud AI workloads; strong system design; aware of AI safety and ethics.
Python, LLMs, LangChain, LlamaIndex, RAG, Vector databases, GCP, AWS, Azure, Docker, Kubernetes, React, Next.js
2mo
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Intern, Advanced Computer Graphics Research
Culver City, California, United States
$50/hr OnsiteInternship, Full Time
Ph.D. candidate or post-doctoral researcher with strong background in human-centric Generative AI and photo-realistic 3D graphics; proficient in Python/Matlab/C/C++; familiar with Unreal Engine, Unity, Maya, Blender, or similar tools; excellent analytical skills; authorized to work in the USA.
Python, Matlab, C/C++, Unreal Engine, Unity, Maya, Blender, Marmoset
1mo
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Associate Director, Media Analytics
Los Angeles, California, United States
$130k-$160k/yr HybridFull Time
Senior analytics role requiring SQL and data pipeline development, cloud data platforms, Python for data processing, and strong communication to translate data into insights.
SQL, ETL/ELT, Python, Databricks, GCP, Tableau, Datorama
3w
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Student Assistant - CA DMV Customer Services Division- Information Technology - Hybrid
Sacramento or Fresno or Riverside
$17-$21/hr HybridPart Time, Temporary
College student; basic web development and data analysis knowledge; HTML/CSS/JavaScript; Python; NLP interest; bilingual in Spanish and English; willing to work in a hybrid schedule.
HTML, CSS, JavaScript, Python, Jupyter, LangChain, Bedrock, Pinecone, FAISS
1d
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Business Intelligence - Senior Programmer
Minneapolis or Charlotte or Irvine or Cincinnati or Owensboro or Owensboro
$105k-$124k/yr HybridFull Time
6+ YOEBachelor’s degree or equivalent; 6+ years in development; strong SQL, Python/C#, Power Platform, Tableau/Power BI; ETL/ELT; Azure; APIs; hybrid schedule.
SQL, Python, C#, Power Platform, Tableau, Power BI, ETL/ELT, Azure, APIs
2w
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LIMS Support Specialist
Huntington Beach, California, United States
OnsiteFull Time
Bachelor’s degree or related experience; experience supporting enterprise systems (SaaS, custom, or hybrid); strong troubleshooting across software, hardware, and network; knowledge of .NET, Python, VBA, Java; SQL; Microsoft Power Platform; excellent communication; team collaboration; willingness to work outside hours when needed.
Programming: .NET, Programming: Python, Programming: VBA, Programming: Java, SQL, Microsoft Power Platform, Power Automate, Power BI
2mo
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Senior Model Risk Manager
Pasadena, California, United States
$150k-$200k/yr OnsiteFull Time
10+ YOEMaster’s in quantitative field; strong math, statistics; Treasury/ALM knowledge; SQL, R, Python; MS Office; 10+ years in statistics, model development/validation; Treasury models preferred.
SQL, R, Python, MS Office
1mo
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Senior Scientist, Clinical Data
Pasadena or San Diego
$140k-$170k/yr OnsiteAll Commitments Available
3+ YOEPhD in biological/biomedical/medical field; 3+ years in biotech/pharma data analysis; strong clinical data analysis and medical writing; experience with early-stage development; SAS/R/Python experience.
SAS, R, Python, Data Visualization
1mo
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Principal Technical Artist (Apex Legends)
Vancouver or Los Angeles or Madison
HybridFull Time
8+ YOE8+ years game development; design/implement tools and workflows; programming in Python, MEL, or C#; UI frameworks (Qt); experience with Maya and Adobe Creative Cloud; strong content creation workflow interest.
Python, MEL, C#, Qt, Autodesk Maya, Adobe Creative Cloud, DCC
1mo
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INFORMATION TECHNOLOGY MANAGER - APPLICATIONS AND ANALYTICS
Torrance, California, United States
$12k-$18k/mo OnsiteFull Time
7+ YOE3+ MgmtBachelor's degree in computer science or related field; 7+ years enterprise applications development and support; 3+ years supervisory/leadership; experience with JavaScript, Python, .NET; REST APIs; SQL Server; Power Platform; SharePoint; GIS; government experience preferred.
JavaScript, Python, .NET, REST API, Microsoft SQL Server, Microsoft Power Platform, SharePoint, GIS
3w
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Intern, Automation & AI Development
Tustin, California, United States
$20/hr OnsiteInternship
Currently pursuing a degree in biotechnology/biology/biochemistry/chemical engineering/bioengineering or related field; Excel data handling; interest in AI/ML; quick learner of new tools; strong analytical and communication skills; available for 10-week, full-time internship at the Tustin, CA facility.
Excel, Python, Java, C++, AI/ML tools
1mo
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Advisory Analyst, Technology Transaction - Software: Experienced Consultant
Chicago or Boston or Dallas or Los Angeles or Minneapolis or New York or San Francisco or Seattle
$88k-$120k/yr HybridFull Time
2+ YOEBachelor’s degree or equivalent; 2-4+ years software development experience; strong SDLC, OO design (C#, Java, Python); Agile/Lean; ability to lead requirements; travel 20-30%; hybrid in US offices; authorized to work in the US without sponsorship
C#, Java, Python, SDLC, Agile, Agentic AI/LLMs
1mo
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Water Quality Science Internship
Los Angeles, California, United States
$25/hr HybridInternship, Full Time
Internship supporting water quality monitoring, data entry, analysis, and GIS; fieldwork, project work, and reporting.
Microsoft Office, Google Workspace, ArcGIS, R, Python
2w
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Senior Scientist
Riverside or Aguadilla
OnsiteFull Time
10+ YOESenior Scientist with 10+ years experience in C4I, AMOSS, ISR; DoD/DHS environment exposure; travel; Secret clearance.
Python, R, Data visualization tools, Microsoft Office
4w
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Director, Computational Biology
Carlsbad or Boston or Remote
$200k-$250k/yr HybridFull Time
8+ YOE1+ MgmtPhD in computational biology or related field; 8+ years experience; leadership experience; multi-omics expertise; strong programming.
Python, R, Bash, Docker, Nextflow, AWS
1w
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Workplace Research Lead
Chicago or Los Angeles or Arlington or San Francisco or Seattle or Boston or San Jose
OnsiteFull Time
3+ YOEPhD preferred or Master’s in I/O psychology/related field; 3+ years applied research in industry; experience with mixed methods, client-facing work, and AI tools.
Power BI, Python, R
HiringCafe market data
Python Developer Jobs market signals in Foothill Ranch, CA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
1,600+
Hiring companies
420+
Fresh sample
68% new in 30d
Salary visibility
85% show pay
Companies appearing in this market
University of Southern CaliforniaWest MonroeCal Poly Pomona FoundationCanon U.S.A.Rockstar GamesCotalityEast West BankElectronic Arts
Work location mix in visible results
Onsite: 31Hybrid: 25Remote: 3