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Python Developer Jobs in Jacobus, PA, US

470+ python developer jobs from 170+ companies hiring in Jacobus, PA, US.

472 jobs- Jacobus • 50 miles
1mo
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CNO Reverse Engineer 2
Hanover or Fort Meade
$170k-$200k/yr OnsiteFull Time
T-Rex Solutions
T-Rex Solutions: IT modernization and cybersecurity for the federal government.
6+ YOEReverse engineering of hardware/software; multiple programming languages; TS/SCI w/Poly; onsite in Hanover, MD; Bachelor's/Master's with years of experience.
IDA Pro, Ghidra, OllyDbg, WinDbg, Subversion, Git, C, C++, Java, Python, C#, Perl
2mo
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RF/uW Solutions Engineer
Columbia, Maryland, United States
OnsiteFull Time
Keysight Technologies
Keysight TechnologiesNew York Stock Exchange: KEYS: Manufactures hardware and software for electronic test and measurement.
4+ YOEBSEE required; TS/SCI with Poly; US citizen; 4+ years RF/microwave experience; strong communication; field role; travel 10-25%; ability to transport test equipment.
C, C#, Python, Matlab
1mo
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AI Research Computing Infrastructure Engineer
Frederick, Maryland, United States
$124k-$207k/yr OnsiteFull Time
Leidos Biomedical Research
Leidos Biomedical Research: Operates the Frederick National Laboratory for Cancer Research.
8+ YOEBachelor’s degree or 4 years experience; 8+ years related experience; Linux systems engineering; container orchestration; scripting; IaC tooling; performance tuning; security clearance ability.
Kubernetes, Nomad, Run:AI, Python, Bash, Go, Terraform, Ansible, Packer, Pytorch, Ray, Airflow, Dagster, Kubeflow, Prefect, Dagster, Kubeflow, MLFlow
2w
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Controls/Automation Engineer Job (Lancaster, PA, US, 17603)
Lancaster, Pennsylvania, United States
$95k-$115k/yr OnsiteFull Time
Armstrong World Industries
Armstrong World IndustriesNYSE: AWI: Designs and manufactures interior ceiling and wall systems.
5+ YOEExperience in controls and automation within manufacturing; AI/data analytics knowledge; 5–10 years; travel up to 25%; bachelor's in a related field; Lean/Six Sigma; strong communication.
Python, SQL, Power BI, Minitab, ANSYS, GaBi, Odeon, 3D modeling
1w
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IT Infrastructure & Cloud Engineer (Phoenix, AZ, US, 85085)
Phoenix or Flagstaff or Elkton
$98k-$143k/yr HybridFull Time
W. L. Gore & Associates
W. L. Gore & Associates: Develops high-performance fluoropolymer products for medical, textile, and industrial use.
3+ YOE3+ years IT infrastructure and cloud administration; Azure design/implementation focus; IaC experience; scripting and CI/CD skills.
Ansible, ARM/Bicep, Terraform, CloudFormation/CDK, PowerShell, Python, Azure CLI, Git, GitHub Actions
1mo
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System Test Intern
Edgewood, Maryland, United States
$15-$35/hr OnsiteInternship
Smiths Group
Smiths GroupLondon Stock Exchange: SMIN: Global engineering of mission-critical components for industrial markets.
0+ YOEUndergrad in process or completed; 0 years experience; familiar with Windows, Linux, virtualization, and Python.
Windows, Linux, Python, Virtualization
2mo
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AI Researcher Intern DU26
Baltimore, Maryland, United States
$15/hr OnsiteMultiple Commitments Available
Davis Unlimited Information Technologies
Davis Unlimited Information Technologies: Provides IT consulting and systems engineering services to government agencies.
0+ YOEPursuing Bachelor's or Master's in CS, Software Engineering, Applied Mathematics, or related field; GPA 3.0+; strong Python/Java/C++/JavaScript experience; familiarity with deep learning tools; able to work >=30 hours/week for 8 weeks.
Python, Java, JavaScript, TypeScript, C++, PyTorch, TensorFlow, Codex, Claude Code, Gemini
1mo
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Part-time Research Assistant
Hershey, Pennsylvania, United States
OnsitePart Time
Penn State University
Penn State University: Provides higher education and conducts extensive academic research programs.
0+ YOEGraduate student intern with Python and machine learning experience; strong analytical and communication skills; interest in AI in healthcare.
Python, Machine Learning
1w
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PostDoc Neuroscience Computational Biology
Spring House, Pennsylvania, United States
$79k-$128k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
PhD in a quantitative field; strong ML experience; proficient in R/Python; multi-omics integration; excellent communication; independent and collaborative work.
Python, R, SQL, Bash, High-Performance Computing
1w
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Sr. Scientist, Preclinical Dev.
West Point, Pennsylvania, United States
$117k-$184k/yr OnsiteFull Time
Merck & Co.
Merck & Co.NYSE: MRK: Produces prescription medicines, vaccines, and animal health products.
2+ YOEExperience in high-throughput process development for large biomolecules; advanced degree in engineering or bio/chemical sciences; 2+ years of process development; programming and automation skills; downstream chromatography/filtration knowledge.
Python, VB/VBA, C++, Matlab, Robotic systems, High-throughput screening, HPLC, Membrane filtration
2w
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Credit Model Development Quantitative Analyst II - Small Business and Home Secured (Hybrid - see potential locations in job description)
Buffalo or Bridgeport or Wilmington or Baltimore or Washington or New York City
$72k-$119k/yr HybridFull Time
M&T Bank
M&T BankNYSE: MTB: Provides retail, commercial, and wealth management banking services.
1+ YOEBachelor’s degree and at least 1 year of quantitative modeling experience; strong Python, SQL; model development and data management skills.
Python, SQL, SAS, R
2w
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Credit Model Development Quantitative Analyst II - Small Business and Home Secured (Hybrid - see potential locations in job description)
Buffalo or Bridgeport or Wilmington or Baltimore or Washington or New York
$72k-$119k/yr HybridFull Time
M&T Bank
M&T BankNYSE: MTB: Provides retail, commercial, and institutional banking and trust services.
1+ YOEBachelor’s degree plus 1 year quantitative modeling experience or 5 years education/work; strong Python; SQL; SAS/R; model development in credit risk.
Python, SQL, SAS, R
1mo
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Network-based Anomaly Detection Researcher (5673)
Aberdeen, Maryland, United States
$90k-$120k/yr OnsiteFull Time
Three Saints Bay
Three Saints Bay: Provides technical and administrative services to federal government agencies.
PhD in Engineering, Network Science, Neuroscience, CS, Statistics (MS considered); strong research in networks; publications preferred; proficient in Python/SQL/Julia; graph DBs or big data tools; multi-project management; US citizenship with security clearance.
Python, SQL, Julia, Neo4j, TigerGraph, Amazon Neptune, Apache Spark, Scala
1mo
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Genomics Computational Systems Biologist
Frederick, Maryland, United States
$140k-$160k/yr OnsiteFull Time
Cape Fox Federal Integrators
Cape Fox Federal Integrators: Provides government agencies with professional, technical, and training services.
5+ YOEMaster's degree in biomedical science, bioinformatics, math, or computer science; 5+ years experience; HPC, Linux, scripting; NGS data analysis; Python/Perl/Shell/R/C++/Java; U.S. citizen; Tier 1 background check; travel.
HPC, Linux, Python, Perl, Shell, R, C++, Java, Next Generation Sequencing, Oxford Nanopore, Illumina, Pipeline automation, Bioinformatics tools
1d
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Sr Data Scientist
Baltimore or De Pere or Chicago or Kennett Square or Houston or Warrenville
$131k-$145k/yr HybridFull Time
Constellation Energy
Constellation EnergyNASDAQ: CEG: Produces carbon-free electricity and supplies energy to customers.
5+ YOEPython-based data science, ML model development, generative AI, and end-to-end pipelines; Masters/PhD in quantitative field; nuclear/power data domain experience; strong ML/ statistics; proficient in Python/R/Scala/SQL.
Python, R, Scala, SQL, Spark, Hadoop, Databricks, Azure Data Factory
1mo
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Network-based Anomaly Detection Researcher (5673)
Aberdeen, Maryland, United States
$90k-$120k/yr OnsiteFull Time
Three Saints Bay
Three Saints Bay: Provides professional and technical services to federal government agencies.
PhD in Engineering, Network Science, Neuroscience, Computer Science, Statistics, or related field; strong research on complex networks; publications preferred; programming in Python/SQL/Julia; graph databases or big data experience; US citizenship for clearance; ability to manage multiple projects.
Python, SQL, Julia, Neo4j, TigerGraph, Amazon Neptune, Apache Spark, Scala
1mo
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Research Scientist III
Columbia or United States
$90k-$123k/yr HybridFull Time
UL Research Institutes
UL Research Institutes: Performs independent research to advance global public safety science.
8+ YOEPhD or Masters with relevant experience; strong data science, GIS, Python/R; experience with large spatial/temporal data; risk analysis and model development; proficient communicator and collaborator.
Python, R, GitHub, Pandas, ArcGIS, QGIS, ArcGIS Pro, ArcGIS Online, AWS
1d
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GIS Analyst/Sr. GIS Programmer
Towson, Maryland, United States
HybridFull Time
TriTech Enterprise Systems
TriTech Enterprise Systems: Provides IT consulting and enterprise systems for government agencies
5+ YOEFive+ years in GIS app development with J2EE/.NET/JavaScript/Python; ESRI ArcGIS; SQL/SSRS; bachelor’s in Business or Computer Science or related field; background check required.
ArcGIS Server, ArcGIS APIs, ArcGIS JavaScript API, ArcGIS Web AppBuilder, Collector, ArcSDE, ArcGIS Mobile, SQL, SSRS, C#, Python, JavaScript, HTML, J2EE, .NET, Visual Studio
1w
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Director, Analytics
Columbia, Maryland, United States
$167k-$191k/yr RemoteFull Time, Contract
Dentsu
DentsuTokyo Stock Exchange: 4324: Providing global advertising, digital marketing, and media communications services.
2+ YOELead analytics teams; develop and deliver marketing analytics; proficient in R/Python/SAS/SQL; 2+ years experience; Master’s in quantitative field; remote and travel up to 20%; salary range provided.
SAS, R, SQL, Python, Tableau, MicroStrategy, Adobe Analytics, Google Analytics, DMP
2mo
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CNO Analyst/Programmer Level 1
Annapolis Junction or Hanover
$135k-$150k/yr OnsiteFull Time
Adventure Technology Services
Adventure Technology Services: Providing specialized IT services and engineering for government agencies.
TS/SCI with Polygraph; Bachelor's in CS/IS/Network Engineering or equivalent; IAT Level 2 Certification; multiple experience options for education.
C, C++, Java, Perl, Python, Assembly, Visual Studio, .NET, UNIX, Makefiles
2mo
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Web and Digital Interface Designer (contingent 034)
Huntsville or Aberdeen
HybridFull Time
Systems Products and Solutions
Systems Products and Solutions: Provides logistical and technical readiness solutions for defense agencies.
10+ YOESecret clearance required; 10+ years in web design; BA/BS in CS/Design; strong responsive design, UX, HTML/CSS/JS; DoD cybersecurity and accessibility experience.
HTML5, CSS, JavaScript, Python, PHP, SQL, Adobe Creative Suite, Photoshop, Dreamweaver, PowerPoint, XML, Unix, Windows
1w
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National Security Solutions (NSS) – Software Engineering Internship
Columbia, Maryland, United States
OnsiteMultiple Commitments Available
KBR
KBRNYSE: KBR: Provides engineering, technology, and professional services for global markets.
Pursuing a 4-year degree in CS/CE/engineering; ability to obtain TS/SCI clearance; write clean code; Agile/Scrum experience; internship.
Python, MATLAB, Autodesk Inventor, Autodesk Vault, SharePoint, JIRA
2w
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CNO Analyst Programmer, Level 2 (AE26041103)
Hanover, Maryland, United States
$144k-$156k/yr OnsiteFull Time
Advantage Engineering & IT Solutions
Advantage Engineering & IT Solutions: Provides technical engineering and IT services for government agencies.
8+ YOE8 years of relevant programming experience; master degree substitute 2 years; requires a Bachelor's degree.
C, C++, Java, Perl, Python, Assembly, UNIX, Visual Studio, .NET
6d
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Consumer Product Strategy Analyst II/III – Analytics & Model Development
Charlotte or Hunt Valley or Las Vegas or Utica
$82k-$126k/yr HybridFull Time
Bank of America
Bank of AmericaNYSE: BAC: Provides global banking, investment, and wealth management services.
1+ YOE1+ years SQL, Tableau; Python; advanced Excel; strong communication; multi-project handling; data analysis and reporting.
SQL, Tableau, Python, Excel, Alteryx, SAS, SSMS, Oracle, Hadoop, Teradata
3w
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Manager AI Excellence (Frederick, MD, US, 21703)
Frederick, Maryland, United States
OnsiteFull Time
Leonardo DRS
Leonardo DRSNASDAQ: DRS: Manufactures advanced electronic systems for defense and military applications.
Bachelor’s in engineering, computer science, data science, or related field; experience leading AI initiatives; strong program management, communication, and cross-functional collaboration.
Python, Data Analytics
4w
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Entomology and Biostatistics Intern (Summer 2026)
Baltimore or Anne Arundel County or Montgomery County
$25/hr HybridInternship, Full Time
Vectech
Vectech: AI-powered insect identification and vector surveillance technologies.
Degree in entomology/biological/environmental sciences or relevant coursework; statistics/geographical analysis exposure; comfortable outdoors; valid driver's license; able to work in lab and field.
Excel, Google Sheets, R, Python, ArcGIS
3w
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Post Doctoral Researcher - HRC0015382
Baltimore, Maryland, United States
OnsiteFull Time
Association of Universities for Research in Astronomy
Association of Universities for Research in Astronomy: Manages astronomical observatories and research facilities for NASA and NSF
Postdoctoral researcher position in astronomy-related research; full-time; located in Baltimore, MD.
Python, MATLAB, R, LaTeX
3w
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Program Associate
Harrisburg, Pennsylvania, United States
OnsiteFull Time
University of Arkansas System Division of Agriculture
University of Arkansas System Division of Agriculture: Conducts agricultural research and provides community outreach services statewide.
3+ YOEBachelor’s degree in a related field plus 3 years’ experience, or a related Master’s degree; field-based agronomic research experience; data management; willingness to travel statewide.
Excel, R, Python, Geospatial tools, UAV platforms
3w
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Program Associate
Harrisburg, Pennsylvania, United States
OnsiteFull Time
University of Arkansas System
University of Arkansas System: Public university system providing higher education and clinical research.
3+ YOEBachelor’s degree in Agronomy/Soil Science/Crop Science or related field with 3 years of experience, or related Master’s degree; field-based agronomic research experience; soil/plant sampling; willingness to travel statewide.
Excel, R, Python, UAV, Proximal sensors, Data loggers, Microsoft Word, GIS
2w
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Biologist (Genomics) (50865)
Baltimore, Maryland, United States
$70k-$140k/yr OnsiteFull Time
GAP Solutions
GAP Solutions: Providing professional services and mission support to federal agencies.
2+ YOEMasters in Biology or related field; 2+ years experience; R and scripting; QC and data visualization; familiarity with genomic data formats.
R, Python, Bash
1w
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Biologist
Baltimore, Maryland, United States
$100k/yr OnsiteFull Time
Nextonic Solutions
Nextonic Solutions: Provides scientific and technology development services to federal agencies.
1+ YOEFull-time biologist with 1-3 years experience; master's in biology; strong R and scripting skills; QC and data visualization experience; familiarity with genomic data formats.
R, Python, Bash, QC pipelines, DNA methylation, Genomic data formats
5d
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Data Scientist
Denver or Washington or Boston or Woodlawn or Philadelphia
$82k-$133k/yr HybridFull Time
Centers for Medicare & Medicaid Services
Centers for Medicare & Medicaid Services: Administers federal health insurance programs including Medicare and Medicaid.
1+ YOEExperience with healthcare data analysis using R/SAS/SPSS; develop reports and dashboards; communicate results clearly.
SAS, R, SPSS, STATA, Python
2mo
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Application Integration Specialist
Lancaster or Allentown or Chambersburg or Reading or York or Mechanicsburg or Exton
$75k-$85k/yr HybridFull Time
RKL
RKL: Provides professional accounting, tax, and business advisory services.
3+ YOEDesign, develop, and maintain secure application integrations using APIs, AI, and automation; collaborate with stakeholders; ensure security; document and upgrade systems.
PowerShell, Power Automate, APIs, Azure OpenAI, Private AI, Power BI, Python, SQL, Smartsheet
1mo
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Linux System Administrator
Welcome, Maryland, United States
$75k-$102k/yr OnsiteFull Time
Space Ground System Solutions
Space Ground System Solutions: Provides engineering services for satellite ground systems and space missions.
2+ YOEUS citizen; TS/SCI eligible within 18 months; BS in CS/Engineering or related field; 2+ years software development; Linux/Red Hat proficiency; scripting; networking; DoD 8570 IAT2; security clearance.
Linux, Red Hat, C/C++, Python, PERL, Shell Scripting, GIT, Mercurial, TCP/IP

HiringCafe market data

Python Developer Jobs market signals in Jacobus, PA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
470+
Hiring companies
170+
Fresh sample
59% new in 30d
Salary visibility
73% show pay

Companies appearing in this market

M&T BankPenn State UniversitySmiths GroupThree Saints BayUL Research InstitutesAdvantage Engineering & IT SolutionsAdventure Technology ServicesArmstrong World Industries

Work location mix in visible results

Onsite: 23Hybrid: 13Remote: 1

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