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Python Developer Jobs in Middletown, DE, US
770+ python developer jobs from 250+ companies hiring in Middletown, DE, US.
2mo
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Sr Systems Engineer SRE
Wilmington or Urbandale or Irving or Manassas
HybridFull Time
5+ YOE5+ years IT/infrastructure, 5+ years SRE/DevOps, scripting, observability, cloud/hybrid, Kubernetes, GitOps, automation, security best practices
Dynatrace, Datadog, ELK Stack, Kubernetes, Helm, Prometheus, GitOps, GitHub Actions, Terraform, Ansible, Chef, Puppet, Python, Go, Bash, JavaScript
1mo
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Senior Director, Software Engineering
Philadelphia or Alexandria or Ann Arbor
HybridFull Time
10+ YOE5+ MgmtBachelor's in CS or related; 10+ years leadership; 10+ years software development; strong Java and Python.
Java, Python, Angular, Talend, Databricks, Spark, AWS, PostgreSQL, MySQL, Oracle, XML, XSLT, REST, SOAP, NodeJS
5d
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Lead EHV Engineer 2 - Grid
Wilmington, Delaware, United States
$132k-$205k/yr HybridFull Time
10+ YOEBSEE with power systems focus; 10+ years protection/control/telecom for HV substations; 3+ years 500kV/765kV design; strong reporting, coordination, and MS Office skills; ability to lead projects; not sponsoring work authorization.
AutoCAD, MicroStation, Bentley Substation, BlueBeam, Python, MATLAB, Excel, SDS design software
2mo
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Eng Sr Prin II - Test
Annapolis Junction, Maryland, United States
$150k-$254k/yr OnsiteFull Time
10+ YOEJava expertise; broad experience with Java/JEE, Python, C/C++, SQL, SOAP/WSDL; UI development; cryptography knowledge; Windows/Linux; web services; strong software principles; effective communication; independent thinker.
Java, Python, C/C++, SQL, SOAP/WSDL, PERL, PowerShell, Eclipse, Postgres, Oracle, Jenkins, JSON, HTML, XML, XSLT
3w
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Manager Procurement Principal Cost Engineer
West Chester or Cincinnati or Raritan or Irvine
$102k-$177k/yr HybridFull Time
10+ YOE10+ years in electronics cost engineering with EMS experience; bachelor's degree required; strong cost modeling and negotiation skills.
Microsoft Excel, PLM, ERP, BOM management, EDA tools, SQL, Python, Tableau, Power BI
3d
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Network Day 2 Operations Engineer
Maryland City, Maryland, United States
HybridFull Time
5+ YOE5-10 years in enterprise network operations; routing/switching, firewall management on Cisco/Palo Alto; SSL/TLS inspection; ITSM tools; scripting; network automation; on-call flexibility.
Cisco Routers, Cisco Switches, Cisco ASA, Palo Alto PAN-OS, Cisco VPN AnyConnect, Zscaler ZIA/ZPA, HPE Aruba, Imperva WAF, F5 BIG-IP, Infoblox DDI, Git, Python, Ansible, Terraform, NETCONF/YANG, NAPALM, Netmiko
1mo
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Actuarial Data Engineer - Centralized Data Solutions (Radnor, PA, US)
Radnor, Pennsylvania, United States
$97k-$176k/yr HybridFull Time
5+ YOE5–7+ years data engineering/actuarial data experience; Dataiku proficiency; strong communication; ETL/ELT and data quality expertise.
Dataiku, Python, SQL, Spark, AWS, Tableau
1w
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IT Infrastructure & Cloud Engineer (Phoenix, AZ, US, 85085)
Phoenix or Flagstaff or Elkton
$98k-$143k/yr HybridFull Time
3+ YOE3+ years IT infrastructure and cloud administration; Azure design/implementation focus; IaC experience; scripting and CI/CD skills.
Ansible, ARM/Bicep, Terraform, CloudFormation/CDK, PowerShell, Python, Azure CLI, Git, GitHub Actions
2mo
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Information Protection Advisor
St. Louis or Bloomfield or Philadelphia
OnsiteFull Time
7+ YOE7+ years in application development; Node.js/JavaScript, Python, RESTful APIs, Oracle, MySQL; Linux, shell scripting; architecture discussions; strong problem solving and collaboration.
Node.js, JavaScript, Python, REST, Oracle, MySQL, Linux, Shell scripting, Docker, Jenkins, Okta
1mo
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Avionics Test and Launch Engineer II / Senior
Wallops Island, Virginia, United States
OnsiteFull Time
2+ YOEBachelor in engineering; 2+ years (Level II) or 5+ years (Senior) in engineering design, test, or operations focusing on electrical/software systems; avionics experience; programming; networking knowledge; familiarity with ground/space systems.
Java, Python, HTML, XML, TCP/IP, UDP, Multicast
2w
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Infrastructure Engineering, AVP
Quincy or Boston or Princeton or Clifton or Austin or Kansas City or Berwyn or Kilkenny or Dublin or London or Krakow or Quincy
$90k-$158k/yr HybridFull Time
7+ YOEAVP-level infrastructure engineering role requiring 7+ years Python, full stack development, network automation, SDLC, REST/JSON/XML, and hybrid work model.
Python, Django, REST, JSON, XML, HTML, CSS, JavaScript, React, Bootstrap, Git, CI/CD, Automation, Networking
1mo
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System Test Intern
Edgewood, Maryland, United States
$15-$35/hr OnsiteInternship
0+ YOEUndergrad in process or completed; 0 years experience; familiar with Windows, Linux, virtualization, and Python.
Windows, Linux, Python, Virtualization
1w
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Catastrophe Research Manager
New York or Boston or Philadelphia or Chicago
$105k-$150k/yr OnsiteFull Time
6+ YOE6+ years catastrophe research or model development; PhD or Master’s in Climate Science, Natural Hazards, Applied Statistics; strong RMS background; proficient in R, Python, SQL; excellent communication; experience with model reviews and validation.
R, Python, SQL
1mo
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Electrical Engineer ICCP Energy Management Systems (EMS) Analyst II/III
Philadelphia, Pennsylvania, United States
$38-$45/hr HybridFull Time
Bachelor's degree in Electrical Engineering, Power Engineering, Computer Science, similar engineering degree, or equivalent work experience; strong communication; detail-oriented; team-oriented with ability to learn; process improvement mindset; experience with real-time EMS preferred.
UNIX/Linux, SQL, Python
1w
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CNO Analyst/Programmers
Annapolis Junction or Fort Meade
OnsiteFull Time
CNO Analyst/Programmer with strong C/Python, assembly, Unix/Windows internals, and TS/SCI with poly; multiple experience levels.
Assembly, C, C++, Python, Java, Perl, C#, Makefile, Unix, Windows, Visual Studio, NET, Subversion, Git, Docker, RabbitMQ, JavaScript, Microservice architecture, Backbone, Marionette, Linux
1mo
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Senior Director, Software Engineering
Philadelphia or Alexandria or Ann Arbor
HybridFull Time
10+ YOE5+ Mgmt10+ years in technology leadership with cross-functional teams; 10+ years software engineering; Bachelor's in CS or related field; Proficient in Java and Python.
Java, Python, XML, HTML, XSLT, XML Schema, XQuery, XPath, PDF, TIFF, Angular, Talend, Pentaho, Databricks, Spark, EMR, Hive, Microservices, SOAP, REST, JavaScript, Node.js, AWS, AMQ, JMS, Spring Boot, PostgreSQL, MySQL, SQL Server, Oracle, ETL, SaaS, NL P, ML, AI
3w
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Manager Software Engineering
Fort Washington, Pennsylvania, United States
OnsiteFull Time
10+ YOE5+ MgmtSenior software engineering leader with 10+ years of experience, 5+ in leadership; strong Java/JavaScript/Python; cloud, DevOps, CI/CD; security, architecture, mentorship.
Java, JavaScript, Python, Cloud, DevOps, CI/CD, Docker, Kubernetes, Spring Boot, ORM, Git, Elasticsearch, Logstash, Kibana, Splunk
1w
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Associate Director, Programming (Macros & Automation)
King of Prussia or Waltham or Glattbrugg
$189k-$220k/yr HybridFull Time
10+ YOE10+ years SAS programming, macro development, and automation leadership; knowledge of CDISC; strong collaboration.
SAS, SAS Macro, Python, R
2mo
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AI Researcher Intern DU26
Baltimore, Maryland, United States
$15/hr OnsiteMultiple Commitments Available
0+ YOEPursuing Bachelor's or Master's in CS, Software Engineering, Applied Mathematics, or related field; GPA 3.0+; strong Python/Java/C++/JavaScript experience; familiarity with deep learning tools; able to work >=30 hours/week for 8 weeks.
Python, Java, JavaScript, TypeScript, C++, PyTorch, TensorFlow, Codex, Claude Code, Gemini
1mo
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Research Specialist A (Department of Neurosurgery)
Philadelphia, Pennsylvania, United States
$45k-$50k/yr OnsiteFull Time
1+ YOEBachelor's degree and 0-1 year of experience; scientific programming (MATLAB, Python) preferred; experience with experimental animals preferred.
MATLAB, Python
1w
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Cleared Senior Software Researcher
Annapolis Junction, Maryland, United States
OnsiteFull Time
Active TS/SCI with Full Scope Poly; Bachelor's degree or 4 years relevant experience; proficiency in C, Python, and Assembly; understanding of software vulnerabilities and distributed architectures.
C, Python, Assembly
5d
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Associate Economist
Philadelphia, Pennsylvania, United States
$84k-$138k/yr HybridFull Time
4+ YOEBachelor’s in Economics or related field with 4 years experience, or Master’s with 2 years; experience with data from tax returns, financial statements; econometric analysis; R, Python, SQL.
R, Python, SQL
5d
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Research Assistant in Biomechanics of Locomotion
Philadelphia, Pennsylvania, United States
$41k-$62k/yr OnsiteFull Time
0+ YOEBachelor's in Biomedical Engineering, Biosciences, or related field; MATLAB or Python; strong analytical skills; neuroscience/muscle physiology knowledge helpful; prior research experience required; full-time commitment.
MATLAB, Python
6d
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Human Factors Scientist (Ph.D.)
Philadelphia, Pennsylvania, United States
OnsiteFull Time
Ph.D. in psychology, neuroscience, vision science, or related field; experience in human factors; ability to lead studies; strong communication; programming in Excel, SPSS, MATLAB, Python, or R; Philadelphia area.
Excel, SPSS, MATLAB, Python, R
1mo
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US ETF Strategist
Philadelphia or New York City
HybridFull Time
10+ YOE10+ years in ETF product development or strategy; deep ETF construction and regulatory knowledge; proficiency in SQL, Python, R, Tableau.
SQL, Python, R, Tableau
1mo
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Network-based Anomaly Detection Researcher (5673)
Aberdeen, Maryland, United States
$90k-$120k/yr OnsiteFull Time
PhD in Engineering, Network Science, Neuroscience, CS, Statistics (MS considered); strong research in networks; publications preferred; proficient in Python/SQL/Julia; graph DBs or big data tools; multi-project management; US citizenship with security clearance.
Python, SQL, Julia, Neo4j, TigerGraph, Amazon Neptune, Apache Spark, Scala
1w
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Credit Model Development Quantitative Analyst II - Small Business and Home Secured (Hybrid - see potential locations in job description)
Buffalo or Bridgeport or Wilmington or Baltimore or Washington or New York
$72k-$119k/yr HybridFull Time
1+ YOEBachelor’s degree plus 1 year quantitative modeling experience or 5 years education/work; strong Python; SQL; SAS/R; model development in credit risk.
Python, SQL, SAS, R
11h
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Sr Data Scientist
Baltimore or De Pere or Chicago or Kennett Square or Houston or Warrenville
$131k-$145k/yr HybridFull Time
5+ YOEPython-based data science, ML model development, generative AI, and end-to-end pipelines; Masters/PhD in quantitative field; nuclear/power data domain experience; strong ML/ statistics; proficient in Python/R/Scala/SQL.
Python, R, Scala, SQL, Spark, Hadoop, Databricks, Azure Data Factory
1mo
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Network-based Anomaly Detection Researcher (5673)
Aberdeen, Maryland, United States
$90k-$120k/yr OnsiteFull Time
PhD in Engineering, Network Science, Neuroscience, Computer Science, Statistics, or related field; strong research on complex networks; publications preferred; programming in Python/SQL/Julia; graph databases or big data experience; US citizenship for clearance; ability to manage multiple projects.
Python, SQL, Julia, Neo4j, TigerGraph, Amazon Neptune, Apache Spark, Scala
5d
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Research Support Specialist
Philadelphia, Pennsylvania, United States
OnsiteFull Time
1+ YOEBA/BS in psychology, nutrition, sociology, STEM or related field; 1–2 years lab research experience; strong communication; highly organized; team oriented; Mac OS and MS Office proficient; desirable: basic coding, REDCap, R, Python, neuroimaging/behavioral assessments.
Mac OS, MS Office (Word, Excel, PowerPoint), REDCap, R, Python, neuroimaging, fMRI, MEG
3w
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Bioinformatics Analyst - Auslander Lab
Philadelphia, Pennsylvania, United States
OnsiteFull Time
10+ YOEPhD in Biostatistics, Computational Biology, Bioinformatics, or related field; 10+ years Linux/Unix experience; strong Python and R skills; data visualization and large-scale data processing; experience building bioinformatics tools; strong publication record; domain expertise in cancer biology, microbiome, and computational genomics.
Python, R, Linux, Snakemake, Nextflow, Cloud Computing, High-Performance Computing, Git
2w
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AVP, Quantitative Modeler
Wilmington, Delaware, United States
HybridFull Time
Design and implement mathematical, statistical, and machine learning models; develop analytics; use Python/SAS; build IFRS 9 models; document and validate models.
Python, SAS, Statistical Modeling, Machine Learning
6d
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Quantitative Analytics & Model Consultant Senior - Data Model Analytics
Pittsburgh or Philadelphia or Cleveland or Wilmington or Houston
$80k-$185k/yr OnsiteFull Time
6+ YOE6+ years in quantitative analytics, modeling, or risk management; strong Python and PySpark; experience with large data; CRE experience preferred; model development and documentation skills.
Python, PySpark, Distributed Computing
6d
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Lead, Technology Product Management – AI, Data & Insights
Titusville, New Jersey, United States
$109k-$175k/yr HybridFull Time
3+ YOE2+ Mgmt3+ years in data/insights product development; proven LLM/GenAI deployments; strong Python, cloud, and data engineering skills; leadership of cross-functional teams; excellent communication.
Python, LangChain, SageMaker, AWS, Azure, OpenAI, Cloud, Data Engineering, LLMs
2w
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Lead Analyst, Collections Analytics
Wilmington, Delaware, United States
HybridFull Time
4+ YOEBachelor’s or Master’s in a quantitative field; 4+ years in analytics or software development in financial services; Python and SQL proficiency; Power BI; experience with large datasets and governance; Git familiarity.
Python, SQL, Power BI, Git, Object-Oriented Programming
2mo
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CNO Analyst/Programmer Level 1
Annapolis Junction or Hanover
$135k-$150k/yr OnsiteFull Time
TS/SCI with Polygraph; Bachelor's in CS/IS/Network Engineering or equivalent; IAT Level 2 Certification; multiple experience options for education.
C, C++, Java, Perl, Python, Assembly, Visual Studio, .NET, UNIX, Makefiles
1mo
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DevSecOps Architect – Toolchain Support & Consulting
Little Falls or Santa Clara
$128k-$239k/yr OnsiteFull Time
8+ YOE8+ years in DevSecOps with end-to-end software delivery, CI/CD, SCM, cloud/on-prem, and security tooling.
GitHub, Bitbucket, Azure DevOps, SonarQube, Checkmarx, Veracode, Snyk, Mend.io, Black Duck, GitLeaks, Dependabot, Terraform, Ansible, Docker, Kubernetes, Jenkins, GitHub Actions, Bash, Python, PowerShell, Groovy, YAML
2mo
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Web and Digital Interface Designer (contingent 034)
Huntsville or Aberdeen
HybridFull Time
10+ YOESecret clearance required; 10+ years in web design; BA/BS in CS/Design; strong responsive design, UX, HTML/CSS/JS; DoD cybersecurity and accessibility experience.
HTML5, CSS, JavaScript, Python, PHP, SQL, Adobe Creative Suite, Photoshop, Dreamweaver, PowerPoint, XML, Unix, Windows
1mo
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Lead AI Solutions Architect - Full Stack
Princeton or Glen Allen or Coppell or Waltham or Philadelphia or Riverwoods or New York City or Chicago or Houston
$129k-$226k/yr HybridFull Time
10+ YOELeadership-focused AI solutions architect with 10+ years in full-stack engineering, GenAI/Agentic AI, data science, AI/ML, and applied AI engineering; proven leadership and mentoring experience.
Python, FastAPI, Angular, React, LangChain, LlamaIndex, SQL, NoSQL, Azure, AWS
2d
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2026 Summer Intern - Tech
New York or Austin or King of Prussia
$40/hr HybridInternship
Rising or recent graduates; hybrid in New York City, Austin, or King of Prussia; backend language proficiency; SDLC understanding; Git; strong analytical and communication skills; collaborative mindset.
Python, TypeScript, Git, LangChain, OpenAI APIs, AWS, GCP, Azure, Asana, Jira, Notion, Monday.com, Salesforce, HubSpot
HiringCafe market data
Python Developer Jobs market signals in Middletown, DE, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
770+
Hiring companies
250+
Fresh sample
58% new in 30d
Salary visibility
61% show pay
Companies appearing in this market
Johnson & JohnsonUniversity of PennsylvaniaBarclaysAIGThe Wistar InstituteClarivateLincoln FinancialOneMain Financial
Work location mix in visible results
Hybrid: 30Onsite: 27