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Python Developer Jobs in O'Fallon, IL, US
270+ python developer jobs from 97 companies hiring in O'Fallon, IL, US.
1mo
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Site Reliability Engineer (SRE)
Beavercreek or Huntsville or St. Louis
OnsiteFull Time
1+ YOE1+ years in operations, sys admin, DevOps, or software engineering; BS in CS/CE or related field; TS clearance; systems thinking; observability; basic software engineering; Linux networking; strong communication.
Python, Go, Kubernetes, Argo CD, GitLab, GitHub, Jenkins, Docker, Locust, Gatling, Prometheus, Grafana, Perses
1mo
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Chief Systems Engineer (Onsite)
Arnold or Springfield
$136k-$231k/yr OnsiteFull Time
10+ YOEBachelor's degree with 10 years of relevant experience or Master's with 8 years; Top Secret/SCI clearance; DoD 8570.01/8140.01 compliance; CI/CD/DevSecOps experience; strong leadership and customer-focused communication.
CI/CD, DevSecOps, PostgreSQL, Bash, Red Hat, Cisco, Juniper, Docker, Kubernetes, NFS, Python, Perl, Scripting, Stig/DISA STIG, UNIX, IAVA
2mo
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Sr. Application Security Engineer
San Francisco or Salt Lake City or St. Louis or Boston or Prague or Berlin or Munich or Warsaw or Bratislava or Toronto
$150k-$190k/yr RemoteFull Time
5+ YOE5+ years in application security with container security, Kubernetes RBAC, and Go proficiency.
Go, Kubernetes, CI/CD, Python
3w
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Network Print Systems Engineer
Hazelwood, Missouri, United States
OnsiteFull Time
5+ YOE5+ years network engineering in production printing; 3+ years with digital print devices; experience with print management platforms and RIPs; TCP/IP, DNS, DHCP, VLAN, firewall; PCI/PII security; Bachelor in CS/IT/Engineering or related field.
PaperCut, UniFlow, PrinterLogic, RIPs, SNMP, TCP/IP, DNS, DHCP, VLAN, Firewall, HP, Canon, Xerox, Ricoh, PowerShell, Python
1mo
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Senior Network Engineer -Core/IP Infrastructu
East Peoria or St Peters
$80k-$125k/yr OnsiteFull Time
8+ YOE8–12+ years ISP/telecom network engineering; CCNP/CCIE/JNCIP or equivalent; experience with core IP, routing protocols, and network automation.
Cisco, Nokia, BGP, OSPF, IS-IS, MPLS, CGNAT, DNS, DHCP, IPAM, Python, Ansible, Netconf
4d
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Senior DBA Engineer - Oracle SQL/Cloud
St. Louis or Clayton or Richmond Heights or Maplewood
HybridFull Time
3+ YOE3+ years in production DBA with Oracle or PostgreSQL; on-prem and cloud experience; strong SQL; support for release changes; Bitbucket/Git for scripts; security and performance focus.
Oracle, PostgreSQL, Bitbucket, Git, SQL, RMAN, Data Guard, Terraform, Shell, Python
2mo
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Hybrid Cloud Platform Engineer (PaaS)
St. Louis, Missouri, United States
$155k-$165k/yr HybridFull Time
5+ YOEBachelor's degree in CS or engineering; 5–8 years of platform/derivative engineering; active TS/SCI clearance; DoD 8570 IAT Level II cert.
Red Hat OpenShift, Crossplane, Kyverno, Red Hat GitOps, AWS, Python, Shell, Git, Linux, RHEL, RHCOS, CentOS, GitLab CI, Jenkins, Docker, Kubernetes, CNCF
4d
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AI Red Team Lead Engineer
Minneapolis or Atlanta or Cincinnati or New York or Chicago or Gresham or Charlotte or Irving or Earth City
$133k-$157k/yr HybridFull Time
8+ YOELead AI red team operations; design, execute, and report on AI/ML security testing; mentor engineers; strong cybersecurity and AI knowledge.
Python, PowerShell, Go, C++, Shell
2w
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Ignition and Automation Support Engineer
St. Louis or Clayton
OnsiteFull Time
2+ YOETroubleshoot Ignition-based industrial apps, provide 24/7 support, diagnose and escalate issues, remote diagnostics, HMI/PLC troubleshooting, customer communication.
Ignition, HMI/PLC, Python, SQL, TCP/IP, RDP, VPN, SSH
1mo
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Senior Engineer OT (St. Louis, MO, US, 63101)
St. Louis, Missouri, United States
$105k-$129k/yr HybridFull Time
5+ YOEBachelor's degree in engineering; 5+ years in industrial tech; OT tech, programming skills.
PLC, HMI, DCS, OPC, Python, SQL, C#, Power BI, SSRS, MES, Data Historians
2mo
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Information Protection Advisor
St. Louis or Bloomfield or Philadelphia
OnsiteFull Time
7+ YOE7+ years in application development; Node.js/JavaScript, Python, RESTful APIs, Oracle, MySQL; Linux, shell scripting; architecture discussions; strong problem solving and collaboration.
Node.js, JavaScript, Python, REST, Oracle, MySQL, Linux, Shell scripting, Docker, Jenkins, Okta
2mo
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Senior Solutions Engineer, Majors - Kansas City, MO or St. Louis, MO
Kansas City or St. Louis
OnsiteFull Time
Enterprise solution engineering: security, networking, cloud, and sales support; build relationships with executives; design solutions; proficiency in cloud platforms and scripting; knowledge of security standards.
AWS, GCP, Azure, DNS, TLS, WAF, DDoS, SD-WAN, BGP, HTTP, Python, JavaScript, Golang, Bash
4d
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Senior Technologist
St. Louis, Missouri, United States
OnsiteFull Time
8+ YOEProven Fortran software development with algorithm development; 8+ years in secure computing.
Fortran, Python, AWS, Hadoop, Spark, GDAL, ESRI, OGC standards, Geospatial tooling
2w
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Research Engineering Technician - Engineering
St. Louis, Missouri, United States
$17-$29/hr OnsiteFull Time
Bachelor’s degree in engineering or physics; no specific work experience required; Python-focused software/hardware work; basic lab capabilities.
Python, NumPy, PyQt/PySide6, Pandas, MATLAB/Simulink, C++, Oscilloscopes, Multimeters
2mo
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Post Doctoral Fellow - Das
Saint Louis, Missouri, United States
OnsiteFull Time
Doctoral degree in physical sciences, biochemistry, or computer science required at start (ABD accepted); Linux, Python, HPC, and computational chemistry experience preferred.
Linux, Python, High-Performance Computing, Computational Chemistry
1mo
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Associate Staff Scientist
Hazelwood, Missouri, United States
$92k-$135k/yr HybridFull Time
5+ YOEBachelor's in Life Sciences; 5 years data analysis with Tableau/JMP/RStudio; regulatory/compliance for IVD products; Python/R; strong lab skills.
Tableau, JMP, RStudio, Python, R, Excel
1mo
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IT Internship
Chesterfield, Missouri, United States
OnsiteInternship
Pursuing Bachelor's in CS or related field; interest in automation, development, data analytics; familiar with JavaScript, SQL, REST APIs, Python or PowerShell, HTML/CSS; strong problem solving and communication.
Zoho Creator, Microsoft 365, SQL, REST APIs, Python, PowerShell, JavaScript, HTML/CSS
1d
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Machine Learning Engineers II
Clayton, Missouri, United States
$121k-$161k/yr RemoteFull Time
2+ YOEBachelor’s degree in a STEM field or related and 2+ years of relevant work experience; experience designing, deploying and maintaining ML systems; data modeling; data analysis; programming knowledge; remote work ability; US-based position.
Python, SQL, Machine Learning, TensorFlow, scikit-learn
1w
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Infrastructure Code Development Intern
Madison or Minnetonka or St Louis or Omaha
$16-$21/hr OnsiteInternship
Pursuing Bachelor's or Master's degree; Java/.NET/Python experience; onsite 3 days/week.
Java, .NET, Python
1mo
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Business Process Automation Consultant
Indianapolis or Atlanta or Saint Louis or Louisville or Grand Prairie or Norfolk
HybridFull Time
7+ YOEBA/BS required; 7+ years relevant experience; 3+ years building RPA solutions with .NET or similar languages.
.NET, Python, UiPath, Alteryx, Web development, RPA
5d
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Fire Alarm Video Camera Technical Programmer
Middletown, Connecticut, United States
$25-$35/hr OnsiteFull Time
2+ YOEProgramming and debugging security systems; knowledge of Honeywell, Bosch, Lenel, Milestone; BA/BS preferred; 2 years systems integration experience; strong problem solving and communication.
Java, C++, Python
3d
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Extra Help - Research Associate (EH26-109)
Edwardsville, Illinois, United States
$15/hr OnsiteAll Commitments Available
MS in STEM; proficient with Qualtrics, data analysis tools; AI/ML knowledge; strong cross-team communication.
Qualtrics, data analysis tools, R, Python, SAS, CMS platforms, front-end tools
1mo
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Scientist III / Senior Scientist – Microbial Ecology
Creve Coeur, Missouri, United States
$122k-$168k/yr HybridFull Time
4+ YOEPhD in microbial ecology or related field; 4+ years for Scientist III, 8+ for Senior Scientist; field and lab experiments; microbiome sequencing; data analysis; cross-functional collaboration.
R, Python, Metagenomics, qPCR, Amplicon Sequencing
2w
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FA26-047: Research Faculty Fellow
Edwardsville, Illinois, United States
OnsiteContract, Temporary
3+ YOEMaster’s in Geography or related field; FAA Part 107; experience with USDA CRP data; ecological field surveys; plant species ID from ultra high-res imagery; geospatial/remote sensing tools; AI-enabled workflows.
ArcGIS Pro, ERDAS Imagine, Google Earth Engine, Python
1mo
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Solutions Architect (Tulsa, OK, US, 74101)
Tulsa or Dallas or Houston or Kansas City or Memphis or Oklahoma City or St. Louis
HybridFull Time
7+ YOESenior-level architect with 7+ years in IT solution development; bachelor’s degree in CS/CE/MIS or related field; experience across multiple disciplines and cloud platforms.
AWS, Azure, GCP, Serverless, Containerization, Orchestration, REST, gRPC, GraphQL, Java, C#, Python, Go
2mo
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Sr. Analyst, Advanced Analytics
St. Louis or Saint Louis
OnsiteFull Time
5+ YOEBachelor’s degree in Science, Analytics, Engineering, Math, Economics, or related field; 5–8 years data/analytics experience; 3+ years SQL; 2+ years BI/dashboard development; experience with Databricks/Azure or similar platforms.
SQL, Python, R, Power BI, Databricks, Azure
HiringCafe market data
Python Developer Jobs market signals in O'Fallon, IL, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
270+
Hiring companies
97
Fresh sample
47% new in 30d
Salary visibility
44% show pay
Companies appearing in this market
Washington University in St. LouisRadiance TechnologiesBana SolutionsFiservSaint Louis UniversitySouthern Illinois University EdwardsvilleThe Cigna GroupU.S. Bank
Work location mix in visible results
Onsite: 23Hybrid: 10Remote: 3