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Python Developer Jobs

Calpine

Neurocrine Biosciences

Onsite

Calpine, a business unit of Constellation Energy Corporation (Nasdaq: CEG), is America's largest generator of electricity from natural gas and geothermal resources with operations in competitive power markets. With 79 energy facilities in operation, Calpine’s fleet has the capacity to generate approximately 27,000 MW of electricity – enough to power approximately 27 million homes. Through wholesale power operations and its retail businesses, Calpine serves customers in 22 states and Canada. Its clean, efficient, modern and flexible fleet uses advanced technologies to generate power in a low-carbon and environmentally responsible manner.
The company was established on the premise that a strong commitment to the environment is inextricably linked to excellence in power generation and corporate responsibility. Since its founding in 1984, Calpine has led the power industry in its unwavering commitment to environmental stewardship. In addition, its renewable geothermal plants use steam generated deep below the earth's surface to produce clean, renewable electricity.
Job Summary (includes but is not limited to the following, other duties may be assigned)
The Manager of Application Support will lead a team of 10-15 software developers, including leads, seniors, and juniors, fostering a collaborative, high-performance culture. This role oversees end-to-end solution architecture and development on the Microsoft Azure platform, driving Agile methodologies to deliver scalable, secure, and efficient solutions. The manager will collaborate with cross-functional teams to align technical solutions with business objectives, monitor team performance, and communicate project status, risks, and solutions to stakeholders. The role also involves mentoring developers, managing budgets, and adapting to shifting priorities while maintaining team focus and morale.
Job Responsibilities
<ul>
<li>Lead and mentor a team of 10-15 software developers, promoting a positive, inclusive, and innovative team culture.</li>
<li>Monitor team performance, provide constructive feedback, and support professional development.</li>
<li>Serve as a liaison between business users, application vendors, third-party vendors, and Calpine’s IT and DevOps teams.</li>
<li>Oversee the business unit’s technology platform, including solution architecture, technology evolution, and roadmap development.</li>
<li>Collaborate with cross-functional teams to ensure seamless solution integration and alignment with organizational goals.</li>
<li>Deliver scalable, secure, and efficient solutions using Azure tools such as Fabric, Logic Apps, and Azure Functions.</li>
<li>Leverage expertise in Calpine Energy Solutions’ technology and business processes to address complex business challenges.</li>
<li>Communicate project status, risks, and solutions clearly to stakeholders at all levels.</li>
<li>Identify and drive technical or business improvement initiatives that enhance department performance.</li>
<li>Analyze project estimates, provide cost projections to management, and ensure alignment with budgets.</li>
<li>Differentiate between Capex and non-Capex work for accurate financial reporting.</li>
<li>Manage and adapt to frequent changes in project priorities while maintaining team focus and morale.</li>
</ul>
Job Requirements
<ul>
<li>Bachelor’s degree in Information Systems, Computer Science, or equivalent experience</li>
<li>Minimum of 5 (five) years of experience managing technical teams of 10-15 developers (including leads, seniors, and juniors), with a strong focus on mentoring and performance management. Leadership experience in Agile, cloud-based environments a plus.</li>
<li>Experience aligning technical solutions with business strategies and engaging with senior leadership.</li>
<li>Experience designing scalable, secure, and cost-effective cloud-based architectures.</li>
<li>Extensive experience in Agile methodologies (Scrum or Kanban), including sprint planning, backlog management, and retrospectives</li>
<li>Ability to manage multiple concurrent requests and prioritize workloads effectively.</li>
<li>Strong collaboration skills to work with product managers, DevOps, and business stakeholders.</li>
<li>Skilled in guiding teams through organizational and technical changes with minimal disruption.</li>
<li>Strong analytical skills to resolve complex technical and operational challenges.</li>
<li>Excellent verbal and written communication skills to convey technical concepts to non-technical audiences.</li>
<li>Ability to foster a collaborative, inclusive team environment that encourages innovation and accountability.</li>
<li>Self-motivated, goal-oriented, and capable of independent learning.</li>
<li>Strong decision-making, problem-solving, and initiative-taking abilities.</li>
<li>Knowledge of Calpine Energy Solutions’ CCE business is a plus.</li>
<li>Expertise in Microsoft Azure, including Fabric, Logic Apps, Azure Functions, and related services.</li>
<li>Experience with database technologies like Microsoft SQL and maintaining ETL processes.</li>
<li>Hands-on experience with Azure development tools and proficiency in .NET, Python, or similar frameworks.</li>
<li>Proficiency in Azure DevOps, Jira, or similar tools for workflow and progress tracking.</li>
<li>Knowledge of Azure security best practices, including identity management and compliance.</li>
<li>Experience implementing AI systems is a plus.</li>
<li>Expertise in optimizing Azure-based solutions for performance, cost, and scalability.</li>
<li>Proficiency in monitoring and managing Azure resource costs using tools like Azure Cost Management.</li>
</ul>
Salary Information - Position eligible for annual bonus.
Salary range $105,679 to $155,876
 
Additional Calpine Information
<ul>
<li>Equal Opportunity Employer of Minorities, Females, Protected Veterans, and Individuals with Disabilities.</li>
<li>Calpine is committed to Equal Employment Opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. If you are interested in applying for employment and need special assistance or an accommodation to use our website or to apply for a position, please send an e-mail with your request to <a href="mailto:hrrecruitment@calpine.com" target="_blank" rel="noopener">hrrecruitment@calpine.com</a>. Determination on requests for reasonable accommodation are made on case-by-case basis.</li>
</ul>
Please view Equal Employment Opportunity Posters provided by OFCCP <a href="http://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm" target="_blank" rel="noopener">here</a>

Manager Application Support

Lead and mentor a team of 10-15 developers; manage Azure-based solution architecture; Agile; budgets and stakeholder communication; Bachelor's in IS/CS; 5+ years managing tech teams; Azure, SQL, DevOps.

<h2>Who We Are:</h2>At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. <h2>What We Do:</h2>Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company&#39;s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington&#39;s disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit <a target="_blank" href="https://c212.net/c/link/?t&#61;0&amp;l&#61;en&amp;o&#61;4342843-1&amp;h&#61;4011766363&amp;u&#61;https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4252873-1%26h%3D4039787179%26u%3Dhttps%253A%252F%252Fwww.neurocrine.com%252F%26a%3Dneurocrine.com&amp;a&#61;neurocrine.com">neurocrine.com</a>, and follow the company on <a target="_blank" href="https://c212.net/c/link/?t&#61;0&amp;l&#61;en&amp;o&#61;4342843-1&amp;h&#61;190946743&amp;u&#61;https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4252873-1%26h%3D928986078%26u%3Dhttps%253A%252F%252Fwww.linkedin.com%252Fcompany%252Fneurocrine-biosciences%26a%3DLinkedIn&amp;a&#61;LinkedIn">LinkedIn</a>, <a target="_blank" href="https://c212.net/c/link/?t&#61;0&amp;l&#61;en&amp;o&#61;4342843-1&amp;h&#61;2599080817&amp;u&#61;https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4252873-1%26h%3D3255611529%26u%3Dhttps%253A%252F%252Ftwitter.com%252Fneurocrine%26a%3DX%2B%28formerly%2BTwitter%29&amp;a&#61;X&#43;%28formerly&#43;Twitter%29">X</a> and <a target="_blank" href="https://c212.net/c/link/?t&#61;0&amp;l&#61;en&amp;o&#61;4342843-1&amp;h&#61;3991334160&amp;u&#61;https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4252873-1%26h%3D1536396415%26u%3Dhttps%253A%252F%252Fwww.facebook.com%252FNeurocrine%26a%3DFacebook&amp;a&#61;Facebook">Facebook</a>. (*in collaboration with AbbVie)<h2>About the Role:</h2>Responsible to execute on strategy to scale and accelerate biometrics deliverables by leveraging existing standards and processes to implement automation-centric, AI-enabled workflows that result in regulatory compliant data collection, analysis, and reporting. This role works closely with project leads in Data Management, Statistical Programming and Biostatistics to operationalize existing data and analysis requirements into automation-centric, AI-enabled workflows in a regulatory compliant framework deeply rooted in reusable metadata, lifecycle governance, content reuse and responsible‑AI controls. This role will identify opportunities and partner with leadership to prioritize and design tools that facilitate seamless integration among Data Management, Statistical Programming and Biostatistics to scale and support a growing portfolio and ensure regulatory compliance and inspection readiness._<h2>Your Contributions (include, but are not limited to):</h2><ul><li>Implement and champion continuous improvement of foundational standards that enable automation and consistent execution across studies (e.g., standards rulesets, mappings, reusable templates, workflow checklists, and controlled specifications)</li><li>Drive standards implementation and operationalization aligned to CDISC expectations, including strong a linkage between CDASH-compliant data collection and downstream CDISC-compliant data and subsequent Neurocrine standard analysis/reporting</li><li>Support design and quality of submission-critical outputs, including the Define-XML package, ensuring traceability, consistency and an inspection-readiness mindset</li><li>Build and deploy low/no-code automations that improve: standards adherence and consistency, handoff quality between Data Management, Statistical Programming and Biostatistics, repeatability of analysis and reporting workflows, inspection readiness through controlled outputs and documentation</li><li>Enable governed AI use within Biometrics (creating and implementing use cases, access restrictions, peer review, and automated checks)</li><li>Define inspection-ready evidence for automated/AI-assisted outputs</li><li>Provide training and technical support to end users for effective adoption and utilization of AI and automation solutions</li><li>Shape, with buy-in and endorsement from ADS Leaders, the ADS technology strategy by guiding the adoption of innovative technologies and encouraging a culture of creativity and continuous improvement</li><li>Drive innovation within biometrics by identifying and implementing new tools, technologies, and methodologies to enhance efficiency and effectiveness, while fostering collaboration with peers across relevant functional areas</li><li>Other duties as assigned</li></ul><h2>Requirements:</h2><ul><li>BS/BA degree AND 10&#43; years of relevant biotech/pharma/CRO clinical development experienceORMaster’s degree AND 8&#43; years of related biotech/pharma/CRO clinical development experienceOR</li><li>PhD AND 5&#43; years of related biotech/pharma/CRO clinical development experience</li><li>Considered an expert within the company and may have external presence in area of expertise</li><li>Applies in-depth knowledge of own function, business / commercial / scientific expertise to solve critical issues successfully and innovatively</li><li>Ability to work as part of and lead multiple teams</li><li>Sees broader picture and longer-term impact on division/company</li><li>Excellent leadership, coaching and development skills</li><li>Strong negotiation and influencing skills</li><li>Excellent communication, problem-solving, analytical thinking skills</li><li>Excellent computer skills</li><li>Excellent organizational and time management skills with the ability to work independently and in a team environment to meet established deadlines</li><li>Deep knowledge of CDASH and CDISC industry standards (e.g., SDTM, ADaM, Define.xml) and the increasingly complex regulatory requirements for delivering regulatory quality data</li><li>Experience leveraging standards to create processes that facilitate automation and AI-driven solutions to optimize Analytic and Data Sciences deliverables</li><li>Advanced SAS or R proficiency; &#43;Python and SQL strongly preferred</li><li>Experience with Medidata Rave EDC build and content reuse (CRF standards, edit checks, libraries) and downstream readiness</li><li>Deep knowledge of GxP expectations, data integrity, audit trails, and partnering with IT/Quality on validation</li></ul>#LI-RS1Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description._The annual base salary we reasonably expect to pay is $171,800.00-$235,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

Associate Director Biometrics Standards & Integrations

BS/BA with 10+ years biotech/pharma/clinical development OR MS with 8+ years OR PhD with 5+ years; expert in biometrics standards, CDISC (CDASH/CDISC), automation/AI in analytics; strong leadership and communication.

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