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Python Developer Jobs in Southborough, MA, US

2,100+ python developer jobs from 540+ companies hiring in Southborough, MA, US.

2,165 jobs- Southborough • 50 miles
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Senior Software Engineer
Boston, Massachusetts, United States
$153k-$201k/yr HybridFull Time
Franklin Templeton
Franklin TempletonNYSE: BEN: Global investment firm providing asset and wealth management services.
3+ YOEMaster's degree in Computer Science or related field; minimum 3 years of experience with Java and Python; experience with microservices, cloud native architectures, CI/CD, and security; knowledge of market data APIs and AWS/Snowflake/AngularJS/NodeJS; strong debugging, architecture, and Agile practices.
Java, Python, AWS, Snowflake, SQL, AngularJS, NodeJS, Jenkins, GitLab CI/CD, Harness, Docker, Kubernetes, Okta, Bloomberg, Refinitiv
4w
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Database Developer
Pittsburgh or Boston
HybridFull Time
Confluence
Confluence: Software for investment management data and regulatory reporting.
Expert-level Microsoft SQL Server; advanced SQL/T-SQL; performance optimization; analytics data modeling; investment performance domain knowledge.
Microsoft SQL Server, T-SQL, Python, AI-assisted development tools, SQL performance tuning, Analytics databases
4d
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Senior AI Engineer, AI Solutions
Boston, Massachusetts, United States
$144k-$181k/yr HybridFull Time
CarGurus
CarGurusNASDAQ: CARG: Operates an online marketplace for buying and selling vehicles.
5+ YOE5+ years software engineering; Python; API design; AWS; experience with AI/LLM APIs and production-grade systems; cross-functional collaboration; autonomy.
Python, AWS, LLM APIs, Anthropic/Claude, AWS Bedrock, Salesforce
1w
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Junior Software Engineer (Backend + AI)
Needham, Massachusetts, United States
$90k-$110k/yr HybridFull Time
Newton Research
Newton Research: AI agents for marketing analytics and media planning workflows.
Strong Python skills, web API experience, Git proficiency, database experience, genuine AI/ML interest, and ability to debug AI-generated code.
Python, Django, Django REST Framework, PostgreSQL, Redis, OpenAI API, LangChain, LangGraph, sentence-transformers, vector databases, React, TypeScript, Vite, SCSS Modules, Docker, GitHub Actions, AWS, S3, ECR, MinIO, Sentry, RQ, pytest, Vitest, Playwright
4d
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Robotics Software Engineer - ML and Grasping
Charlestown, Massachusetts, United States
$110k-$135k/yr HybridFull Time
Pickle Robot
Pickle Robot: Automated robotic systems for unloading trucks and containers.
Hands-on ML and robotics software experience; strong Python; cloud knowledge (GCP); BS in Robotics/CS; MS preferred.
Python, GCP, Isaac Sim, MuJoCo
1mo
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Forward Deployed Engineer
Boston or New York or Palo Alto
$70k-$100k/yr HybridFull Time
Workato
Workato: Enterprise platform for automating business workflows and integrating applications.
4+ YOE4+ years in design/development/implementation; 1+ year with Workato or similar orchestration platform; BTech/BE or higher in CS/AI/ML; proven AI engineering experience; strong integration and API knowledge.
Workato, TIBCO, Dell Boomi, MuleSoft, APIs, JSON, Java, Python, Ruby, SOA, ESB, BPM, RPA, Cloud platforms
3w
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AI/ML Research Engineer
Boston or San Francisco
OnsiteFull Time
Manifold Bio
Manifold Bio: Designing tissue-targeted protein therapeutics using AI and in vivo screening.
2+ YOE2+ years with PyTorch/JAX; Python stack; distributed computing; protein/computational biology familiarity; Git; independent problem solving; strong communication.
Python, PyTorch, JAX, NumPy, Pandas, scikit-learn, Git
1mo
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Senior Machine Learning Engineer
Natick, Massachusetts, United States
$115k-$225k/yr HybridFull Time
Cognex
CognexNASDAQ: CGNX: Manufactures machine vision systems and industrial barcode readers.
5+ YOEExperience designing, training, and deploying deep learning models for computer vision; strong Python/C++; knowledge of PyTorch/TensorFlow; embedded systems experience.
Python, C/C++, PyTorch, TensorFlow, Git, CI/CD
1mo
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AI Engineer (Leawood, KS, US, 66211)
Leawood or Burlington
HybridFull Time
Ascend Learning
Ascend Learning: Provides educational software and certifications for healthcare professionals.
3+ YOE3+ years AI or software engineering; BS in CS/AI/Software Eng or related; Azure AI Engineer cert preferred; Python/REST (FastAPI); ML/LLM experience; distributed systems.
Python, FastAPI, Docker, Kubernetes, CI/CD, Azure, Apache Kafka, Angular, React, REST API
3mo
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Senior Software Engineer
Waltham, Massachusetts, United States
$147k-$198k/yr OnsiteFull Time
Markforged
Markforged: Manufactures industrial 3D printers and high-strength materials.
5+ YOE5+ years in software development; BS in Computer Science or equivalent; strong full-stack JS/TS; experience with React/Node; UX prototyping with Figma; AWS/GCP/Azure; PostgreSQL; clear communication.
Node.js, Express, React, Angular, Vue.js, Python, Django, Flask, PostgreSQL, AWS, GCP, Azure, Figma, WebGL, Three.js, D3
1mo
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Senior Full Stack Engineer
Westlake or Jersey City or Merrimack or Smithfield
$97k-$185k/yr HybridFull Time
Fidelity Investments
Fidelity Investments: Provides investment management, retirement planning, and brokerage services.
Experience building web apps in production using Python or JavaScript/TypeScript; strong CI/CD knowledge; version control with Git/Jenkins; collaborative mindset.
Python, JavaScript, TypeScript, Git, Jenkins, CI/CD
2mo
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Quantum Pro Software Engineer
Everett or Santa Clara or Calabasas or Cambridge
$120k-$280k/yr OnsiteFull Time
Keysight Technologies
Keysight TechnologiesNew York Stock Exchange: KEYS: Manufactures hardware and software for electronic test and measurement.
Bachelor’s/Master’s/Ph.D. in CS, EE, or Physics; strong C++/Python; Agile; production-quality software; testing and CI/CD; cross‑functional collaboration.
C++, Python, API development, Unit testing, CI/CD
5d
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Senior Machine Learning Engineer
New York or Boston
$134k-$168k/yr OnsiteFull Time
DraftKings
DraftKingsNASDAQ: DKNG: Provide online sports betting, fantasy sports, and casino gaming.
3+ YOE3+ years of production ML/AI experience; strong ML/stats foundation; Python proficiency; experience with Databricks, Kubernetes, Terraform; excellent communication and leadership.
Databricks, Kubernetes, Terraform, Python
5d
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Software Engineer II, ML Ops
Somerville, Massachusetts, United States
$121k-$157k/yr OnsiteFull Time
Generate Biomedicines
Generate BiomedicinesNasdaq: GENB: Generates novel protein therapeutics using machine learning and generative biology.
2+ YOE2+ years in software or ML engineering; Python proficiency; experience with data pipelines, ETL, relational databases; distributed systems; AWS ECS/Kubernetes; CI/CD and observability.
Python, AWS, Kubernetes, PostgreSQL, Redshift, CI/CD, ETL, Data Pipelines, GPU Clusters, LLM-based tools
2w
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AI/ML Development Senior Engineer
Durham or Lowell or Morgan Hill
OnsiteFull Time
MACOM
MACOMNASDAQ: MTSI: Designs and manufactures semiconductor products for communications infrastructure.
5+ YOEBachelor’s or Master’s in CS/AI/DS; 5-10 years AI/ML engineering; Python and ML frameworks; agentic AI; cloud-based architectures; collaboration across teams.
Python, Pandas, PyTorch, TensorFlow, LangChain, OpenAI, Anthropic, AWS Bedrock, SageMaker, Hugging Face
2w
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AIML Software Engineer, AI for Science
London or Heidelberg or Cambridge or Zug
$136k-$227k/yr HybridFull Time
GSK
GSKLondon Stock Exchange: GSK: Develops and manufactures innovative vaccines and specialty medicines.
Produce scalable AI/ML software and cloud infrastructure; Python; cloud platforms (AWS, GCP, Azure); CI/CD; English fluency.
Python, AWS, GCP, Azure, PyTorch, JAX, TensorFlow, CI/CD, Docker, Kubernetes, Shell scripting
1mo
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Display Engineer 1900H-BFSK
Billerica, Massachusetts, United States
HybridFull Time
E Ink
E InkTaipei Exchange: 8069: Developer and manufacturer of electronic paper display technology.
1+ YOEBS/MS in Electrical Engineering, Physics, or related field; 1-3 years lab research; Python or MATLAB; strong analytical and collaborative skills.
Python, MATLAB, Oscillosopes, Power supplies, Function generators
2mo
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Senior Software Engineer (Applied AI)
Seattle or New York City or Boston or United States
$130k-$200k/yr RemoteFull Time
Pearl Health
Pearl Health: Provider enablement platform for scaling value-based Medicare care models.
5+ YOE5-8+ years in software engineering; hands-on Applied AI/LLM; Python, databases, AWS; RESTful and event-driven architectures; data-intensive applications; mentoring; security practices.
Python, Relational Databases, AWS, REST, Event-driven Architecture, LLMs, RAG, Vector Databases, Embedding Models, Observability, Security (HIPAA, SOC2)
1w
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Machine Learning Engineer - Edge
Dover or Lowell
$86k-$135k/yr HybridFull Time
GN Store Nord
GN Store NordNasdaq Copenhagen: GN: Develops intelligent hearing, audio, and video technology solutions.
2+ YOE2+ years in ML for edge devices; C/C++, Python; TensorFlow Lite or PyTorch; embedded systems; audio/speech processing; model compression; cross‑functional collaboration.
C, C++, Python, TensorFlow Lite, PyTorch, Embedded systems
1w
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Firmware Engineer Co-Op
Andover, Massachusetts, United States
$22-$27/hr OnsiteAll Commitments Available
Schneider Electric
Schneider ElectricEuronext Paris: SU: Global provider of energy management and industrial automation solutions.
Pursuing degree in Computer Science, Electrical Engineering, Electronics or related field; C/C++ and Python; Git; Linux; Agile concepts; embedded systems knowledge; good communication.
C, C++, Python, Git, Linux, Agile, Embedded Systems
1mo
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Software Development Test Engineer II
Needham, Massachusetts, United States
$74k-$124k/yr OnsiteFull Time
SharkNinja
SharkNinjaNYSE: SN: Designs and sells household appliances and beauty technology products
1+ YOEBachelor’s or Master’s in CS/Engineering; 1-2 years embedded software; C/C++, Python, or Java; embedded systems/RTOS; IoT protocols; Git/CI/CD; strong problem solving and communication.
C/C++, Python, Java, Git, CI/CD, MQTT, BLE, Wi-Fi, RTOS, Embedded Systems
1mo
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.NET Full Stack Engineer
Boston, Massachusetts, United States
$155k-$180k/yr HybridFull Time
PA Consulting
PA Consulting: Global consultancy providing innovation, technology, and management strategy services.
8+ YOE8-10 years of experience; .NET full-stack development; ASP.NET Framework/.NET 7; EF Core; relational databases; cloud platforms; YAML-based CI/CD.
ASP.NET, Entity Framework Core, Azure, AWS, GCP, YAML, CI/CD, Azure DevOps, GitHub, Python, PySpark
1mo
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Lead Software Integration Engineer
Boston, Massachusetts, United States
$140k-$180k/yr OnsiteFull Time
Washington Trust
Washington TrustNASDAQ: WASH: Provides personal and commercial banking and wealth management services.
8+ YOE8+ years software engineering; expert Python; strong Azure; REST/SOAP APIs; API security; CI/CD; banking/regulatory experience; independent senior role; strong communication.
Python, Azure Functions, Azure Web Apps, Azure SQL, Entra ID, REST, SOAP, OAuth 2.0, JWT, CI/CD, Infrastructure as Code
2mo
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Structural Engineer, Advanced Analysis
Waltham, Massachusetts, United States
$94k-$120k/yr OnsiteFull Time
Simpson Gumpertz & Heger
Simpson Gumpertz & Heger: National engineering firm specializing in complex structural and building enclosure systems.
5+ YOEMaster’s or Doctorate in Civil/Structural/Mechanical Eng; 5–8 years’ experience; PE license; experience with FEA; programming in Python/MATLAB; travel ability; strong communication.
Abaqus, ANSYS, MATLAB, Python, Mathcad
4w
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Senior Robotics Motion Planning Engineer
Woburn, Massachusetts, United States
OnsiteFull Time
Automated Tire
Automated Tire: Builds robotic systems for automated tire and wheel service.
2+ YOEExpert in motion planning (RRT, RRT*, PRM, CHOMP/STOMP, TrajOpt) with 2+ years MoveIt/MoveIt 2 in production; strong ROS2/C++/Python; experience with collision avoidance, kinematics, and real-time systems.
ROS 2, MoveIt, OMPL, CHOMP, STOMP, Pilz, URDF, SRDF, KDL, TRAC-IK, C++, Python, OctoMap, PCL, Open3D, real-time systems
1mo
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Senior Embedded Software Engineer
Burlington, Massachusetts, United States
OnsiteFull Time
908 Devices
908 DevicesNASDAQ: MASS: Handheld mass spectrometry devices for on-site chemical analysis.
8+ YOESenior embedded software engineer with 8+ years in low-level system development, hardware interfacing, and real-time software.
C, C++, Python, Qt/QML, Yocto, Linux, Windows
2mo
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Full Stack Innovation Engineer
Westborough, Massachusetts, United States
OnsiteFull Time
Cumberland Farms
Cumberland Farms: Operates a chain of convenience stores and gas stations.
5+ YOE5+ years in full-stack development or solutions architecture; experience with AI tools, rapid prototyping, and cross-functional collaboration.
React, Vue.js, Python, Node.js, TensorFlow, PyTorch, Cursor, GitHub Copilot, Figma, AWS, Azure, GCP, MLOps
3w
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Senior Backend Engineer, Enterprise AI
San Mateo or Boston or New York City or Salt Lake City or Lahore
HybridFull Time
Overjet
Overjet: AI platform for dental diagnostics and practice management.
Proven backend development experience; scale enterprise AI product; cloud platforms; mentoring; agile culture; strong communication; AI in workflows.
Go, Python, Java, Google Cloud Platform, Amazon Web Services, Microsoft Azure
2w
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Senior Software Engineer - AI Fintech foundation
Boston or Miami or Austin
RemoteFull Time
Hopper
Hopper: Global travel marketplace and financial technology service provider.
5+ YOE5+ years in production ML or large-scale pricing systems; Python/Scala/SQL; distributed data processing; pricing/forecasting domain experience; strong collaboration and communication.
Python, Scala, SQL
1w
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Associate Software Development Engineer (SDET), IT Software Engineers
Dresher or Baxter or Newton
RemoteFull Time
Ascensus
Ascensus: Administers tax-advantaged retirement and education savings plans.
0+ YOEBachelor’s degree in CS/Engineering or related field; basic programming in C#, Python or Java; desire to learn in Agile environment; knowledge of testing concepts.
C#, Python, Java, PowerShell, Bash
1mo
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Data Engineer II
Atlanta or Boston or Remote US
$75k-$105k/yr HybridFull Time
Crunchtime
Crunchtime: Provides operations management software for the restaurant and hospitality industry.
3+ YOE3+ years in data engineering or software development; SQL + Python; ETL/ELT pipelines; APIs; data quality and testing; cross-functional collaboration.
SQL, Python, APIs, ETL/ELT
2mo
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Senior Machine Learning Engineer (3968)
Manchester, New Hampshire, United States
HybridFull Time
GBG
GBGLondon Stock Exchange: GBG: Provides global identity verification and fraud prevention technology solutions.
Lead development and deployment of ML/CV models in production; mentor engineers; work in an Agile team.
Python, PyTorch, OpenCV, C++, TensorFlow
2mo
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Senior Full-Stack Engineer
Culver City or Linthicum or Allen or Woodcliff Lake or Chicago or Orlando or Baton Rouge or Waltham or Phoenix or Harrisburg or West Valley City or Austin or Alpharetta or San Diego or Indianapolis or Lexington or Parma or Little Rock or Asheville or Birmingham or Chantilly or Washington or Brentwood or Plantation or Fort Collins or San Mateo or Schaumburg or Brooklyn
$140k-$180k/yr OnsiteFull Time
Motorola Solutions
Motorola SolutionsNYSE: MSI: Provides safety and security technology for government and enterprise.
7+ YOE7+ years in software development; Bachelor's degree in CS/Engineering; backend (Node.js) and frontend (React) experience; API integrations; cloud and database experience.
Node.js, HapiJS, Python, JavaScript, React, SQL, Serverless, Lambda, CloudFormation, Elastic Beanstalk, EC2, VPC, DynamoDB, RDS, G Suite, Microsoft Graph, Okta, OneLogin, Slack, Linux, Docker, Datadog, CloudWatch, MQTT, log/data pipelines
6d
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DevOps Engineer
White Plains or Conyers or Roanoke or Independence or Hartford or Savannah or Alexandria or Greensboro or Charleston or Missoula or Charlotte or Huntsville or Hartford or Miami or Tallahassee or Albany or Gainesville or Columbus or Boston or San Antonio or Dallas or Denver or Phoenix or San Francisco or Chicago or Nashville or Portland or Charlotte or Houston or Wilmington or Lexington or Tampa or Baltimore or Raleigh or Las Vegas or Cary or Irvine or Brookfield or Shreveport or Greenville or Van Nuys or Minneapolis or Red Bank or Jacksonville or Seattle or Sarasota or Kennesaw or Palm Beach or Towson or Sacramento or Dayton or Broomfield or Golden or Princeton or Omaha or Oklahoma City or Chesterfield or Schaumburg or Suffolk or Jupiter or Carmel or Canonsburg or Buffalo or Schaumburg or Philadelphia or Schaumburg or Sunrise or St. Louis or Los Angeles or Atlanta or Gulfport or Norwalk or South Portland or Metairie or Virginia Beach or Edina or Richmond or Southfield or Cleveland or Milwaukee or Chattanooga or Fort Worth or Rochester or Grand Forks or Detroit or Jersey City or Boise or Portland or San Ramon or Easley or Duluth or Glenville or Syracuse or West Palm Beach or Cary or Irvine or Brookfield or Shreveport or Greenville or Los Angeles or Atlanta or Orland Park or Columbia or Elmhurst or Portland or San Diego or San Ramon or Myrtle Beach or Gainesville or Hartford or Allentown or Macon or Tampa or Saint Petersburg or Irvine or Raleigh or San Ramon or Lewisville
$77k-$134k/yr RemoteFull Time
Marsh McLennan
Marsh McLennanNYSE: MRSH: Global professional services firm providing risk, strategy, and people solutions.
5+ YOE5+ years software development; cloud (Azure/AWS); CI/CD (Azure DevOps, GitHub Actions); scripting (Python, Bash, PowerShell); Git; strong communication; delivery track record.
Azure, AWS, Terraform, Azure Bicep, Docker, Kubernetes, Git, Azure DevOps, GitHub Actions, Python, Bash, PowerShell
4w
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(Junior – Senior) Software Engineer - Backend/Platform
Somerville, Massachusetts, United States
$90k-$125k/yr HybridFull Time
Laminar
Laminar: Provides AI-powered spectral sensors for industrial manufacturing optimization.
Backend/Platform engineering with strong Python/SQL skills; experience with AWS/Azure; data pipelines; Terraform; NoSQL; security best practices.
Databricks, Terraform, SQL, NoSQL, AWS, Azure, Python, PHP
2w
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Sr. Software Test Engineer
Andover, Massachusetts, United States
$150k-$160k/yr OnsiteFull Time
OSI Systems
OSI SystemsNASDAQ: OSIS: Manufacturer of specialized electronic systems for security and healthcare.
7+ YOEBachelor's in CS or engineering; 7+ years software testing; 5+ years test automation; strong Windows/Linux, on-prem and cloud; Python, shell, REST APIs; Docker helpful; problem-solving; proactive communication; ability to obtain security clearance.
Python, Shell Scripting, REST APIs, Docker, Windows, Linux, Cloud, On-premises
2mo
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Senior Principal AI Engineer -Enfi
Boston, Massachusetts, United States
OnsiteFull Time
Miravoice
Miravoice: AI voice agent platform for automated market research surveys.
12+ YOESenior Principal AI Engineer with 12+ years in software engineering, hands-on production AI/ML, expertise in TypeScript/React/Go/Python, LLMs, AI architectures, and leading technical direction.
TypeScript, React, Go, Python, LLMs, RAG, tooling, AI frameworks
2mo
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Staff Embedded Software Engineer
Waltham, Massachusetts, United States
$150k-$170k/yr OnsiteFull Time
Nova Biomedical
Nova Biomedical: Develops and manufactures advanced medical analyzers and diagnostic systems.
8+ YOEDesign, develop, and optimize embedded firmware; lead firmware architecture; collaborate across teams; 8+ years experience; C/C++/assembly; hardware familiarity; travel <10%.
C/C++, Assembly, Git, Python, Bash, Oscilloscope, Logic Analyzers, Debuggers, SPI, I2C, UART, Microcontrollers, Bare-metal, RTOS
4w
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Staff Software Engineer - Amazon Connect REMOTE
Frisco or Overland Park or Danbury or Franklin or Coral Gables or Tampa or Alpharetta or King of Prussia or Chicago or Boston or Birmingham or New York City or Lake Mary or Charlotte or Houston or Sunrise or Hartford or San Antonio or Alexandria or Independence or Hunt Valley
$116k-$174k/yr RemoteFull Time
The Hartford
The HartfordNYSE: HIG: Provides business and personal insurance, group benefits, and investments.
8+ YOE8+ years in software development and cloud computing; extensive AWS experience; AWS certification required; Bachelor's degree in CS/IT or related field.
AWS, Amazon Connect, AWS Lambda, API Gateway, DynamoDB, EventBridge, CloudWatch, SQS, KMS, S3, Terraform, Node.js, Python, Java
1mo
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Full-Stack Software Engineer
Boston, Massachusetts, United States
$100k-$145k/yr HybridFull Time
Clasp
Clasp: Connects employers and talent through student loan repayment benefits.
2+ YOE2–6+ years of full-stack web development; experience across frontend, backend, and cloud; customer-focused; strong collaboration; comfortable with CI/CD; regulated environments a plus.
JavaScript, TypeScript, React, Next.js, Python, Django, Flask, FastAPI, HTML, CSS, PostgreSQL, AWS, Google Cloud, CI/CD, GitHub Actions, CircleCI, Jenkins

HiringCafe market data

Python Developer Jobs market signals in Southborough, MA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
2,100+
Hiring companies
540+
Fresh sample
57% new in 30d
Salary visibility
70% show pay

Companies appearing in this market

E InkFidelity InvestmentsGSKMACOMPA ConsultingCarGurusConfluenceCumberland Farms

Work location mix in visible results

Hybrid: 40Onsite: 39Remote: 7