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Python Developer Jobs in Southbridge, MA, US

700+ python developer jobs from 200+ companies hiring in Southbridge, MA, US.

701 jobs- Southbridge • 50 miles
1mo
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Postdoctoral Research Associate in Biostatistics - PH 351
Providence, Rhode Island, United States
OnsiteFull Time
Brown University
Brown University: Ivy League university providing undergraduate, graduate, and medical education.
PhD in biostatistics, statistics, computer science, data science, or epidemiology by start date; strong methodological training; experience with R/Python; ability to work interdisciplinary; visa J-1 sponsorship.
R, Python, Git
1w
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AI Research Intern – Ribbon Research Labs (Co-op)
Westford, Massachusetts, United States
OnsiteFull Time, Internship
Ribbon Communications
Ribbon CommunicationsNASDAQ: RBBN: Provides secure IP and optical networking communications software.
MS or PhD student in AI/Data Science/CS; strong Python, PyTorch/TensorFlow; networking knowledge; research end-to-end; Linux; cloud/docker; data wrangling; excellent communication.
Python, PyTorch, TensorFlow, MLflow, Weights & Biases, Docker, Kubernetes, Pandas, Numpy, Scikit-learn
2w
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Engineering Intern - Software AI (Marlborough, US, 01752)
Marlborough, Massachusetts, United States
HybridInternship
Festo
Festo: Festo provides pneumatic and electrical automation technology for industrial production.
Enrolled in a master’s program in Computer Engineering, Software Engineering, Computer Science, AI/ML, or related field; strong Python and AI/ML tooling skills; analytical, problem-solver with collaborative mindset.
Python, LLM APIs, PEFT, NumPy, Pandas, PyTorch, TensorFlow, scikit-learn
2w
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Scientist, Structural Biology
Watertown, Massachusetts, United States
$126k-$140k/yr OnsiteFull Time
Treeline Biosciences
Treeline Biosciences: Develops precision medicines for cancer and serious diseases.
0+ YOEPhD in Structural Biology, Biophysics, Biochemistry, Chemistry, Chemical Biology or related field with 0+ years, or BS/MS with 6+ years in biotech/pharma; crystallography, Linux, Python/shell scripting a plus.
Crystallography tools, Linux, Python, Shell scripting, Mass spectrometry, Biophysical instruments
11h
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Research Scientist (Hartford, CT, US)
Hartford or New York City or San Francisco
$138k-$203k/yr OnsiteFull Time
Munich Re
Munich ReFrankfurt Stock Exchange: MUV2: Global provider of reinsurance, insurance, and risk management solutions.
5+ YOEPhD in Statistics, Computer Science, Data Science or related field; 5+ years data science experience in startups or academia; strong ML, GenAI, uncertainty quantification; Python or similar; English fluency; willingness to travel.
Python
2w
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Scientist II or Senior Scientist, Discovery Proteomics
Watertown, Massachusetts, United States
$90k-$200k/yr OnsiteFull Time
Kymera Therapeutics
Kymera TherapeuticsNASDAQ: KYMR: Develops targeted protein degradation medicines to treat human diseases.
3+ YOEPhD in Biochemistry/Biology/Chemical Biology with 3+ years MS proteomics or 7+ years industry proteomics; expertise in DIA, label-free quant; HPLC/mass spec; data analysis in DIANN/Perseus/R/Python; protomics sample prep and instrument maintenance.
Mass Spectrometry, HPLC, Orbitrap Astral, Orbitrap Exploris 480, DIANN, Perseus, R, Python, nLC-MS/MS
1mo
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Cloud Engineering Manager
Marlborough, Massachusetts, United States
$160k-$190k/yr OnsiteFull Time
TASI Measurement
TASI Measurement: Provides industrial measurement instruments and wireless telemetry monitoring solutions.
7+ YOE2+ MgmtLead architecture and delivery of cloud platform; 7+ years software development, 2+ years managing engineers, AWS, Python, MQTT, IoT, and cloud pipelines.
AWS, Python, MQTT, REST APIs, JIRA, Git
4w
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Statistics Leader / Associate Director of Statistics
Upper Providence or Waltham or Stevenage or London
$150k-$250k/yr OnsiteFull Time
GSK
GSKLondon Stock Exchange: GSK: Develops and manufactures innovative vaccines and specialty medicines.
5+ YOEPhD in Statistics or related field with 5+ years post-degree experience, or MS with 8+ years of clinical development experience; experience with R/Python; oncology statistics leadership.
R, Python, SAS
2mo
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Summer 2026 Cyber Research Intern - Bedford, NH
Bedford, New Hampshire, United States
$25/hr OnsiteInternship, Full Time
Peraton
Peraton: National security and mission-critical government technology services provider.
0+ YOEHS diploma and pursuing BS/BA or MS/PhD in CS/ML/Cybersecurity; proficient in Python (PyTorch/TensorFlow) or C/C++; Linux/Windows; strong communication; ability to develop PoCs and document findings.
Python, PyTorch, TensorFlow, C, C++, Java, Rust, Go, Linux, Windows
2mo
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Senior Director, Advanced Informatics Lead
Tarrytown or Warren or Uxbridge or Armonk
$238k-$397k/yr HybridFull Time
Regeneron
RegeneronNASDAQ: REGN: Developing and commercializing medicines for people with serious diseases.
Proven track record in developing and scaling advanced analytics and AI/ML solutions in healthcare or life sciences; lead data science teams; strong Python/R; data strategy experience; travel up to 20%.
Python, R, Programming languages
3mo
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Data Science Intern - Summer 2026 - Bedford, MA
Bedford, Massachusetts, United States
$40-$50/hr HybridInternship
AspenTech
AspenTech: Provides industrial software for optimizing asset performance and sustainability.
5+ YOEMaster’s in CS/Engineering/OR or related field; 5+ years data analysis and software development; Python, C/C++/C#; ML/AI experience; strong math/statistics; cloud/LLM a plus; US work authorized.
Python, C++, C#, C, Machine Learning, LLM, MLops, Cloud
1mo
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Temporary Laboratory Software Technician
Worcester, Massachusetts, United States
$30/hr HybridPart Time, Temporary
Worcester Polytechnic Institute
Worcester Polytechnic Institute: Private research university focused on science, engineering, and technology.
Proficient in high-level languages; clinical software exp preferred; knowledge of medical data standards; strong debugging and data privacy focus; experience with Git.
C#, Python, C++, Java, Git
1mo
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Associate
Austin or Bridgewater or Charlotte or Hartford or Phoenix or Raleigh or Richardson
$65k/yr OnsiteFull Time
Infosys
InfosysNYSE: INFY: Provides global IT consulting and digital transformation services.
0+ YOEBachelor’s degree in CS/IT or related field; recent graduates; SDLC training; multiple US locations; no visa sponsorship.
Java, Python, C/C++
1mo
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AV Programmer
Andover, Massachusetts, United States
$105k-$130k/yr OnsiteFull Time
Red Thread
Red Thread: Provides integrated furniture and technology solutions for workplaces.
3+ YOEProven AV Programmer with 3+ years experience; bachelor’s preferred; strong programming skills across languages and frameworks.
C#, NET, Python, JavaScript, Lua, C++, Java, SQL, MongoDB, Flask, Django, Git, Bitbucket
3mo
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Software Engineering Intern
Bedford, Massachusetts, United States
$22-$30/hr OnsiteInternship
Werfen
Werfen: Develops and manufactures specialized diagnostic systems for healthcare laboratories.
Pursuing a bachelor’s degree with at least two completed college semesters; interest in engineering or life sciences; ability to multitask.
AWS, Java, Angular, Machine Learning, Python, DevOps, Test Automation
1mo
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Lead AI Solutions Architect - Full Stack
Princeton or Glen Allen or Coppell or Waltham or Philadelphia or Riverwoods or New York City or Chicago or Houston
$129k-$226k/yr HybridFull Time
Wolters Kluwer
Wolters KluwerEuronext Amsterdam: WKL: Provides professional information and software solutions for specialized industries.
10+ YOELeadership-focused AI solutions architect with 10+ years in full-stack engineering, GenAI/Agentic AI, data science, AI/ML, and applied AI engineering; proven leadership and mentoring experience.
Python, FastAPI, Angular, React, LangChain, LlamaIndex, SQL, NoSQL, Azure, AWS
2w
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Sr. Digital Manufacturing Technical Specialist
Norwood, Massachusetts, United States
$100k-$161k/yr HybridFull Time
Moderna
ModernaNasdaq: MRNA: Develops and manufactures messenger RNA medicines and vaccines.
2+ YOEBS/MS in CS/Engineering/Data Science; 2-4 yrs AI/ML in production; strong software engineering; GenAI/LLM; cloud platforms; US work authorization.
Cloud platforms, Generative AI, LLM, APIs, RAG, Python, Software engineering
4d
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Consulting Director - C&M - Mechanical Engineering
Concord, Massachusetts, United States
OnsiteFull Time
PA Consulting
PA Consulting: Global consultancy providing innovation, technology, and management strategy services.
15+ YOE15+ years of mechanical engineering, product development, and consulting leadership; strong business development and client leadership.
SolidWorks, Python, MATLAB, FEA
1w
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Senior Manager, Machine Learning
San Jose or Waltham
$152k-$265k/yr OnsiteFull Time
Adobe
AdobeNASDAQ: ADBE: Provides software for digital media creation and marketing analytics
8+ YOE3+ MgmtEight+ years of software development experience with at least 3 years in management; strong background in generative AI, LLMs, ML model development, and production deployment.
Python, ML Pipelines, MLOps, Cloud Services, Generative AI, LLMs, Claude Code, Cursor AI
1w
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Senior Robotics Verification & Validation (V&V) Engineering Manager
Boston or Raynham
$137k-$236k/yr HybridFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Develops and manufactures pharmaceutical drugs and medical devices.
7+ YOELead a V&V engineering team for robotic medical devices; ensure regulatory compliance and validation across FDA/ISO standards.
DOORS, Jama, Polarion, Python, LabVIEW, MATLAB
2w
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Post Doctoral Research Fellow 
Belmont, Massachusetts, United States
OnsiteFull Time
Mass General Brigham: Provides integrated medical care, research, and clinical training services.
PhD in clinical psychology or related field; experience with psychiatric research; strong data analysis skills.
R, Python, MATLAB, SPSS, SAS
2mo
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Senior Scientist - Oligo Bioinformatics (Billerica, Massachusetts, US, 01821)
Billerica, Massachusetts, United States
$111k-$167k/yr OnsiteFull Time
Merck
MerckFrankfurt Stock Exchange: MRK: Global science and technology in healthcare, life science, and electronics.
3+ YOEPhD in Chemistry, Chemical Engineering, Computer Science or related field with 3+ years in siRNA/ASO/SSO.
Docker, Nextflow, Python, R, MySQL, bioinformatics tools
3w
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Postdoctoral Fellow – AI/ML for Drug Metabolite Identification
Groton, Connecticut, United States
$65k-$108k/yr HybridFull Time
Pfizer
PfizerNYSE: PFE: Develops and manufactures vaccines and medicines for global healthcare
2+ YOEPhD in computational chemistry, cheminformatics, machine learning, data science, or related field; strong ML/AI background; experience with chemical structure data; programming and large-scale data engineering experience.
Python, R, Chemoinformatics, TensorFlow, PyTorch, scikit-learn
5d
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Senior Scientist – Biologics AI Innovation
Waltham, Massachusetts, United States
$117k-$175k/yr OnsiteFull Time
AstraZeneca
AstraZenecaLondon Stock Exchange: AZN: Researches and develops medicines to treat major diseases globally.
2+ YOEMaster's degree with 2+ years or PhD with 0+ years in AI/ML applied to biology, plus strong coding and data skills.
Python, TensorFlow, PyTorch, JAX
1mo
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Postdoctoral Research Associate (Chemistry)
Amherst, Massachusetts, United States
$58k-$62k/yr OnsiteFull Time
Amherst College
Amherst College: Private liberal arts college offering undergraduate degree programs.
0+ YOEPhD in Chemistry or related field; strong independent research, communication, collaboration; experience with wet chemistry and standard analytical techniques; teaching and mentoring; CORI check.
Matlab, Python, R, UV-Vis, Fluorescence, FTIR, NMR, Mass spectrometry
2mo
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Analytical Sciences Associate
Marlborough or United States
$77k-$96k/yr RemoteFull Time
Sumitomo Pharma America
Sumitomo Pharma America: Develops and commercializes therapies for oncology and rare diseases.
0+ YOEBachelor’s or advanced degree in Data Science, Statistics, or Sciences; 0-3 years biotech/pharma experience; strong data analysis and visualization skills; experience with LIMS and statistical tools.
JMP, MATLAB, Minitab, R, Python, LIMS
4d
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Senior Scientist I - Bioinformatics, Biotherapeutics and Genetic Medicine
Worcester, Massachusetts, United States
$97k-$184k/yr HybridFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
8+ YOEBS/MS/PhD in a related field with 0-10+ years of experience; strong biology, bioinformatics, and data analytics skills; proficient in programming and data visualization; experience with CRO data management and lab automation preferred.
SnapGene, Geneious, Genedata Biologics, Pipebio, Benchling, Python, R, SQL, Power BI, Tableau, D3.js, Spotfire, Pandas, NumPy, scikit-learn, Matplotlib, Seaborn, Streamlit
1mo
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Enterprise Data Architect & Integration Lead
Providence, Rhode Island, United States
HybridFull Time
PKF O'Connor Davies
PKF O'Connor Davies: Provides professional accounting, tax, and business advisory services.
10+ YOE5+ Mgmt10+ years in data architecture, software development, or system integration; leadership experience; strong data modeling, API design, and SDLC governance.
Databricks, Snowflake, Microsoft Fabric, REST, GraphQL, SOAP, Webhooks, GitHub, CI/CD, Power Apps, Power Automate, PowerShell, Python, JSON, Node.js, Azure, AWS, Google Cloud
2mo
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Actuary, Annuity Model Development (Radnor, PA, US)
Radnor or Charlotte or Fort Wayne or Greensboro or Hartford or Omaha
$109k-$196k/yr HybridFull Time
Lincoln Financial
Lincoln FinancialNYSE: LNC: Provides life insurance, retirement products, and wealth management services.
7+ YOEActuary with 7-10 years actuarial modeling/valuation, AXIS experience, extensive annuity product knowledge, and strong regulatory/GAAP/Tax understanding; excellent communication; FSA preferred or ASA required.
AXIS, R, Python, SQL, Excel VBA, Tableau

HiringCafe market data

Python Developer Jobs market signals in Southbridge, MA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
700+
Hiring companies
200+
Fresh sample
45% new in 30d
Salary visibility
78% show pay

Companies appearing in this market

Brown UniversityRegeneronAbbVieGSKModernaPfizerTreeline BiosciencesWorcester Polytechnic Institute

Work location mix in visible results

Onsite: 26Hybrid: 13Remote: 1