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Python Developer Jobs in Southbridge, MA, US
700+ python developer jobs from 200+ companies hiring in Southbridge, MA, US.
1mo
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Azure IoT Engineer
Groton, Connecticut, United States
$102k-$154k/yr HybridFull Time
5+ YOEFive years of hands-on Azure IoT experience; degree in a related field; on-site collaboration in industrial environments; strong IoT, edge, security, and data pipelines.
Azure IoT Hub, Azure IoT Edge, Azure Digital Twins, Docker, Python, C#, Node.js, TLS, Certificate-based authentication, Azure Event Hub, Azure Data Explorer, Azure Data Lake, Azure Stream Analytics
1mo
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Senior Systems Engineer
Amherst, Massachusetts, United States
HybridFull Time
7+ YOE7+ years in systems, virtualization, automation; strong scripting; experience with on-prem and hybrid cloud; security/compliance knowledge.
PowerShell, MS Graph, Python, PHP, Bash, VMware, Nutanix, Jenkins, Terraform, Ansible, Git, STIGs, NIST 800-53, NIST 800-171
1mo
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Systems Engineer, Software
Acton, Massachusetts, United States
$106k-$190k/yr OnsiteFull Time
9+ YOEBachelor's degree with extensive engineering experience; 9+ yrs with Bachelor, 7+ with Master, or 4+ with PhD; EO/IR space sensors experience; DoD clearance; strong software and systems integration skills.
C/C++, Python, RTOS, Embedded Systems, Linux, Windows, Networking, Git
1mo
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Staff Applications Engineer
East Greenwich, Rhode Island, United States
OnsiteFull Time
onsemi: Designs and manufactures semiconductor solutions for power and sensing.
5+ YOEBachelor's in Electrical Engineering; 5-7 years in applications engineering for automotive/power ICs; power switching, CAD for schematic/PCB; 48V/EV knowledge; lab equipment; scripting; automotive protocols; MS Office; travel 10%.
Python, LabVIEW, VB, CAD tools
1w
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Azure Data Engineer
West Hartford, Connecticut, United States
RemoteFull Time
8+ YOE8+ years in data engineering/analytics; 5+ years Azure; 3+ years Azure Fabric/lakehouse; ETL/ELT, data modeling, governance, and modern data architectures.
Azure Data Lake Storage, Azure Data Factory, Azure Fabric, Azure SQL Database/Data Warehouse, Logic Apps, Service Bus, Event Grid, Power BI, Purview, Azure DevOps, GitHub, Terraform, Databricks, Python, PySpark, Spark SQL, SQL, ARM templates, Bicep
6d
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Engineer III (Webster, MA, US)
Webster, Massachusetts, United States
$125k-$160k/yr OnsiteFull Time
4+ YOESRE with 4+ years exp (or 6+ with Bachelor's); Linux/Windows; scripting; CI/CD; observability tooling; databases; leadership experience; shift/on-call.
Linux, Windows, Python, PowerShell, JavaScript, Terraform, Ansible, Jenkins, GitHub, Bitbucket, DevOps, Splunk, Dynatrace, YAML, JSON, HTML, XML, MySQL, MongoDB, PostgreSQL
2mo
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Staff Engineer, Digital ASIC Design
Burlington or New York or United States
$175k-$200k/yr HybridFull Time
8+ YOE8+ years in digital IC/ASIC/SoC design; BS/MS/PhD in EE/CE; strong SystemVerilog/Verilog RTL; chip integration; post-silicon support.
SystemVerilog, Verilog, cocotb, Python, RTL, ASIC, SoC
1w
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Software Test Engineer Fall Co-op (Waltham, MA, US)
Waltham, Massachusetts, United States
$45k-$60k/yr HybridInternship
0+ YOEPursuing bachelor’s or graduate degree in Computer Science, Biomedical Engineering, or Physics; graduation Spring 2027–Spring 2028; proficient in Python; able to commit to June 15–December 18; U.S. work eligibility; reliable transportation to Waltham, MA.
Python, C++, MATLAB, Linux, Squish
1mo
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LDLS Test Engineer Intern
Wilmington, Massachusetts, United States
$20/hr OnsiteInternship
Energetiq Technology: Manufactures advanced light sources for semiconductor and scientific applications
0+ YOEPursuing a bachelor's degree in Physics or Systems Engineering; hands-on testing experience; programming experience; able to work cross-functionally and independently.
Python, MATLAB, Test equipment (oscilloscopes, power supplies), Data analysis software
1mo
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Client Engineer III (MedInsight)
Seattle or Appleton or Atlanta or Boise or Wakefield or Chicago or Dallas or Hartford or Omaha or San Francisco or Portland or Portland
$85k-$162k/yr RemoteFull Time
5+ YOE5+ years in analytics/data engineering with client-facing delivery; expert SQL; dimensional modeling; strong software engineering practices; able to lead data-driven implementations.
SQL, Git, CI/CD, ETL, Data Modeling, Python, Cloud
2mo
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Systems Senior Staff Engineer
Littleton, Massachusetts, United States
$124k-$170k/yr OnsiteFull Time
5+ YOEBS/MS in Mechanical or Aerospace Engineering; 5+ years thermal design/validation for high-power electronics; CFD; lab instrumentation; DFX; supplier engagement.
FloEFD, Icepak, MacroFlow, ANSYS Fluent, COMSOL, Python, LabVIEW
1mo
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Sr. Security Systems Engineer
Windsor, Connecticut, United States
$110k-$120k/yr OnsiteFull Time
5+ YOE5+ years in enterprise IT; 3-5 years with Cloudflare WAF; Bachelor's degree or equivalent; experience with security, IAM, LDAP, SSO; scripting; Unix/Windows/VMware.
Cloudflare WAF, SIEM, IAM, LDAP, SAML, OAuth, JWT, REST, SOAP, Unix, Windows, VMware, Bash, Python, JavaScript, Git
2mo
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System Test Engineer – Panel Systems
Natick, Massachusetts, United States
OnsiteFull Time
3+ YOEBachelor's in engineering; strong system-level testing; formal test scripts; IV&V; I/O and control testing; strong documentation; lab environment experience.
Python, LabVIEW
1mo
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R&D Measurement & Automation Engineer
Devens, Massachusetts, United States
$90k-$145k/yr OnsiteFull Time
5+ YOEBachelor's degree in electrical engineering, physics, or related field; 5+ years in integration/test engineering; strong electronics hardware and software experience; willingness to travel and work nights/weekends on occasion.
LabVIEW, Ignition, TwinCAT, Beckhoff PLC, AutoCAD Electrical, AutoCAD, Python, C/C++, Test equipment (oscilloscopes, spectrum analyzers, signal generators), Industrial automation, HMI/GUI development
2w
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Software Design Quality Engineer
Westford, Massachusetts, United States
$61k-$123k/yr OnsiteFull Time
2+ YOE2-5+ years in software design quality/cybersecurity quality; experience with SDLC, Agile, GMP/21 CFR 820, ISO 62304/13485; Jira/Jama; CS, SWE, or related degree.
Jira, Jama, TestComplete, Coverity, Python, C, C#, Java, Visual Studio
2mo
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Dev Ops Engineer III
Westborough or United States
$100k-$140k/yr HybridFull Time
5+ YOEBachelor’s degree or equivalent; 5 years PeopleSoft, Linux, and DevOps; container tech; cloud (AWS/Azure); SQL/NoSQL; network basics; on-call.
PeopleSoft, Oracle Database, Container, AWS, Azure, Kubernetes, Docker, Git, Python, PHP, Perl, Ruby, Java, REST, SSH, NTP, DNS, Docker
2w
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Software Design Quality Engineer
Westford, Massachusetts, United States
$61k-$123k/yr OnsiteFull Time
2+ YOEBachelor's in computer science, biomedical engineering, software engineering or related field; 2-5+ years in software design quality; experience with Agile SDLC; knowledge of GMP/21 CFR 820, ISO 13485/62304; proficiency with Jira/Jama; strong QA and risk management skills.
Jira, Jama, TestComplete, Coverity, C, C#, Java, Python, Scripting Language
2mo
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Splunk & Observability/SIEM Engineer
Canton, Massachusetts, United States
HybridFull Time
Aqueduct Technologies: A forward-thinking technology services firm focused on reliability, security, and operations.
3+ YOEBachelor's in CS/Info Security or related field; 3+ years Splunk admin; strong SPL, Linux; scripting; data normalization; cloud experience; effective communication.
Splunk, Elastic Stack, QRadar, Microsoft Sentinel, Python, Bash, PowerShell, Unix/Linux, AWS, Azure, GCP, SPL, CI/CD
3w
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Tier 3 Support Engineer
Eagle or Nashville or Salt Lake City or Farmington
HybridFull Time
4+ YOE4+ years IT support with Tier 2/3 experience; strong Windows/macOS/Linux, networking, virtualization, cloud, scripting; ITIL and cloud certifications preferred; excellent communication and problem-solving.
Windows, macOS, Linux, VMware, Hyper-V, Azure, AWS, PowerShell, Python, Bash, Active Directory, Azure AD, MFA, Endpoint Management, Patching, Monitoring Tools
2w
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Senior DevOps Cloud Engineer
Norwell, Massachusetts, United States
HybridFull Time
7+ YOE7-8+ years in DevOps/Cloud/Infrastructure; Bachelor’s in CS/Engineering; advanced degree preferred; strong IaC, virtualization, cloud, observability, and leadership skills.
Terraform, CloudFormation, VMware, Docker, Kubernetes, Python, PowerShell, Bash, Go, Datadog, Ansible, Puppet, Chef, Jenkins, GitLab CI, Git, SQL Server, IIS, ELK, Prometheus, Grafana
1w
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Systems Engineer IV (West Greenwich, RI, US, 02817)
West Greenwich, Rhode Island, United States
$44k-$103k/yr OnsiteFull Time
9+ YOESenior systems engineer for architecting and implementing enterprise-scale software and infrastructure; leads design, standards, and mentoring.
Red Hat Linux, Windows Server, OpenShift, VMware ESXi, vSphere, IBM DB2, PostgreSQL, OpenLDAP, Red Hat IDM, Puppet, Ansible, AWS, Azure, Google Cloud, NetApp, Lenovo DM Storage, Ansible Playbooks, Red Hat Satellite, KSH, bash, Python, Java, Ruby
2mo
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Information Protection Advisor
St. Louis or Bloomfield or Philadelphia
OnsiteFull Time
7+ YOE7+ years in application development; Node.js/JavaScript, Python, RESTful APIs, Oracle, MySQL; Linux, shell scripting; architecture discussions; strong problem solving and collaboration.
Node.js, JavaScript, Python, REST, Oracle, MySQL, Linux, Shell scripting, Docker, Jenkins, Okta
20h
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Capgemini Invent / Cambridge Consultants - Engineering Co-op - Embedded Software (Burlington, MA, US)
Burlington, Massachusetts, United States
$20-$35/hr OnsiteInternship
0+ YOEPursuing BS or MS in electrical, computer engineering, computer science, or related fields; some software development experience; C/C++/Rust; MATLAB or Python; good testing and communication skills.
C, C++, Rust, MATLAB, Python
1mo
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Co-Op, Thermal Test Engineer, Fall 2026 (July-December)
Burlington, Massachusetts, United States
$23-$28/hr OnsiteFull Time
0+ YOEPursuing a degree in Mechanical or Industrial Engineering; hands-on aptitude; basics of heat transfer, thermodynamics, and fluid mechanics; lab/test experience; ability to work independently; attention to detail; strong communication.
CAD, Onshape, SOLIDWORKS, Python, MATLAB, DAQ, Sensors, Pumps, Thermocouples, Pressure sensors, Flow meters
3mo
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Security Researcher / Systems Hacker
Lexington, Massachusetts, United States
$140k-$200k/yr OnsiteFull Time
3+ YOEMS or PhD in a related field with extensive systems software research and development experience; strong C/C++, Python, and assembly; security clearance eligibility.
C/C++, Python, Assembly, Rust, LLVM, QEMU, Linux
2mo
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Post Doc - Open Rank
Worcester, Massachusetts, United States
$62k-$76k/yr OnsiteFull Time
PhD in computational biology or related field; method development or sequencing data experience; Unix/Linux and programming (C/C++, Python, Perl, R); strong communication; publications; able to work independently and in teams.
Unix, Linux, C, C++, Python, Perl, R
3d
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AC/RF Hardware Design Engineer, New College Graduate, (Teradyne, North Reading, MA) (North Reading, MA, US)
North Reading, Massachusetts, United States
$69k-$111k/yr OnsiteFull Time
0+ YOEBachelor’s degree in electrical engineering with RF/microwave focus; internships or projects in RF design; proficient with RF tools and programming.
CST, HFSS, Keysight ADS, MATLAB, KiCad, Python, Oscilloscopes, VNAs, Spectrum Analyzers, RF Power Meters
1mo
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Associate Director, MLOps (Staff AI / ML Engineer) - Hybrid
Waltham, Massachusetts, United States
$158k-$180k/yr HybridFull Time
7+ YOESenior ML/AI leader with 7+ years (MS/PhD) or 10+ years (BS) in data science/ML; strong Python, MLOps, and cloud skills; generative AI experience; able to lead cross-functional teams.
Python, Airflow, Prefect, Docker, Github, Github Actions, DataDog, AWS, GCP, LangGraph, Pydantic, FastAPI, Snowflake Cortex, DBT, Spark
2w
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Associate Director, Programming (Macros & Automation)
King of Prussia or Waltham or Glattbrugg
$189k-$220k/yr HybridFull Time
10+ YOE10+ years SAS programming, macro development, and automation leadership; knowledge of CDISC; strong collaboration.
SAS, SAS Macro, Python, R
1mo
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Staff Computational Biologist
Lexington or United States
$166k-$195k/yr HybridFull Time
6+ YOE6+ years in computational biology/data-driven discovery; 1+ year in software/data engineering; Python and R; omics/translational analysis; ETL pipelines; product-owner experience.
Python, R, Omics data analysis, ETL pipelines
4w
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Postdoctoral Associate | Metabolomics and Exposomics | Li Lab
Farmington, Connecticut, United States
$66k-$76k/yr OnsiteFull Time
0+ YOEPhD in bioinformatics, chemistry or biology; Python; publications; strong communication; metabolomics/exposomics a plus.
Python
4w
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AI Integrator #1744026
Chicopee, Massachusetts, United States
$168k-$197k/yr OnsiteFull Time
12+ YOEBachelor's in Engineering/CS; 12+ years software/architecture/data; 5+ years AI/ML; TensorFlow/PyTorch/scikit-learn/Keras; Spark/Databricks/Hadoop; Python/Django; REST/GraphQL; Docker/Kubernetes; DevSecOps; CAC eligibility; US citizenship.
TensorFlow, PyTorch, scikit-learn, Keras, Apache Spark, Databricks, Hadoop, PostgreSQL, Python, Django, Celery, Linux, REST, GraphQL, MQTT, Docker, Kubernetes, CI/CD, DevSecOps
1mo
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Research Intern – Advanced Solution Development
Framingham, Massachusetts, United States
OnsiteInternship
Master’s or PhD candidate in CS or related field; strong AI/ML background; proven research ability; prior software development preferred.
LLM, Python, Machine Learning, Research Frameworks
2mo
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Scientist II, Bioinformatics
Lexington, Massachusetts, United States
$126k-$158k/yr OnsiteFull Time
Cystic Fibrosis Foundation: Funds medical research and provides support for cystic fibrosis.
PhD or Master’s with 5+ years in computational research; experience with NGS, multi-omics, R/Python, ML; strong communication.
R, Python, Shell, Linux, Git
1w
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Associate Director, Biostatistics
Madison or Cambridge Crossing
$190k-$264k/yr OnsiteFull Time
6+ YOEPhD or MS with 6+ or 8+ years in statistics/biostatistics; SAS/R/Python proficiency; regulatory experience; leadership and strong communication.
SAS, R, Python
1mo
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Postdoctoral Research Associate
Storrs, Connecticut, United States
OnsiteFull Time
PhD in statistics, biostatistics, computer science, data science, information science, or related field; strong data science skills; Python or R; effective communication; interdisciplinary collaboration.
Python, R, Machine learning libraries, Statistical software
3mo
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Post- Doctoral Research Associate
Providence, Rhode Island, United States
$58k-$96k/yr HybridFull Time
3+ YOEPhD in computer science, pattern recognition, biomedical engineering, or related field; strong publication record; 3+ years research; grant writing preferred; Python and MATLAB required.
Python, MATLAB, Machine Learning
1mo
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Bioinformatics Scientist/Senior Bioinformatics Scientist
Waltham, Massachusetts, United States
OnsiteFull Time
PhD or MS with 3+ years or BS with 6+ years in bioinformatics/genomics; strong NGS analysis, Python/R, Linux, Cloud, Docker; CRISPR off-target knowledge.
Samtools, BWA, GATK, Picard, BEDTools, Nextflow, Git, GitHub, Linux, Python, R, Docker, AWS, GCP, AWS Batch, Elastic Container Registry, CI/CD, Terraform, AWS CDK
3w
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Economics Specialist (Reston, VA or Walthan, MA HYBRID role)
Reston or Waltham
$61k-$104k/yr HybridFull Time
1+ YOEBachelor in Economics/Public Policy plus 1 year experience or Master’s in Economics/Public Policy; strong analytical, Excel; client-facing communication; Python/Stata/R preferred.
R, Excel, Python, Stata
3w
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Summer-Fall 2026 Co-Op - Process Modelling
Framingham, Massachusetts, United States
$45-$60/hr OnsiteFull Time
Pursuing master's or PhD in Chemical/Biochemical Engineering; willing to relocate to Framingham, MA; authorized to work in the US; programming in Python, MATLAB, or R; experience with mechanistic or hybrid chromatography modeling.
Python, MATLAB, R, GoSilico, Cadet
HiringCafe market data
Python Developer Jobs market signals in Southbridge, MA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
700+
Hiring companies
200+
Fresh sample
40% new in 30d
Salary visibility
77% show pay
Companies appearing in this market
AbbottBrown University HealthCommonwealth Fusion SystemsThe Cigna GroupUMass AmherstBristol Myers SquibbSanofiThe Jackson Laboratory
Work location mix in visible results
Onsite: 33Hybrid: 18Remote: 2