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Python Software Developer Jobs in Milpitas, CA, US

3,500+ python software developer jobs from 820+ companies hiring in Milpitas, CA, US.

3,536 jobs- Milpitas • 50 miles
1mo
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Member of Technical Staff - Compilers
San Francisco, California, United States
$150k-$350k/yr OnsiteFull Time
Gimlet Labs
Gimlet Labs: Optimizing AI inference performance across diverse hardware architectures.
Strong software engineering fundamentals; experience with compiler systems; ability to optimize across hardware boundaries.
C++, Python, LLVM, MLIR, TVM, XLA, GPU lowering
3w
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AI/ML Intern
Arizona or California or Colorado or North Carolina or San Francisco or Utah
$40-$50/hr RemoteInternship
Rocket Lawyer
Rocket Lawyer: Provides online legal document creation and attorney consultation services.
Pursuing BS, MS, or PhD in CS/Math/Stats; basic ML concepts; familiarity with generative AI; interest in LLMs; strong Python.
Python, FastAPI, Flask, Django, TensorFlow, PyTorch
2mo
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Junior Geospatial Data Scientist (Pipeline & Algorithm Focus)
San Francisco, California, United States
OnsiteFull Time
Matter Intelligence
Matter Intelligence: Develops hyperspectral sensors and AI for advanced Earth observation.
BS or MS in a quantitative field; hands-on hyperspectral data experience; strong Python; remote sensing physics knowledge; pipeline and production coding.
Python, GDAL, Rasterio, Xarray, NumPy, SciPy, ENVI, GeoTIFF, NetCDF/HDF
2w
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Ex-Founder
San Francisco, California, United States
OnsiteFull Time
Wispr Flow
Wispr Flow: Provides AI-powered voice dictation software for computers and mobile devices.
Former founder with engineering or growth expertise; for engineers: proficient in TypeScript, React, Python; for growth: scalable growth experience and user-centric mindset.
TypeScript, React, Python
1w
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Member of Technical Staff - AI Product
San Francisco, California, United States
OnsiteFull Time
Eigen: Building an AI-driven social agent as the internet's shared friend.
Experience designing large, maintainable AI systems; autonomous problem solving; strong product sense; experience with Typescript, Python; building agentic systems.
Typescript, Python, Agentic systems
3w
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Member of Technical Staff - Security
San Francisco or New York City
RemoteFull Time
Runlayer
Runlayer: Security and governance platform for enterprise AI agents.
8+ YOE8+ years in security engineering with emphasis on application security and endpoint detection; Python/FastAPI; experience with enterprise security and API/gateway attack patterns.
Python, FastAPI
1w
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Applications Specialist
Cupertino, California, United States
$54-$66/hr OnsiteFull Time
City of Cupertino
City of Cupertino: Provides municipal services and public infrastructure for the community.
2+ YOEFrontend web development, ADA accessibility, database and BI tools, and scripting knowledge.
HTML, CSS, JavaScript, .NET, C#, PHP, Python, XML, SQL, MySQL, Power BI, Tableau, Microsoft Power Platform
3w
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Sr. Generative Design Lead (AEC)
San Mateo, California, United States
RemoteFull Time
Slate Technologies
Slate Technologies: AI-powered project intelligence platform for the construction industry
10+ YOE5+ MgmtSenior-level leadership with 10+ years in computational design, specializing in Grasshopper/Rhino Compute, Python, and C#; experience leading a design technology team in AEC.
Grasshopper, Rhino Compute, Python, C#, Visual Studio Code
4d
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MBA Intern_NexBreak Venture (Product Engineering)
Mountain View, California, United States
$40-$60/hr OnsiteInternship
NewsBreak
NewsBreak: Local news aggregation platform powered by artificial intelligence.
3+ YOEMBA or advanced degree; CS/Engineering background; 3+ years software/ML experience; founder mindset; strong communication; MBA preferred.
Python, Machine Learning, Prototyping, Product Development, Data Analysis
4w
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Intern, AI Engineering
South San Francisco, California, United States
OnsiteFull Time, Internship
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing therapies to treat neurodegenerative and lysosomal storage diseases.
Pursuing Master’s or Ph.D. in CS/AI/ML; strong Python and NLP skills; experienced with LLMs, prompt engineering, RAG; able to collaborate with experts; good communication and documentation.
Python, LLM APIs, Hugging Face, NLP, Git, XML, JSON
2mo
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University 2026 Talent Acquisition AI Product Engineering Intern
Mountain View or McLean or New York City or Tampa
OnsiteFull Time, Internship
ID.me
ID.me: Provides secure online identity verification and digital wallet services.
Pursuing a Bachelor's or Master's in CS/Engineering/AI; strong Python and API skills; experience with automation/AI apps; familiarity with LLM prompting or orchestration; strong systems thinking.
Python, APIs, LLMs, AI frameworks, Workflow automation tools, Webhooks
2w
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Founding Forward Deployed Machine Learning Engineer
San Francisco or Bay Area
HybridFull Time
Adaption
Adaption: Develops efficient AI systems that adapt in real-time.
4+ YOE4+ years industry, 2+ years in customer-facing tech role; strong software engineering; familiarity with ML frameworks; data modeling for training; experience with human feedback/adaptive learning; excellent communication; ownership mindset.
Python, PyTorch, JAX, TensorFlow
1mo
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Member of Technical Staff - Applied ML, RecSys
San Francisco or Boston or Remote
HybridFull Time
Liquid AI
Liquid AI: Develops efficient general-purpose artificial intelligence foundation models.
Hands-on experience building or fine-tuning recommendation models at scale; sequential recommendation architectures; data quality and evaluation design; large-scale data pipelines; Python and PyTorch proficiency.
Python, PyTorch, Large-scale data pipelines, Recommendation models
3mo
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Analog Design Automation Intern
Toronto or Boston or Austin or Santa Clara
$35-$70/hr HybridInternship
Tenstorrent
Tenstorrent: Designs high-performance RISC-V CPUs and AI accelerator hardware.
Co-op or PEY student in Electrical Engineering with analog IC design exposure; Python proficiency; interest in ML concepts; open source tools; strong analytical and communication skills.
Python
4d
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Infrastructure Apprentice
South San Francisco, California, United States
$70k-$80k/yr OnsiteFull Time
Gordian Biotechnology
Gordian Biotechnology: Developing gene therapies using high-throughput in vivo screening platforms.
Apprentice in data infrastructure/software; build pipelines, HPC workflows; collaborate with platform and data teams; full-time, salaried; located in South San Francisco.
Google Cloud, Containerization, HPC, Python, Workflow orchestration, Biotech data analysis
2mo
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Solutions Architect
Boston or San Francisco
HybridFull Time
Physical Superintelligence
Physical Superintelligence: Building AI systems to discover new physics at scale.
Strong systems thinking and coding; production systems; Python/Go/C++; web frameworks; PostgreSQL/Redis; REST/GraphQL; PyTorch/JAX; Kubernetes/Docker; Terraform; HPC/physics interest.
Python, Go, C++, React, TypeScript, Next.js, PostgreSQL, Redis, REST, GraphQL, PyTorch, JAX, Ray, Airflow, Argo, Docker, Kubernetes, Terraform, Prometheus, Grafana
1w
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Forward Deployed Engineering Intern, AI-Native (Hybrid)
Houston or San Francisco
$30-$35/hr HybridFull Time, Internship
Homebase
Homebase: Provides scheduling, payroll, and HR software for hourly teams.
Currently enrolled in a college/university; internship available summer 2026; strong interest in AI-first engineering; experience with Python/JavaScript/TypeScript or React; able to collaborate with non-technical partners.
Python, JavaScript, TypeScript, React
2d
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Embedded SDET CO-Op
San Francisco, California, United States
$35/hr OnsiteFull Time
iRhythm Technologies
iRhythm TechnologiesNASDAQ: IRTC: Provides wearable heart monitors and AI-driven cardiac data analytics.
0+ YOEPursuing a Computer Science/Computer Engineering/Electrical Engineering degree or equivalent; proficient in Python; familiar with OOP; git; test automation; strong debugging and collaboration skills; 6-month duration; SF location.
Python, Git, Test Automation
2mo
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Engineering Lead, Growth and Monetization
New York City or San Francisco
$221k-$295k/yr HybridFull Time
Hex
Hex: A collaborative workspace for data science and analytics.
4+ YOE2+ Mgmt4+ years as full-stack software engineer; 2+ years as technical lead or engineering manager; expertise in frontend (React/TypeScript) and backend; experience with B2B SaaS, experimentation, and billing.
React, TypeScript, Python
6d
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Sr. Net Architect
Berkeley, California, United States
OnsiteFull Time
Matrix Precise
Matrix Precise: Provides artificial intelligence solutions and technology consulting services.
7+ YOELead design/development of .NET 8 ASP.NET Core apps; expert in SQL Server; frontend in React/Angular; healthcare/LIS domain experience preferred.
C#, REST, Microsoft SQL Server, T-SQL, Stored procedures, Query optimization, Indexing strategies, Performance tuning, Database schema design, ASP.NET Core, React, Angular, Git, CI/CD, Python, Sitecore, Tableau, Power BI
1mo
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Member of the Technical Staff — Internal AI Tooling
San Francisco or New York City
$165k-$210k/yr OnsiteFull Time
Stuut
Stuut: Automates business accounts receivable and collections through AI agents.
5+ YOE5+ years full-stack engineering; proficient in Python and TypeScript; experience building data pipelines, APIs, and scalable architectures; skilled with React/Vue/Angular frontend and Django/FastAPI/Flask/Node.js backend; cloud platforms (AWS/GCP/Azure); startup-oriented mindset; strong cross-team collaboration.
Python, TypeScript, React, Vue, Angular, Django, FastAPI, Flask, Node.js, AWS, GCP, Azure, HubSpot, Slack API, n8n, Fathom, Linear, LangChain
2mo
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Member of Technical Staff - Full Stack
San Francisco, California, United States
OnsiteFull Time
Hyperbolic
Hyperbolic: Provides a decentralized cloud platform for GPU computing and inference.
8+ YOE8+ years full-stack experience; expert in TypeScript with Python for backend; experience with Drizzle ORM, Postgres, Vercel; CI/CD via GitHub; strong product sense; excellent communication; proven end-to-end feature shipping; experience with A/B/multivariate testing; large-scale app design and API/frontend architecture.
TypeScript, Python, Drizzle ORM, PostgreSQL, Vercel, GitHub CI/CD, Supabase, Figma, PostHog, OpenAI API, Anthropic API
11h
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Staff Applied AI Researcher - Agentic Reasoning Systems (Brazil)
Dublin, California, United States
OnsiteFull Time
Articul8
Articul8: Builds and deploys secure generative AI platforms for enterprises.
8+ YOE8+ years AI/ML research with production impact; PhD or MSc; strong Python software skills; leadership in research.
Python
1mo
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Full-Stack Builder (AI-Augmented Intelligent Operations Builder)
San Jose, California, United States
HybridFull Time
Trackonomy
Trackonomy: Provides IoT-enabled smart labels for real-time supply chain visibility.
8+ YOE7–10 years of experience across product, design, frontend, backend, IoT, or AI; strong full-stack and AI fluency.
TypeScript, JavaScript, React, Node.js, Python, Go, AWS, Azure, GCP, Time-Series DB, NoSQL, Event Streaming, GitHub Copilot, LLM tools
2w
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AI Conversation Designer
San Francisco, California, United States
RemoteFull Time
JustAnswer
JustAnswer: Connecting people with verified professional experts for immediate help.
2+ YOE2+ years designing, launching, and maintaining chatbot or conversational AI; experience with NLP platforms; experience with LLMs and prompt engineering; coding knowledge; data analysis tools; agile collaboration.
Dialogflow, Watson, Python, HTML, JavaScript, Excel, PowerBI, Asana, Azure Boards, Figma, Lucidchart
2mo
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Member of Technical Staff, Applied AI
San Francisco, California, United States
$150k-$300k/yr OnsiteFull Time
Listen Labs
Listen Labs: AI-powered platform for automated customer interviews and qualitative research.
Strong technical background with AI/ML focus; able to own end-to-end features; effective collaborator.
Python, LLMs, Distributed systems, APIs, SQL, NoSQL
2mo
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Oracle CPQ Architect
Mill Valley, California, United States
HybridFull Time
Pierce Washington
Pierce Washington: Provides quote-to-cash transformation and enterprise software implementation services.
7+ YOEExperienced Oracle CPQ architect with 7+ years in enterprise CPQ/eCommerce, integration, and QA across SDLC.
jQuery, HTML, XML, JavaScript, Python, XSLT, XPath, CSS, HTTP, REST, SOAP, JSON, SQL, React, Vue, Angular
3mo
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Full-Stack Engineering Intern
San Francisco, California, United States
OnsiteInternship
Dryft
Dryft: Automates complex manufacturing decisions using context-aware AI agents.
0+ YOEPursuing or recent graduate; interest in building scalable data-driven agents; backend/infra pro; able to work onsite in San Francisco; strong product sense; shipping production code; comfortable with frontend.
TypeScript, React, Chakra UI, TanStack Router, TanStack Query, Vite, Python, FastAPI, Pydantic v2, SQLModel, Postgres, pgvector, dagster, Langfuse, Pydantic AI
1d
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Platform Lead
San Mateo, California, United States
$235k-$260k/yr HybridFull Time
Stellic
Stellic: Student degree planning and academic advising software platform.
8+ YOE8+ years backend engineering, scalable AI platforms, ElasticSearch-based search, observable systems, strong ownership, async architectures, clear communication, mentoring.
Python, SQL, Django, Angular, React, Remix, PostgreSQL, ElasticSearch, Redis, GitHub, AWS, AWS CodeDeploy, Sentry, Grafana, Prometheus, PostHog, Metabase
8h
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Machine Learning Computer Vision Intern
Redwood City, California, United States
OnsiteTemporary
Syntiant
Syntiant: Provides ultra-low-power AI processors and software for edge devices
Pursuing Bachelor's or Master's in Computer Science/Engineering with hands-on computer vision and PyTorch experience. Industry experience not required but preferred.
PyTorch, C++, YOLO, R-CNN, Transformers, Python, Computer Vision
2mo
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Customer Engineering
Mountain View, California, United States
OnsiteFull Time
Omnissa
Omnissa: Provides AI-powered digital work platforms for secure remote access.
3+ YOE3-5 years in software engineering with focus on customer engineering and support; expert in enterprise software, virtualization, and customer-facing problem solving.
C++, Python, PowerShell, WinDBG, Wireshark, vSphere, AWS, Azure, Active Directory, DNS, Git, Perforce, JIRA, Jenkins
4d
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Solutions Engineer_ HQ
Santa Clara, California, United States
$118k-$130k/yr OnsiteFull Time
Agora
AgoraNASDAQ: API: Provides APIs for real-time voice, video, and conversational AI.
2+ YOECustomer-facing Solutions Engineer with 2+ years in software/solutions roles; strong communication; able to design and guide integrations.
Node.js, Python, JavaScript, React, WebRTC, APIs, SDKs, Real-time communication
1mo
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Director, Core Engineering
Emeryville, California, United States
$243k-$315k/yr HybridFull Time
Pixar Animation Studios
Pixar Animation Studios: Produces computer-animated feature films and animation software.
10+ YOE5+ Mgmt BS or MS in Computer Science; 10+ years engineering experience; 5+ years in engineering leadership; strong software development knowledge; expert in C++ and Python.
C++, Python, USD, Hydra, OpenExec, OpenSubdiv
2mo
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Data Scientist
San Francisco, California, United States
$115k-$155k/yr HybridFull Time
Unison
Unison: Invests in home equity to provide homeowners with cash.
2+ YOEMaster's in quantitative field; 2+ years in data science, quantitative finance, data engineering, or software engineering; strong Python and SQL; experience with distributed data tools (Hadoop, Spark, AWS); proven model development.
Python, SQL, Hadoop, Spark, AWS
2mo
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Senior AI Architect
Dublin, California, United States
$167k-$267k/yr OnsiteFull Time
Cornerstone
Cornerstone: Cloud-based talent management and learning software for organizations.
10+ YOE5+ years AI-powered architecture on AWS; 10+ years software development; strong Python, Java, React; API-first and MLOps experience; AWS services (EC2, S3, RDS, Lambda, EKS, Bedrock, SageMaker); data pipelines and modern AI frameworks.
Python, Java, React, AWS, EC2, S3, RDS, Lambda, EKS, Bedrock, SageMaker, Terraform, CDK, Docker, Kubernetes, REST, GraphQL
2mo
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Computational Biologist
South San Francisco, California, United States
$130k-$170k/yr OnsiteFull Time
NewLimit
NewLimit: Developing medicines that reprogram cells to treat age-related diseases.
Experience with single-cell or multi-omics data analysis; strong software engineering; ML methods for biology; collaboration with experimentalists.
Python, NumPy, SciPy, Pandas, AWS, GCP, Azure, Docker, Singularity, Unix
1d
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Senior Scientist, High Throughput Protein Production and Engineering
Brisbane, California, United States
$141k-$171k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNew York Stock Exchange: BMY: Develops and distributes innovative medicines for serious diseases.
2+ YOEPhD in relevant field with 2+ years OR MS with 5+ years OR BS with 7+ years in pharma R&D; senior-level mammalian expression and protein engineering experience; expertise in high-throughput automation and lab software.
Lynx, PHERAstar, WELLJET, FAST, IDOT, Momentum, Cellario, Python, C#
2w
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Engagement Manager (Tech, Media and Telecom)
San Francisco, California, United States
$220k/yr HybridFull Time
Fractal
FractalNSE: FRACTAL: Provides artificial intelligence and data analytics solutions for enterprises.
10+ YOE10-14 years in analytics consulting or decision science leadership; manage senior client relationships; strong problem-solving; SME in data science, GenAI, product management, software development; excellent communication and leadership.
SQL, Python, Agile, Scrum, Adobe Analytics, Data Analytics Tools

HiringCafe market data

Python Software Developer Jobs market signals in Milpitas, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
3,500+
Hiring companies
820+
Fresh sample
55% new in 30d
Salary visibility
48% show pay

Companies appearing in this market

Articul8Gimlet LabsLiquid AIAdaptionAgoraBristol Myers SquibbCity of CupertinoCornerstone

Work location mix in visible results

Onsite: 25Hybrid: 13Remote: 4

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