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Python Software Developer Jobs in Nazareth, PA, US
210+ python software developer jobs from 88 companies hiring in Nazareth, PA, US.
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Development Lead
Whippany, New Jersey, United States
$132k-$145k/yr HybridFull Time
Experience leading software development, delivering scalable systems, and guiding cross-functional teams in engineering environments.
Java, Spring Boot, Python, OpenShift, AWS, Azure
3w
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Director, AI Engineering and Automation (Remote)
Morristown, New Jersey, United States
$142k-$236k/yr RemoteFull Time
10+ YOE10+ years in software/AI engineering; BS/MS in CS/Engineering; Python; production AI/ML; cloud (AWS); APIs and distributed systems; leadership experience.
Python, AWS, LLM, AI APIs, AI agent frameworks, APIs, Microservices, Distributed systems
1mo
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Consulting Application Engineer
Parsippany or Houston
HybridFull Time
5+ YOEFive+ years in chemical engineering with process simulation software experience; BS in chemical engineering, chemistry, or natural science; fluent English; hybrid role with travel up to 25%.
OLI Studio, OLI Flowsheet: ESP, Aspen HYSYS, Aspen Plus, UniSim, Petro-SIM, VMGSim, HTRI, AVEVA PRO/II, AVEVA DYNSIM, CHEMCAD, gPROMS, PIPESIM, OLGA, SysCAD, METSIM, ProMax, ProTreat, Python
2w
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Staff Engineer I - Govt
New Providence, New Jersey, United States
OnsiteFull Time
DoD security clearance required; US citizenship; degree in Electrical Engineering or related field; strong hardware/software integration; lab-based troubleshooting.
C/C++, Assembly, Python, PLC programming, DAQ systems, embedded systems, SQL
1w
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Lead, Technology Product Management – AI, Data & Insights
Titusville, New Jersey, United States
$109k-$175k/yr HybridFull Time
3+ YOE2+ MgmtBachelor in CS/IT/Data Science; 3+ years data & insights product development; proven LLM/GenAI production; Python/ML; cloud services; lead mid-large data teams; data engineering & science experience.
Python, LangChain, AWS, Azure, SageMaker, Bedrock, OpenAI, Azure ML, LLMs, Data Platforms, Cloud
2w
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Associate Director, Programming (Macros & Automation)
King of Prussia or Waltham or Glattbrugg
$189k-$220k/yr HybridFull Time
10+ YOE10+ years SAS programming, macro development, and automation leadership; knowledge of CDISC; strong collaboration.
SAS, SAS Macro, Python, R
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Technology Lead - US
Pennington, New Jersey, United States
$76k-$99k/yr OnsiteFull Time
4+ YOEBachelor’s degree or foreign equivalent; 4+ years AI/LLM, Python, RAG, embeddings; experience with vector DBs; API-first design; model safety; relocation to Pennington, NJ may be required.
Python, Java, Spring Boot, LLM, Pinecone, FAISS, Embeddings, APIs, Guardrails, PII controls
3w
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Data Integration Programmer
Collegeville, Pennsylvania, United States
OnsiteFull Time
5+ YOEBachelor’s in Computer Science or related field; 5+ years experience; SQL Server; REST/SOAP; HTML/CSS/JavaScript/XML/JSON/JWT; Python/PHP/Node.js for API integration; ERP/Enterprise systems.
Microsoft SQL Server, SQL, REST, SOAP, HTML, CSS, JavaScript, XML, JSON, JWT, Python, PHP, Node.js, ERP, Ellucian Colleague
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Postdoctoral Research Associate - Computational HEP
Princeton or Geneva or Chicago
OnsiteFull Time
PhD in experimental particle physics or related field; strong Python/C++ skills; AI/ML experience; experience with large scientific data analysis; software development for GPUs; collaboration in large teams; strong communication
Python, C++, GPU programming, AI/ML frameworks
2w
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Senior Statistical Programmer, Early Stage Development and Pharmacokinetic/Pharmacodynamic Modeling and Simulation (Hybrid)
North Wales or Rahway
$117k-$184k/yr HybridFull Time
5+ YOESenior SAS programmer with 5 years (BA/BS path) or 3 years (MS path) in clinical trials; strong data handling, analysis, and collaboration.
SAS, SAS/MACRO, SAS/GRAPH, SAS Graphs, SAS Language, CDISC SDTM, CDISC ADaM, R, Python, NonMem
4d
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2026 Summer Intern - Tech
New York or Austin or King of Prussia
$40/hr HybridInternship
Rising or recent graduates; hybrid in New York City, Austin, or King of Prussia; backend language proficiency; SDLC understanding; Git; strong analytical and communication skills; collaborative mindset.
Python, TypeScript, Git, LangChain, OpenAI APIs, AWS, GCP, Azure, Asana, Jira, Notion, Monday.com, Salesforce, HubSpot
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Integration Architect
Reading, Pennsylvania, United States
OnsiteFull Time
Penske Truck Leasing: Provides commercial truck leasing, rental, and vehicle maintenance services.
10+ YOEBachelor's degree; 10+ years in integration design/architecture; REST APIs; Kafka/Flink; API gateways; microservices; containers/k8s; cloud; CI/CD; observability; security; DDD/data mesh.
Kafka, Flink, API gateways, Apigee, Kong, MuleSoft, Microservices, Java, Spring Boot, Go, Python, Node.js, Docker, Kubernetes, AWS, Azure, GCP, CI/CD, GitHub Actions, Jenkins, GitLab, GraphQL, gRPC, WebSockets, Schema registries, OpenTelemetry, ELK, OpenSearch, Prometheus, OAuth2, OIDC, mTLS, DDD, Data Mesh
1mo
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Client Services Consultant
Reston or Promontory or Austin or Plano or Burlington or Princeton or Durham
$107k-$190k/yr OnsiteFull Time
12+ YOEKubernetes SRE with deep systems engineering, customer advocacy, IaC, observability, and strong scripting skills.
Kubernetes, vSphere, Terraform, Helm, GitOps (ArgoCD or Flux), Prometheus, Grafana, Jaeger, OpenTelemetry, Bash, Python
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Manager, Statistical Programming
Parsippany, New Jersey, United States
$103k-$140k/yr OnsiteFull Time
2+ YOEBachelor’s degree or higher in a relevant field; minimum 2+ years SAS programming in clinical research; expert in CDISC SDTM/ADaM; strong communication and collaboration skills.
SAS, R, Python, CDISC SDTM, CDISC ADaM, EDC, Regulatory_submissions
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Lead AI Solutions Architect - Full Stack
Princeton or Glen Allen or Coppell or Waltham or Philadelphia or Riverwoods or New York City or Chicago or Houston
$129k-$226k/yr HybridFull Time
10+ YOELeadership-focused AI solutions architect with 10+ years in full-stack engineering, GenAI/Agentic AI, data science, AI/ML, and applied AI engineering; proven leadership and mentoring experience.
Python, FastAPI, Angular, React, LangChain, LlamaIndex, SQL, NoSQL, Azure, AWS
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Associate
Austin or Bridgewater or Charlotte or Hartford or Phoenix or Raleigh or Richardson
$65k/yr OnsiteFull Time
0+ YOEBachelor’s degree in CS/IT or related field; recent graduates; SDLC training; multiple US locations; no visa sponsorship.
Java, Python, C/C++
2w
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Director, AI and Digital Health
Plymouth Meeting, Pennsylvania, United States
$147k-$184k/yr RemoteFull Time
10+ YOE3+ Mgmt10+ years in software/health tech evaluation and leadership; 3+ years in people management; SaMD, EHR interoperability, cybersecurity, and client-facing testing.
Python, LLMs, AI software, Microsoft Office 365, Windows
2mo
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Research and Development Solution Architect - Digital Lab Operations
Morristown or Cambridge
$134k-$193k/yr OnsiteFull Time
5+ YOE5-8+ years of solution architecture experience; CS/IS/Software Engineering background; strong IT governance, GxP, HIPAA, GDPR knowledge; English communication; vendor management; cross-functional collaboration.
Snowflake, GitHub, IICS, Python, OpenShift, ReactJS, SQL, AWS, Azure
HiringCafe market data
Python Software Developer Jobs market signals in Nazareth, PA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
210+
Hiring companies
88
Fresh sample
43% new in 30d
Salary visibility
70% show pay
Companies appearing in this market
InfosysPrinceton UniversityCrum & ForsterBarclaysBroadcomCSLECRIJohnson & Johnson
Work location mix in visible results
Onsite: 13Hybrid: 7Remote: 3