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Senior Level Python Developer Jobs in Modesto, CA, US
42 senior level python developer jobs from 25 companies hiring in Modesto, CA, US.
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Senior AI Developer
Pleasanton, California, United States
$130k-$163k/yr HybridFull Time
3+ YOE3+ years in software development with 2+ years AI in enterprise; strong Python/Java; hands-on with generative AI platforms, vector databases, RAG; enterprise security and collaboration.
Python, Java, Vertex AI, Anthropic, LangChain, LlamaIndex, Pinecone, Weaviate, Google Cloud
1mo
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Senior Software Test Engineer
Pleasanton, California, United States
$90k-$180k/yr OnsiteFull Time
6+ YOE6+ years in software verification/quality with automation; Python/JS/TS; CI/CD; Docker; test automation frameworks; healthcare/regulatory exposure preferred.
PyTest, Jest, Playwright, REST Assured, Python, JavaScript, TypeScript, GitHub Actions, Azure Pipelines, Docker, Graylog, Datadog
15h
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Full Stack Engineer, Senior
Oakland or Seattle or WA or OH or CA or Long Beach or AZ or CO or CT or FL or GA or MD or MN or NV or OR or El Dorado Hills or Lodi or Rancho Cordova or Redding or San Diego or Woodland Hills or AL or IL or VA or WI or TX or NY
$103k-$174k/yr HybridFull Time
5+ YOE5+ years full stack development; BA/BS or equivalent IT experience; React/Vue/Angular; .NET/Java/Node.js/Python APIs; SQL/NoSQL; Azure preferred; Docker; IaC; CI/CD; AI tools; healthcare experience preferred.
React, Vue, Angular, JavaScript, TypeScript, .NET, Java, Node.js, Python, MS SQL Server, Oracle, NoSQL, REST, Azure, AWS, GCP, Docker, Kubernetes, Ansible, Bicep, ARM, Terraform, GitHub, GitLab, Bitbucket, Git
2w
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Senior Controls Engineer
Livermore, California, United States
$200k-$260k/yr OnsiteFull Time
10+ YOELead design and implementation of control systems for high-energy laser platforms; 10+ years in controls; PLC, embedded and real-time software; C/C++, Python; motion control; system integration.
PLC programming, Embedded systems, Real-time software, C/C++, Python, MATLAB/Simulink
3w
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Machine Learning Engineer III / Senior Machine Learning Engineer - AI Platform
Toronto or Beaverton or Atlanta or Vancouver or Boulder or Pleasanton or Calgary
$156k-$234k/yr HybridFull Time
6+ YOE3+ years ML systems; NLP, IR, recommender; Python, PyTorch/TensorFlow; MLOps, Docker/K8s; PEFT, cloud deployment; 6+ years for senior track; Master’s/PhD preferred.
PyTorch, TensorFlow, Python, Docker, Kubernetes, AWS, GCP, SQL, Spark, PySpark, LangChain, LangGraph, Text-to-SQL, RAG
2w
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Senior Engineer - Field
Pleasanton, California, United States
$130k-$155k/yr OnsiteFull Time
5+ YOE5-8 years field service/product support/system integration experience; bachelor’s in Electrical/Optical/Mechanical engineering; strong hardware/software troubleshooting; willing to travel; must meet U.S. export control requirements for U.S. persons.
Embedded Linux, Python, Bash, Soldering, Fiber Splicing, Electrical Diagnostics
2mo
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Senior Image Quality Engineer
Dublin, California, United States
$140k-$175k/yr HybridFull Time
3+ YOE3-7 years in X-ray/CT imaging or related imaging; degree in Engineering/Physics; strong IQ metrics, processing, and reconstruction know-how; proficient in Python/Matlab; experience with CT concepts and CT-related software.
Python, Matlab, CT imaging, image processing, reconstruction algorithms
1mo
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Senior Reliability Engineer
Los Angeles or El Segundo or San Diego or Riverside or Fresno or San Francisco or Sacramento or Walnut Creek or Fremont or San Jose or Livermore
$109k-$136k/yr OnsiteFull Time
5+ YOEMinimum 5 years of related experience with a Bachelor’s degree; or 3 years with a Master’s; or PhD without experience; or equivalent.
ReliaSoft Weibull++, Ansys Sherlock, Minitab, Python, R, MATLAB
1w
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Senior Data Platform Engineer
Pleasanton, California, United States
$168k-$228k/yr OnsiteFull Time
5+ YOE5+ years in data platform development; cloud-based data pipelines; experience with AWS/GCP/Azure; Python/Java; Snowflake; ETL/ELT; data governance.
Snowflake, Python, Java, Kafka, AWS, Apache Iceberg, Amazon S3, Snowpipes, Streams, Stored Procedures, Airflow
2mo
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Sr. Principal Software Development Engineer
Livermore, California, United States
$136k-$179k/yr OnsiteFull Time
7+ YOESenior software engineer with 7+ years in design, development, and leadership of complex software systems; strong cloud, microservices, containerization, and DevOps experience.
Java, C#, Python, Docker, Kubernetes, AWS, Azure, GCP, CI/CD, Software Architecture, Design Patterns, Data Structures
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Senior Data Engineer
Durham or Pleasanton
$107k-$252k/yr HybridFull Time
5+ YOE7+ years in data engineering; cloud platforms (Azure); Python, Spark, SQL; BI tools (Power BI, Tableau); data governance and quality.
Python, Spark, SQL, Pandas, Power BI, Tableau, Azure, Databricks, Delta Lake, CI/CD, ML Ops, Gen AI
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Senior Field Applications Engineer
Pleasanton, California, United States
$120k-$155k/yr OnsiteFull Time
3+ YOEBachelor’s degree in engineering, 3+ years in lidar or sensing modalities, strong customer engagement, travel up to 20-30%, good communication.
Linux, ROS, C++, Python
1mo
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Senior Software Test Engineer
Pleasanton, California, United States
$90k-$180k/yr OnsiteFull Time
6+ YOE6+ years software verification/quality automation; strong automation framework experience; Python/JavaScript/TypeScript; CI/CD with GitHub Actions and Azure Pipelines; Docker; monitoring tools.
PyTest, Jest, Playwright, REST Assured, Python, JavaScript, TypeScript, GitHub Actions, Azure Pipelines, Docker, Graylog, Datadog
2w
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Senior Engineer, Platform Engineering, AI
Atlanta or New York or Chicago or Pleasanton or Jacksonville
OnsiteFull Time
5+ YOE5+ years infrastructure/DevOps, Kubernetes, Linux, GPU infrastructure; Python/Ansible scripting; vector databases and RAG; agentic AI systems; 24/7 operations; English proficient.
Kubernetes, Linux, Python, Ansible, GitOps, CUDA, NVIDIA drivers, NVIDIA AI Enterprise, GPUs, vector databases, embedding infrastructure, RAG pipelines, MCP, agent memory systems, semantic search, workflow/orchestrion automation tools, Run:AI, NCCL, cuDNN
2mo
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Embedded Flight Software Test Engineer Staff
Littleton or Pleasanton or Sunnyvale
$114k-$201k/yr OnsiteFull Time
Embedded software test development, MBSE, Python, Agile (Jira), IBM DOORS/Cameo, Git, TS/SCI clearance.
Cameo System Modeler, Python, Jira, IBM DOORS, Git/GitLab
1w
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IT Applications Engineer V - Data Science, Data & AI Engineering, Application Engineering
Pleasanton, California, United States
OnsiteFull Time
5+ YOESenior IT engineer with 5+ years in data science/AI, leadership, CS-related degree, proficient in Python/Java/SQL, cloud/CI/CD, GenAI–Healthcare focus.
Python, Java, TypeScript/JavaScript, SQL, Databricks, Spark, Delta Lake, GitHub Actions, Azure DevOps, Jenkins, MLflow, LangChain, LangGraph, MONAI, MedGemma
2mo
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Senior SAP HANA Cloud Data Platform Engineer
Morgan Hill, California, United States
$150k-$200k/yr OnsiteFull Time
8+ YOE8+ years SAP HANA development, SAP BTP HANA Cloud, data modeling, and analytics experience; strong SQLScript, Python, and Git skills; on-site in Morgan Hill, CA.
SAP HANA, SAP BTP HANA Cloud, SQLScript, SAP Analytics Cloud, Git, Python
1w
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Senior Biospecimen Specialist
Pleasanton, California, United States
$80k-$148k/yr OnsiteFull Time
3+ YOEBachelor's degree in a scientific discipline; 3 years in molecular biology or clinical studies; biospecimen management/clinical data management experience; cross-functional collaboration; SQL/Python/R preferred.
SQL, Python, R
2mo
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Senior AI Architect
Dublin, California, United States
$167k-$267k/yr OnsiteFull Time
10+ YOE5+ years AI-powered architecture on AWS; 10+ years software development; strong Python, Java, React; API-first and MLOps experience; AWS services (EC2, S3, RDS, Lambda, EKS, Bedrock, SageMaker); data pipelines and modern AI frameworks.
Python, Java, React, AWS, EC2, S3, RDS, Lambda, EKS, Bedrock, SageMaker, Terraform, CDK, Docker, Kubernetes, REST, GraphQL
2mo
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Kubernetes Engineer
Livermore, California, United States
$146k-$223k/yr HybridFull Time, Temporary
Mid-Senior level Kubernetes engineer with DOE Q clearance eligibility; strong container and cloud-native experience; on-prem automation and cluster orchestration; security and observability focus.
Kubernetes, Ansible, Puppet, CI/CD, RBAC, OIDC, Prometheus, Grafana, Linux, Python, Bash, Puppet, Kubeadm, Etcd
1w
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Communications DSP Engineer
Livermore, California, United States
$185k-$215k/yr OnsiteFull Time
DSP expert for high-speed coherent systems; MS or PhD in EE/CE; active clearance or eligibility; strong DSP, system modeling, and algorithm development skills.
MATLAB, Python, C++, C
2w
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Process Engineer Lead - GUS (PATTERSON, CA, US, 95363-8871)
Patterson, California, United States
$95k-$158k/yr HybridFull Time
5+ YOEBachelor’s in related field; 5+ years process engineering; Lean/Six Sigma; CAD/Visio/Smartsheet; SQL/Python/Java/Scala; strong PM and mentoring skills.
CAD, Visio, Smartsheet, MS Office, SQL, Python, Java, Scala
19h
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Senior Applied AI Researcher (Dublin, CA)
Dublin, California, United States
OnsiteFull Time
5+ YOEPhD or MSc in CS/ML; 5+ years AI/ML research; 2+ years building LLM-based systems; distributed training; production-grade Python.
Python, DeepSpeed, FSDP, Megatron-LM, Kubernetes
1mo
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Staff Software Engineer - Data Platform
Pleasanton, California, United States
OnsiteFull Time
Design scalable data ingestion pipelines; build platform tooling; cloud infra; distributed systems; data pipelines with Kafka/Kinesis; databases and search (SQL, Elasticsearch, MongoDB); monitoring (Prometheus, Grafana, Datadog); containers (Docker, Kubernetes).
Python, Golang, NodeJS, AWS, GCP, Azure, Redshift, BigQuery, Apache Kafka, AWS Kinesis, Elasticsearch, MongoDB, Presto, Snowflake, Prometheus, Grafana, Datadog, Docker, Kubernetes
3w
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Principal SoC DFT Engineer, HBM
Richardson or Folsom
$162k-$344k/yr OnsiteFull Time
7+ YOE7+ years in SoC design, DFT, or implementation for complex digital ASICs/SoCs; BS/MS in EE or CE; strong DFT and RTL-to-GDS experience.
Siemens, Synopsys, Cadence, Python, Tcl, Perl
1mo
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Principal Bioinformatics Scientist
Pleasanton, California, United States
$139k-$259k/yr OnsiteFull Time
6+ YOEPhD or Master's in Bioinformatics/Computational Biology/Statistics; 6+ years in clinical diagnostics; expertise in DNA/RNA sequencing data analysis; proficient in R/Python; Linux; visualization; NGS lab workflows; Snakemake/Nextflow; cancer biology; independent informatics development.
R, Python, Snakemake, Nextflow, Linux
1mo
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Forward Deployed AI Engineers
Pleasanton, California, United States
$130k-$180k/yr HybridFull Time
Experience building AI/ML in production; strong ML, optimization, and system design; proficient in Python, Java, C++, TypeScript/JavaScript; able to deploy across complex systems; US security clearance preferred; Master’s or Bachelor’s degree.
Python, Java, C++, TypeScript/JavaScript
HiringCafe market data
Senior Level Python Developer Jobs market signals in Modesto, CA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
42
Hiring companies
25
Fresh sample
50% new in 30d
Salary visibility
88% show pay
Companies appearing in this market
AbbottFormFactorLawrence Livermore National LaboratoryRocheVector AtomicWorkdayArticul8Cornerstone
Work location mix in visible results
Onsite: 30Hybrid: 12