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Senior Python Developer Jobs in Keystone, CO, US
150+ senior python developer jobs from 51 companies hiring in Keystone, CO, US.
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Sr Staff / Senior Python Software Engineer
Boulder, Colorado, United States
$126k-$175k/yr OnsiteFull Time
6+ YOEBachelor’s degree in CS/Engineering/Math/Physical Sciences; 6+ years of professional Python software engineering; microservices and distributed systems; real-time data processing pipelines; automated testing; Linux; Git; DoD clearance; strong communication.
Python, Linux, Docker, Git, pytest, CI/CD, Microservices, Distributed Systems, REST APIs, protobuf, ZeroMQ, Kafka, gRPC
3w
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Senior Software Developer
Louisville, Colorado, United States
$118k-$144k/yr OnsiteFull Time
5+ YOE5+ years of professional software development; strong SQL; Python; Git; REST APIs; pytest or similar testing; CI/CD experience; ability to own features end-to-end.
Python, SQL, Git, REST APIs, pytest, JavaScript, TypeScript, Node.js, CI/CD, GitLab CI
1w
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Senior Software Engineer
Boulder, Colorado, United States
$145k-$175k/yr OnsiteFull Time
Foresight Diagnostics: Develops ultra-sensitive blood tests for cancer recurrence monitoring.
8+ YOE8+ years full-stack development; Python backend; React frontend; PostgreSQL; Docker/Kubernetes; AWS or GCP; strong problem-solving and communication.
Python, React, PostgreSQL, Docker, Kubernetes, AWS, GCP
1mo
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Senior Firmware Engineer
Boulder, Colorado, United States
$150k-$200k/yr OnsiteFull Time
Embedded firmware development for ARM-based MCUs; C, Python; drivers (SPI, RS-232, CAN, Modbus); debugging and problem solving; degree in EE/CS or equivalent experience.
STM32 ARM MCU, SPI, RS-232, CAN, Modbus, JTAG, ARM assembly, Python, C, Linux, TensorFlow, CUDA
2mo
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Senior Spacecraft Software Engineer
Boulder or Glasgow
$131k-$171k/yr HybridFull Time
Spire Global: Operates a satellite constellation providing data and global analytics.
Proficient in C++ or Python; FPGA development; DSP; GNSS signal processing; cloud-based systems; strong software engineering skills.
C++, Python, FPGA, VHDL, HLS, DSP, GNSS, AWS
1w
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Engineer Senior – Embedded Software
Boulder, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS degree or higher; 4+ years’ related experience; active Top Secret/SCI clearance; Rust, C/C++, Python, Embedded Linux; FPGA interaction; MQTT/ZeroMQ; Yocto/PetaLinux; software design, development and testing.
Rust, C/C++, Python, Embedded Linux, Yocto, PetaLinux, MQTT, ZeroMQ, UML
5h
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Full Stack Engineer, Senior
Oakland or Seattle or WA or OH or CA or Long Beach or AZ or CO or CT or FL or GA or MD or MN or NV or OR or El Dorado Hills or Lodi or Rancho Cordova or Redding or San Diego or Woodland Hills or AL or IL or VA or WI or TX or NY
$103k-$174k/yr HybridFull Time
5+ YOE5+ years full stack development; BA/BS or equivalent IT experience; React/Vue/Angular; .NET/Java/Node.js/Python APIs; SQL/NoSQL; Azure preferred; Docker; IaC; CI/CD; AI tools; healthcare experience preferred.
React, Vue, Angular, JavaScript, TypeScript, .NET, Java, Node.js, Python, MS SQL Server, Oracle, NoSQL, REST, Azure, AWS, GCP, Docker, Kubernetes, Ansible, Bicep, ARM, Terraform, GitHub, GitLab, Bitbucket, Git
1mo
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Senior Engineer - Advanced Test Software
Westminster, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS in Engineering or related field; 4+ years experience; Python and Ruby; hardware interfacing; CI/CD; containerization; willingness to obtain Top Secret/SCI clearance.
Python, Ruby, Docker, Podman, CI/CD, Linux, Windows, BASH, PowerShell, Git, Veristand, LabVIEW
1w
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Senior AI/ML Engineer
New York or Santa Monica or Los Angeles or Palo Alto or Chicago or Washington D.C. or Boston or Colorado or Seattle or San Francisco or San Diego or Reston
OnsiteFull Time
5+ YOE5+ years in AI/ML; hands-on with Azure/AWS; Python; LLMs; data integration; LangChain or similar; cloud security and governance.
Python, Azure, AWS, LangChain, LangSmith, Pydantic AI, APIs, Data Ingestion, Data Lakes, Data Warehouses
3w
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Machine Learning Engineer III / Senior Machine Learning Engineer - AI Platform
Toronto or Beaverton or Atlanta or Vancouver or Boulder or Pleasanton or Calgary
$156k-$234k/yr HybridFull Time
6+ YOE3+ years ML systems; NLP, IR, recommender; Python, PyTorch/TensorFlow; MLOps, Docker/K8s; PEFT, cloud deployment; 6+ years for senior track; Master’s/PhD preferred.
PyTorch, TensorFlow, Python, Docker, Kubernetes, AWS, GCP, SQL, Spark, PySpark, LangChain, LangGraph, Text-to-SQL, RAG
1mo
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Senior Embedded Software Engineer
Louisville, Colorado, United States
$140k-$175k/yr HybridFull Time
5+ YOEBachelor's or master's in electrical/embedded systems; 5+ years hardware validation; proficient in C/C++/Rust; Python; Linux; test equipment; Git.
C/C++, Rust, Python, Linux, Git, Oscilloscope, DMM, OSA, VNA, UART, SPI, I2C, USB
5d
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Senior Software Engineer, Level 3 - Embedded - Clearance Required
Littleton, Colorado, United States
$93k-$164k/yr OnsiteFull Time
Embedded software development experience; C/C++, Python; Linux; Agile; Top Secret/TS clearance required; ability to lead in a collaborative, multi-disciplinary team.
C/C++, Python, Linux, Agile
1mo
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Senior Engineer I - Systems
Boulder, Colorado, United States
$70k-$143k/yr OnsiteFull Time
5+ YOEBachelor's in STEM; 5+ years in systems engineering; Python/MATLAB experience; strong communication; US citizenship.
Python, MATLAB, Oscilloscope, Spectrum Analyzer, Multimeter
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Senior Edge AI Perception Engineer
Arvada, Colorado, United States
$150k-$250k/yr OnsiteFull Time
Direct real-world experience in computer vision, deep learning, or edge AI; proficient with CUDA, TensorRT, NVIDIA DeepStream, TAO Toolkit, PyTorch/TensorFlow; experience deploying AI pipelines on embedded edge platforms (Jetson Orin/Thor); knowledge of object detection, semantic segmentation, and depth estimation; strong C++ and Python.
CUDA, TensorRT, NVIDIA DeepStream, TAO Toolkit, PyTorch, TensorFlow
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Senior DevOps Engineer - Lunar Permanence
Denver or Littleton
$182k-$254k/yr OnsiteFull Time
Blue Origin: Develops reusable rockets and systems for human spaceflight.
8+ YOE8+ years experience; Linux, Docker, CI/CD, AWS (VPC, EC2, EKS); IaC (Terraform/CloudFormation); Python; GitLab; Kubernetes; containerization; monitoring; security compliance.
Linux, Docker, Kubernetes, Terraform, CloudFormation, AWS, GitLab, Python, CI/CD
3mo
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Senior Staff Software Engineer — Application Engineering
Bothell or Boulder or College Park
$193k-$253k/yr HybridFull Time
12+ YOE12+ yrs backend/full-stack; 5+ yrs CI/CD; 5+ yrs C/C++ or Rust; 3+ yrs Docker/Kubernetes; shipping containerized apps; quantum computing background; using coding tools daily.
Python, Golang, GitHub Actions, Jenkins, C/C++, Rust, Docker, Kubernetes, CUDA, OpenMP, Airflow, Dagster, Temporal
1mo
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Senior ML Software Engineer, Watch Software
Denver or Boulder or Cupertino or San Diego
HybridFull Time
M.S. or Ph.D. in ML/CS; strong Python; on-device ML; PyTorch/TensorFlow; Swift/Objective-C; excellent communication.
PyTorch, TensorFlow, Python, Swift, Objective-C
1mo
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Senior Environmental Test Engineer
Golden or San Francisco or Toulouse
$150k-$200k/yr OnsiteFull Time
7+ YOEBachelor’s degree in Electrical, Mechanical, Aerospace, or Systems Engineering; 7–10 years aerospace hardware testing; familiarity with environmental test standards; data acquisition; scripting (Python, MATLAB, LabVIEW); hands-on test lab experience; strong problem-solving and ownership.
Python, MATLAB, LabVIEW, Data Acquisition, Instrumentation, Control Systems
2mo
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Senior Flight Dynamics Engineer
Boulder, Colorado, United States
$150k-$200k/yr OnsiteFull Time
7+ YOESenior flight dynamics engineer with 7+ years in spacecraft flight dynamics or mission design; strong Python/C++ tooling; experience with orbit propagation, maneuver targeting, covariance analysis; able to support spacecraft operations.
Python, C++, GMAT, STK, Orekit, MONTE
4d
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Senior Hardware Engineer
Boulder, Colorado, United States
$140k-$160k/yr OnsiteFull Time
Atom Computing: Building scalable quantum computers using arrays of neutral atoms.
5+ YOESenior hardware engineer with 5+ years in board-level analog/digital circuit design, Altium, and hardware testing.
Altium Designer, Oscilloscope, Spectrum Analyzer, Logic Analyzer, Signal Generator, Python
1w
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Engineer Senior - Systems - Mission Performance
Boulder, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS in Engineering or related field; 4+ years experience; TS/SCI clearance; Python; signal processing; able to document results and present findings; strong teamwork.
Python, Model Based Systems Engineering, STK, AFSIM, PDS/processors
3w
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Lead Sr Staff Software Engineer - Front End Fundamentals
Bellevue or Boulder or Chicago or Denver or Irvine or Los Angeles or New York or San Francisco or San Jose or Seattle or Ventura
$166k-$305k/yr HybridFull Time
13+ YOE1+ MgmtSenior frontend leadership role requiring 13+ years of software development, 1+ year of people management, strong TypeScript/JavaScript or other languages, cloud and distributed systems experience, and mentoring.
TypeScript, JavaScript, C#, Java, C, C++, Python, SQL, Scala
3w
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Staff Software Engineer
Westminster, Colorado, United States
$102k-$170k/yr HybridFull Time
5+ YOEUS citizen; BS degree in CS or Engineering or equivalent experience; 5+ years in complex software development; Python web services; Linux; REST/JSON/YAML; test automation experience.
Python, Django, Linux, REST/JSON/YAML, Cucumber, Gherkin, Behave, Kubernetes, Docker, Jenkins, Helm, Terraform, RabbitMQ, PostgreSQL, Redis, Elasticsearch, Ruby, Go, CI/CD
2w
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Senior Cloud Infrastructure Engineer, Technical Delivery, Public Sector
Reston or Austin or Boulder
$153k-$222k/yr OnsiteFull Time
6+ YOEBachelor's in CS or equivalent; 6+ years in secure cloud solutions; automation/DevOps; programming in Python/Java/Go/C++; IT security practices; active Top Secret clearance.
Python, Java, Go, C, C++, VMware, GKE, GCP, Cloud Infrastructure, CI/CD, IAM, Data Encryption
2mo
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Advisory Software Engineer
Boulder, Colorado, United States
$93k-$110k/yr OnsiteFull Time
5+ YOEMS in CS/CE/EE or related field; 5+ years in software development; strong C/C++, Rust, Python; Linux IPC; AI/ML experience; Agile; travel up to 10%
C++, Rust, Python, Git, CI/CD, SQL, Java, JavaScript, AWS, Django, ReactJS, Linux
2mo
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Senior Engineer II - Software Platform
Boulder, Colorado, United States
OnsiteFull Time
7+ YOEBA/BS in CS/CE/EE/Physics and 7-8 years software engineering; Linux OS updates, CVE patches, automation, scripting; distributed VCS; US citizenship; TS/SCI preferred or able to obtain; strong OS/networking knowledge; build and release automation.
Bash, Python, Linux, Red Hat Linux, CI/CD, Yocto Project, BitBake, Kernel configuration, U-Boot, Secure boot, Device provisioning, Git, upstream patches
3w
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IT Corporate Senior Systems Engineer
Austin or Durham or Kansas City or Lakewood or Salt Lake City or Sunnyvale
$136k-$169k/yr HybridFull Time
8+ YOE8+ years enterprise IT systems engineering; 5+ years Google Workspace; macOS/Apple MDM (Kandji/Iru); Microsoft Intune; SaaS deployment; Bachelor's degree or equivalent.
Google Workspace, Kandji, Iru, Microsoft Intune, Python, PowerShell, GAM, CrowdStrike, CatchPoint, GCP Cloud CLI, Okta, Entra ID
3mo
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Experienced Software Engineer
Chicago or London or New York City or Austin or Boulder or Seattle
$200k-$300k/yr OnsiteFull Time
3+ YOEBachelor's or Master's in CS/Engineering; experience at top-tier firm; Python or C++; strong data structures and communication.
Python, C++, Data Structures, Algorithms, Distributed Systems, Debugging, Software Development Lifecycle
1mo
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Senior Security Operations Engineer
Los Angeles or New York City or Boulder or St. Petersburg
$138k-$155k/yr HybridFull Time
5+ YOE5+ years in security engineering/operations; cloud Linux; AWS and Snowflake; CI/CD with SAST tools; security frameworks; tooling Tenable, SentinelOne, Sumo Logic; Terraform; Go/Python; 3+ yrs containers; security by design.
AWS, Snowflake, Tenable, SentinelOne, Sumo Logic, CodeQL, SonarQube, Terraform, Go, Python, Shell, Docker, Kubernetes
1w
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Software Engineer Lead - GPU Platform Engineer
Pittsburgh or Strongsville or Denver or Birmingham or Dallas or Lakewood or Phoenix
$55k-$159k/yr OnsiteFull Time
3+ YOELead design and operation of large-scale GPU platform infrastructure; Linux, NVIDIA GPUs, Kubernetes, Python, CI/CD, HPC, containerized workloads.
Linux, NVIDIA GPUs, Docker, Kubernetes, OpenShift, Python, Slurm, Helm, JupyterHub, CI/CD
2w
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Algorithms Software Engineer - Level 3 or 4
Boulder, Colorado, United States
$114k-$213k/yr OnsiteFull Time
5+ YOEBachelor’s degree in STEM with advanced experience; Senior/Principal level requires 8/5+ years respectively; Secret DoD clearance with potential upgrade; 10% travel; Linux; Modern C++ (20+); Python; Git/CMake; strong math background.
Linux, C++, Python, Git, CMake
3w
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AI Software Engineer: Intelligent Data Infrastructure (San Jose, CA, US, 95128)
San Jose or Boulder or Pittsburgh or Raleigh
$131k-$195k/yr HybridFull Time
8+ YOE8+ years in software development; strong Golang, Python, C/C++; Linux kernel, file systems, distributed systems; AI/ML infra knowledge.
Golang, Python, C/C++, Linux, Kubernetes, GPU computing, Distributed systems, Storage systems
3w
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AI Software Engineer: Intelligent Data Infrastructure (San Jose, CA, US, 95128)
San Jose or Boulder or Pittsburgh or Raleigh
$131k-$195k/yr HybridFull Time
8+ YOE8+ years software development; expert in Golang, Python, C/C++; Linux kernel and distributed systems; AI/ML infra familiarity; strong problem solving and collaboration.
Golang, Python, C/C++, Linux, Kubernetes, GPU
2mo
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Staff AI Engineer
Boulder or Charlotte or United States
$190k-$225k/yr HybridFull Time
3+ YOE3+ years in Generative AI/LLMs in production; 6+ years ML; multi-agent systems; Python; distributed systems; cloud; observability; reliability safeguards; startup experience a plus.
Python, Pydantic AI, Agent Harness, Tool-Calling, Code Execution, AWS, GCP, Azure, LLM, Vector Databases
1mo
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Artificial Intelligence Software Engineer
Westminster, Colorado, United States
$171k-$235k/yr OnsiteFull Time
5+ YOE5+ years of professional software engineering on production systems; full-stack with Python, React, AWS/Azure; AI tooling experience; strong systems thinking.
Python, React, AWS, Azure, Cursor, GitHub Copilot, Gemini CLI
5d
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Staff Software Engineer (Boulder, CO)
Boulder, Colorado, United States
HybridFull Time
8+ YOE8+ years software engineering; expert C++ (C++20+); Python for backend; Linux, Docker, Git; architecture ownership; agentic coding tools; willing to travel; Boulder/Denver resident.
C++, Python, Linux, Docker, CMake, Git, ROS 2, MoveIt, gRPC, WebSocket, TypeScript, React
1mo
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Senior Thermal Engineer I
Westminster, Colorado, United States
$120k-$161k/yr OnsiteFull Time
4+ YOEBS/MS in Mechanical/Thermal/Aerospace engineering; 4+ years in thermal design; expertise in electronics/PCBA, thermal analysis; proficient in ANSYS, Thermal Desktop, SolidWorks; strong communication.
ANSYS, Thermal Desktop, SolidWorks, Matlab, Python
6d
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DevOps Engineer
White Plains or Conyers or Roanoke or Independence or Hartford or Savannah or Alexandria or Greensboro or Charleston or Missoula or Charlotte or Huntsville or Hartford or Miami or Tallahassee or Albany or Gainesville or Columbus or Boston or San Antonio or Dallas or Denver or Phoenix or San Francisco or Chicago or Nashville or Portland or Charlotte or Houston or Wilmington or Lexington or Tampa or Baltimore or Raleigh or Las Vegas or Cary or Irvine or Brookfield or Shreveport or Greenville or Van Nuys or Minneapolis or Red Bank or Jacksonville or Seattle or Sarasota or Kennesaw or Palm Beach or Towson or Sacramento or Dayton or Broomfield or Golden or Princeton or Omaha or Oklahoma City or Chesterfield or Schaumburg or Suffolk or Jupiter or Carmel or Canonsburg or Buffalo or Schaumburg or Philadelphia or Schaumburg or Sunrise or St. Louis or Los Angeles or Atlanta or Gulfport or Norwalk or South Portland or Metairie or Virginia Beach or Edina or Richmond or Southfield or Cleveland or Milwaukee or Chattanooga or Fort Worth or Rochester or Grand Forks or Detroit or Jersey City or Boise or Portland or San Ramon or Easley or Duluth or Glenville or Syracuse or West Palm Beach or Cary or Irvine or Brookfield or Shreveport or Greenville or Los Angeles or Atlanta or Orland Park or Columbia or Elmhurst or Portland or San Diego or San Ramon or Myrtle Beach or Gainesville or Hartford or Allentown or Macon or Tampa or Saint Petersburg or Irvine or Raleigh or San Ramon or Lewisville
$77k-$134k/yr RemoteFull Time
5+ YOE5+ years software development; cloud (Azure/AWS); CI/CD (Azure DevOps, GitHub Actions); scripting (Python, Bash, PowerShell); Git; strong communication; delivery track record.
Azure, AWS, Terraform, Azure Bicep, Docker, Kubernetes, Git, Azure DevOps, GitHub Actions, Python, Bash, PowerShell
2w
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Lead Software Engineer
Louisville, Colorado, United States
$135k-$165k/yr OnsiteFull Time
7+ YOE7+ years in software development; strong Python and Go; design of distributed systems; database experience (SQL/NoSQL); cloud-native, microservices; API integration; Git workflows.
Python, Go, Kubernetes, Docker, Git, SQL, NoSQL
1mo
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Network Engineer
Reston or New York City or Seattle or San Jose or Boulder or Chelmsford or Liberty Lake or New York or Spokane
$111k-$167k/yr RemoteFull Time
7+ YOESenior Network Engineer with 7+ years in large-scale, multi-region networks; FedRAMP experience preferred; strong automation and cloud networking skills.
Python, Ansible, AWX, Git, BGP, OSPF, JunOS, EOS, NX-OS, IOS-XE, Cloud networking, Netcat, Ping/ICMP
HiringCafe market data
Senior Python Developer Jobs market signals in Keystone, CO, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
150+
Hiring companies
51
Fresh sample
52% new in 30d
Salary visibility
89% show pay
Companies appearing in this market
BAE SystemsAtom ComputingGoogleLockheed MartinLoft OrbitalMicrochip TechnologyNorthrop GrummanSciTec
Work location mix in visible results
Onsite: 53Hybrid: 25Remote: 4