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Senior Python Developer Jobs in Lancaster, CA, US
430+ senior python developer jobs from 160+ companies hiring in Lancaster, CA, US.
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Senior Test Automation Engineer, Python
Burbank or Walnut Creek or Portland
$128k-$187k/yr HybridFull Time
5+ YOE5+ years in software development or test automation; expert Python; experience automating tests in virtualized environments; cross-platform desktop/mobile testing; CI/CD integration; strong troubleshooting.
Python, Qt, Docker, Git, Windows, Linux, CI/CD
2w
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Senior Software Developer
Woodland Hills, California, United States
$155k-$175k/yr HybridFull Time
5+ YOEBachelor's degree in CS/IT; 5+ years as a software developer; strong Python/Java/SQL; experience with ALIP/annuity platforms; API development; AWS; Agile.
Python, Java, SQL, PostgreSQL, Oracle, MS SQL Server, AWS, Spring, Spring Boot, REST, SOAP, JSON, CSV, Grafana, Splunk, ELK, OpsGenie, Astris, SQLAlchemy, psycopg2
1mo
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Senior Software Engineer
Ontario, California, United States
$85k-$127k/yr RemoteFull Time
7+ YOE7+ years in .NET development; strong experience with .NET Core, ASP.NET, C#, Python, MVC, Blazor, Razor, SQL Server; full-stack development; API integration; cloud (Azure preferred; AWS a plus); mentoring.
dotnet, NET Core, ASP.NET, C#, Python, MVC, Blazor, Razor, SQL Server, HTML, CSS, Azure, AWS, CI/CD, DevOps, APIs, Entity Framework, Design Patterns
2mo
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Senior Software Engineer, R&D
Pasadena or Santa Clara or Santa Rosa or Austin
$143k-$238k/yr HybridFull Time
5+ YOESenior software engineer with CAD/CAM frontend development on Windows, strong C++/Python, 5-10 years experience, frontend experience (Qt/QML, .NET, MFC), and collaboration with experts to deliver UI solutions.
C++, Python, Qt, QML, NET, MFC, Windows, CAD/CAM
1d
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Senior Fullstack Engineer
Mountain View or New York City or Los Angeles or San Francisco
$150k-$210k/yr OnsiteFull Time
4+ YOE4+ years software development experience; strong backend/full-stack skills (Python); frontend JS frameworks; containers and cloud knowledge; strong communication and collaboration.
Python, Go, Typescript, React, Docker, Kubernetes, Vue
2mo
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Senior Software Engineer
Glendale or San Francisco
$142k-$190k/yr HybridFull Time
5+ YOE5+ years in big data application development; strong Java/Scala/Python; experience with Spark/Flink and cloud infra; excellent collaboration and communication.
Spark, Flink, Kafka, Nifi, SingleStore, Databricks, Snowflake, Redis, Terraform, Kubernetes, Spinnaker, Airflow, AWS
4d
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Senior AI Software Engineer
Los Angeles, California, United States
$160k-$180k/yr HybridFull Time
3+ YOE3+ years full-stack AI application development; Bachelor's in CS/IS/engineering/data science; Python expertise; API development; React/TypeScript/Node.js; agile team experience.
Python, LangChain, Django, Flask, FastAPI, React, TypeScript, Node.js
2mo
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Senior Software Engineer
Glendale or San Francisco
$142k-$208k/yr HybridFull Time
5+ YOE5+ years in big data app development with Java/Scala/Python; experience with Spark, Flink, Kafka; cloud infra; SQL/NoSQL; strong collaboration.
Spark, Flink, Kafka, Nifi, Databricks, Snowflake, Airflow, Docker, Kubernetes, Terraform, AWS, SingleStore, Spinnaker, IAM, ALB
2w
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Senior Software Engineer
Redmond or New York or San Francisco or Los Angeles
$120k-$235k/yr OnsiteFull Time
4+ YOE4+ years engineering experience; proficient in C/C++/C#/Java/Python; Bachelor's in Computer Science or related field.
C, C++, C#, Java, JavaScript, Python, Go, Rust
1mo
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Senior Full Stack Engineer
Beverly Hills or Los Angeles
$120k-$150k/yr HybridFull Time
5+ YOE5+ years software development; backend and frontend; agile; cloud infrastructure; REST APIs; BS in CS/Engineering; proficient in Python/Node.js/JS; AWS/GCP; Salesforce Marketing Cloud a plus.
Python, Ruby, Node.js, Go, JavaScript, TypeScript, REST, CI/CD, AWS, GCP, Salesforce Marketing Cloud
1w
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Senior Applied AI/ML Engineer
Santa Monica or Lower Manhattan or San Francisco or Los Angeles
$180k-$200k/yr HybridFull Time
Senior AI/ML engineer with product experience; able to ship production AI systems; strong Python, ML, and system design.
Python, FastAPI, LLM, Agent workflows, Model evaluation
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Senior Software Engineer, GeniusIQ
Los Angeles or New York City
$175k-$220k/yr HybridFull Time
Senior software engineer to design, build, and operate real-time data systems powering GeniusIQ; collaborate with CV and ML teams; own end-to-end features across the stack.
Rust, Elixir, TypeScript, Go, C++, Python, PostgreSQL, Relational databases, React, Three.js, HTML5 Video, Canvas, REST, GraphQL, gRPC, AWS, Temporal.io, Docker, Kubernetes, Pulsar, RabbitMQ, WebAssembly
2mo
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Senior Data Engineer
Los Angeles, California, United States
$185k-$200k/yr OnsiteFull Time
6+ YOESenior data engineer with 6+ years in data engineering, SQL/Python, data warehouses, ETL/ELT, cloud, and BI tools; leadership experience preferred.
Snowflake, Redshift, BigQuery, Databricks, dbt, Apache Airflow, Looker, Tableau, Power BI, SQL, Python, Spark, Delta Lake
1mo
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Software Engineer, Senior (E3_PA_Multi)
Palmdale, California, United States
OnsiteFull Time
Bachelor's degree in a relevant field; C/C++; Linux/RTOS; software development lifecycle; US citizen; Secret clearance required within 5 years.
C, C++, Linux, RTOS, Python, Git, Gitlab, JIRA, Jenkins, Confluence, CMake, MATLAB
2mo
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Senior Software Engineer, R&D
Pasadena or Santa Clara or Santa Rosa or Austin
$143k-$238k/yr OnsiteFull Time
5+ YOEBachelors or Masters in CS or technical field; 5-10 years software development; strong C++ and Python; CAD/CAM frontend in Windows; experience with Qt/QML, .NET, MFC; cross-platform; 3D geometry knowledge a plus.
C++, Python, Qt, Qt/QML, .NET, MFC, 3D geometry
1mo
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Senior Platform Engineer
Los Angeles, California, United States
$165k-$215k/yr HybridFull Time
8+ YOE8+ years building distributed/platform systems; production Kubernetes/EKS ownership; cloud networking; proficiency in Go/TypeScript/Python/Java; strong collaboration and documentation skills.
Kubernetes, EKS, mTLS, certificate automation, PKI, SPF/SPIRE, Terraform, CDK, GitOps, Argo, Flux, Cilium, Envoy, Gateway API, K8s, CRDs, OPA, Kyverno, DNS/CoreDNS, Terraform, CNI, eBPF
3w
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Senior Backend Engineer - AI Product
Framingham or Los Angeles or Seattle
$165k-$215k/yr RemoteFull Time
5+ YOE5+ years backend experience; 3+ years Python; strong API, DB, and async framework skills; experience with AI tooling and LLM integration
Python, FastAPI, PostgreSQL, SQLAlchemy, Celery, Redis, Docker, Terraform, LangChain, LangGraph, Anthropic Claude, OpenRouter
1mo
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Application Developer, Senior
Oakland or Long Beach or El Dorado Hills or Lodi or Rancho Cordova or Redding or San Diego or Woodland Hills
$103k-$154k/yr HybridFull Time
5+ YOE5+ years full stack development; BA/BS; front-end frameworks; backend APIs in .NET/Java/Node.js/Python; SQL/NoSQL; cloud-native (Azure preferred); Docker; IaC; CI/CD; AI coding tools; healthcare experience preferred.
React, Vue, Angular, JavaScript, TypeScript, .NET, Java, Node.js, Python, SQL, MS SQL Server, Oracle, NoSQL, REST, Azure, AWS, GCP, Docker, Ansible, Bicep, ARM, Terraform, GitHub, GitLab, Bitbucket, Git, Copilot, Cursor, Claude, Epic
4w
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Senior Salesforce Developer
Chicago or Los Angeles or New York or Oakbrook Terrace or Sacramento or San Francisco or South Bend or San Jose or Tampa or Atlanta or Boston or Columbus or Dallas or Denver or Fort Lauderdale or Grand Rapids or Houston or Austin or Charlotte or Indianapolis
$109k-$222k/yr HybridFull Time
5+ YOE5+ years Salesforce experience; proficient in Apex, Visualforce, Aura, LWC; strong frontend skills; Salesforce API; certifications preferred
Salesforce, Apex, Visualforce, Aura Components, Lightning Web Components, Salesforce API, Heroku, AWS, Python, Node.js
2mo
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Senior AI Software Engineer
Los Angeles, California, United States
$160k-$180k/yr HybridFull Time
3+ YOE3+ years full-stack AI application development; Python; React/TypeScript/Node.js; agile teams.
Python, LangChain, Django, Flask, FastAPI, React, TypeScript, Node.js
2mo
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Senior Applied AI Engineer
Denver or Chicago or East Rutherford or Los Angeles or New York or Phoenix or San Francisco or Seattle
$125k-$186k/yr OnsiteFull Time
8+ YOE8+ years software engineering; expert Python; strong AWS; data modeling; LLM evaluation; experience with agentic systems and enterprise AI patterns; Bachelor's in CS/Engineering or equivalent.
Python, AWS, SQL, LLM, Dataiku, OpenAI
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Senior Staff Software Engineer
Los Angeles, California, United States
$200k-$260k/yr OnsiteFull Time
8+ YOE8+ years backend software engineering; distributed systems; AWS; Python/Node; REST APIs; Docker; Kubernetes; Postgres/Redis/time-series DBs; observability; scaling; eager to work in Los Angeles.
AWS, GCP, Python, Node, TypeScript, REST, Docker, Kubernetes, Postgres, Redis, HL7, FHIR, SFTP, webhook
1mo
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Senior Software Engineer - Edge-Services Security
New York or Los Angeles or Aliso Viejo
$200k-$250k/yr HybridFull Time
Expert level AWS edge/networking, IaC, bot management; strong Python/Go/TS/Java; scalable, secure edge infra; zero-trust.
Terraform, AWS CloudFront, Global Accelerator, WAF, Route53, Shield, Lambda@Edge, edge compute, bot management, Python, Go, TypeScript, Java
1mo
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Senior Backend Software Engineer, Rodeo
San Francisco or Los Angeles or Oregon or California or Washington
$145k-$190k/yr HybridFull Time
7+ YOE7+ years backend systems, Python, cloud (AWS/GCP), microservices, video processing tools, and ML model integration.
Python, AWS, GCP, Docker, Kubernetes, FFmpeg, SageMaker, Triton, TorchServe
2w
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Senior Backend Engineer
Los Angeles, California, United States
$150k-$195k/yr HybridFull Time
6+ YOE6+ years backend engineering; strong Node.js, TypeScript, PostgreSQL; experience building scalable eCommerce/online marketplaces; cloud (AWS/GCP); Docker/Terraform; AI coding tools; fast-moving startup environment.
Node.js, TypeScript, PostgreSQL, AWS, GCP, Docker, Terraform, GitHub Copilot, Tabnine, Python, APIs
2mo
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Senior Platform Engineer
Arvada or Los Angeles or San Francisco or Seattle or Washington
$145k-$186k/yr HybridFull Time
3+ YOE3+ years in reliability, systems, DevOps, infrastructure, or platform engineering; Bachelor's degree; ability to obtain security clearance; ITAR eligibility.
Kubernetes, Terraform, Python, New Relic, DataDog, Splunk, AWS CloudWatch, GitHub Actions, Auth0, Okta, Git, VPN, NLB/ALB, TLS, CDN
1mo
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Senior ML Engineer
Los Angeles, California, United States
$180k-$200k/yr RemoteFull Time
4+ YOE4+ years in ML/optimization; strong ML & optimization fundamentals; production PyTorch; autonomous in ambiguous spaces; strong communication.
PyTorch, CUDA C++, Python
2mo
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Senior Software Engineer
Los Angeles, California, United States
$160k-$190k/yr OnsiteFull Time
6+ YOE6+ years software experience; AI-native workflow; Python backend with ORM and async; TypeScript/React/Next.js frontend; AWS multi-tenant SaaS; GraphQL API design.
Python, Next.js, TypeScript, React, GraphQL, PostgreSQL, AWS, pytest, Jest
1mo
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Senior Test Engineer, HITL
Los Angeles, California, United States
OnsiteFull Time
5+ YOE5+ years in test engineering, embedded systems, or systems-level development; strong C/C++/Python; experience with HITL/HIL testing; embedded interfaces; test automation and CI/CD.
C/C++, Python, I2C, SPI, UART, CAN, Ethernet, Oscilloscopes, Logic analyzers, Multimeters, Embedded Linux, RTOS
2mo
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Senior Software Engineer
Burbank, California, United States
HybridFull Time
5+ YOE5+ years of professional software engineering; strong Python with REST APIs; experience with AI/ML frameworks; data modeling, asynchronous programming, microservices; CI/CD; problem solving with AI use cases.
Python, FastAPI, Flask, Django, OpenAI, LangChain, Hugging Face, REST APIs, AWS, GCP, Azure, CI/CD
3d
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Senior Software Engineer (Burbank, CA, US, 91505)
Burbank, California, United States
$124k-$170k/yr OnsiteFull Time
7+ YOE7+ years software engineering; 5+ years with Go/Java/Python; experience with AI tools; 3+ years microservices; cloud experience (OCI, GCP); BS/MS in CS or related field.
Go, Java, Python, Docker, Kubernetes, Oracle Cloud Infrastructure (OCI), Google Cloud Platform (GCP), Cursor, Anthropic Claude
1mo
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Senior Site Reliability Engineer
Los Angeles, California, United States
$160k-$214k/yr OnsiteFull Time
5+ YOESenior SRE with 5+ years infra experience; Python/Go/C#/Typescript; Kubernetes, AWS + other cloud; IaC, CI/CD, SLO/SLI; strong Linux
Python, Go, C#, Typescript, Linux, Docker, Kubernetes, Terraform, CloudFormation, Pulumi, AWS, GCP, Azure, CI/CD, Observability, PostgreSQL, MySQL
1mo
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Senior Software Engineer - Automation
Las Vegas or Culver City
OnsiteFull Time
4+ YOE4+ years of software engineering or automation experience; proficiency in at least one compiled language and one scripting language; CI/CD experience; automated testing; interest in AI tooling.
C#, C++, Go, Rust, Java, Python, Bash, Jenkins, TeamCity, CircleCI, Horde
2d
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Senior Simulation Engineer
Los Angeles, California, United States
$160k-$200k/yr OnsiteFull Time
7+ YOEBachelor’s degree in CS, engineering, physics, or math; 7+ years’ related experience; coding in Python, Java, or C++.
Python, Java, C++
3w
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Senior Photonics Systems Engineer - TeraWave
Los Angeles or El Segundo or King County
$157k-$220k/yr OnsiteFull Time
Blue Origin: Develops reusable rockets and systems for human spaceflight.
7+ YOE7+ years in engineering of complex photonics/optics systems; leadership/architecture experience; strong hands-on with MATLAB/Python; space hardware experience preferred.
MATLAB, Python, LabVIEW, VPIphotonics, OptiSystem
6d
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Senior Data & AI Platform Engineer
San Ramon or Salt Lake City or Chicago or Philadelphia or Dallas or Denver or New York City or Century City or Garden City or Nashville or St. Louis or Bellevue or Woodland Hills or Irvine or Boca Raton or Downtown Los Angeles or Atlanta or Boise or San Jose or San Francisco or Austin or El Segundo
OnsiteFull Time
7+ YOE7+ years in Microsoft Cloud/DevOps; 3+ years enabling data/analytics platforms; AI/GenAI experience; strong security/governance; CSP operations; observability and cost optimization; PowerShell/Python scripting.
Azure DevOps, Fabric, Synapse, ADF, Databricks, Key Vault, Entra ID, RBAC, PIM, Conditional Access, Azure Monitor, Log Analytics, KQL, PowerShell, Python, MLOps
1mo
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Senior SW Engineer ACE (PCB Design),
Los Angeles or Seattle or Washington D.C.
$165k-$250k/yr OnsiteFull Time
5+ YOEMaster’s degree +5 years, or PhD +3 years; strong Python/C++ skills; CAD/CAE automation with SolidWorks/Creo/Ansys/COMSOL/Star-CCM+; CFD/FEA/SPICE experience; leadership and mentoring abilities.
Python, C++, SolidWorks, Creo, Ansys, COMSOL, Star-CCM+, ECAD Tools (Altium)
2mo
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Senior Product Software Engineer, Applied Technologies
New York or San Francisco or Los Angeles
$210k-$240k/yr HybridFull Time
8+ YOE8+ years software engineering; 2+ years product development in client-facing role; cross-functional collaboration; impact on real-world customers.
Docker, AWS, Google Cloud, Terraform, Python, React, Claude Code, Cursor, MCP (LLM integrations)
2w
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Senior AI Engineer
Los Angeles or New York
$170k-$200k/yr OnsiteFull Time
6+ YOE6+ years software engineering; 2+ years in production AI/LLM apps; strong Python; LLM APIs; data pipelines; Airflow; AWS; product-quality focus
Python, SQL, Snowflake, Airflow, AWS, GitHub, Datadog, OpenAI, Anthropic, TypeScript, React, Scala, Java
1mo
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Senior DevOps Engineer
Chatsworth, California, United States
$155k-$185k/yr OnsiteFull Time
5+ YOE5+ years DevOps/SRE or cloud infra; Azure; Linux; CI/CD; Terraform; Docker/Kubernetes; Python/JavaScript; observability tools.
Azure, Linux, Terraform, GitHub Actions, Azure DevOps, Docker, Kubernetes, Prometheus, Grafana, Datadog, Python, JavaScript
HiringCafe market data
Senior Python Developer Jobs market signals in Lancaster, CA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
430+
Hiring companies
160+
Fresh sample
32% new in 30d
Salary visibility
88% show pay
Companies appearing in this market
Keysight TechnologiesDisney2K VegasAscendiunBlue OriginK2 SpaceLockheed MartinMetropolis
Work location mix in visible results
Onsite: 50Hybrid: 38Remote: 7
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