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Genai Python Systems Engineer Jobs in United States
100+ genai python systems engineer jobs from 74 companies hiring in United States.
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GenAI Python Systems Engineer-Manager
Chicago or Raleigh or Charlotte or Cincinnati or Cleveland or Columbia or Columbus or Dallas or Baltimore or Rochester or Rosemont or Sacramento or Boston or St. Louis or Salt Lake City or San Antonio or San Diego or San Francisco or Silicon Valley or Seattle or Albany or Stamford or Tampa or Atlanta or Toledo or Austin or Houston or New York or Philadelphia or Phoenix or Portland or Raleigh or Greensboro or Hartford or Miami
$99k-$232k/yr OnsiteFull Time
5+ YOE5 years of experience; strong skills in Python, SQL, Docker; cloud experience (AWS/Azure/GCP); data architecture and engineering; leadership responsibilities.
Python, SQL, Docker, AWS, Azure, GCP, Terraform, CloudFormation, LLM, Prompt Engineering, Snowflake, Databricks
3d
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Lead GenAI Cloud Developer
United States
$94k-$149k/yr RemoteFull Time
5+ YOELead GenAI cloud developer for ElasticGPT; advanced agentic capabilities; Python/TypeScript; Elasticsearch; Kubernetes; cloud infra; GenAI systems.
Python, TypeScript, PyTorch, TensorFlow, Hugging Face, Elasticsearch, Kubernetes, Docker, LangGraph, LangSmith, n8n, OpenTelemetry, OpenAI, Anthropic, Vertex AI, BM25, vector search, Confluence, Jira, GitHub, ServiceNow
6d
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Senior iCloud Efficiency Engineer (GenAI & Agentic Systems)
Culver City or San Diego or San Francisco or Seattle
HybridFull Time
5+ YOE5+ years in software or infrastructure engineering; GenAI/LLM experience; strong Python/Java; leadership in engineering practices; cloud ops and observability expertise.
Python, Java
2mo
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GenAI Developer – Credit Risk and Fraud Platform (Banking)
United States
RemoteFull Time
Strong Python backend/AI experience; LLM/GenAI development; LangChain/LangGraph; FastAPI/Flask REST APIs; RAG architectures and vector databases; prompt engineering and agent design; secure, regulated, high-availability systems; English proficiency.
Python, LangChain, LangGraph, FastAPI, Flask, REST API, LLM, Vector database
1mo
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GenAI Platform Engineer
Seattle or Arlington
$100k-$203k/yr RemoteFull Time
Python experience, retrieval/vector search, grounding AI in enterprise data; strong observability/SRE for AI; optimize latency, cost; cloud or on‑prem; able to own production systems end‑to‑end; US citizenship.
Python, Retrieval systems (pgvector Milvus OpenSearch), Terraform, CI/CD, Cloud services, SRE, FinOps, Grounding AI in enterprise data
1w
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Principal GenAI Inference Optimization Engineer
San Jose, California, United States
$210k-$360k/yr OnsiteFull Time
GenAI inference optimization, GPU performance, and large-scale serving systems experience; strong kernel/runtime/framework collaboration; Python and systems languages proficiency.
PyTorch, JAX, TensorFlow, Triton, TensorRT-LLM, vLLM, SGLang, CUDA, HIP, Python, C++, KV-cache, profiling tools
3d
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GenAI Engineer - Senior Associate - 68644792
Dallas or New York
$65k-$90k/yr OnsiteFull Time
5+ YOE5 years software development; 3 years ML; cloud and AI systems experience; AWS and LLM familiarity.
Python, Java, C/C++, Go, AWS, Terraform, CloudFormation, SageMaker, ECS, EKS, Lambda, S3, DynamoDB, Redshift, Step Functions
1mo
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Senior Software Engineer / Solutions Architect (Python & GenAI)
United States
RemoteFull Time
Provectus: Builds and deploys custom artificial intelligence and data solutions.
7+ YOESenior Software Engineer or Solutions Architect with 7+ years Python and GenAI experience; builds production AI, RAG systems, and LLM-based solutions; strong design, presales, and client-facing skills.
Python, FastAPI, Django REST, Flask, Docker, Kubernetes, AWS SageMaker, AWS Bedrock, AWS Lambda, AWS ECS, AWS S3, AWS SQS, AWS ECR, React, Vue, OpenAI API, Anthropic API, Claude Code, AWS Certified, Cloud Certifications
2mo
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Lead Engineer - GenAI
Brooklyn Park or Sunnyvale
$132k-$286k/yr HybridFull Time
7+ YOESoftware development experience; GenAI focus; strong Java/Python skills; LLM experience; scalable systems.
Java, Python, PostgreSQL, OpenSearch, S3, LLM ecosystems, LangChain, LangGraph, Google GenAI
3w
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Senior GenAI Backend Platform Developer
Rockville or Jersey City or Denver or San Francisco or New York
HybridFull Time
5+ YOESenior GenAI backend developer with 5+ years of experience in cloud-native systems, AWS, CI/CD, and secure software practices.
AWS Bedrock, AWS S3, AWS Fargate, AWS Lambda, AWS Step Functions, Jenkins, Git, Docker, Python, FastAPI
2mo
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Software Engineer, GenAI
San Francisco or New York City or Pittsburgh
$255k-$300k/yr HybridFull Time
3+ YOE3+ years production systems experience; GenAI/LLM experience; Python proficiency; experience with retrieval, tool-use, and agentic workflows; strong evaluation and deployment skills.
Python, LangChain, LlamaIndex, Vector DB, API tooling
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Principal Engineer - GenAI Team
New York, New York, United States
$157k-$230k/yr OnsiteFull Time
10+ YOEML/AI, GenAI solutions, multi-tier systems, Python, APIs, databases; strong collaboration; 10+ years preferred.
Python, REST API, Databases, ML Frameworks, Generative AI Tools
1mo
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Software Engineer (AI/GenAI Platforms)
Charlotte or Chicago or Dallas or Fort Worth
$85k-$145k/yr HybridFull Time
Experience with Python and Java; AI/GenAI and ML systems; data pipelines; production-grade AI/ML; distributed processing; integration into enterprise systems.
Python, Java, LangChain, LlamaIndex, Semantic Kernel, Hugging Face, OpenAI, AWS Bedrock, Azure OpenAI, Kafka, Datadog, CloudWatch, MongoDB Atlas, DocumentDB, SageMaker, Vector Databases
1w
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Integration Engineer Enterprise Systems
Bellevue or Livingston or New York or San Francisco or Sunnyvale
$165k-$242k/yr HybridFull Time
Experience building integrations with Workato; strong Finance and Supply Chain systems expertise; RESTful APIs and event-driven architectures; Python/JavaScript; cloud environments; DevOps/CI/CD; GenAI tools.
Workato, Boomi, REST APIs, Python, JavaScript, Cloud Platforms (AWS, Azure, GCP), DevOps, CI/CD, GenAI tools
1mo
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Staff Machine Learning Engineer, GenAI Platform
United States
$253k-$355k/yr RemoteFull Time
10+ YOEExtensive experience in distributed ML systems and GenAI/LLM infra; 10+ years in production software; strong MLOps, Kubernetes, Python/Go; expertise with distributed training frameworks.
Kubernetes, Docker, Python, Go, CUDA, DeepSpeed, Megatron-LM, TensorRT-LLM, Ray, MLflow
3w
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Senior Software Engineer – GenAI Infrastructure & Agent Systems for Engineering Efficiency
Mountain View, California, United States
$160k-$241k/yr OnsiteFull Time
4+ YOE4+ years in software engineering; strong Python, C++, or Go; cloud infra (GCP/AWS), Kubernetes, CI/CD; building production AI agent systems and automation.
Python, C++, Go, GCP, AWS, Kubernetes, CI/CD
1w
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Machine Learning Infrastructure Engineer, GenAI Technology
United States
$180k-$300k/yr HybridFull Time
3+ YOEBachelor’s or Master’s in CS/EE or related field; 3–7 years in scalable compute/ML infrastructure; distributed systems, Kubernetes, cloud platforms; ML tools (MLflow, Ray, Airflow, Kubeflow, Terraform); Python and systems programming; strong debugging and optimization skills.
Kubernetes, Terraform, MLflow, Ray, Airflow, Kubeflow, AWS, GCP, Azure
3w
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Senior Software Engineer, GenAI (Chicago, IL, US)
Chicago, Illinois, United States
$140k-$150k/yr HybridFull Time
7+ YOE7+ years in AI/ML production systems; 5+ years full-stack software engineering; experience with GenAI, RAG, MCP, embeddings; strong Python, FastAPI, cloud (AWS/Azure); LangChain/LangGraph; Docker/Kubernetes; MLflow; production-grade APIs and scalable infrastructure.
Python, FastAPI, PyTorch, TensorFlow, LangChain, LangGraph, MCP, AWS, Azure, Docker, Kubernetes, MLflow
4d
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AI Research Engineer
United States
$200k-$250k/yr RemoteFull Time
5+ YOE5+ years software engineering; 1+ year GenAI in production; strong Python; experience with agent frameworks and memory systems; able to translate research into production systems.
Python, LLMs, Agent frameworks, Memory / retrieval systems, Vector databases, Evaluation pipelines
1mo
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Senior Machine Learning Engineer
United States
$150k-$180k/yr RemoteFull Time
3+ YOESenior ML engineer to design, productionize GenAI systems, and mentor engineers.
Python, AWS, Terraform, CI/CD frameworks
5d
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Principal Software Engineer, Cloud
San Diego, California, United States
$180k-$230k/yr HybridFull Time
12+ YOE12+ years in software engineering/cloud architecture; proven leadership; strong Go/Python; GCP, Kubernetes, Terraform/Pulumi; distributed systems; GenAI tooling.
Go, Python, Google Cloud Platform, Kubernetes, Docker, Terraform, Pulumi, Pub/Sub, Kafka, Bazel
2w
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Lead Software Engineer, GenAI Products - SVP - Irving
Irving, Texas, United States
$156k-$234k/yr HybridFull Time
Proven technical project leadership; hands-on production services; polyglot across Python/Java/Go/TypeScript; distributed systems design; CI/CD; Postgres; OpenShift/Kubernetes.
Python, Java, Go, TypeScript/Node.js, PostgreSQL, OpenShift, Kubernetes, GitHub, Tekton, Harness, Airflow, Dagster
2w
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Senior Software Engineer, Self-Serve Intelligence
San Francisco or New York
$185k-$222k/yr HybridFull Time
5+ YOE5+ years software engineering; backend systems, microservices; GenAI/AI experience; strong API design; Python a plus.
Python, APIs, GenAI, LLMs, Microservices, Backend services
1w
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Software Engineer, AI System Hacker, GenAI, DeepMind
Mountain View, California, United States
$174k-$252k/yr OnsiteFull Time
5+ YOEBachelor's in CS/AI or related field; 5 years full-stack exp; backend in Java/Python/C++; frontend JS/TS/HTML/CSS; UI design; cross-functional collaboration.
Java, Python, C++, JavaScript, TypeScript, HTML, CSS
1mo
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Machine Learning Engineer
Denver or Remote
$1200k-$1500k/yr RemoteFull Time
2+ YOEExperience delivering ML/NLP solutions, production ML systems, Python backend, GenAI/LLMs, and HIPAA-aware data handling.
Python, PyTorch, OpenAI, Anthropic Claude, Google Gemma, GenAI, LLMs, NLP, NLG
2mo
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Senior Software Engineer, AI Platform
United States
$131k-$198k/yr RemoteFull Time
6+ YOE6+ years backend/platform software engineering; GenAI in production; distributed systems; Python/Java/Go; GenAI frameworks; US work authorized.
Python, Java, Go, LangChain, OpenAI SDK
2mo
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Senior/Staff Machine Learning Engineer, General Agents, Enterprise GenAI
New York or San Francisco or Seattle
$218k-$273k/yr HybridFull Time
5+ YOE5+ years building and deploying ML/AI systems; strong Python; experience with models, tools, APIs, and production deployments; excellent cross-functional collaboration.
Python, LLMs, APIs, Databases, Tools and frameworks for agent systems
6d
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AI Full Stack Engineer – Agentic Systems & Ontology
Bethesda or Grand Prairie or King of Prussia or Littleton or Moorestown or Orlando
$109k-$217k/yr RemoteFull Time
Full-stack development with Python and JS frameworks; knowledge graphs and ontologies; LLM/GenAI experience; cloud and on-prem; US citizenship; degree in CS/IT/Engineering/AI/ML or related.
Python, Java, C++, Go, JavaScript, React.js, Angular, REST, OpenAPI, JSON-Schema, GitOps, Cloud, AWS, RDS, PostgreSQL, Bedrock, EC2, S3, Knowledge Graphs, Ontologies, KG tools, Pydantic AI, LangChain, LangGraph, Terraform, Ansible, CI/CD, GitLab, Jenkins, Kubernetes, OpenShift, Vector Databases, Semantic Search, RDF, OWL, SPARQL, Ontop
4d
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Sr Engineer, AI Solutions
Irvine, California, United States
$130k-$168k/yr OnsiteFull Time
4+ YOEMaster's in CS/Data Science or 6+ years AI/ML system design experience; 4+ years AI/ML engineering; Python and ML libraries; GenAI/LLMs; cloud and MLOps; healthcare familiarity.
Python, TensorFlow, PyTorch, Hugging Face Transformers, LangChain, GenAI, Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), SQL, NoSQL, AWS, GCP, Docker, Kubernetes
1mo
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Senior Software Engineer, Backend - Platform (Compliance Automation)
United States
$186k-$219k/yr HybridFull Time
5+ YOE5+ years in software engineering; microservices; system design; coding; Python or Go; GenAI/infrastructure familiarity.
Python, Go, Docker, PostgreSQL, MongoDB, GenAI frameworks
1mo
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Senior AI Product Engineer
McLean, Virginia, United States
OnsiteFull Time
5+ YOESenior AI product engineer with 5+ years building GenAI/LLM systems, Python, LangChain, and collaboration with design/product teams.
Python, LangChain, LlamaIndex, DSPy, LangChain, Docker, Kubernetes, AWS, Azure, GCP, Retrieval augmented generation, LLMs
3w
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AI or ML Engineer - Remote
Eden Prairie, Minnesota, United States
$99k-$176k/yr RemoteFull Time
5+ YOE5+ years in ML engineering/MLOps with cloud, Python, and distributed systems; strong ML lifecycle and GenAI experience.
Python, PyTorch, TensorFlow, scikit-learn, MLflow, Kubeflow, SageMaker, Azure ML, GCP Vertex AI, Docker, Kubernetes, AWS SageMaker, Spark, Ray, Airflow, Dagster, Prefect, LangChain, LlamaIndex, Semantic Kernel, Cursor, Claude Code, Replit
2w
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Principal Engineer, MLE, SMAI
Boise, Idaho, United States
OnsiteFull Time
9+ YOEDeep expertise in ML/AI model training, distributed systems, and GenAI for manufacturing; 9+ years in data pipelines, big data, and ML/AI deployments.
PyTorch, DeepSpeed, Megatron-LM, LangChain, LangGraph, LlamaIndex, AutoGen, CUDA, Triton, vLLM, TensorRT-LLM, Slurm, Ray, KubeFlow, Jenkins, Git, Docker, Kubernetes, Snowflake, Google Cloud, Nsight Systems, PyTorch Profiler, Python, Java, CI/CD, DDP, FSDP, LoRA, QLoRA, PEFT
3w
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Lead Software Engineer - MLIO Virtual Conversation assist
Columbus or Wilmington
HybridFull Time
5+ YOE5+ years in software engineering with system design, development, testing and operations; strong Java or Python; practical AWS experience; Terraform; knowledge of AI/ML concepts and GenAI; experience with large language models and AWS Bedrock.
Terraform, AWS, Bedrock, SSE, WebSocket, Java, Python, AI/ML, GenAI, Terraform for Infra Deployment, ECS, EKS, AWS Cloud Services
2w
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Staff Software Engineer, Merchants & Ads Review
San Francisco or Palo Alto
$208k-$365k/yr HybridFull Time
8+ YOE8+ years of software engineering; staff-level IC; ads/commerce/trust & safety/GenAI experience; strong systems design and AI integration.
Python, Machine Learning, GenAI, Full-Stack Development, Distributed Systems, SQL, NoSQL, Cloud
2w
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Senior Software Engineer - AI
Hoboken, New Jersey, United States
$140k-$160k/yr HybridFull Time
8+ YOEStrong software engineering experience with applied AI/GenAI systems; 8+ years in development; proficiency in Python; experience with distributed architectures and AI production readiness.
Python, Distributed Systems, LLMOps, Embeddings, Data Ingestion, Vector Databases
1mo
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Senior+ Backend Engineer
Brooklyn, New York, United States
$150k-$250k/yr OnsiteFull Time
5+ YOE5+ years backend experience with Python; FastAPI/asyncio; PostgreSQL and Redis; distributed systems; DevOps mindset; GenAI/LLM pipelines.
Python, FastAPI, Elixir/Phoenix, PostgreSQL, Redis, Docker
2w
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Principal Engineer, AI
Novi, Michigan, United States
$125k-$184k/yr HybridFull Time
8+ YOE8+ years of production software experience; ML/LLM experience; strong Python/Node.js; experience with AI/GenAI systems and cloud infrastructure.
Python, Node.js, FastAPI, NumPy, Pandas, scikit-learn, Pydantic, Jinja2, PyTorch, Transformers, TensorFlow, Keras, LangChain, LlamaIndex, Pinecone, FAISS, Weaviate, Milvus, pgvector, Snowflake, Delta Lake, BigQuery, MS Fabric, Docker, Kubernetes, Terraform, Datadog, Grafana, LangFuse, React, REST, GraphQL, AWS, S3, EC2, Lambda, CloudWatch, Fargate, EKS, ECS, Azure, GCP, Databricks, Terraform, CI/CD, Airflow, Kafka, SQL, PostgreSQL, DynamoDB, Elasticsearch
4d
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Senior Software Engineer
Eden Prairie, Minnesota, United States
$92k-$164k/yr RemoteFull Time
5+ YOESenior software engineer with ML/GenAI, cloud (Azure), Python, SQL; 5+ years Azure, 2+ years AI; strong ML fundamentals; experience building scalable AI systems.
Azure, Python, Pandas, NumPy, SQL, Hugging Face, LangChain
1mo
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Senior AI Engineer (Databricks)
Boston or United States
RemoteFull Time
7+ YOE7-10 years software engineering; 3-5 years ML/AI in high-velocity environments; 2+ years Databricks; Python, TensorFlow/PyTorch; GenAI experience; scalable distributed systems.
Databricks, Mosaic AI Gateway, Python, TensorFlow, PyTorch, RAG, SQL, MCP, API
HiringCafe market data
Genai Python Systems Engineer Jobs market signals in United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
100+
Hiring companies
74
Fresh sample
64% new in 30d
Salary visibility
75% show pay
Companies appearing in this market
AppleFitch GroupUnitedHealth GroupCitiBank of AmericaGoogleJPMorgan ChasePwC
Work location mix in visible results
Hybrid: 22Onsite: 18Remote: 16