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Lead Python Developer Jobs in Highlands Ranch, CO, US
100+ lead python developer jobs from 64 companies hiring in Highlands Ranch, CO, US.
2mo
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GIS Lead Developer
Denver, Colorado, United States
$92k-$118k/yr OnsiteFull Time
5+ YOE5+ years GIS development; Python, JavaScript/TypeScript, SQL; PostgreSQL/PostGIS; Snowflake; ArcGIS; data pipelines; UI/UX; cross-functional collaboration.
Python, JavaScript, TypeScript, SQL, PostgreSQL, PostGIS, Snowflake, ArcGIS, Dataiku, Leaflet, React, Git
2w
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Lead Software Engineer
Louisville, Colorado, United States
$135k-$165k/yr OnsiteFull Time
7+ YOE7+ years of software development; strong Python and Go; design of databases; distributed systems and microservices; real-time data pipelines; cloud-native development; API integration; Git workflows
Python, Go, SQL, NoSQL, Kubernetes, Docker, Git, APIs
1w
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Software Engineer Lead - GPU Platform Engineer
Pittsburgh or Strongsville or Denver or Birmingham or Dallas or Lakewood or Phoenix
$55k-$159k/yr OnsiteFull Time
3+ YOELead design and operation of large-scale GPU platform infrastructure; Linux, NVIDIA GPUs, Kubernetes, Python, CI/CD, HPC, containerized workloads.
Linux, NVIDIA GPUs, Docker, Kubernetes, OpenShift, Python, Slurm, Helm, JupyterHub, CI/CD
1mo
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Technical Lead - Software Developer, Data Foundry
San Francisco or San Diego or Boston or Louisville or Indianapolis
$152k-$244k/yr OnsiteFull Time
5+ YOE5–10+ years scientific software development; Python and another language; REST APIs, data pipelines, microservices; experience with scientific datasets.
Python, Java, C#, Go, TypeScript, Rust, SQL, REST APIs, Microservices, MLflow, Weights & Biases, Docker, Kubernetes, AWS, Azure, GCP, Prefect, Airflow, Nextflow, Postgres, Redshift, Snowflake, BigQuery, LIMS, ELN, Benchling, RDKit, Schrödinger, MOE, Git, Linux, Bash
1mo
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Software Engineer Lead
Herndon or Aurora
$135k-$216k/yr OnsiteFull Time
12+ YOEBachelor’s degree in Computer Science, Engineering, or related field; minimum 12 years of experience; TS/SCI with clearance eligibility; proficiency in Java, C++, Python; Jira and Confluence experience; leadership of technical teams; experience with DevSecOps, cloud, and distributed systems.
Java, C++, Python, Jira, Confluence, DevSecOps, Docker, Kubernetes, Cloud architectures (AWS, Azure)
2mo
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Lead Software Engineer (Back-End)
Westminster, Colorado, United States
$120k-$170k/yr HybridFull Time
5+ YOE5+ years in software development; strong web tech (C#, .NET); experience leading projects; 1+ year in cloud platforms (Azure, AWS, Snowflake); code review; mentoring; strong problem solving and communication.
C#, NET, SQL, JavaScript, Azure, AWS, Snowflake, Python
18h
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Lead Data Engineer
Denver, Colorado, United States
$135k-$160k/yr OnsiteFull Time
12+ YOELead data engineer with 12+ years in data engineering, strong SQL/Python, cloud platforms, ETL/ELT, data governance, and leadership.
SQL, Python, Cloud platforms, ETL/ELT, CI/CD, Data governance, Parquet/Delta/Iceberg
2w
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Lead Software Engineer
Louisville, Colorado, United States
$135k-$165k/yr OnsiteFull Time
7+ YOE7+ years in software development; strong Python and Go; design of distributed systems; database experience (SQL/NoSQL); cloud-native, microservices; API integration; Git workflows.
Python, Go, Kubernetes, Docker, Git, SQL, NoSQL
1w
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Lead Java Software Engineer
Phoenix or San Francisco or Chicago or Denver or Salt Lake City or Madison
$85k-$160k/yr RemoteFull Time
8+ YOE8+ years software development; Java/Spring Boot; cloud-based enterprise apps; strong analytical, communication, and independent working skills.
Java, Python, Spring Boot, MySQL, NoSQL, OpenSearch, Elasticsearch, Apache Camel, RabbitMQ, Data pipelines, AWS, Kubernetes, CI/CD, REST, SOAP, Microservices
1mo
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Software Engineer Lead (Boulder, CO, US, 80301)
Boulder, Colorado, United States
$104k-$188k/yr HybridFull Time
10+ YOELead software engineer with 10+ years in C++ on Linux; architect/design software, embedded systems; mentorship and technical direction.
C++, Linux, Embedded, Python, Google Test
1mo
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Lead Platform Data Engineer
Carmel or Golden
$131k-$205k/yr OnsiteFull Time
7+ YOE2+ MgmtSeven-plus years in data engineering with at least two years in a lead or staff capacity; strong data modeling, SQL, Python/Go/Java, dbt, and cloud data platforms.
Snowflake, Databricks, BigQuery, SQL, Python, Go, Java, dbt, Airflow, Terraform, CloudFormation, AWS, Azure, GCP, OpenAPI, AsyncAPI, Data Contracts
3w
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Lead Data Engineer
Cedar Rapids or Denver or Philadelphia
$107k-$135k/yr HybridFull Time
5+ YOELead data engineer role with 5+ years in data engineering, cloud/on-prem infrastructure, and BI; strong SQL, programming, and analytics skills.
Python, Java, SQL, Snowflake, AWS, Scala, Node.js
4w
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Lead GenAI Backend Platform Software Engineer
Rockville or Jersey City or Denver or San Francisco or New York City or Tysons
HybridFull Time
7+ YOE7+ years in software engineering; strong backend design; Python, FastAPI; cloud (AWS); LLMs; security; CI/CD; team leadership.
Python, FastAPI, AWS Bedrock, S3, Lambda, Step Functions, Fargate, Aurora, CI/CD, Git
3w
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Lead DevOps Engineer
Chicago or Coppell or Minneapolis or Tampa or Denver or Houston or Indianapolis or Kennesaw
$116k-$204k/yr RemoteFull Time
8+ YOE8+ years experience in DevOps/SRE with cloud infra, IaC, CI/CD; strong Python/.NET/Java background; leadership experience.
Terraform, Ansible, Jenkins, Azure, AWS, Git, CloudFormation, PowerShell, Bash, AKS, EKS, Docker
3w
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Lead Mission Engineer (DevOps)
Denver or Arlington or San Diego or Woburn or United States
$157k-$224k/yr HybridFull Time
7+ YOEBS in computer science or related field; 7+ years of DoD/IC software deployment experience; TS/SCI with eligibility; strong React/TypeScript/Python skills; DoD mission deployment experience.
React, TypeScript, Python, CI/CD, AWS, Docker, Kubernetes, Security monitoring, Incident response
1mo
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Software Engineer/ UI Tech Lead Level 5
Aurora, Colorado, United States
$177k-$266k/yr OnsiteFull Time
12+ YOETop Secret clearance with SCI eligibility; 12+ years software development; full‑stack experience; Agile; UI/UX focus; TS-SCI eligibility; experience with React/TypeScript; cloud and containerization preferred.
TypeScript, Node.js, React, Angular, Vue, Docker, Kubernetes, NestJS, Express, Redis, BullMQ, SQL, RxJS, GitLab, Python, Golang, AWS
3w
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Lead Sr Staff Software Engineer - Front End Fundamentals
Bellevue or Boulder or Chicago or Denver or Irvine or Los Angeles or New York or San Francisco or San Jose or Seattle or Ventura
$166k-$305k/yr HybridFull Time
13+ YOE1+ MgmtSenior frontend leadership role requiring 13+ years of software development, 1+ year of people management, strong TypeScript/JavaScript or other languages, cloud and distributed systems experience, and mentoring.
TypeScript, JavaScript, C#, Java, C, C++, Python, SQL, Scala
3w
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Lead Network Engineer
Littleton, Colorado, United States
$110k-$157k/yr OnsiteFull Time
10+ YOEBachelor's preferred; 10+ years experience in enterprise/service provider networking; CCNA/CCNP/CCIE and cloud/network certifications a plus.
BGP, ISIS, MPLS, Segment Routing, DNS, DHCP, IP Address Management, TACACS, ISE, VPN, Python, Bash, Ansible, Network automation
2w
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Lead Software Engineer - Search
Chicago or Peoria or Irving or Aurora
$128k-$209k/yr OnsiteFull Time
5+ YOE3+ MgmtLead data scientist with AI/ML search, NLP, vector search, leadership; strong Python; cloud platforms; agile.
Python, NumPy, SciPy, pandas, ML platforms, GitHub, AWS, Azure, GCP
1mo
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Senior/Lead QA Engineer
Boulder, Colorado, United States
$90k-$125k/yr OnsiteFull Time
5+ YOE5+ years software QA/testing; 2+ years in lead/senior QA; degree in engineering or CS; OS knowledge; Python scripting; regression testing; release management.
Python, Wireshark, TCP Dump, Regression testing tools, Release management tools
6d
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Senior Software Engineer, Level 3 - Embedded - Clearance Required
Littleton, Colorado, United States
$93k-$164k/yr OnsiteFull Time
Embedded software development experience; C/C++, Python; Linux; Agile; Top Secret/TS clearance required; ability to lead in a collaborative, multi-disciplinary team.
C/C++, Python, Linux, Agile
1mo
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Lead Machine Learning / Data Science Engineer
Denver, Colorado, United States
$90k-$200k/yr OnsiteFull Time
7+ YOE7+ years in data engineering and ML on cloud; leadership; Python/Scala; SQL/Spark; Docker; Snowflake/Databricks; ML systems and LLMs.
Python, Scala, SQL, Spark, Docker, Snowflake, Databricks, Azure SQL, Amazon RDS, Langchain, n8n, pydantic
1mo
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Engineer Senior Principal – Lead Mission Analyst
Broomfield or Chantilly
$133k-$226k/yr OnsiteFull Time
8+ YOE2+ MgmtBS in Engineering or related field; 8+ years experience; Top Secret/SCI clearance; Python; strong communication; leadership and mentoring; tool development and data analysis.
Python, Modeling and Simulation, STK, AFSIM, Model Based Systems Engineering
1w
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Lead Structural Engineer 1 - Nuclear
Englewood, Colorado, United States
$117k-$180k/yr HybridFull Time
10+ YOEBSCE; 10+ years in structural design/analysis; proficiency in STAAD, SAP2000, SAFE, STRUDL, or ANSYS; knowledge of ASCE 7, AISC, ACI; strong communication.
STAAD, SAP2000, SAFE, STRUDL, ANSYS, ASCE 7, AISC, ACI, Python, MATLAB, Excel
1mo
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Sr. Solutions Engineer, Mid- Enterprise
Boston or Denver
$118k-$178k/yr HybridFull Time
4+ YOE4+ years in Solutions Engineering, leading technical strategy in high-complexity enterprise deals; strong stack: Python, JavaScript (Node.js, React), REST, SQL; familiarity with AI tools; domain knowledge in marketing automation and CDPs.
Python, JavaScript, Node.js, React, REST, SQL
2mo
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Senior Computer Vision AI/ML Engineer (TS/SCI) {S}
Aurora, Colorado, United States
$130k-$200k/yr OnsiteFull Time
5+ YOEBS in ML/CS/CV; 5+ years exp; lead interdisciplinary team; Python ML frameworks; CV/ML model development; TS/SCI clearance; relocation benefits.
Python, PyTorch, TensorFlow, Keras, PyTorch Lightning, scikit-learn, scikit-image, OpenCV, AWS
6d
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Data Engineer - Lead
Centennial, Colorado, United States
$150k-$225k/yr OnsiteFull Time
5+ YOE5+ years in data engineering; ETL experience; data ontologies; scripting; data cataloging tools; strong communication; TS/SCI clearance
DataHub, OpenMetadata, Kibana, Grafana, Protege, Neo4j, Confluence, Jira, Python, Java, SQL, Bash, MATLAB, Excel, RESTful API, Kafka, SFTP, JMS, Data Modeling
1mo
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Principal Ground Software Developer
Broomfield, Colorado, United States
$180k-$240k/yr OnsiteFull Time
8+ YOE4+ Mgmt8-12+ years in cloud-based scalable microservice architecture; 4+ years leading developers; strong cloud and backend/frontend experience; hands-on with CI/CD and automation; able to translate customer needs into actionable items.
AWS (EKS, MSK, S3, Batch, EventBridge), Python, C++, React, Tailwind, Redis, Kafka, Influx, QuestDB, MongoDB, git, CI/CD, Docker, Kubernetes
2w
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Engineer Senior Principal – Lead Mission Analyst
Aurora or Chantilly
$133k-$226k/yr OnsiteFull Time
8+ YOE8+ years related experience; BS in Engineering or related field; TS/SCI clearance or ability to obtain; Python programming; strong communication and analytic modeling.
Python
2w
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Engineer Senior Principal – Lead Mission Analyst
Aurora or Chantilly
$133k-$226k/yr OnsiteFull Time
8+ YOEBS degree in engineering with 8+ years related experience; TS/SCI clearance with ability to obtain; Python programming; strong written and verbal communication; analytics and modeling experience.
Python, modeling and simulation, data analysis
1mo
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Space Payload RF Engineer, Lead
Chantilly or El Segundo or Aurora
$99k-$225k/yr HybridFull Time
8+ YOELead RF engineering for space payloads; 8+ years RF/microwave design; TS/SCI/Top Secret clearance; BS in Electrical Engineering; design, integration, testing; mentorship of engineers.
AWR Microwave Office, HFSS, FEKO, MATLAB, Python, GitHub, Spectrum Analyzers, Oscilloscopes, Signal Generators, EM Simulation
1mo
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Lead Observability Engineer, Global
Denver, Colorado, United States
$135k-$145k/yr RemoteFull Time
7+ YOE7+ years in observability/DevOps with Elastic Stack; strong scripting; experience with IT/OT telemetry; BI dashboards and alerting.
Elasticsearch, Logstash, Kibana, Terraform, Ansible, PowerShell, Python, Grep/Regex, Linux
2w
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Technical Lead – AI & Data Science
Denver, Colorado, United States
$98k-$155k/yr HybridFull Time
7+ YOE7+ years software engineering; 2+ years in Technical Lead/Principal role; strong GCP (Vertex AI, BigQuery, Cloud Composer, Cloud Run, GKE, Cloud Storage); Python/SQL; MLOps; GitLab CI/CD, Docker, Terraform; Bachelor’s in CS/Engineering or equivalent.
Google Cloud Platform, Vertex AI, BigQuery, Cloud Composer (Airflow), Cloud Run, GKE (Kubernetes), Cloud Storage, Python, SQL, LangChain, LLM Orchestration, MLOps, GitLab CI/CD, Docker, Terraform
2mo
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Operations Manager/Engineer (Leadership Program)
Denver, Colorado, United States
OnsiteFull Time
Lead cross-functional operations; rotate through roles; develop and own initiatives; strong communication; proficient in Python and SQL; STEM degree with high GPA.
Python, SQL, Microsoft Office
1mo
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Senior Software Algorithm Engineer
Aurora or Philadelphia
$82k-$172k/yr OnsiteFull Time
5+ YOEBS in STEM fields; 5+ years software development; lead interdisciplinary team; TS/SCI clearance; Python/C/C++, Java, or Rust; domains SDA/SATCOM/SIGINT; willing to polygraph.
Python, C/C++, Java, Rust, Linux, AWS, CUDA, OpenCV, Git, Docker, Kubernetes, S3, EC2, Lambda
13h
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Team Lead, Government-Wide Acquisition Programs
San Francisco or Lakewood or Washington or Orlando or Tampa or Atlanta or Chicago
$126k-$197k/yr OnsiteFull Time
Lead a team of Operations Research Analysts; develop reports, models, and forecasts; manage workload and provide guidance to leadership.
SQL, Excel, R, Python, SAS, Tableau
2mo
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Principal Electrical Engineer - EMI/EMC Lead
Louisville or Centennial
$164k-$226k/yr OnsiteFull Time
12+ YOESenior electrical engineer with 12+ years experience in power/control/EWIS/CD&H, strong mentoring, and leadership skills.
Capital, AutoCAD Electrical, Altium Designer, SPICE, MATLAB/Simulink, HyperLynx, PCB Design, Oscilloscopes, Multimeters, Logic Analyzers, C++, Python, CCSDS standards
1mo
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Space Payload RF Engineer, Lead
Chantilly or Aurora or El Segundo
$99k-$225k/yr OnsiteFull Time
8+ YOE8+ years RF/microwave design; space payload experience; TS/SCI clearance; BS in Electrical Engineering; leadership/mentorship experience.
AWR Microwave Office, HFSS, FEKO, MATLAB, Python, GitHub, CAMEO Enterprise Architecture
1d
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Senior Data Engineer
Denver or New York City or San Francisco
$100k-$115k/yr RemoteFull Time
3+ YOE3–5+ years of OO development (TypeScript/Java/C#/Java) with Python for data tasks; strong SQL/PostgreSQL; cloud (AWS/Azure/GCP); CI/CD; data architectures; experience with financial market data; Agile tools (Jira); Git/GitHub; ability to lead features from planning to deployment.
TypeScript, Java, CSharp, Python, PostgreSQL, SQL, AWS, Azure, GCP, Git, GitHub, Jira, Kafka, WebSockets, Medallion Architecture
1mo
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Principal GNC Engineer
Denver or Long Beach
$180k-$260k/yr OnsiteFull Time
15+ YOELead end-to-end GNC design, testing, and operations; develop flight software; perform state estimation, sensor fusion, and navigation analyses; mentor engineers.
C++, Python, GNC flight software, Star trackers, IMUs, GNSS, 6-DOF simulations, SIL/HIL, Monte Carlo, covariance analysis
HiringCafe market data
Lead Python Developer Jobs market signals in Highlands Ranch, CO, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
100+
Hiring companies
64
Fresh sample
53% new in 30d
Salary visibility
96% show pay
Companies appearing in this market
BAE SystemsCableLabsBooz Allen HamiltonDaVitaLockheed MartinSargent & LundyCACINorthrop Grumman
Work location mix in visible results
Onsite: 47Hybrid: 18Remote: 5