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Lead Python Developer Jobs in Laguna Niguel, CA, US
120+ lead python developer jobs from 72 companies hiring in Laguna Niguel, CA, US.
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Lead Software Engineer, Full Stack - Top Secret Clearance
Hawthorne, California, United States
$160k-$225k/yr OnsiteFull Time
5+ YOE1+ MgmtLead a software engineering team to design, develop, and test full stack web applications for flight systems; requires TS/JS, Python/C++, and Top Secret clearance.
React, Lit, Python, Rust, C++, Postgres, MySQL, Oracle, Bamboo, Ansible, Jenkins, Docker, Kubernetes
2mo
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Matterport - Lead Software Engineer
Irvine, California, United States
$170k-$222k/yr HybridFull Time
8+ YOE8+ years of SaaS development using Java/Kotlin; microservices with Docker/Kubernetes; relational databases; strong engineering practices.
Docker, Kubernetes, RabbitMQ, Kafka, MySQL, PostgreSQL, Java, Kotlin, Python, Elasticsearch, React, Angular, C#, .NET
1w
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Lead Simulation Engineer
Hawthorne, California, United States
$142k-$235k/yr OnsiteFull Time
10+ YOELead real-time and faster-than real-time simulations; 10+ years experience; 3+ years leading a team; integrate simulations with vehicle software; strong C++ and Python; model validation and sensor/actuator modeling.
C++, Python
1w
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Software Engineer Lead (Hybrid)
Santa Ana, California, United States
$173k-$199k/yr HybridFull Time
8+ YOE8+ years software engineering with leadership, deep database design, full-stack development, AI/ML integration, document processing, workflow design, cross-functional leadership, and cloud experience.
Python, FastAPI, React, Next.js, PostgreSQL, Docker, Kubernetes, OpenTelemetry, LangChain, Vector databases, Cloud platforms (GCP, AWS, Azure)
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Lead Machine Learning Engineer
Vancouver or Montreal or Toronto or Calgary or Ottawa or Los Angeles
$225k-$260k/yr RemoteFull Time
5+ YOEMaster’s or PhD in CS/Robotics/ML; 5+ years production ML; distributed multi-GPU training; Python; neural networks and optimization knowledge.
Python, PyTorch, TensorFlow, CUDA
2w
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Lead ETL Engineer
New York or Birmingham or Miami or Tampa or Cincinnati or Los Angeles
$140k-$199k/yr HybridFull Time
8+ YOE8+ years in data warehousing with cloud platforms, ETL tools, Python, and technical leadership.
Informatica Cloud, Azure Data Factory, SQL Packages, Python, Jenkins, GitHub Actions, AWS Redshift, CI/CD
2w
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Lead Data Engineer
Los Angeles, California, United States
$174k-$230k/yr RemoteFull Time
4+ YOE4+ years data engineering; BigQuery/dbt; Dagster/Airflow; SQL; Golang/Python; modernize data systems; strong cross-team collaboration
BigQuery, dbt, Dagster, Airflow, SQL, Golang, Python
2w
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Lead Quant Engineer
Los Angeles or New York
$195k-$225k/yr HybridFull Time
12+ YOESenior, individual contributor engineer for architecture, leadership and hands-on development of analytics platforms.
Python, Azure, Cloud, Data Platforms, Workflow Orchestration Tools
2w
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Lead Communications Systems Engineer
Hawthorne or Los Angeles
$110k-$240k/yr OnsiteFull Time
10+ YOELead a team to design and develop communications and data-link systems; strong RF, DSP, and programming skills; 10+ years experience; onsite in CA.
Python, MATLAB, C++, RF Systems, Digital Signal Processing
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Platform Engineer Lead
Irvine or New York or San Antonio
$179k-$287k/yr OnsiteFull Time
10+ YOESenior platform engineer with 10+ years; strong in SDLC, DevOps, CI/CD, AI-assisted development, and toolchain modernization.
Harness.io, SonarQube, Artifactory, Nexus, GitHub Copilot, Claude Code, Cursor, Kubernetes, Docker, Terraform, TypeScript, Python, Java, Go, OpenTelemetry, GitHub Actions
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Lead Spacecraft Test Engineer
Los Angeles, California, United States
$136k-$187k/yr OnsiteFull Time
5+ YOELead a team of spacecraft test engineers; develop and execute environmental/functional test plans; ensure compliance with aerospace standards; drive test program strategy.
LabVIEW, Python, Data Acquisition (DAQ), Instrumentation, Thermocouples, Accelerometers
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Lead Data Engineer
San Francisco or Los Angeles
$112k-$150k/yr HybridFull Time
5+ YOELead data engineer with cloud data pipelines, governance, and security; experience in Azure, Power BI, compliance (PII/PCI/HIPAA) preferred.
Azure Data Factory, Synapse Analytics, Azure Data Lake, Logic Apps, Power BI, Azure Purview, Git, Python, SQL
4w
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Software Systems Engineer (Senior/Lead)
El Segundo, California, United States
OnsiteFull Time
5+ YOESenior/Lead Software Systems Engineer with 5+ years in space/ground systems, leadership experience, Java/C++, Python, DoD Secret clearance, onsite in El Segundo, CA.
Java, C++, Python, GitLab, CI/CD, DevSecOps, Docker, Kubernetes, SQL, NoSQL, Kafka, ActiveMQ, CCSDS
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Lead Modeling and Simulation Engineer
Woburn or Boston or Arlington or Dayton or Melbourne or Carlsbad
$157k-$224k/yr HybridFull Time
5+ YOELead multi-disciplinary teams on RF sensor system modelling, with expertise in M&S frameworks, C/C++, Python, and real-time simulation.
C/C++, Python, MATLAB, Simulink
2w
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Scientific Software Developer
Pasadena, California, United States
OnsiteFull Time
4+ YOELead development and release of software for predicting spectra; strong Python/C/C++/Fortran; 4+ years in software or scientific computing.
Python, C/C++, Fortran
2w
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Lead Verification & Validation Engineer
Palo Alto or Irvine
$130k-$155k/yr OnsiteFull Time
5+ YOELead V&V strategy, mentor engineers, design/test automation, and oversee automotive software/system validation.
CAN, LIN, Ethernet, FlexRay, dSPACE, Vector VT, DBC, LDF, ARXML, HIL, MATLAB, Python, C/C++, Automotive testing tools
4w
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Lead Site Reliability Engineer
Irvine, California, United States
$136k-$177k/yr OnsiteFull Time
6+ YOE6+ years in distributed systems/SaaS; multi-region, split-plane architecture; strong SLO/MTTR focus; Python/Java/C++/JavaScript; Kubernetes, GitOps, IaC; incident management; leadership and mentoring.
Kubernetes, CI/CD, GitOps, ArgoCD, SLO/SLA design, observability, Infrastructure as Code, cloud platforms, Python, Java, C++, JavaScript, Datadog, Grafana
3w
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Lead Sr Staff Software Engineer - Front End Fundamentals
Bellevue or Boulder or Chicago or Denver or Irvine or Los Angeles or New York or San Francisco or San Jose or Seattle or Ventura
$166k-$305k/yr HybridFull Time
13+ YOE1+ MgmtSenior frontend leadership role requiring 13+ years of software development, 1+ year of people management, strong TypeScript/JavaScript or other languages, cloud and distributed systems experience, and mentoring.
TypeScript, JavaScript, C#, Java, C, C++, Python, SQL, Scala
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Lead Data Engineer – Financial Data, Compliance & Business Intelligence
Chicago or Washington or Sarasota or Hartford or Costa Mesa or San Jose or Atlanta or Boston or Cleveland or Columbus or Dallas or Fort Lauderdale or Fort Wayne or Grand Rapids or Indianapolis or Los Angeles or Miami or New York City or Oak Brook Terrace or Sacramento or San Francisco or South Bend or Tampa or Houston or Austin
$111k-$226k/yr OnsiteFull Time
3+ YOE3+ years ETL development; experience with Bank Secrecy Act/AML regulations; consulting experience; strong ETL/EDW skills; Python/Java; cloud data warehousing (Azure/AWS/Snowflake); excellent communication and teamwork.
ETL tools, Python, Java, Azure, AWS, Snowflake
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GNC Engineer Lead — Oasis-1 Mission (Space Resource Program)
Los Angeles, California, United States
$157k-$220k/yr OnsiteFull Time
Blue Origin: Develops reusable rockets and systems for human spaceflight.
5+ YOELead GNC engineer for Oasis-1 mission; 5+ years spacecraft GNC experience; proficient in EKF/UKF, C/C++, Python/Matlab; in-person role in Los Angeles.
C++, Python, MATLAB, Simulink, RTOS, Linux, Git
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DevOps Developer (Lead or Senior)
Seal Beach or El Segundo
$146k-$239k/yr OnsiteFull Time
3+ YOE3+ years in DevOps with RHEL; cloud DevOps design; scripting; IaC; travel; on-call; TS/SCI poly.
Red Hat Enterprise Linux, Terraform, Bicep, ARM, Shell scripting, Python, Perl, VMware, Jira, Confluence, PKI, Windows 10
3w
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Phantom Works Software Lead
Berkeley or Arlington or Mesa or El Segundo or Colorado Springs
$184k-$286k/yr OnsiteFull Time
5+ YOE5+ MgmtBachelor’s degree; 5+ years in leading software/architecture; Agile lead; DevSecOps and CI/CD experience; scripting (Python/Bash).
Git, Jenkins, CI/CD, Config Management, Python, Bash, JIRA, Collaborator, Beyond Compare, VersionOne
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Software Engineer, Horizontal Ops
New York City or San Francisco or Seattle or Los Angeles
$170k-$230k/yr RemoteFull Time
5+ YOE5+ years of software engineering; bachelor’s in CS or equivalent; Python, PostgreSQL/MySQL experience; ownership mindset; strong product instinct and problem solving; ability to lead and mentor.
Python, PostgreSQL, MySQL
2w
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Technical Platform Lead
Irvine, California, United States
$80k-$95k/yr HybridFull Time
5+ YOE5+ years in technical ad operations or programmatic advertising; strong DSP, SQL/BigQuery, Python; excellent communication; leadership experience.
SQL, BigQuery, Python, JavaScript, HTML
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CRM Technical Lead
Carlsbad, California, United States
$112k-$148k/yr HybridFull Time
7+ YOE7–10+ years CRM engineering experience; hands-on with major CRM platforms; strong Java and Python; AWS experience; system design and leadership.
Java, Python, AWS, DynamoDB, SQS/SNS, Lambda, API Gateway, Pub/Sub
3w
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Lead Security Engineer, Detection & Response (Data Platform)
San Francisco or Vancouver or Dallas or Dublin or Los Angeles or Houston or London or Seattle or Portland
$225k-$290k/yr RemoteFull Time
8+ YOE8-10+ years security engineering, data engineering, or detection & response; experience with large-scale data pipelines; cloud-native data services; programming in Python and SQL; experience with SIEM/SOAR; on-call responsibilities.
AWS, Kafka, Kinesis, S3, Glue, Athena, MSK, PyTHON, SQL, SIEM, SOAR
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Radar Systems Software Engineer
El Segundo, California, United States
OnsiteFull Time
8+ YOELead design, development, and validation of radar/sensor software for defense applications; requires deep radar/system knowledge and production-quality software experience.
C++, Python, Linux
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Principal AI Engineer ($211,200 - $263,800) (Irvine, CA, 92617)
Irvine, California, United States
$211k-$264k/yr OnsiteFull Time
7+ YOELead design and implementation of AI solutions using LLMs; production AI apps; client-facing; strong Python, CI/CD, MLOps, and data integration.
Python, LangChain, LLMs, CI/CD, Infrastructure as Code, Snowflake, BigQuery, Vector databases, Graph databases, Gemini, Claude, LLaMA
2mo
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Lead Data & Cloud Solutions Senior Engineer (M.S. or Ph.D.)
Los Angeles, California, United States
$138k-$169k/yr OnsiteFull Time
3+ YOEAdvanced degree (Ph.D. or M.S.) in statistics, computer science, engineering, or related field; extensive DevOps, data engineering, and cloud experience; strong communication and business development skills.
Python, R, C++, SQL, Linux, Tableau, Power BI, Docker, Kubernetes, Jenkins, Git, Terraform, Ansible, AWS, Azure, Google Cloud
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Space Payload RF Engineer, Lead
Chantilly or El Segundo or Aurora
$99k-$225k/yr HybridFull Time
8+ YOELead RF engineering for space payloads; 8+ years RF/microwave design; TS/SCI/Top Secret clearance; BS in Electrical Engineering; design, integration, testing; mentorship of engineers.
AWR Microwave Office, HFSS, FEKO, MATLAB, Python, GitHub, Spectrum Analyzers, Oscilloscopes, Signal Generators, EM Simulation
3w
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Senior Manufacturing Test Engineer
Irvine, California, United States
$110k-$135k/yr OnsiteFull Time
5+ YOELead development and validation of manufacturing test methods; 5-8+ years in manufacturing test engineering; Python; FAT/SAT; regulatory knowledge.
Python, SQL, Pandas, DAQ, PLC, Test Automation
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AI Product Engineer - Agentic AI Platforms (Financial Services)
Los Angeles, California, United States
HybridFull Time
Experience designing agentic AI platforms, leading client workshops, translating needs into product backlogs; strong Python and GenAI tooling; SDLC delivery; knowledge of LangChain, LangGraph, DSPy, and vector databases; FS domain knowledge a plus.
Python, LangChain, LangGraph, DSPy, OpenAI, Anthropic, Vector databases, Pinecone, FAISS, Milvus, Weaviate
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Senior Backend Engineer
San Francisco or Toronto or Los Angeles or Raleigh
$168k-$210k/yr HybridFull Time
5+ YOE5+ years backend or full-stack experience; 1–2+ years in senior/lead roles; Node.js with TypeScript; GraphQL/REST APIs; distributed systems; strong CS fundamentals; ability to own projects end-to-end; AI tooling experience preferred.
Node.js, TypeScript, GraphQL, REST, Docker, Kubernetes, Python
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Staff Software Engineer
Los Angeles, California, United States
$101k-$204k/yr RemoteFull Time
7+ YOEBachelor's in CS or related; 7+ years software engineering; 3+ years leading multi-team initiatives; strong Java, Spring, SQL; cloud, containers; ability to mentor.
Java, Python, Go, C++, JavaScript, REST, gRPC, Apache Kafka, Apache NiFi, Amazon SQS, MS MQ, Apache Camel, Docker, Kubernetes, AWS, Google Cloud, Azure, DevSecOps, distributed systems, microservices, SQL databases, NoSQL, caching, message queues, data streaming, APIs, cloud platforms
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Engineer Product Development (Golf Ball Testing)
Carlsbad, California, United States
$110k-$120k/yr OnsiteFull Time
5+ YOELead engineer to develop test methods, analyze data, and lead a team for golf ball testing.
Python, MATLAB, R, SQL, DOMO
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Lead Full Stack Engineer, Insights
Berlin or London or New York or Los Angeles
HybridFull Time
Architect and scale backend systems; proficient in Scala or Go; strong frontend with Next.js/React; Terraform; AI-native tooling; leadership and communication skills; cloud (GCP/AWS) experience preferred.
Scala, Golang, BigQuery, SQL, Next.js, React, Terraform, AWS ECS, Python, Airflow, GCP
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Senior Backend Software Engineer
El Segundo or Chantilly or Colorado Springs
$129k-$194k/yr OnsiteFull Time
8+ YOE8+ years in software/data architecture; strong cloud-native data-intensive software; experience leading teams; security clearance eligibility; onsite in El Segundo, CA with possible relocation.
Java, Python, Go, Kubernetes, Apache Airflow, Apache Spark, Neo4j, AWS Neptune, Palantir Warp Core, CKAD
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Advisory Lead, Software-TTS (SPAM)
Chicago or Boston or Dallas or Los Angeles or Minneapolis or New York City or San Francisco or Seattle or Washington D.C.
HybridFull Time
8+ YOE8-10+ years of hands-on software development; experience with complex systems integration, SDLC; Agile/Lean project management; ability to lead executive-facing engagements; strong communication.
C#, Java, Python, SDLC
2mo
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Senior Guidance, Navigation, and Controls Engineer (GNC)
El Segundo, California, United States
$155k-$190k/yr OnsiteFull Time
5+ YOELead end-to-end GNC development, simulate and test hardware-in-the-loop, design autonomous attitude control; strong C++/Python; aerospace systems knowledge.
C++, Python, MATLAB/Simulink, GMAT
1mo
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Space Payload RF Engineer, Lead
Chantilly or Aurora or El Segundo
$99k-$225k/yr OnsiteFull Time
8+ YOE8+ years RF/microwave design; space payload experience; TS/SCI clearance; BS in Electrical Engineering; leadership/mentorship experience.
AWR Microwave Office, HFSS, FEKO, MATLAB, Python, GitHub, CAMEO Enterprise Architecture
HiringCafe market data
Lead Python Developer Jobs market signals in Laguna Niguel, CA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
120+
Hiring companies
72
Fresh sample
43% new in 30d
Salary visibility
88% show pay
Companies appearing in this market
BoeingBlue OriginBooz Allen HamiltonCapital GroupSpaceXWhatnotSystems & Technology ResearchThe Aerospace Corporation
Work location mix in visible results
Onsite: 45Hybrid: 20Remote: 7