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Lead Python Developer Jobs in Novato, CA, US

210+ lead python developer jobs from 140+ companies hiring in Novato, CA, US.

216 jobs- Novato • 50 miles
2mo
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Lead Software Engineer
San Francisco, California, United States
RemoteFull Time
Eloquent AI
Eloquent AI: Developing autonomous AI agents for regulated financial service operations.
8+ YOE8+ years in full-stack development; leadership experience; React, TypeScript, Node.js; Python backend; cloud infrastructure (AWS, GCP, or Azure); AI/LLM familiarity; fast-paced environment.
React, TypeScript, Node.js, Python, AWS, GCP, Azure, LLMs, GraphQL, WebSockets
1mo
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Lead Software Engineer
San Francisco, California, United States
OnsiteFull Time
Clockwork Systems
Clockwork Systems: Software-driven network fabrics for GPU cluster performance optimization.
7+ YOE7+ years in software engineering or systems development; CS/EE degree; proficient in C/C++, Go, Java, Python; strong debugging; experience with large distributed systems; cloud platforms (AWS/GCP/Azure); networking; full stack.
C, C++, Go, Java, Python, AWS, GCP, Azure, Networking, Databases, Observability, Containers, Kubernetes
1mo
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Lead AI Engineer
New York or Cambridge or McLean or San Francisco or San Jose
$197k-$246k/yr HybridFull Time
Capital One
Capital OneNYSE: COF: Financial services offering credit cards, banking, and loans.
4+ YOE4+ years in AI/ML with Bachelor’s or 2+ with Master’s; strong Python/Java/Scala/Go; cloud deployment; experience with LLMs, vector databases, and guardrails.
Python, Java, Go, Scala, AWS, HuggingFace, PyTorch, VectorDBs, Nemo Guardrails, C++, C#
3mo
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CKG Lead Engineer
Pleasanton, California, United States
$150k-$220k/yr OnsiteFull Time
Avathon
Avathon: Sells industrial AI software for operational efficiency and safety.
5+ YOE5-8 years software engineering with graph tech/knowledge graphs; strong Python; experience with graph databases; knowledge of ontology and SQL, APIs; collaboration with data scientists and product teams.
Python, IQL, Neo4j, Neon/Maana, GCP, AWS Lambda, SQL, NoSQL, Time Series DBs, REST, GraphQL, TensorFlow, PyTorch, NumPy
1mo
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Lead QA Engineer
San Francisco, California, United States
$160k-$185k/yr HybridFull Time
LendingClub
LendingClubNYSE: LC: Digital marketplace bank providing personal loans and banking services.
8+ YOE8+ years of test automation experience; Bachelor's degree in Computer Science or related field (or equivalent); experience with Java, JavaScript, Python; CI/CD; API testing; SQL; distributed systems; strong communication.
Java, JavaScript, Python, SQL, REST, CI/CD, Web services, Test frameworks
1mo
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Technical Lead - Software Developer, Data Foundry
San Francisco or San Diego or Boston or Louisville or Indianapolis
$152k-$244k/yr OnsiteFull Time
Eli Lilly and Company
Eli Lilly and CompanyNYSE: LLY: Discovers, develops, and manufactures medicines for global health.
5+ YOE5–10+ years scientific software development; Python and another language; REST APIs, data pipelines, microservices; experience with scientific datasets.
Python, Java, C#, Go, TypeScript, Rust, SQL, REST APIs, Microservices, MLflow, Weights & Biases, Docker, Kubernetes, AWS, Azure, GCP, Prefect, Airflow, Nextflow, Postgres, Redshift, Snowflake, BigQuery, LIMS, ELN, Benchling, RDKit, Schrödinger, MOE, Git, Linux, Bash
1w
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Lead Software Engineer - Core AI
San Francisco or United States
$200k-$215k/yr RemoteFull Time
Zeta Global
Zeta GlobalNYSE: ZETA: Provides an AI-powered marketing platform for enterprise customer engagement.
8+ YOE8+ years engineering experience with proficiency in C#, Java, JavaScript, Go, or Python; experience with generative AI, LLMs, and cloud infrastructure; strong architecture and mentoring.
C#, Java, JavaScript, Go, Python, Generative AI, LLMs, MCP, LangGraph, OpenAI, Bedrock, Cloud infrastructure
1w
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Lead Java Software Engineer
Phoenix or San Francisco or Chicago or Denver or Salt Lake City or Madison
$85k-$160k/yr RemoteFull Time
Resource Innovations
Resource Innovations: Provides clean energy services and software solutions for utilities.
8+ YOE8+ years software development; Java/Spring Boot; cloud-based enterprise apps; strong analytical, communication, and independent working skills.
Java, Python, Spring Boot, MySQL, NoSQL, OpenSearch, Elasticsearch, Apache Camel, RabbitMQ, Data pipelines, AWS, Kubernetes, CI/CD, REST, SOAP, Microservices
4w
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Sr Lead Software Engineer - Back End
Palo Alto, California, United States
$171k-$260k/yr OnsiteFull Time
JPMorgan Chase
JPMorgan ChaseNYSE: JPM: Global financial firm providing banking and investment management services.
5+ YOE5+ years experience; strong Java/Python; Spring Boot; microservices; REST APIs; cloud and distributed systems; leadership experience
Java, Python, Spring Boot, Microservices, REST APIs, JPA, JUnit, Log4J, Kubernetes, Infrastructure as Code
1w
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Lead Data Engineer, AI
San Francisco or Chicago or Seattle or Bellevue
$173k-$260k/yr HybridFull Time
Salesforce
SalesforceNYSE: CRM: Sells cloud-based customer relationship management and business software solutions.
8+ YOE8+ years data engineering; Python, SQL; Spark; ETL/ELT tools (Airflow, dbt, Informatica); data modeling; data warehousing (SQL/NoSQL); cloud platforms (AWS/Azure/Google Cloud); Salesforce Data Cloud experience; strong cross-functional collaboration.
Python, SQL, Spark, Airflow, dbt, Informatica, AWS, Azure, Google Cloud, Data Cloud
1mo
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Senior Lead Software Engineer - Developer Infrastructure
San Francisco or Boston
$216k-$324k/yr HybridFull Time
Klaviyo
KlaviyoNYSE: KVYO: Software platform for automated e-commerce marketing and customer data.
12+ YOE12 years software development; distributed systems; Go/Python; AWS/Azure/GCP; Kubernetes; Terraform; strong leadership
Go, Python, AWS, Azure, GCP, Kubernetes, Docker, Terraform, Pants, FastAPI, Django, React, Buildkite, Apache Kafka, Apache Pulsar, RabbitMQ, Spark, Airflow, MySQL, PostgreSQL, Clickhouse, Redis, Typescript, React, Jest, Webpack, Covey
1mo
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Lead Software Engineer – AI/RAG Platform
Atlanta, Georgia, United States
HybridFull Time
Floor & Decor
Floor & DecorNYSE: FND: Specialty retailer of hard surface flooring and related accessories.
7+ YOE7–10 years of software engineering; 2–5 production RAG agents; Python backend with LLM orchestration; Angular frontend; Azure OpenAI; REST APIs; MCP integration; Agile/Scrum experience.
Python, LangChain, Semantic Kernel, Azure OpenAI, Azure AI Search, MCP, Angular, REST APIs, RAG Architecture, Google, Git
1mo
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AI Scientist Lead Engineer
San Mateo, California, United States
OnsiteFull Time
Luminary Cloud
Luminary Cloud: Cloud-native physics simulation platform for accelerated product engineering.
5+ YOEMasters or higher in CS/ME/AE or related field; 5+ years building production ML systems; experience with Physics Nemo models; CFD/FEA knowledge; Python proficiency; distributed ML a plus.
Python, Claude Code, NVIDIA Modulus, Physics Nemo, Domino, GeoTransSolver
1w
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Lead Software Engineer - Automation
Novato or Culver City
$134k-$214k/yr OnsiteFull Time
2K Vegas
2K VegasNASDAQ: TTWO: Provides quality assurance and customer support for video games.
6+ YOE6+ years software engineering; 2+ years in game engines; proficient in compiled and scripting languages; CI/CD; test automation; strong communication; interest in LLMs.
C#, C++, Go, Rust, Java, Python, Bash, TeamCity, Jenkins, GitHub Actions
2w
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Lead Applied AI / GenAI Engineer
Foster City, California, United States
$165k-$185k/yr OnsiteFull Time
Qualys
QualysNASDAQ: QLYS: Provides cloud-based platform for cybersecurity and compliance management.
7+ YOE7–12+ years in software engineering or ML, production AI/GenAI experience, Python backend, API development and data integration.
Python, APIs, SQL, Vector databases, LLMs, RAG, Cloud services
2w
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Lead Test Engineer
Fremont, California, United States
$101k-$172k/yr HybridFull Time
Coherent
CoherentNYSE: COHR: Manufactures lasers, engineered materials, and optical networking components.
10+ YOELead testing of PICs; 10+ years in photonics testing; automate tests with scripting; strong collaboration and communication.
Python, LabVIEW, Oscilloscope, Optical Spectrum Analyzer, Vector Network Analyzer, Power Meter, Probe Card
1mo
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Lead Data Engineer
San Francisco or Los Angeles
$112k-$150k/yr HybridFull Time
State Bar of California
State Bar of California: Regulates the legal profession and licenses attorneys in California.
5+ YOELead data engineer with cloud data pipelines, governance, and security; experience in Azure, Power BI, compliance (PII/PCI/HIPAA) preferred.
Azure Data Factory, Synapse Analytics, Azure Data Lake, Logic Apps, Power BI, Azure Purview, Git, Python, SQL
2w
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Lead Security Engineer
Menlo Park, California, United States
OnsiteFull Time
Periodic Labs
Periodic Labs: Builds autonomous laboratories for AI-driven scientific discovery.
Lead security engineering across cloud, Kubernetes, IAM, secrets, CI/CD, and incident response; partner with infra and lab teams to balance security and velocity.
AWS, GCP, Azure, Kubernetes, Python, Bash, Terraform, Okta, Entra, SAML, OIDC, SCIM, KMS, GitHub OIDC, CI/CD, Workload identity
4w
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Lead Software Engineer - Gov Platforms
Redwood City, California, United States
$120k-$180k/yr OnsiteFull Time
WindBorne Systems
WindBorne Systems: Operates smart weather balloons to provide global atmospheric data.
5+ YOE5+ years software engineering; full-stack across frontend and backend; data pipelines; compliance-focused security; customer-facing communication; problem solving; ability to obtain security clearance.
Ruby on Rails, PostgreSQL, Python, Rust, AWS GovCloud, Azure Government, FedRAMP, NIST 800-53
1w
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Tech Lead Manager, Developer Experience
San Francisco, California, United States
$220k-$275k/yr HybridFull Time
Peregrine
Peregrine: Data integration and analytics platform for public safety agencies.
6+ YOE2+ Mgmt6+ years software engineering; 2+ years engineering management; experience in developer tooling, CI/CD, observability, IaC; Kubernetes in production; strong Python; cloud (AWS); data-driven tooling impact; located in San Francisco and open to 4 days in office.
GitHub Actions, Jenkins, ArgoCD, Datadog, Prometheus, Grafana, Terraform, Pulumi, Kubernetes, AWS, Python, Django, Celery, Airflow, Kafka, Mapbox, PostgreSQL, Elasticsearch, Bedrock, Sagemaker
4w
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Lead GenAI Backend Platform Software Engineer
Rockville or Jersey City or Denver or San Francisco or New York City or Tysons
HybridFull Time
FINRA
FINRA: Regulates brokerage firms and exchange markets in the United States.
7+ YOE7+ years in software engineering; strong backend design; Python, FastAPI; cloud (AWS); LLMs; security; CI/CD; team leadership.
Python, FastAPI, AWS Bedrock, S3, Lambda, Step Functions, Fargate, Aurora, CI/CD, Git
1w
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Lead Automation Engineer, Director
San Francisco, California, United States
$190k-$230k/yr OnsiteFull Time
Federal Home Loan Bank of San Francisco
Federal Home Loan Bank of San Francisco: A cooperative bank providing liquidity and funding to member institutions.
7+ YOELead automation engineer with 7+ years in automation, RPA, AI, CI/CD, and team leadership; strong programming, cloud, and QA experience.
UiPath, Playwright, Power Automate, Selenium, FitNesse, GitHub Copilot, ChatGPT, Claude, TypeScript, JavaScript, Python, Java, Jenkins, GitHub Actions, Azure DevOps, Oracle, SQL Server, PostgreSQL, Amazon RDS, Jira, Confluence, Xray
1mo
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Lead Voice Infrastructure Engineer
San Francisco or New York City
$185k-$250k/yr HybridFull Time
Stuut
Stuut: Automates business accounts receivable and collections through AI agents.
Senior engineer with experience building distributed telephony systems, SIP/RTP, WebRTC, and AI-enabled voice pipelines; strong backend skills in Go/Python/C/C++.
Go, Python, C, C++, WebRTC, SIP, RTP, VoIP, DTMF, APIs, AI pipelines
3mo
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Software Engineer, AI & Developer Experience
San Francisco, California, United States
$180k-$250k/yr OnsiteFull Time
Cartesia
Cartesia: Provides real-time generative voice AI and multimodal foundation models.
2+ YOE2+ Mgmt2+ years leading software engineering teams; strong fundamentals; expert in TypeScript, Python, or Go; interest in AI-assisted development; able to build internal tools with non-technical teams.
TypeScript, Python, Go
1mo
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Lead Engineer (Data/Integrations)
San Francisco, California, United States
$200k-$250k/yr HybridFull Time
Onos Health
Onos Health: AI-powered behavioral health platform for healthcare payers.
5+ YOE5+ years data engineering with healthcare payer data; proven leadership in tech teams; hands-on integration with payer systems.
AWS, Docker, Github Actions, Terraform, Python, Django, Celery, Celery Beat, django-ninja, django-tenants, NextJS, Typescript, Tanstack Query, Shadcn UI, Zod, Nuqs, PostgreSQL, AWS RDS, S3, Clickhouse, Github, Jira, Claude Code, CoderabbitAI, Tusk
3w
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Lead Sr Staff Software Engineer - Front End Fundamentals
Bellevue or Boulder or Chicago or Denver or Irvine or Los Angeles or New York or San Francisco or San Jose or Seattle or Ventura
$166k-$305k/yr HybridFull Time
The Trade Desk
The Trade DeskNASDAQ: TTD: Cloud-based programmatic advertising platform for data-driven media buying.
13+ YOE1+ MgmtSenior frontend leadership role requiring 13+ years of software development, 1+ year of people management, strong TypeScript/JavaScript or other languages, cloud and distributed systems experience, and mentoring.
TypeScript, JavaScript, C#, Java, C, C++, Python, SQL, Scala
1mo
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Lead Data Engineer – Financial Data, Compliance & Business Intelligence
Chicago or Washington or Sarasota or Hartford or Costa Mesa or San Jose or Atlanta or Boston or Cleveland or Columbus or Dallas or Fort Lauderdale or Fort Wayne or Grand Rapids or Indianapolis or Los Angeles or Miami or New York City or Oak Brook Terrace or Sacramento or San Francisco or South Bend or Tampa or Houston or Austin
$111k-$226k/yr OnsiteFull Time
Crowe
Crowe: Global professional services firm providing audit, tax, and consulting.
3+ YOE3+ years ETL development; experience with Bank Secrecy Act/AML regulations; consulting experience; strong ETL/EDW skills; Python/Java; cloud data warehousing (Azure/AWS/Snowflake); excellent communication and teamwork.
ETL tools, Python, Java, Azure, AWS, Snowflake
2mo
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Security Engineer Lead, Corporate Security
San Francisco or New York City
$320k-$405k/yr HybridFull Time
Anthropic
Anthropic: Builds reliable and steerable artificial intelligence systems.
8+ YOE2+ Mgmt8+ years in security engineering; 2+ years leading a team; strong coding ability; deep macOS security experience; hands-on with EDR/XDR, MDM, ZTNA; SaaS security expertise.
Python, Go, SaaS security tooling, EDR/XDR, MDM, ZTNA, SSPM/CASB, DLP, CI/CD, Terraform, Cloud security tooling
2w
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Lead BI Engineer
Brooklyn or San Francisco
$180k-$210k/yr OnsiteFull Time
Altana
Altana: AI-powered visibility and risk management for global supply chains.
7+ YOE7+ years in analytics engineering/BI; SQL and dbt; dimensional modeling; lakehouse stack; KPI frameworks; strong communication.
dbt, SQL, Snowflake, BigQuery, Databricks, Looker, Tableau, Sigma, Python
1d
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Staff Software Engineer
San Mateo, California, United States
$216k-$324k/yr OnsiteFull Time
Sony Interactive Entertainment
Sony Interactive EntertainmentNYSE: SONY: Provides PlayStation gaming hardware, software, and digital network services.
8+ YOELead tool and framework development for test automation; 8+ years in C++, Python, or JavaScript with testing tools at scale.
Jenkins, GitHub Actions, ArgoCD, Python, C, C++, Rust, Git, Docker, Kubernetes
1mo
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Senior Lead Data Engineer (R4680)
San Francisco, California, United States
$140k-$210k/yr OnsiteFull Time, Temporary
Shield AI
Shield AI: Develops autonomous flight software and unmanned aircraft for defense.
7+ YOE7+ years in data engineering or cloud data architecture; SQL, Python, PySpark; production experience with Fabric, Databricks, Snowflake; data modeling; regulated environments; architectural ownership.
Python, SQL, PySpark, Microsoft Fabric, Databricks, Snowflake, Azure Data Factory, Synapse
1mo
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Senior Embedded Software Engineer
Alameda, California, United States
$114k-$228k/yr OnsiteFull Time
Abbott
AbbottNYSE: ABT: Provides medical devices, diagnostics, and science-based nutritional products.
8+ YOELead embedded software development; 8+ years in engineering; expert in C/C++/Python; embedded systems with FDA-regulated development.
C, C++, C#, Python, Embedded C, IDEs, unit testing frameworks, source control
1mo
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Tech Lead - Growth
San Francisco, California, United States
OnsiteFull Time
Arcade
Arcade: Infrastructure for AI agents to securely interact with external applications.
7+ YOE1+ Mgmt7+ years software engineering with technical leadership; strong backend and systems experience; Go/Python; React; leading small teams; growth mindset.
Go, Python, TypeScript, React, PostgreSQL
1w
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Sr. Staff AI/ML Engineer
Portland or San Francisco or Chicago or Boston or Seattle or Dallas
$220k-$256k/yr RemoteFull Time
WEX
WEXNYSE: WEX: Provides global payment processing and business information management services.
12+ YOELead development of production AI systems; 12+ years in software/ML; Python, PyTorch/TF; cloud platforms; IaC; CI/CD; Bachelor's (Master preferred).
Python, PyTorch, TensorFlow, NumPy, Pandas, scikit-learn, LangChain, ADK, AWS, Azure, GCP, Terraform, GitHub Actions
1mo
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Senior / Staff Software Engineer
Menlo Park, California, United States
$300k-$500k/yr OnsiteFull Time
Autoscience Institute
Autoscience Institute: Developing AI agents that autonomously conduct scientific research.
5+ YOELead complex engineering projects, act as technical lead, strong Python, backend and production infra, cloud experience, document design decisions.
Python, Google Cloud Platform, Backend, Distributed Systems
2w
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DevOps Lead Software Engineer
Concord or Dallas or Charlotte
$119k-$224k/yr HybridFull Time
Wells Fargo
Wells FargoNYSE: WFC: Global provider of banking, investment, and mortgage financial services.
5+ YOE5+ years software engineering; 5+ years build-deploy automation in Linux; 5+ years Gradle/Maven; 3+ years Terraform; 3+ years GCP; 3+ years Docker/Kubernetes; 3+ years CI/CD; 3+ years GitHub/Git; 3+ years UCD/Harness CD; 3+ years IaC.
Terraform, Kubernetes, Docker, GCP, Azure, Jenkins, GitHub Actions, Python, Git
2w
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Senior / Principal Software Engineer (Compiler & AI Tooling )
San Francisco, California, United States
HybridFull Time
Code Metal
Code Metal: Develops AI-powered tools for verifiable code translation.
7+ YOE7+ years in enterprise-level software development (C++ or Python); experience gathering requirements, leading large projects, and strong delivery fundamentals.
C++, Python, LLVM, Clang, MLIR, Cargo, CI/CD, PyTorch, LangChain
2mo
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Partner Engineer
Foster City, California, United States
$150k-$200k/yr HybridFull Time
Replit
Replit: AI-powered platform for building and deploying software applications.
5+ YOE5-8+ years in software engineering, partner engineering, or related roles; strong Python and JavaScript; experience with integrations and APIs; ability to lead technical strategy with partners.
Python, JavaScript, Go, REST, GraphQL, webhooks, Docker, Kubernetes, Git, CI/CD, AWS, GCP, Azure, SQL, NoSQL
2mo
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AI Engineer
San Francisco, California, United States
$200k/yr RemoteFull Time
Influur
Influur: Professional marketplace connecting digital creators with global brands.
3+ YOEDesign multi AI agent architectures, build scalable systems, integrate APIs, and lead end-to-end AI software development.
Node.js, Next.js, Python, LangChain, LLMs, RAG, REST, Docker, Kubernetes, AWS, GCP, SQL
2mo
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Staff Engineer - Technical Lead
San Francisco or United States
$120k-$150k/yr RemoteFull Time
Arine
Arine: Platform for optimizing medication therapy and improving healthcare outcomes.
10+ YOE10+ years in backend software and systems; strong Python and infrastructure expertise; leadership in technical delivery; healthcare data security and privacy awareness.
Python, AWS, Serverless, CloudFormation, CI/CD, Security best practices

HiringCafe market data

Lead Python Developer Jobs market signals in Novato, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
210+
Hiring companies
140+
Fresh sample
44% new in 30d
Salary visibility
84% show pay

Companies appearing in this market

AnthropicCapital OneJPMorgan ChaseSalesforceAbbottAltanaCoherentEli Lilly

Work location mix in visible results

Hybrid: 28Onsite: 28Remote: 6

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