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Lead Python Developer Jobs in Ohio, United States

410+ lead python developer jobs from 230+ companies hiring in Ohio, United States.

All jobs in Ohio, United StatesLead Python Developer Jobs in United States
Cities:Columbus·Cleveland·Cincinnati·Toledo·Akron·Dayton·Parma·Canton·Youngstown·Lorain·Hamilton·Springfield·Kettering·Elyria·Lakewood·Cuyahoga Falls·Middletown·Newark·Euclid·Mentor
410 jobs- Ohio
1mo
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Java / Python Lead Software Engineer- Trading Systems
Columbus, Ohio, United States
OnsiteFull Time
JPMorgan Chase
JPMorgan ChaseNYSE: JPM: Global financial services firm providing banking and investment solutions.
5+ YOE5+ years with Java or Python; experience with Java, Microservices, Spring Boot, React; cloud native, CI/CD, agile methods; able to lead and mentor developers.
Java, Python, React, Spring Boot, Microservices, CI/CD, Cloud, Automation
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1mo
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Lead Software Engineer - Python/AWS
Columbus, Ohio, United States
OnsiteFull Time
JPMorgan Chase
JPMorgan ChaseNYSE: JPM: Global financial firm providing banking and investment management services.
5+ YOE5+ years of software engineering experience; expertise in Java, Python, AWS, SQL, and data technologies; SDLC in Agile; strong architecture and design skills.
Java, Python, AWS, Spark, Snowflake, ETL, SQL, Data Warehousing, PySpark
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1w
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Senior Confluent Kafka Lead / Python Developer (Nashville, TN, US)
Nashville or Columbus
$82k-$193k/yr OnsiteFull Time
Capgemini
CapgeminiEuronext Paris: CAP: Provides global IT consulting and digital transformation services.
6+ YOE6–10+ years software/data engineering; 4+ years with Apache Kafka/Confluent; strong Python; cloud/hybrid deployments; CI/CD; IaC; Kafka security and governance.
Apache Kafka, Confluent Platform, Python, Kafka Connect, ksqlDB, Terraform, CloudFormation, ARM/Bicep, Docker, Kubernetes, GitHub Actions, Jenkins, GitLab, Azure DevOps, Prometheus, Grafana, Confluent Control Center
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1w
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Technical Lead, Python Backend Engineer
United States
$85-$95/hr RemoteContract
3Pillar Global
3Pillar Global: Develops custom software products and digital solutions for companies.
6+ YOE2+ MgmtLead backend architecture and delivery of Python services on AWS; mentor team; ensure secure, scalable cloud-native systems.
Python, Javascript, SQL, REST API, OAuth 2, Docker, PostgreSQL, AWS, Kubernetes, EKS, Lambda, API Gateway, Jira, Bitbucket, GitHub, Slack, Teams, Pyramid, VSCode, Typescript, Snowflake, SQLAlchemy
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6d
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Software Engineer Lead - AML Tech
Pittsburgh or Strongsville or Birmingham or Dallas
$55k-$179k/yr OnsiteFull Time
PNC Financial Services
PNC Financial ServicesNYSE: PNC: Provides banking, lending, and investment services to customers.
3+ YOELead design and development of software; Spark3, Python, Hadoop; data modeling with Erwin/Alation.
Apache Spark, Python, Shell Scripting, Hadoop, Cloudera, Erwin, Alation
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4d
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Lead GenAI Cloud Developer
United States
$94k-$149k/yr RemoteFull Time
Elastic
ElasticNYSE: ESTC: Software platform for search, security, and observability.
5+ YOELead GenAI cloud developer for ElasticGPT; advanced agentic capabilities; Python/TypeScript; Elasticsearch; Kubernetes; cloud infra; GenAI systems.
Python, TypeScript, PyTorch, TensorFlow, Hugging Face, Elasticsearch, Kubernetes, Docker, LangGraph, LangSmith, n8n, OpenTelemetry, OpenAI, Anthropic, Vertex AI, BM25, vector search, Confluence, Jira, GitHub, ServiceNow
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1w
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Lead Developer
United States
$111k-$211k/yr RemoteFull Time
Kyndryl
KyndrylNYSE: KD: Designs and manages mission-critical information technology systems.
7+ YOE7+ years software engineering experience; strong Java, Python, .NET; microservices, containers (Docker, Kubernetes); relational and NoSQL databases; REST/JSON; architectural design and CI/CD.
Java, Python, .NET, Docker, Kubernetes, REST, XML, JSON, CI/CD
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4w
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Lead Developer – Security Application Development (Back-End)
Cincinnati, Ohio, United States
$78k-$113k/yr OnsiteFull Time
CBTS
CBTS: Provides managed IT, cloud, security, and communications infrastructure services.
8+ YOELead Backend developer with cloud security automation; proficient in Java/Spring Boot, Node.js, or .NET; REST APIs, CI/CD, Python for scripting, SIEM/EDR, cloud platforms.
Java, Spring Boot, Node.js, C#/.NET, REST, SQL, MS SQL, Azure, AWS, GCP, CI/CD, Git, Maven, Docker, Python, SOAR, Cortex XSOAR, Microsoft Sentinel, Dropzone AI, EDR, SIEM
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2mo
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Lead Tools Engineer (Build & Infrastructure)
Timonium or United States
$128k-$156k/yr RemoteFull Time
Xsolla: Provides payment and monetization tools for video game developers.
5+ YOELeads design and development of internal tools for game development, build pipelines, and CI/CD; 5+ years in software engineering and tooling, strong C#/Python, Linux, and CI/CD experience.
C#, Python, Bash, Unity, AWS CDK, CloudFormation, Git, Linux
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1mo
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Lead Software Engineer
United States
$165k-$175k/yr RemoteFull Time
Walker & Dunlop
Walker & DunlopNYSE: WD: Provides commercial real estate lending and advisory services.
10+ YOE10+ years of software development; API design; OpenAPI; AWS; Docker/Kubernetes; Python; real estate or financial services experience preferred.
Python, FastAPI, Vue.js, PostgreSQL, Redis, Docker, Kubernetes, AWS, Mapbox, OpenAPI
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4w
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Lead Developer, Sales Capabilities & Information Services
Orrville or Akron
HybridFull Time
The J.M. Smucker Co.: Produces and markets consumer food, coffee, and pet products.
5+ YOE5+ years of development experience across multiple technologies; strong AWS (CloudFormation/Lambda), Python, GitHub Actions, and T-SQL; Salesforce APEX/LWC; full SDLC; Agile/Waterfall/DevOps; strong integration and data skills; mentoring and presentation abilities.
AWS CloudFormation, AWS Lambda, Python, GitHub Actions, T-SQL, Salesforce APEX, Lightning Web Components
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5d
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Lead Java Software Engineer
Salt Lake City or United States
$85k-$160k/yr RemoteFull Time
Resource Innovations
Resource Innovations: Provides clean energy services and software solutions for utilities.
8+ YOEBachelor’s or Master’s in CS/Engineering; 8+ years in software development; strong Java, Python, Spring Boot; cloud, microservices; AWS; CI/CD; Kubernetes.
Java, Python, Spring Boot, MySQL, NoSQL, OpenSearch, Elasticsearch, APM, Apache Camel, RabbitMQ, Data pipelines, AWS, CI/CD, Kubernetes, Microservices
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4w
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Lead Software Engineer
United States
RemoteFull Time
OfficeSpace
OfficeSpace: AI-powered platform for workplace management and space planning
7+ YOE7+ years building production web apps; backend in Python/Ruby on Rails; frontend in React; scalable, secure AI-enabled systems.
Python, Ruby on Rails, React, GCP, BigQuery, Kafka
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2w
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Lead Software Engineer
United States
$155k-$195k/yr RemoteFull Time
Qventus
Qventus: Automates hospital operations using AI-driven software and predictive analytics.
6+ YOESenior software engineer with 6+ years’ Python experience; technical leadership; design, deployment, and scaling in microservices; strong cross-functional collaboration.
Python, Typescript, React, Databricks, Kafka, Domain Driven Design
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2mo
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Lead Software Engineer
United States
$144k-$170k/yr RemoteFull Time
Allegion
AllegionNYSE: ALLE: Provides mechanical and electronic security hardware and access systems.
8+ YOE8+ years software engineering; BS/MS in CS; strong in C#/Java/Python; Azure; CI/CD; DevOps; production support experience.
CSharp, DOTNET, Java, Python, Azure, CI/CD, DevOps, Automated Testing
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1w
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Lead AI Engineer
United States
RemoteFull Time
Legrand
LegrandEuronext Paris: LR: Manufacturer of electrical and digital building infrastructure solutions.
6+ YOESenior AI/ML engineer leading enterprise AI solutions; architecture, deployment, leadership.
Python, FastAPI, Azure, CosmosDB, Container Registry, Azure AI Search, Key Vault, Azure networking, React, Node.js, LangChain, LangGraph
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2mo
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Senior Lead Software Engineer
United States
$130k/yr RemoteFull Time
NAVEX
NAVEX: Provides an integrated platform for governance, risk, and compliance management.
6+ YOE2+ Mgmt6+ years of software development and 2+ years in leadership; strong OO design, Agile, CI/CD; Python/SQL stack; cloud/data tooling; GitHub practices.
Python, SQL, PostgreSQL, Aurora, Pandas, NumPy, Snowflake, Databricks, Docker, Airflow, GitHub
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1mo
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Lead AI software Engineer
Columbus, Ohio, United States
$119k-$187k/yr OnsiteFull Time
Wells Fargo
Wells FargoNYSE: WFC: Global provider of banking, investment, and mortgage financial services.
5+ YOE2+ Mgmt5+ years software engineering; 4+ years Python; 2+ years AI tools/automation; 2+ years technical lead; 2+ years cloud/kubernetes experience
Python, GCP, Azure, Kubernetes, OpenShift, React, JavaScript, MongoDB, Neo4j
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1mo
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Lead AI Engineer
United States
$95k-$170k/yr RemoteFull Time
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital: Pediatric research hospital treating children with catastrophic diseases.
5+ YOELead design and deployment of production-grade AI/ML systems for healthcare; ensure reliability, governance, and collaboration with stakeholders.
Python, PyTorch, TensorFlow, MLOps, NLP, LLMs, RAG, Azure, Epic EHR, Cogito, Nebula
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2mo
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Lead LLM Engineer
United States
RemoteFull Time
Renfroe
Renfroe: Provides insurance claims management and catastrophe response services.
6+ YOELead Azure-based LLM stack design, fine-tuning, and deployment; build retrieval pipelines; optimize performance and reliability.
Azure Machine Learning, AKS, FAISS, Pinecone, Python, Go, Java, Docker, Kubernetes, FastAPI, Flask, Azure AD, Key Vault, Azure Monitor, Grafana, LoRA, QLoRA, PEFT
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1mo
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AI Enabled Lead Engineer
United States
RemoteFull Time
Stride
Stride: Provides custom software development and agile consulting services.
6+ YOE6+ years of full-stack/software engineering; backend APIs in Java/Python/Ruby; frontend in React/NextJS; relational and NoSQL DBs; REST, distributed systems; TDD and pair programming; Agile; client-facing; familiarity with AI tooling and LLM integration.
Java, Python, Ruby, React, NextJS, LangChain, LangGraph, CrewAI, AutoGen, LLM APIs, REST, SQL, NoSQL
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4w
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Lead Software Engineer
Dayton or Arlington or Woburn or United States
$157k-$224k/yr HybridFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
2+ YOELead software engineer with 2-7+ years, strong C/C++, real-time embedded systems, Linux, open architecture, and security clearances.
C/C++, MATLAB, Python, Linux, OpenCL, CUDA, Git, CI/CD, DevOps
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22h
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Lead AI/ML Engineer, epocrates
United States
$148k-$252k/yr RemoteFull Time
athenahealth
athenahealth: Cloud-based software for medical practice management and electronic records.
5+ YOELead NLUP engineer with ML/AI expertise in healthcare; strong Python, DL frameworks, LLMs, and cloud experience; mentoring and cross-functional collaboration.
Python, PyTorch, TensorFlow, Transformers, GPT, RAG, SQL, PostgreSQL, AWS, Linux, Unix, Knowledge Graph, Kafka, Apache Spark, Docker, Kubernetes
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1d
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Lead Software Engineer
United States
$220k-$240k/yr RemoteFull Time
Twin Health
Twin Health: Improving metabolic health through personalized AI digital twin technology
6+ YOE6+ years of software engineering (backend or full-stack); strong Python and/or Java; experience with FastAPI and Spring Boot; API design, event-driven systems, and distributed architectures; AI-related experience; leadership; AWS, Kubernetes, and CI/CD familiarity; remote US work eligibility.
Python, Java, FastAPI, Spring Boot, REST, OAuth2, JWT, AWS, Kubernetes, CI/CD
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2mo
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Lead Software Engineer, Security
United States
$170k-$248k/yr RemoteFull Time
SeatGeek
SeatGeek: Marketplace for buying and selling live event tickets
5+ YOE5+ years in security engineering; proficient in Python, Go, C#; strong software engineering; leadership across security projects
Datadog, AWS, GitLab, Kubernetes, Hex, Looker, Redshift, CrowdStrike, C#, Go, Python, SQL, Terraform
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2w
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Lead Software Engineer - Remote
Minneapolis or United States
$113k-$193k/yr RemoteFull Time
UnitedHealth Group
UnitedHealth GroupNYSE: UNH: Provides health insurance and technology-enabled health care services.
7+ YOE3+ MgmtLead software engineer with 7+ years in SDLC/SRE/DevOps; 3+ years leading teams; strong observability, AI/GenAI, cloud (Azure); Java full stack, Kafka, React, Node.js; automation and security focus.
Java, Full Stack, Kafka, React, Node.js, Azure, Open Telemetry, Splunk, Grafana, Prometheus, Python, Bash, PowerShell, Terraform, ARM/Bicep, Ansible
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1mo
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Lead Data Engineer (Hypergiant)
United States
$137k-$180k/yr RemoteFull Time
Accelint
Accelint: Provides AI-driven autonomous systems for national security missions.
10+ YOE10+ years software/data engineering; strong Python and TypeScript; databases and messaging; data fabric with Kafka; Docker/Kubernetes; Git/CI/CD; data modeling; US citizen with security clearance.
Python, TypeScript, Java, Bash, PostgreSQL, PostGIS, RabbitMQ, Apache NiFi, Apache Pulsar, Apache Kafka, Docker, Kubernetes, Git, Jenkins, Ansible, Terraform, JSON, GeoJSON, XML, YAML
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3w
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Lead Software Engineer - REMOTE
Cincinnati, Ohio, United States
$150k-$175k/yr RemoteFull Time
Reflect Health
Reflect Health: Provides administrative services and technology for self-funded health plans.
Proven experience designing, building, and launching production systems with backend and frontend expertise; stack includes C#/.NET, SQL, Python; frontend React/Next.js; cloud-native architectures (AWS/Azure); mentorship and leadership in fast-moving environments.
C#, .NET, SQL, PostgreSQL, Python, React, Next.js, AWS, Azure
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2mo
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Lead Field Engineer
United States
RemoteFull Time
TurbineOne
TurbineOne: Provides edge-based artificial intelligence for military threat recognition.
Lead field integration, tooling development, and deployment of FPS with travel. Must be eligible to obtain U.S. government clearance.
JavaScript, Python, Go, Bash, FPS deployment tooling, deployment automation
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1mo
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Lead Analytics Developer
Dayton, Ohio, United States
HybridFull Time
Credence
Credence: Provides technology and management solutions to federal government agencies.
7+ YOE7+ years in BI/analytics, data engineering, or database development; strong SQL, data modeling; ETL/ELT; cloud data warehouses; Python/R/Java; ML; security and QA; DoD/regulatory experience; Secret clearance; BI/Cloud certifications.
Looker, Looker Studio, BigQuery, Power BI, Tableau, Qlik, SQL, Python, R, Java, Dataform
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2mo
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Lead Software Development Engineer
United States
$170k-$189k/yr RemoteFull Time
Shipium
Shipium: Enterprise platform optimizing e-commerce shipping costs and delivery speed.
5+ YOEBachelor’s degree or 5–8 years in platform engineering, distributed systems, or software development; 3+ years designing scalable cloud-native services; AWS, microservices; AI coding tools; mentoring.
Java, Python, TypeScript, AWS, Docker, Kubernetes, PostgreSQL, MongoDB, Redis, Claude Code
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1mo
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Lead Data Engineer
United States
$87k-$102k/yr RemoteFull Time
Cushman & Wakefield
Cushman & WakefieldNYSE: CWK: Global commercial real estate and property services firm.
6+ YOE3+ MgmtLead architect and develop enterprise-scale data platforms; strong Databricks/Delta Lake in Azure; leadership and mentoring responsibilities.
Databricks, Delta Lake, Azure, Unity Catalog, Spark, SQL, Python, PySpark, Scala, R, CI/CD, Git, Terraform, Infrastructure as Code
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1w
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Lead Software Engineer - Core AI
San Francisco or United States
$200k-$215k/yr RemoteFull Time
Zeta Global
Zeta GlobalNYSE: ZETA: Provides an AI-powered marketing platform for enterprise customer engagement.
8+ YOE8+ years engineering experience with proficiency in C#, Java, JavaScript, Go, or Python; experience with generative AI, LLMs, and cloud infrastructure; strong architecture and mentoring.
C#, Java, JavaScript, Go, Python, Generative AI, LLMs, MCP, LangGraph, OpenAI, Bedrock, Cloud infrastructure
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2w
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Lead GCP Engineer: AI Platforms & Development
United States
$122k-$192k/yr RemoteFull Time
Concentrix
ConcentrixNasdaq: CNXC: Global provider of customer experience solutions and outsourcing services.
8+ YOE8+ years backend software engineering; 3+ years on Google Cloud Platform; expert in Python and/or Go; experience with Gemini, Vertex AI SDKs, ADK, and CI/CD.
Python, Go, Vertex AI, Gemini, ADK, Terraform, BigQuery, Vertex AI SDK, Cloud Run, GKE, Cloud Functions
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1mo
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Lead Machine Learning Engineer
United States
RemoteFull Time
Janea Systems
Janea Systems: Develops high-impact software and AI solutions for enterprise clients.
8+ YOE8+ years software/ML experience; 3+ years leadership; production ML deployment; PyTorch/TensorFlow; Python; cloud; containers; MLOps; strong English; CS/ML degree.
PyTorch, TensorFlow, Python, Docker, Kubernetes, AWS, Azure, GCP, MLops, Feature Stores, Model Monitoring
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3w
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Lead Information Security Software Engineer (ISE)
United States or Ohio
$82k-$173k/yr RemoteFull Time
Fifth Third Bank
Fifth Third BankNASDAQ: FITB: Provides retail, commercial, and wealth management financial services.
4+ YOELead role developing API-driven security tools; expert in multiple languages; cloud and security tooling experience.
Python, JavaScript, Java, C/C++, C#, Go, API, Vue.js, Angular, React, FastAPI, Django, AWS, Splunk, Elasticsearch, EDR, SIEM, SOAR, XDR
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2mo
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Test Automation Engineer Lead
United States
$129k-$215k/yr RemoteFull Time
Symetra
Symetra: Provides life insurance, annuities, and employee benefit solutions.
8+ YOE3+ MgmtLead a small automation team; design and implement scalable test automation frameworks; hands-on leadership with CI/CD focus.
Python, Selenium, Cypress, Playwright, Postman, CI/CD, AWS, Azure, GCP, GitHub Actions, Azure DevOps
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3w
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Lead AI Engineer
United States
$99k-$207k/yr RemoteFull Time
CACI
CACINYSE: CACI: Provides information technology and professional services to government clients.
7+ YOE7 years of software development with 2-5 years in NLP/ML, strong Python/JavaScript/Rust, experience with RAG, LLMs, NLP, REST APIs, cloud services, vector databases, and agile teams.
LangGraph, CrewAI, Langfuse, LangSmith, Docker, Git, REST APIs, AWS, OCI, Vector databases, NLP, Python, JavaScript, Rust, Go
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1w
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Lead Data Engineer
United States
$142k-$196k/yr RemoteFull Time
Humana
HumanaNYSE: HUM: Provides health insurance plans and clinical healthcare services.
5+ YOE5+ years data engineering experience; at least 2 years in a lead/senior role; expert in Databricks, Spark, Unity Catalog, Delta Lake; Python; Kafka; CI/CD; REST APIs; strong communication and leadership.
Databricks, Apache Spark, Unity Catalog, Delta Lake, Python, Kafka, GitHub, REST APIs, CI/CD
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3w
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Lead AI Engineer
Chicago or United States
$160k-$180k/yr RemoteFull Time
When
When: AI platform for health insurance and employee offboarding transitions.
5+ YOE5+ years software engineering; 2–3 years AI/ML in production; LLM orchestration; data pipelines; observability; cloud infra; strong communication and business sense.
LangChain, LangGraph, Prompt Engineering, LLM platforms, GCP, AWS, Azure, Vertex AI, Claude, Cursor, GitHub Copilot, Python, TypeScript, GraphQL
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HiringCafe market data

Lead Python Developer Jobs market signals in Ohio, United States

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
410+
Hiring companies
230+
Fresh sample
55% new in 30d
Salary visibility
72% show pay

Companies appearing in this market

JPMorgan ChasePNC Financial ServicesSystems & Technology ResearchUnitedHealth GroupZeta GlobalAccelintathenahealthElastic

Work location mix in visible results

Remote: 41Onsite: 16Hybrid: 7

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