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Python Developer Jobs in Lowell, MA, US
2,100+ python developer jobs from 540+ companies hiring in Lowell, MA, US.
3w
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Principal Software Engineer
Nashua, New Hampshire, United States
$116k-$197k/yr OnsiteFull Time
4+ YOEBachelor's in CS/EE, 4+ years Python, backend microservices, modular architecture, automated testing, and DevSecOps experience.
Python, Git, Kubernetes, Pytest, Unittest, Docker
3w
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Staff Software Engineer
Waltham, Massachusetts, United States
$134k-$168k/yr OnsiteFull Time
4+ YOE4+ years real-time Linux OS development; strong Linux kernel knowledge; C/C++, Golang, Python; IPC/concurrency; Jira/Git; BS/MS in CS/CE or equivalent
Jira, Git, GitHub, Linux
1w
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Rust Software Developer
McLean or Chantilly or Beavercreek or Huntsville or Redstone Arsenal or Annapolis Junction or El Segundo or Rome or Aurora or Colorado Springs or Lexington
$87k-$198k/yr RemoteFull Time
3+ YOE3+ years in Rust software development; Kubernetes architecture; CI/CD; cloud scaling; security clearance (Secret); BS in CS/Engineering or 7+ years experience in lieu of degree.
Kubernetes, GitHub Actions, GitLab CI, Jenkins, PyO3, Rust, Python, cargo
2mo
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1.10 Software Engineer, Human-Robot Interaction
Boston, Massachusetts, United States
OnsiteFull Time
Bachelor's in CS/Robotics/Related field; hands-on HRI system development; Python and C++ proficiency; experience with foundation models and production software; strong collaboration and communication.
Python, C++, Foundation Models
2mo
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Front Office Quantitative Developer
Boston, Massachusetts, United States
$160k-$190k/yr HybridFull Time
3+ YOE3+ years programming; strong Python; cloud experience; Snowflake; Prompt Flow; Azure; DevOps; Bachelors in CS/Engineering preferred.
Python, Snowflake, Prompt Flow, Azure, DevOps, SQL, CI/CD
6d
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Senior AI Engineer
Boston or Los Angeles
$143k-$215k/yr RemoteFull Time
5+ YOE5+ years in production software; 2+ years with LLM-based apps; Python production experience; LangChain/DeepAgent or similar; API integrations; multi-agent systems; strong prompt engineering
Python, LangChain, DeepAgent, LangGraph, CrewAI, AutoGen, API integrations, Celery, RQ, Temporal, Weaviate, Pinecone, pgvector, CLAUDE, Cursor, Copilot, LLM APIs
4w
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AI Software Engineer (GenAI/RAG/Azure AI Foundry)
Boston, Massachusetts, United States
HybridFull Time
Experience with GenAI, Retrieval-Augmented Generation (RAG), Azure AI Foundry, Python, backend/full-stack development, and deploying AI solutions on Azure; familiarity with Docker/Kubernetes; SQL/NoSQL.
Python, FastAPI, Docker, Kubernetes, Azure, Azure Kubernetes Service, Azure AI Foundry, Azure OpenAI, Azure ML, SQL, NoSQL, Angular, Spring Boot, Node.js
2w
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Senior Engineer - Generative AI
Niskayuna or Cambridge
$113k-$189k/yr HybridFull Time
5+ YOE5+ years experience; Master’s or PhD in CS/AI/ML; 3+ years prompt engineering; Python and ML tooling; strong communication.
Python, PyTorch, OpenAI GPT, Hugging Face, Pandas, NumPy
1d
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Mid-Level Software Engineer
Fairfax or Lexington
$90k-$180k/yr OnsiteFull Time
8+ YOESecret clearance; 8-10 years software Eng; ML/AI with Python/Java/C++; ML libraries; cloud; Agile; Git.
Python, Java, C++, TensorFlow, PyTorch, Scikit-learn, Git, AWS, Azure
3w
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Senior Software Engineer
Boston or Somerville
$129k-$194k/yr RemoteFull Time
5+ YOEStrong Python, distributed systems, cloud (AWS/GCP/Azure); experience with LLMs, AI agents; senior individual contributor.
Python, AWS, GCP, Azure, Jira, Git, LLMs, RAG, APIs
1mo
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AI Engineer II
Boston, Massachusetts, United States
$116k-$174k/yr HybridFull Time
3+ YOE3+ years software engineering; Python and web stack; cloud experience; AI tooling exposure; mentorship and leadership experience
Python, FastAPI, Django, MySQL, PostgreSQL, AWS
9h
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Solutions Engineer
New York City or Atlanta or Chicago or Austin or Boston or Minneapolis
$95k-$160k/yr HybridFull Time
4+ YOE4+ years in a technical, customer-facing role for enterprise SaaS; manufacturing/OT exposure; Python/SQL; REST APIs; Bash; Linux/Windows; strong communication; travel 25–40%; US driver’s license; based in NYC metro, Atlanta, Chicago, Austin, Boston, or Minneapolis.
Python, SQL, REST APIs, Bash, Linux, Windows
4d
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Scientific Software Developer - Affinity
Santa Fe or Boston
HybridFull Time
3+ YOEPhD with postdoc in structure-based ligand design; 3+ years in Python; 3+ years in Molecular Dynamics and Free Energy Calculations; team-oriented with strong communication; ability to learn new methods.
Python, C++, Molecular Dynamics, Free Energy Calculations, Computational Chemistry
4d
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Software Engineer, Senior
McLean or Annapolis Junction or Aurora or Beavercreek or Chantilly or Colorado Springs or El Segundo or Huntsville or Lexington or Redstone Arsenal or Rome
$87k-$198k/yr HybridFull Time
7+ YOE7+ years of software engineering; Rust/C/C++/Python; full-stack; Kubernetes; CI/CD; security; TS/SCI or Secret clearance; BS in CS or Engineering or 5+ years exp.
Rust, C, C++, Python, Kubernetes, CI/CD, Code copilots, Static analysis tools
1mo
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Senior AI Engineer
Atlanta or Boston or Charlotte or Chicago or Dallas or Los Angeles or New York or San Francisco
$145k-$230k/yr HybridFull Time
3+ YOE3–8+ years software engineering experience with AI/ML systems; production LLM apps (RAG, agentic workflows); Python; LangChain/LangGraph/AutoGen/DSPy; strong data engineering basics.
Python, LangChain, LangGraph, AutoGen, DSPy, SQL, NoSQL, Vector databases, ETL
4d
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AI Staff Engineer (SW Engineer IV+)
Philadelphia or Boston or New York City or Baltimore or Washington D.C. or Charlotte or Raleigh-Durham or Atlanta or Chicago
$170k-$220k/yr HybridFull Time
8+ YOE8+ years software engineering; experience with Python/JS/TS; data pipelines; AI/ML production; cloud-native systems (AWS); strong cross-functional collaboration.
Python, JavaScript/TypeScript, AWS, Databricks, Spark, Snowflake, AI/ML
1w
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Software Engineer - Client Systems
Boston, Massachusetts, United States
$115k-$165k/yr HybridFull Time
6+ YOE6-8 years in C#/.NET, Python, SQL; Angular; cloud platforms (Azure/AWS); OO design; distributed systems; Agile practices.
C#, .NET, Angular, Python, SQL, Azure, AWS
1w
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Knowledge Graph Engineer
Reston or Somerville
$140k-$170k/yr HybridFull Time
2+ YOE2–5 years software engineering; Python and at least one typed language; graph databases; SQL; cross‑team collaboration
Python, Java, Go, TypeScript, ArangoDB, Neo4j, TigerGraph, JanusGraph, NetworkX, SQL, BigQuery, Cloud Run, GCP
1w
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Senior Software Engineer
Quincy or Cranston
$139k-$181k/yr OnsiteFull Time
6+ YOEBachelor’s in software engineering or computer science with 8+ years (or Master’s with 6+); C/C++, Python; Linux; embedded; Agile; DoD clearance.
C/C++, Python, Linux, Matlab, Eclipse, VS Code, Git, Jira, SVN, Shell, Office, Visio
1mo
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Sr. Software Systems Engineer
Mounds View or Newton
$119k-$179k/yr OnsiteFull Time
4+ YOEBachelor's degree plus 4+ years of relevant experience or Master’s with 2+ years or PhD with 0+ years; MBSE/SysML knowledge; software development experience; MBSE, SysML, Python/C/C++, QT/QML; Git; Agile; strong communication; ability to work in fast-paced team.
SysML, Python, C++, C#, QT/QML, Git, Agile
1w
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Software Engineer (Forward Deployed)
Boston or United States
$100k-$120k/yr RemoteFull Time
1+ YOEBachelor's in CS/Engineering; 1-3 years in a technical role; Python (required); cloud tech experience; familiarity with LLMs and prompt engineering; strong communication and teamwork.
Python, Git, Google Cloud Platform, APIs, Databases, LLMs, Prompt engineering
2mo
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Software Engineer | Government
Boston or New York City
$180k-$235k/yr OnsiteFull Time
5+ YOE5+ years in production systems; BS in CS/CE/EE/Robotics or equivalent; proficiency in Java, C++, Python, JavaScript; cloud experience (GCP/AWS/Azure); API design; strong communication; travel to other offices occasionally.
Python, TypeScript, React, Google Cloud, Java, C++, JavaScript
3mo
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Senior Backend Software Engineer
San Francisco or Boston or Denver or New York
$160k-$207k/yr HybridFull Time
3+ YOEBackend engineering with experience in distributed systems, databases, and APIs. Familiarity with Python, SQLAlchemy, and cloud deployments preferred.
Typescript, Python, Flask, SQLAlchemy, Kubernetes, AWS, React
1mo
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Senior Engineer 2: Inference Data Plane
Boston, Massachusetts, United States
$167k-$209k/yr RemoteFull Time
Senior engineer with distributed systems experience in AI inference, Go/Python, and cloud-scale services.
Go, Python, gRPC, Docker, Kubernetes, Vercel
1mo
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Machine Learning Engineer
Boston or United States
$130k-$185k/yr RemoteFull Time
Experience building ML models for real-time data; strong Python/C++; ML libraries; sensor/wearable data; self-directed; growth mindset.
Python, C++, TensorFlow, PyTorch, Pandas, NumPy
2w
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Machine Learning Engineer
Manchester, New Hampshire, United States
OnsiteFull Time
6+ YOEMS in CS or AI; 6+ years backend and distributed systems; strong Java/Python; production ML models; Kafka/Spark; microservices; databases; AWS.
Java, Python, Spring Framework, Hibernate, PyTorch, Kafka, Spark, ZooKeeper, AWS, REST APIs, NoSQL databases, SQL databases
5d
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Software Engineer I/II, Machine Learning
Boston, Massachusetts, United States
$130k-$190k/yr HybridFull Time
5+ YOE5-8+ years, strong Python, ML lifecycle, GPU deployment, cloud, cross-functional collaboration.
Python, PyTorch, Hugging Face, vLLM, Triton, ONNX Runtime, Pandas, Arrow, S3, Parquet, Prefect, Airflow, Luigi, AWS, Docker, Kubernetes
1w
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Staff Software Engineer - Applied AI
Boston, Massachusetts, United States
$175k-$250k/yr RemoteFull Time
Bachelor’s or Master’s in CS/Engineering; backend engineer with Python (Ruby/Go a plus); design scalable APIs; cloud and AI ecosystem knowledge.
Python, Ruby, Go, AWS, Snowflake, OpenAI, Claude, Hugging Face, Langchain
1mo
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Firmware Engineer lll
Woburn, Massachusetts, United States
OnsiteFull Time
6+ YOEBachelors in Electrical Engineering, Computer Science, or related field; 6+ years firmware/embedded software; US person; experience with C/C++, ARM Cortex-M, microcontrollers; OS-less devices; schematic/PCB reading; debugging with SWD/JTAG; Git; Python.
C, C++, ARM Cortex-M, Microcontrollers, Python, Git, GitHub, FreeRTOS, lwIP, MQTT, Azure, I2C, SPI, DMA, JTAG, SWD, Altium, LTSPICE, Linux
3w
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Senior Edge Infrastructure Engineer
Somerville, Massachusetts, United States
$140k-$200k/yr HybridFull Time
5+ YOE5+ years as a strong software/hardware engineer; edge deployment experience; Linux/NixOS; Python; US work authorization.
NixOS, Linux, Python, Rust, Networking, GPU accelerated computing
1w
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Software Automation Engineer
Carlsbad or Marlborough or Linthicum Heights or Tampa
$117k-$185k/yr OnsiteFull Time
2+ YOEBachelor's in CS or similar; 2+ years Java/Python; ability to learn new tech; strong communication; Linux familiarity; active Secret Clearance; onsite in Carlsbad, CA.
Java, Python, Linux, Perforce, Eclipse, Visual Studio, CI/CD, TCP/IP
1mo
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Senior Software Engineer
Burlington, Massachusetts, United States
OnsiteFull Time
Enigma Aerospace: Building autonomous long-range cargo aircraft for heavy-lift logistics.
5+ YOESenior software engineer with 5+ years in backend/autonomy/robotics; proficient in Python and C++; capable of full-stack work, real-time systems; eligible to work in the U.S.
Python, C++, ROS, PX4, UAS, Telemetry, Flight controls, Avionics
5d
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Software Engineer 3
Wilmington, Massachusetts, United States
$97k-$145k/yr OnsiteFull Time
0+ YOE0–5 years experience; degrees in EE, CS, applied mathematics, or physics; strong systems thinking; Python/MATLAB; C/C++/Java; problem solving and communication.
Python, MATLAB, C++, C#, Java
1mo
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Senior Data Engineer
Madison or Boston
$120k-$160k/yr HybridFull Time
3+ YOESenior data engineer with Python, Airflow, DBT, Databricks, C#/.NET; AWS; REST APIs; CI/CD; 3+ years software engineering experience; healthcare experience preferred.
Python, Airflow, DBT, Databricks, C# / .NET, GitHub, AWS, REST APIs, CI/CD, Git
6d
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Senior AI/ML Engineer
New York or Santa Monica or Los Angeles or Palo Alto or Chicago or Washington D.C. or Boston or Colorado or Seattle or San Francisco or San Diego or Reston
OnsiteFull Time
5+ YOE5+ years in AI/ML; hands-on with Azure/AWS; Python; LLMs; data integration; LangChain or similar; cloud security and governance.
Python, Azure, AWS, LangChain, LangSmith, Pydantic AI, APIs, Data Ingestion, Data Lakes, Data Warehouses
1mo
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Software Engineer (Lexington, MA, US)
Lexington or United States
$100k-$150k/yr HybridFull Time
BS in CS/CE or related field; Python; cloud deployment (AWS/Azure); CI/CD; databases; basic ML; Windows/Linux; strong communications.
Python, AWS, Azure, CI/CD, Databases, Go, C#, Java, JavaScript, C/C++, Rust, PowerShell, Bash, Perl, Windows, Linux
2mo
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Staff AI Agent Engineer
Boston or Berkeley
HybridFull Time
6+ YOE6+ years software engineering; Python; backend; LLMs; customer-facing; strong ownership.
Python, APIs, Cloud, LLMs, Agent Frameworks
1mo
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Senior Software Engineer
Boston, Massachusetts, United States
$135k-$165k/yr HybridFull Time
5+ YOE5-7 years of software engineering; Python and Pandas; NumPy/SciPy/statsmodels/scikit-learn; Linux; Git; databases (MS SQL/Postgres/MongoDB); large structured/unstructured data.
Python, Pandas, NumPy, SciPy, statsmodels, scikit-learn, Linux, Git, MS SQL, PostgreSQL, MongoDB, Docker, Kubernetes, Spark, Dask, Redis, Airflow, Kafka, Jenkins, OpenStack, Ansible, Grafana, Prometheus
2mo
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AI / ML Engineer
Cambridge, Massachusetts, United States
OnsiteFull Time
5+ YOE5+ years software engineering with 3+ years ML; strong Python; ML pipelines; data architectures; cloud-native inference; MLOps; healthcare AI interest; safety and bias awareness.
Python, ML frameworks, scikit-learn, Sanic, PyTorch Lightning, Pydantic, LangGraph, Bedrock, OpenAI SDKs, Anthropic SDKs, MLflow, Kubeflow, Kafka, Pub/Sub, Kinesis, RabbitMQ
1w
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Software Engineer (Civil Aviation)
Boston, Massachusetts, United States
OnsiteFull Time
Production-grade backend or distributed systems experience; proficiency in Rust or Python; AWS and cloud-native architectures; data integration and modeling; ability to work across multi-system environments; collaboration in mission-critical settings.
Rust, Python, AWS
HiringCafe market data
Python Developer Jobs market signals in Lowell, MA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
2,100+
Hiring companies
540+
Fresh sample
52% new in 30d
Salary visibility
78% show pay
Companies appearing in this market
Booz Allen HamiltonBAE SystemsBoston DynamicsDigitalOceanGecko RoboticsKlaviyoMan GroupMIT Lincoln Laboratory
Work location mix in visible results
Onsite: 45Hybrid: 35Remote: 16