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Python Developer Jobs in Lowell, MA, US

2,100+ python developer jobs from 540+ companies hiring in Lowell, MA, US.

2,122 jobs- Lowell • 50 miles
1mo
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Sr. Embedded Software Engineer
Somerville, Massachusetts, United States
HybridFull Time
RISE Robotics
RISE Robotics: Develops electric linear actuators to replace hydraulics in heavy machinery.
5+ YOE5+ years in electromechanical product software in C/C++/Python; motion control; read datasheets; CAN/SPI/I2C/UART familiarity.
C, C++, Python, CAN, SPI, I2C, UART
1mo
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Software Automation Engineer
Carlsbad or Marlborough or Linthicum Heights or Tampa
$117k-$218k/yr OnsiteFull Time
Viasat
ViasatNASDAQ: VSAT: Provides global satellite broadband and secure networking communication services.
2+ YOEBachelor’s degree in Computer Science or related field; 2+ years Java or Python; ability to learn new software; strong communication; Linux experience; Active Secret Clearance; onsite in Carlsbad, CA.
Java, Python, Linux, Perforce, Eclipse, Visual Studio, TCP/IP
1mo
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Senior Software Engineer
Boston, Massachusetts, United States
$120k-$180k/yr HybridFull Time
HarbourVest
HarbourVest: Manages global private equity, credit, and infrastructure investments.
5+ YOE5+ years software engineering; BS/BA; experience C#, JavaScript, Python, SQL; Agile; RESTful APIs; Azure; Angular; Snowflake; ASP.NET Core; data integration and governance; strong collaboration.
C#, JavaScript, Python, SQL, ASP.NET Core, Azure, Angular, Snowflake
2mo
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Machine Learning Engineer
Austin or San Francisco or Cambridge
HybridFull Time
Apple
AppleNASDAQ: AAPL: Designs and sells consumer electronics, software, and online services.
4+ YOE4+ years of experience building high-throughput applications or ML models; proficiency in Python/Java/C++; experience with large-scale data and Spark/Snowflake/Hadoop; strong communication and problem solving.
Python, Java, C++, Spark, TensorFlow, Keras, PyTorch, SQL, Snowflake, Hadoop
2mo
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Senior Software Engineer - Autonomy Integrations
Boston or Las Vegas or Pittsburgh or Remote U.S.
$149k-$199k/yr HybridFull Time
Motional
Motional: Developing autonomous vehicle technology for safe and accessible transportation.
Production-grade Python apps, large codebases, CI/CD, modular design, data analysis, collaboration.
Python, C++, Linux, ROS, DDS, Machine Learning
2w
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DBA Developer
Rowley, Massachusetts, United States
HybridFull Time
Harvey Performance Company
Harvey Performance Company: Designing and manufacturing specialized cutting tools for precision machining.
3+ YOE3+ years SQL Server DBA/Developer experience; strong DBA skills; T-SQL proficiency; replication and high availability; automation (PowerShell/Python); cross-team collaboration; proactive mindset.
SQL Server, T-SQL, PowerShell, Python, SSIS, SSRS, SSAS, Redgate tools, DMVs, Extended Events, Performance Monitor
1mo
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Senior Full Stack Developer (React)
New Hyde Park or Moline or Hartford or Framingham or West Palm Beach or Norcross or Chicago or Milwaukee or Baltimore or Piscataway or United States
$125k-$150k/yr RemoteFull Time
Parts Authority
Parts Authority: Distributes automotive and truck replacement parts to the aftermarket industry.
5+ YOE5+ years full-stack production experience; Python (FastAPI/Flask) and React (TypeScript); AI/ML integration; Kafka; PostgreSQL; Redis; strong communication.
Python, FastAPI, SQLAlchemy, Pydantic, React, TypeScript, Tailwind, Redis, PostgreSQL, Kafka, Databricks, MLflow, Docker, Kubernetes, GitHub Actions, Terraform, ODBC, Data Queues, WebSockets, FastAPI, RH other
2mo
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Principal AI Engineer
Louisville or New York City or Tampa or Boston or Dallas or New York City or Washington DC
$172k-$237k/yr HybridFull Time
Humana
HumanaNYSE: HUM: Provides health insurance plans and integrated clinical healthcare services.
10+ YOE10+ years of engineering/software/platform experience; deep Python and cloud-based AI platform experience; 5+ years Kubernetes/Docker; CI/CD and DevOps proficiency; strong ML engineering background.
Python, FastAPI, Flask, REST, gRPC, AWS, GCP, Azure, Docker, Kubernetes, GitLab CI/CD, Jenkins, Kubeflow, ArgoCD, OpenAPI/Swagger, LangChain, LlamaIndex, PydanticAI, PyTorch, TensorFlow
1mo
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Senior Software Engineer
Cambridge or New York
$150k-$225k/yr RemoteFull Time
S&P Global
S&P GlobalNYSE: SPGI: Provides independent credit ratings, market benchmarks, and financial analytics.
5+ YOEFive+ years experience building customer-facing APIs; RESTful API expertise; strong communication; full software development lifecycle.
Python, Flask, FastAPI, Django REST Framework, PostgreSQL, Celery, RabbitMQ, Redis, Kafka, Jsonnet, Claude Code, Codex, Cline, AWS, Amazon EKS, Sentry, Prometheus, Git, Jenkins, Github Actions
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Principal Software Engineer I, Full Stack
Cambridge, Massachusetts, United States
$178k-$209k/yr HybridFull Time
Cambridge Mobile Telematics
Cambridge Mobile Telematics: Providing telematics and behavioral analytics for safer driving and insurance.
7+ YOE7+ years in web technologies, REST APIs, Python/Java, React, AWS; strong system design, mentoring, and leadership; bachelor’s or equivalent.
HTML, CSS, JavaScript, TypeScript, React, Django, Python, Java, AWS, EC2, S3, Lambda, SNS, SQS, RDS, PostgreSQL, NoSQL
1mo
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Senior Software Engineer Staff/Avionics
North Andover, Massachusetts, United States
OnsiteFull Time
Lockheed Martin
Lockheed MartinNYSE: LMT: Designs and manufactures global security and aerospace systems.
Bachelor's degree in Computer Science or related field; C++ or Python experience; ability to obtain DoD Secret clearance.
C++, Python, Software Development Tools
1mo
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GCP AI Engineer - Cambridge, MA
Cambridge, Massachusetts, United States
$143k-$194k/yr HybridFull Time
Lumeris
Lumeris: Providing AI-enabled technology and services for value-based healthcare.
4+ YOEBachelor’s or Master’s in CS/Engineering/AI/Health Informatics; 4+ years in production software/AI/ML with Google Cloud; Python; Docker/Kubernetes; ML pipelines; healthcare exposure.
Python, Vertex AI, Kubeflow, Cloud Build, Terraform, Docker, Kubernetes, LangChain, LangGraph, Gemini APIs, BigQuery, Dataflow, Looker
1mo
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Lead Software Engineer
Boston, Massachusetts, United States
$110k-$159k/yr HybridFull Time
MFS
MFS: Manages mutual funds and investment portfolios for global clients.
5+ YOE5-6+ years in Financial Services; experience with Angular, Java, C#, Python; CI/CD; integration with multi-tier systems; data platforms (Snowflake, Oracle, MS SQL); strong communication and problem-solving.
Angular, Java, C#, Python, Kafka, MQ, Mulesoft, Tableau, PowerBI, SSRS, Snowflake, Oracle, MS SQL
1w
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Staff Software Engineer
Cambridge or New York
$200k-$325k/yr HybridFull Time
Iterative Health
Iterative Health: Develops AI-driven precision medicine for gastrointestinal clinical research.
10+ YOE10+ years software engineering; healthcare data systems; 2+ years in a high-growth startup; strong system integration; ML/AI tooling; data pipelines; backend with Python/SQL; production ML infrastructure.
Python, SQL, Cloud Infrastructure, EHR/EMR integrations, AI tooling
2mo
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Principal Software Engineer
Waltham, Massachusetts, United States
$164k-$257k/yr HybridFull Time
ZoomInfo
ZoomInfoNASDAQ: GTM: Software platform providing B2B data and sales intelligence tools.
5+ YOE5+ years backend, data, or infrastructure engineering; distributed systems, big data infra, or Applied AI/ML expertise; Java, Go, or Python; SQL; experience with ClickHouse, DynamoDB, Bigtable, Kafka, Kinesis, Snowflake.
Java, Go, Python, SQL, ClickHouse, DynamoDB, Bigtable, Memcached, Kafka, Kinesis, Firehose, Airflow, Snowflake, LangGraph, MCP, Copilot, ChatGPT, Claude
1w
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Senior Technical Developer
Weston, Massachusetts, United States
$83k-$182k/yr OnsiteFull Time
Vanguard Renewables
Vanguard Renewables: Produces renewable natural gas from food and dairy waste.
Strong SQL, database development, and Azure cloud experience; hands-on development with C#, Python, Angular; ability to lead and coordinate offshore and onshore teams; strong analytical and problem-solving skills.
C#, \\.NET, Python, Angular, Azure, Azure SQL, SQL
1w
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Senior Software Engineer
Boxborough, Massachusetts, United States
HybridFull Time
Ralliant
RalliantNew York Stock Exchange: RAL: Sells precision instruments and sensors for diverse industrial sectors.
5+ YOE5-10 years of software engineering in C++ on Linux; embedded Linux; cross-build; QT; MQTT/Kafka; architecture and secure development.
C++, Linux, Qt, cmake, Python, Shell, MQTT, Kafka, RabbitMQ, ARM cross-compilation, CI/CD
3w
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Principal Software Engineer, DAAS
Boston, Massachusetts, United States
$164k-$280k/yr HybridFull Time
athenahealth
athenahealth: Cloud-based software for medical practice management and electronic records.
10+ YOESenior software engineer with PostgreSQL expertise, Java/Spring and Python, AWS, Terraform, Docker, EKS, CI/CD, observability, and AI integration; 10+ years experience.
Java/Spring, Python, Terraform, AWS, Docker, EKS, Liquibase, Flyway, PostgreSQL, CI/CD
1mo
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Software Engineer I, Instrument Software
Cambridge, Massachusetts, United States
$108k-$140k/yr OnsiteFull Time
Lila Sciences
Lila Sciences: Develops an AI platform for autonomous scientific research and discovery.
Proficiency in Python or C#/.NET, strong debugging and problem-solving, and clear communication; hardware-software integration experience a plus.
Python, C#/.NET, Git, API development, Hardware-software integration
4d
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Embedded Firmware Engineer
Carson City or Webster or Harbor City or Platform or Jessup or Clinton or Newark or Longmont
$79k-$150k/yr OnsiteFull Time
Vitesse Systems
Vitesse Systems: Designs and manufactures antenna and thermal systems for defense.
2+ YOEBS or MS in Electrical Engineering or related robotics field; 2+ years Level I, 5+ Level II, 8+ Level III firmware/embedded software; C++, Python; RTOS; hardware bring-up; ITAR compliance.
C++, Python, C, VHDL, Verilog, Linux, RTOS, ROS, Git, EtherCAT, SPI, CAN, I2C, UART, RS-232
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Machine Learning Engineer
Boston, Massachusetts, United States
HybridFull Time
Harvard University
Harvard University: Provides higher education and conducts advanced academic research.
7+ YOESeven+ years of post-secondary education or relevant work experience; Masters/PhD strongly preferred; Python ML stack (PyTorch, NumPy); experience with large medical datasets and LLMs; collaboration with clinicians and researchers; track record of publications.
Python, PyTorch, NumPy, Weights & Biases, APIs
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Sr Backend Software Engineer
Boston, Massachusetts, United States
$140k-$150k/yr HybridFull Time
Vista Higher Learning
Vista Higher Learning: Provides digital and print language learning materials for schools.
7+ YOE7+ years as a Senior Software Engineer with Ruby/Rails or Python + JavaScript; architecture, APIs, SQL, AWS; strong LLM and networking knowledge; collaborative, communicative; BS degree.
Ruby on Rails, Python, JavaScript, MySQL, PostgreSQL, Redis, Elasticsearch, AWS, Git
4w
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AWS Test Automation Engineer
Boston, Massachusetts, United States
HybridFull Time
Systems Engineering Solutions
Systems Engineering Solutions: IT consulting and engineering services for federal government agencies.
8+ YOEBachelor's degree in a technical field; 8+ years in test automation and CI/CD; Java/Python; AWS and IaC testing; DoD security requirements; active Secret clearance.
Java, Python, Jenkins, GitLab CI, GitHub Actions, Terraform, CloudFormation, Docker, Kubernetes, AWS, Selenium, JUnit, TestNG, PyTest
2mo
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Senior Full-Stack Engineer
Boston, Massachusetts, United States
RemoteFull Time, Contract
Human Agency
Human Agency: Develops custom artificial intelligence software and organizational AI strategies.
Senior Full-Stack Engineer with Python, Ruby on Rails, secure systems, AI/ML integration, and frontend experience (React/Vue); DevOps and enterprise-facing SaaS work.
Python, Ruby on Rails, OpenAI APIs, LangChain, Hugging Face, Pinecone, Weaviate, React, Vue, Snowflake
2w
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AI & Informatics Engineer
Cambridge, Massachusetts, United States
$134k-$163k/yr OnsiteFull Time
Prime Medicine
Prime MedicineNASDAQ: PRME: Developing precision gene editing therapies to treat genetic diseases.
3+ YOEBS with 5+ years or MS with 3+ years in Engineering, Bioinformatics, Data Sciences, or related field; strong Python, Nextflow, Docker, AWS, Linux/Unix, Git; NGS pipelines; benching/informatics; APIs/SDKs; familiarity with LLM frameworks.
Python, Nextflow, Docker, AWS, Linux/Unix, Git, Benchling, APIs, SDKs
1mo
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Senior Principal Machine Learning Engineer
Boston, Massachusetts, United States
$165k-$296k/yr HybridFull Time
Autodesk
AutodeskNASDAQ: ADSK: Developing software for architecture, engineering, and entertainment industries.
10+ YOE10+ years in ML/AI with leadership, hands-on delivery of large-scale ML systems, expertise in PyTorch, distributed training, Python.
Python, PyTorch, DeepSpeed, Megatron, CUDA, Ray
6d
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Senior Software Engineer
Needham, Massachusetts, United States
$145k-$155k/yr HybridFull Time
Alarm.com
Alarm.comNasdaq: ALRM: Provides cloud-based smart home security and automation solutions.
5+ YOEBachelor's degree in CS/CE or equivalent experience; 5+ years software development; leadership and mentoring; strong OOP; C#/.NET Core; database design.
C#, .NET Core, SQL, Kafka, Ember.js, Node.js, Python, Kubernetes, Azure, Redis, Artemis, iOS, Android
2mo
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Quantum Pro Software Engineer
Calabasas or Everett or Santa Clara or Cambridge
$120k-$199k/yr OnsiteFull Time
Keysight Technologies
Keysight TechnologiesNYSE: KEYS: Provides electronic design, test, and simulation software and hardware.
Bachelor’s/Master’s/PhD in CS/EE/Physics; strong C++/Python; Agile; production-quality software; good communication.
C++, Python
5d
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Software Engineer Intern
Portsmouth, New Hampshire, United States
OnsiteInternship
Sprague Energy
Sprague Energy: Supplies refined petroleum, natural gas, and material handling services.
Pursuing or recently completed degree in Computer Science or related field; basic programming knowledge; ability to learn and collaborate; experience with AI-assisted development tools (preferred).
Python, Java, JavaScript, Git, AI-assisted development tools (Copilot, Codex, Claude Code), APIs (OpenAI)
1mo
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Senior Machine Learning Engineer
Boston, Massachusetts, United States
OnsiteFull Time
Hike Medical
Hike Medical: Produces custom 3D-printed medical orthotics using AI foot scanning.
PhD or equivalent; deep 3D representation expertise; Python and PyTorch; AWS experience; CAD/geometry a plus; Biomedical AI valued.
Python, PyTorch, AWS, SageMaker, Lambda, CAD, 3D Reconstruction
4w
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Principal Software Test Engineer
Mounds View or Newton
$120k-$180k/yr OnsiteFull Time
Medtronic
MedtronicNew York Stock Exchange: MDT: Develops and manufactures medical devices and digital health solutions.
7+ YOEBachelor’s or higher with extensive software test experience; strong automation, UI testing, programming in Python/C++, QT/QML; Git and Agile; experience with test frameworks and cross-domain collaboration.
Python, C++, C#, QT, Git, Ranorex, Appium, Katalon, Squish, Polarion, TFS, TestRail, JAMA
2w
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Senior Software Engineer
Boston, Massachusetts, United States
$153k-$201k/yr HybridFull Time
Franklin Templeton
Franklin TempletonNYSE: BEN: Global investment firm providing asset and wealth management services.
3+ YOEMaster's degree in Computer Science or related field; minimum 3 years of experience with Java and Python; experience with microservices, cloud native architectures, CI/CD, and security; knowledge of market data APIs and AWS/Snowflake/AngularJS/NodeJS; strong debugging, architecture, and Agile practices.
Java, Python, AWS, Snowflake, SQL, AngularJS, NodeJS, Jenkins, GitLab CI/CD, Harness, Docker, Kubernetes, Okta, Bloomberg, Refinitiv
3w
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Database Developer
Pittsburgh or Boston
HybridFull Time
Confluence
Confluence: Software for investment management data and regulatory reporting.
Expert-level Microsoft SQL Server; advanced SQL/T-SQL; performance optimization; analytics data modeling; investment performance domain knowledge.
Microsoft SQL Server, T-SQL, Python, AI-assisted development tools, SQL performance tuning, Analytics databases
3d
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Senior AI Engineer, AI Solutions
Boston, Massachusetts, United States
$144k-$181k/yr HybridFull Time
CarGurus
CarGurusNASDAQ: CARG: Operates an online marketplace for buying and selling vehicles.
5+ YOE5+ years software engineering; Python; API design; AWS; experience with AI/LLM APIs and production-grade systems; cross-functional collaboration; autonomy.
Python, AWS, LLM APIs, Anthropic/Claude, AWS Bedrock, Salesforce
3d
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Robotics Software Engineer - ML and Grasping
Charlestown, Massachusetts, United States
$110k-$135k/yr HybridFull Time
Pickle Robot
Pickle Robot: Automated robotic systems for unloading trucks and containers.
Hands-on ML and robotics software experience; strong Python; cloud knowledge (GCP); BS in Robotics/CS; MS preferred.
Python, GCP, Isaac Sim, MuJoCo
1mo
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Senior Machine Learning Engineer
Natick, Massachusetts, United States
$115k-$225k/yr HybridFull Time
Cognex
CognexNASDAQ: CGNX: Manufactures machine vision systems and industrial barcode readers.
5+ YOEExperience designing, training, and deploying deep learning models for computer vision; strong Python/C++; knowledge of PyTorch/TensorFlow; embedded systems experience.
Python, C/C++, PyTorch, TensorFlow, Git, CI/CD
3w
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AI/ML Research Engineer
Boston or San Francisco
OnsiteFull Time
Manifold Bio
Manifold Bio: Designing tissue-targeted protein therapeutics using AI and in vivo screening.
2+ YOE2+ years with PyTorch/JAX; Python stack; distributed computing; protein/computational biology familiarity; Git; independent problem solving; strong communication.
Python, PyTorch, JAX, NumPy, Pandas, scikit-learn, Git
1mo
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Forward Deployed Engineer
Boston or New York or Palo Alto
$70k-$100k/yr HybridFull Time
Workato
Workato: Enterprise platform for automating business workflows and integrating applications.
4+ YOE4+ years in design/development/implementation; 1+ year with Workato or similar orchestration platform; BTech/BE or higher in CS/AI/ML; proven AI engineering experience; strong integration and API knowledge.
Workato, TIBCO, Dell Boomi, MuleSoft, APIs, JSON, Java, Python, Ruby, SOA, ESB, BPM, RPA, Cloud platforms
1mo
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AI Engineer (Leawood, KS, US, 66211)
Leawood or Burlington
HybridFull Time
Ascend Learning
Ascend Learning: Provides educational software and certifications for healthcare professionals.
3+ YOE3+ years AI or software engineering; BS in CS/AI/Software Eng or related; Azure AI Engineer cert preferred; Python/REST (FastAPI); ML/LLM experience; distributed systems.
Python, FastAPI, Docker, Kubernetes, CI/CD, Azure, Apache Kafka, Angular, React, REST API
2mo
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Senior Software Engineer
Waltham, Massachusetts, United States
$147k-$198k/yr OnsiteFull Time
Markforged
Markforged: Manufactures industrial 3D printers and high-strength materials.
5+ YOE5+ years in software development; BS in Computer Science or equivalent; strong full-stack JS/TS; experience with React/Node; UX prototyping with Figma; AWS/GCP/Azure; PostgreSQL; clear communication.
Node.js, Express, React, Angular, Vue.js, Python, Django, Flask, PostgreSQL, AWS, GCP, Azure, Figma, WebGL, Three.js, D3

HiringCafe market data

Python Developer Jobs market signals in Lowell, MA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
2,100+
Hiring companies
540+
Fresh sample
43% new in 30d
Salary visibility
71% show pay

Companies appearing in this market

AppleCambridge Mobile TelematicsHarvard UniversityHumanaLila SciencesMFSMotionalViasat

Work location mix in visible results

Hybrid: 50Onsite: 29Remote: 7