📣 HiringCafe is hiring a Founding Growth Hacker! Learn More · Apply here
Limited-index browse page
Python Developer Jobs in Mendon, MA, US
2,000+ python developer jobs from 530+ companies hiring in Mendon, MA, US.
2mo
Save
Mark Applied
Hide
Software / Computer / Robotics Engineer – PLC & Control Systems, Ocean Products
Chelmsford, Massachusetts, United States
$75k-$115k/yr OnsiteFull Time
2+ YOEBachelor's degree in CS/CE/Robotics; 2+ years; PLC/HMI/VFD; control systems; hardware interfacing; prototyping; strong communication.
PLC programming, HMI programming, VFD programming, MATLAB, LabVIEW, Wago controllers, C/C++, Python, TCP/IP networking, DAQ, signal conditioning
2w
Save
Mark Applied
Hide
Financial Advisory Senior AI Solution Architect (Nationwide, Remote)
New York or Denver or Georgia or Pennsylvania or Boston or Chicago or Houston or Dallas or Seattle or Detroit or New Jersey or California
$165k-$215k/yr RemoteFull Time
8+ YOE8–12 years in software engineering/AI development; Python expert; experience with LLM APIs, document processing; cloud deployments (AWS/Azure); CI/CD; strong communication.
Python, LLM APIs, API development, PowerPoint, Excel, AWS, Azure, Git, Seismic, Salesforce, OpenSearch, SQL, python-pptx, openpyxl
2w
Save
Mark Applied
Hide
Firmware Engineering Co-Op - Fall 2026
Boston, Massachusetts, United States
$42/hr HybridAll Commitments Available
Enrolled in computer engineering, computer science, or related engineering; experience with C and Python; firmware development; embedded systems; hardware debugging; knowledge of I2C, SPI, UART; collaboration across teams.
C, Python, JTAG, Oscilloscope, Multimeter, Bus Analyzer, I2C, SPI, UART
18h
Save
Mark Applied
Hide
Capgemini Invent / Cambridge Consultants - Engineering Co-op - Embedded Software (Burlington, MA, US)
Burlington, Massachusetts, United States
$20-$35/hr OnsiteInternship
0+ YOEPursuing BS or MS in electrical, computer engineering, computer science, or related fields; some software development experience; C/C++/Rust; MATLAB or Python; good testing and communication skills.
C, C++, Rust, MATLAB, Python
2mo
Save
Mark Applied
Hide
Associate Principal/Forensic AI Engineer (Forensic Services practice)
Boston or Chicago or New York or Washington
$140k-$170k/yr HybridAll Commitments Available
8+ YOE8–10+ years in ML/AI, digital forensics, or related field; expertise in LLMs, synthetic media, and AI governance; strong communication for legal settings.
Python, PyTorch, TensorFlow, pandas, NumPy, scikit-learn, SQL, OpenCV, Docker, Kubernetes, AWS SageMaker, GCP Vertex AI, Azure Machine Learning, LangChain, LlamaIndex, Transformers, PEFT, DALL·E, Ffmpeg, Pinecone, Weaviate, ChromaDB, pgvector, Spark, Airflow, Snowflake, BigQuery, Redshift
1mo
Save
Mark Applied
Hide
Machine Learning Research Scientist, Mechanical Intuition in Multimodal Models
Los Altos or Cambridge
$158k-$253k/yr HybridFull Time
PhD in a related field, strong ML pipeline development, experience with policy/ RL, Python proficiency, interest in manufacturing.
Python, Reinforcement Learning, Robotics
1mo
Save
Mark Applied
Hide
AI Specialist
Boston, Massachusetts, United States
OnsiteFull Time
Hands-on AI development, building internal AI tools, experience with LLMs, data pipelines, Python, cloud (AWS/GCP/Azure), CRM familiarity, and strong collaboration with compliance and cross-functional teams.
Python, AWS, Google Cloud Platform, Azure, Creatio, CRM, Slack, SharePoint, Notion, ETL, AI frameworks
3w
Save
Mark Applied
Hide
Principal Platform Data Engineer, SAP (Cambridge, MA, US, 02142)
Cambridge, Massachusetts, United States
$175k-$237k/yr HybridFull Time
10+ YOE10+ years in data engineering; 5+ years SAP data extraction, integration, and analytics; strong SAP domain knowledge; expert in SAP extraction methods and Snowflake/dbt-based pipelines; familiarity with regulated environments.
SAP, Snowflake, dbt, Fivetran, ABAP CDS, S/4HANA, BW/4HANA, SQL, Python, Terraform, GitHub Actions, AWS, Monte Carlo
3mo
Save
Mark Applied
Hide
Security Researcher / Systems Hacker
Lexington, Massachusetts, United States
$140k-$200k/yr OnsiteFull Time
3+ YOEMS or PhD in a related field with extensive systems software research and development experience; strong C/C++, Python, and assembly; security clearance eligibility.
C/C++, Python, Assembly, Rust, LLVM, QEMU, Linux
3w
Save
Mark Applied
Hide
Technology Consultant 1
Boston or Princeton
$62k-$95k/yr OnsiteFull Time
Hands-on cloud experience (AWS/Azure/GCP), DevOps, Linux/Windows servers, Python/Shell scripting; IAM, Terraform, containers; Bachelor's degree or equivalent; willing to relocate/travel; US work authorization.
AWS, Azure, GCP, Terraform, Python, Linux, Docker, Kubernetes
2mo
Save
Mark Applied
Hide
Post Doc - Open Rank
Worcester, Massachusetts, United States
$62k-$76k/yr OnsiteFull Time
PhD in computational biology or related field; method development or sequencing data experience; Unix/Linux and programming (C/C++, Python, Perl, R); strong communication; publications; able to work independently and in teams.
Unix, Linux, C, C++, Python, Perl, R
2w
Save
Mark Applied
Hide
Catastrophe Research Manager
New York or Boston or Philadelphia or Chicago
$105k-$150k/yr OnsiteFull Time
6+ YOE6+ years catastrophe research or model development; PhD or Master’s in Climate Science, Natural Hazards, Applied Statistics; strong RMS background; proficient in R, Python, SQL; excellent communication; experience with model reviews and validation.
R, Python, SQL
2mo
Save
Mark Applied
Hide
Scientist I, Peptide Drug Discovery
Cambridge, Massachusetts, United States
$110k-$125k/yr OnsiteFull Time
0+ YOEPhD in Chemical Biology, Biochemistry, Chemistry, or Bioengineering; 0-2 years postdoc/industry; hands-on assay development; automation and scripting experience; ability to work cross-functionally; proficient with Python; strong data QC mindset.
Python
1mo
Save
Mark Applied
Hide
Associate Director, MLOps (Staff AI / ML Engineer) - Hybrid
Waltham, Massachusetts, United States
$158k-$180k/yr HybridFull Time
7+ YOESenior ML/AI leader with 7+ years (MS/PhD) or 10+ years (BS) in data science/ML; strong Python, MLOps, and cloud skills; generative AI experience; able to lead cross-functional teams.
Python, Airflow, Prefect, Docker, Github, Github Actions, DataDog, AWS, GCP, LangGraph, Pydantic, FastAPI, Snowflake Cortex, DBT, Spark
1mo
Save
Mark Applied
Hide
Manager, Engineering
Raleigh or Chicago or Franklin or Boston
$148k-$175k/yr HybridFull Time
5+ YOE5+ Mgmt5+ years of technical leadership; 5+ years in operations optimization; tests, reports, and documentation experience; strong Python, Django, PySpark, ETL, SQL skills.
Python, Django, PySpark, ETL, SQL
1w
Save
Mark Applied
Hide
Member of Technical Staff - Product Engineer (Internal Data & Agent Platform)
San Francisco or Cambridge or Germany
HybridFull Time
5+ YOE5+ years software engineering; experience building data pipelines, integrations, or internal platforms; hands-on LLM production experience; strong Python; TypeScript for frontend/tooling; experience integrating SaaS APIs.
Python, TypeScript, Slack API, GitHub API, Google Workspace API, HRIS API
2w
Save
Mark Applied
Hide
Associate Director, Programming (Macros & Automation)
King of Prussia or Waltham or Glattbrugg
$189k-$220k/yr HybridFull Time
10+ YOE10+ years SAS programming, macro development, and automation leadership; knowledge of CDISC; strong collaboration.
SAS, SAS Macro, Python, R
3d
Save
Mark Applied
Hide
Senior Tools Programmer
Boston, Massachusetts, United States
$119k-$218k/yr HybridFull Time
Extensive production C++ experience; full lifecycle tool development; strong communication; prioritize and deliver value.
C++, Unreal Engine, Slate, Editor Utility Widgets, Python, Blueprint
1mo
Save
Mark Applied
Hide
Staff Computational Biologist
Lexington or United States
$166k-$195k/yr HybridFull Time
6+ YOE6+ years in computational biology/data-driven discovery; 1+ year in software/data engineering; Python and R; omics/translational analysis; ETL pipelines; product-owner experience.
Python, R, Omics data analysis, ETL pipelines
2mo
Save
Mark Applied
Hide
Analog Design Automation Intern
Toronto or Boston or Austin or Santa Clara
$35-$70/hr HybridInternship
Co-op or PEY student in Electrical Engineering with analog IC design exposure; Python proficiency; interest in ML concepts; open source tools; strong analytical and communication skills.
Python
2mo
Save
Mark Applied
Hide
Solutions Architect
Boston or San Francisco
HybridFull Time
Strong systems thinking and coding; production systems; Python/Go/C++; web frameworks; PostgreSQL/Redis; REST/GraphQL; PyTorch/JAX; Kubernetes/Docker; Terraform; HPC/physics interest.
Python, Go, C++, React, TypeScript, Next.js, PostgreSQL, Redis, REST, GraphQL, PyTorch, JAX, Ray, Airflow, Argo, Docker, Kubernetes, Terraform, Prometheus, Grafana
1mo
Save
Mark Applied
Hide
Manager, Data Science (GenAI Solutions & ML Engineering) (Boston, MA, US, 02110)
Boston, Massachusetts, United States
$131k-$164k/yr OnsiteFull Time
5+ YOE3+ MgmtBachelor’s degree; 5+ years in Machine Learning Engineering, Applied AI, or MLOps; 3+ years leading technical teams; strong end-to-end AI systems; Python and PyTorch; enterprise integration.
Python, PyTorch, ML frameworks
4d
Save
Mark Applied
Hide
Brain Computer Interface R&D Intern - Brain proxy development
Cambridge, Massachusetts, United States
OnsiteAll Commitments Available
Pursuing or recently completed degree in bioengineering, mechanical engineering, or related field; CAD experience; Python/data analysis helpful; CPT-eligible for international students.
Onshape, SolidWorks, Fusion 360, 3D printing, Python
1mo
Save
Mark Applied
Hide
Senior Scientist – Computational siRNA Lead Development
Dublin or Boston or Stevenage
RemoteFull Time
2+ YOEPhD in computational biology or related; extensive drug discovery in RNA-targeted therapeutics; hands-on transcriptome off-target analysis; strong Python/R; experience building computational workflows.
Python, R, RNA-seq analysis
1w
Save
Mark Applied
Hide
Pioneering Intelligence Machine Learning Co-Op
Cambridge, Massachusetts, United States
$25-$40/hr OnsiteInternship
Fluency in Python with deep learning (PyTorch/JAX); ability to dive into biology/chemistry/physics of platform companies.
Python, PyTorch, JAX, Git, AWS, GCP, Azure
1mo
Save
Mark Applied
Hide
Research Intern – Advanced Solution Development
Framingham, Massachusetts, United States
OnsiteInternship
Master’s or PhD candidate in CS or related field; strong AI/ML background; proven research ability; prior software development preferred.
LLM, Python, Machine Learning, Research Frameworks
1mo
Save
Mark Applied
Hide
Process Development Principal Scientist
Cambridge, Massachusetts, United States
$155k-$184k/yr OnsiteFull Time
2+ YOEPhD/PharmD/MD with 2+ years, or MSc with 5 years, or BSc with 7 years; strong drug product formulation and process development, regulatory submissions.
Python, R, MATLAB, SQL, Tableau, Spotfire, D3js, SAS, JMP, Minitab
3mo
Save
Mark Applied
Hide
Internship - Active SLAM for Aerial Robots
Cambridge, Massachusetts, United States
$6k-$8k/mo OnsiteInternship
PhD student in engineering/CS with hands-on aerial-robot experience; ROS2, Python/C++, and strong research potential.
Python, C++, ROS2, Isaac Sim, MuJoCo
3mo
Save
Mark Applied
Hide
Computational Scientist I - Computational Biology
Cambridge, Massachusetts, United States
$88k-$124k/yr OnsiteFull Time
1+ YOEPhD in computational fields; 1+ year postdoctoral experience; Python/R programming; ML knowledge; NGS pipelines expertise.
Python, R, Machine Learning, Single-cell RNA-Seq, Single-cell ATAC-Seq, Spatial Transcriptomics, Genomics, Bioinformatics
2mo
Save
Mark Applied
Hide
Scientist II, Bioinformatics
Lexington, Massachusetts, United States
$126k-$158k/yr OnsiteFull Time
Cystic Fibrosis Foundation: Funds medical research and provides support for cystic fibrosis.
PhD or Master’s with 5+ years in computational research; experience with NGS, multi-omics, R/Python, ML; strong communication.
R, Python, Shell, Linux, Git
2mo
Save
Mark Applied
Hide
Algorithmic Trading Internship - Boston Summer 2026
Boston, Massachusetts, United States
$50/hr RemoteInternship
Strong problem-solving, programming (Python/C#/Java/C++), curiosity, collaboration, interest in financial markets, pursuing master's/PhD in STEM.
Python, C#, Java, C++
1w
Save
Mark Applied
Hide
Scientist I - R&D Next Generation Sequencing
Westborough, Massachusetts, United States
$100k-$115k/yr OnsiteFull Time
1+ YOEPhD in Molecular Biology/Genetics/Biochemistry/Chemistry or Biomedical Engineering; 1+ years in molecular assays/NGS; 6+ months in R or Python.
Next Generation Sequencing, R, Python, Bioinformatics, Molecular Diagnostics
1mo
Save
Mark Applied
Hide
Intern, Computational Biology
Boston, Massachusetts, United States
$30-$33/hr OnsiteInternship
Pursuing PhD/MS in relevant field or BS with industry experience; modeling biology; Python; Unix; HPC/cloud a plus; strong collaboration.
Python, Git, Linux, AWS, HPC, Shell Scripting
16h
Save
Mark Applied
Hide
Scientist II, Cheminformatics
Cambridge, Massachusetts, United States
$88k-$126k/yr OnsiteFull Time
2+ YOEPh.D. or M.S. in Organic Chemistry with 2–5 years of industry experience; strong synthetic chemistry, familiarity with cheminformatics, Python/RDKit; collaborative and communicative.
Python, RDKit, Cheminformatics tools
1mo
Save
Mark Applied
Hide
Scientist II, Computational Biology & AI
South Boston, Massachusetts, United States
$140k-$150k/yr OnsiteFull Time
2+ YOEPhD in computational biology or related field; 2+ years industry/postdoc in AI/ML for genomics; strong Python; experience with sequencing data and ML pipelines.
Python, C++, R, Julia, PyTorch, TensorFlow, scikit-learn, BWA, SAMtools, GATK, IGV, Illumina, PacBio, Oxford Nanopore, 10x Genomics, Linux, AWS
5d
Save
Mark Applied
Hide
Sr. Scientist, Predictive Immune Biomarkers
Cambridge, Massachusetts, United States
$131k-$207k/yr OnsiteFull Time
5+ YOEPhD in computational biology or related field; 5+ years multi-omics analysis; strong programming in R/Python/Bash; HPC and AWS experience; excellent communication.
R, Python, Bash, HPC, AWS
1w
Save
Mark Applied
Hide
Associate AI Security Resident
Washington or San Francisco or Santa Monica or Pittsburgh or Boston
$90k-$177k/yr HybridFull Time
1+ YOETechnical security/engineering background; leadership experience; programming in Python/Java/C/C++; threat modeling; strong communication; policy analysis; collaboration; MS Office.
Python, Java, C/C++, Threat modeling, MS Office
4d
Save
Mark Applied
Hide
Wildfire Scientist - Impact Forecasting
Boston, Massachusetts, United States
$115k-$140k/yr HybridFull Time
MS or PhD in meteorology/climate science; strong programming in R/Python; experience with numerical/weather/climate models; geospatial data; CAT modeling experience preferred.
R, Python, ArcGIS, QGIS, SQL
4w
Save
Mark Applied
Hide
Principal Machine Learning Scientist (Cambridge, Massachusetts, US)
Cambridge, Massachusetts, United States
$124k-$186k/yr OnsiteFull Time
5+ YOEPh.D. in a life sciences/computer science field; deep ML expertise for biomolecular modeling; large dataset experience; Python proficiency; strong communication; self-motivated.
Python, Machine Learning, Deep Learning, Molecular Dynamics, Rosetta
1w
Save
Mark Applied
Hide
Manager of Travel Model Development
Boston, Massachusetts, United States
$115k-$125k/yr OnsiteFull Time
Lead and manage a travel model development team; oversee modeling tools; strong Python, GitHub, AI approaches; project and team management; transportation domain knowledge preferred.
Python, GitHub, Caliper GISDK
HiringCafe market data
Python Developer Jobs market signals in Mendon, MA, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
2,000+
Hiring companies
530+
Fresh sample
45% new in 30d
Salary visibility
85% show pay
Companies appearing in this market
AmgenBroad InstituteMerck & Co.Mitsubishi Electric Research LaboratoriesAIGLiquid AIAlnylamBayer
Work location mix in visible results
Onsite: 35Hybrid: 23Remote: 4