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Python Developer Jobs in San Mateo, CA, US

6,700+ python developer jobs from 1,100+ companies hiring in San Mateo, CA, US.

6,760 jobs- San Mateo • 50 miles
1mo
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Software Engineer, AI team (all levels)
San Francisco, California, United States
$160k-$240k/yr HybridFull Time
Zip
Zip: AI platform for orchestrating enterprise procurement and business spend.
2+ YOE2+ years of relevant experience; BS or higher in CS or related field; web app/API development; Python, JavaScript, React, GraphQL; Kubernetes, Spinnaker, Jenkins, Kibana, Prometheus, Grafana.
Python, JavaScript, React, GraphQL, Kubernetes, Spinnaker, Jenkins, Kibana, Prometheus, Grafana
1mo
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Lead Software Engineer
San Francisco, California, United States
OnsiteFull Time
Clockwork Systems
Clockwork Systems: Software-driven network fabrics for GPU cluster performance optimization.
7+ YOE7+ years in software engineering or systems development; CS/EE degree; proficient in C/C++, Go, Java, Python; strong debugging; experience with large distributed systems; cloud platforms (AWS/GCP/Azure); networking; full stack.
C, C++, Go, Java, Python, AWS, GCP, Azure, Networking, Databases, Observability, Containers, Kubernetes
1mo
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Forward Deployed Engineer
New York City or San Francisco
$180k-$300k/yr OnsiteFull Time
Hebbia
Hebbia: AI platform for financial research and document analysis.
5+ YOE5+ years software development; full-stack across APIs, data pipelines, frontend, or infrastructure; AWS; Python, TypeScript, Go; data integrations and enterprise data systems; customer-facing engineering experience; finance/domain knowledge a plus.
AWS, Python, TypeScript, Go, Snowflake, SharePoint, S3
1mo
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Runtime Engineer
Palo Alto, California, United States
OnsiteFull Time
SambaNova Systems
SambaNova Systems: Develops custom AI hardware and software for enterprise computing.
3+ YOE3-5 years of industry experience; strong C/C++ and Python; experience with distributed systems and kernel drivers.
C/C++, Python, kernel drivers, distributed systems
3w
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AI Engineer
New York City or San Francisco or Columbus or Remote
RemoteFull Time
ReadMe
ReadMe: Platform for creating interactive developer hubs and API documentation.
Experience building with LLMs in production; strong JS/TS or Python; familiarity with embeddings, retrieval, and API-driven systems.
JavaScript, TypeScript, Python, OpenAPI, JSON, LLMs, Embeddings, Retrieval systems, APIs
1mo
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Senior Software Engineer - API Experience
San Francisco or San Jose or Seattle
$266k-$445k/yr HybridFull Time
Lambda
Lambda: Provides high-performance GPU cloud infrastructure for AI development.
Backend and frontend development of core cloud APIs and services; experience with Python, Django or FastAPI, Postgres; strong collaboration across teams; ability to own features end-to-end.
Python, Unix/Command Line, Django, FastAPI, PostgreSQL, AWS, Okta, Cloudflare, Kubernetes, Terraform, Atlantis, Crossplane, ML/AI experience, Application security
1mo
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Junior Software Developer
Burlingame, California, United States
$95k-$125k/yr OnsiteFull Time
Xona Space Systems
Xona Space Systems: Operates low Earth orbit satellites for high-precision navigation services.
Proficiency in C/C++, Bash, Python; knowledge of SPI, I2C, UART; experience with hardware interaction and embedded testing preferred.
C/C++, Bash, Python, SPI, I2C, UART
1d
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Software Developer I - Integration/Automation Developer
Oakland, California, United States
$29-$45/hr HybridFull Time
Astreya
Astreya: Provides managed IT services and digital workplace solutions for enterprises.
Entry-level integration/automation developer with degree in engineering or computer science; coding experience; REST APIs; AWS; and collaboration with offshore teams.
GitHub, VS Code, GitHub Copilot, Python, Node.js, AWS, REST APIs
5h
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Staff Backend Software Engineer
San Francisco or Cambridge
$180k-$225k/yr OnsiteFull Time
Lumafield
Lumafield: Accessible industrial CT scanners and cloud-based analysis software
10+ YOE10+ years backend software development; expert Python, Django/DRF; PostgreSQL, AWS (S3, RDS/Aurora, IAM); Celery; Kubernetes; Docker; SOC2/ISO27001 security familiarity; scalable cloud architectures.
Python, Django, DRF, Celery, PostgreSQL, AWS, S3, Aurora, IAM, VPC, SageMaker, Kubernetes, Docker
1mo
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Full Stack Engineer
Sunnyvale, California, United States
$120k-$160k/yr OnsiteFull Time
Knightscope
KnightscopeNASDAQ: KSCP: Manufactures autonomous robots and communication devices for physical security.
Proficient in Node.js, React/Redux, ES6, HTML5, CSS3; RESTful APIs; backend in Python/Java/JavaScript; SQL and NoSQL databases; Git; live media streaming tech; Axis cameras/API integration; AWS; AI-assisted development tools.
Node.js, React, Redux, ES6, HTML5, CSS3, Python, Java, JavaScript, REST API, Django, Flask, Rails, MySQL, MongoDB, Amazon DocumentDB, Git, Axis VAPIX, ONVIF, AWS S3, HLS, WebRTC, Claude AI, GitHub Copilot, Tabnine, Three.js, Babylon.js, Cesium, WebGL
4w
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Associate Software Engineer
Santa Clara, California, United States
HybridFull Time
NICE
NICENASDAQ: NICE: Provides AI-powered software for customer engagement and financial compliance.
2+ YOEBachelor’s degree in Computer Science or related field; 2+ years backend development; proficient in Java and Python; relational databases (MySQL, PostgreSQL); RESTful APIs; messaging with Kafka/RabbitMQ; Agile experience; CI/CD with Jenkins, Docker, Kubernetes; AWS.
Java, Python, MySQL, PostgreSQL, REST, Kafka, RabbitMQ, Jenkins, Docker, Kubernetes, AWS, Github Copilot, pgvector, ChromaDB
1w
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Perception Engineer
Huntington Beach or San Francisco
$125k-$220k/yr OnsiteFull Time
Mach Industries
Mach Industries: Designs and manufactures autonomous unmanned aerial vehicles for defense.
7+ YOEProduction C++ on Linux and Python for ML/tooling; CUDA backends; PyTorch; 7+ years experience in CS/EE/Robotics.
C++, Python, CUDA, TensorRT, ONNX Runtime, PyTorch, Jetson, Linux
1mo
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ML Platform & Infrastructure Engineer
San Francisco, California, United States
OnsiteFull Time
AGI, Inc.
AGI, Inc.: Builds autonomous AI agents for mobile and desktop tasks.
3+ YOEBachelor in CS or equivalent; 3+ years in Software Engineering, MLOps, or ML Infrastructure; Python; experience building internal developer tools; cloud (AWS/GCP) and Docker/Kubernetes.
Python, AWS, GCP, Docker, Kubernetes, Streamlit, Retool
1w
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Senior Software Engineer - AHV (Hypervisor, Kernel, Virtualization)
San Jose, California, United States
$156k-$311k/yr HybridFull Time
Nutanix
NutanixNASDAQ: NTNX: Sells cloud software and hyperconverged infrastructure for enterprises.
C and Python proficiency; Unix/Linux kernel-level experience; virtualization and OS internals knowledge; driver development; open source collaboration.
C, Python, Unix/Linux, Linux kernel, Device drivers, x86 architecture
3w
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Senior Software Engineer, Developer Success
San Francisco, California, United States
$196k-$221k/yr HybridFull Time
Discord
Discord: A platform providing voice, video, and text communication services.
5+ YOE5+ years of software engineering experience; experience with Python, TypeScript/React, or Elixir; strong collaboration and product/design sense; problem solving from first principles; familiarity with AI coding tools.
Python, TypeScript, React, Elixir, AI coding tools
2mo
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Compiler Engineer (Frontend)
San Jose, California, United States
OnsiteFull Time
Persimmons
Persimmons: Develops high-performance, low-power generative AI inference chiplets and infrastructure.
6+ YOE6+ years in compiler development; strong C++ and Python; experience with AI models and scheduling; BS/MS/PhD in CS/CE or related field.
LLVM, MLIR, TVM, XLA, IREE, PyTorch, TensorFlow, JAX, Halide
2mo
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Applied AI Software Engineer
San Francisco, California, United States
$140k-$225k/yr HybridFull Time
DocuSign
DocuSignNASDAQ: DOCU: Provides electronic signature and agreement management software solutions.
5+ YOE5+ years experience building AI agents, AI-assisted development, and software delivery; strong React, Typescript/JavaScript, Python/Java; API integration; cloud (Azure/AWS).
React, Typescript, JavaScript, HTML, CSS, Python, Java, APIs, Cloud (Azure or AWS), LLMs, CI/CD, Git
1mo
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Senior Full Stack Engineer
Burlingame, California, United States
$140k-$195k/yr HybridFull Time
SuperDial
SuperDial: Automates healthcare administrative phone calls with voice AI agents.
5+ YOE5+ years full-stack development; strong Python back-end (FastAPI, Django, Flask); JS/TypeScript with React; API design (REST/GraphQL); databases and system design.
Python, FastAPI, Django, Flask, JavaScript, TypeScript, React, Next.js, REST, GraphQL, AWS, GCP, Celery, Kafka, WebSockets
1mo
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Senior Software Engineer, Intelligent Messaging
San Francisco, California, United States
$190k-$230k/yr RemoteFull Time
Attentive
Attentive: AI-powered SMS and email marketing platform for personalization.
5+ YOE5+ years backend software development; proficient in Java, Python, or Go; experience building scalable, high-performance systems; strong collaboration and practices like code reviews and CI/CD.
Java, Python, Go, AWS, DynamoDB, Kinesis, PostgreSQL, Redis, Kafka, Pulsar, React, TypeScript, Docker, Kubernetes, Terraform, Istio, Datadog, GraphQL, Storybook, Radix UI, Vite, esbuild, Playwright, Python (libraries), HuggingFace, PyTorch, TensorFlow, Pandas
1mo
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Senior Fullstack Engineer, Care Delivery
San Francisco or Palo Alto
$170k-$220k/yr HybridFull Time
Midi Health: Healthcare focused on midlife women's care.
6+ YOE6+ years in full-stack development; expert in Django/Python and React; experience building operational/workflow systems; ownership mindset; automated testing, CI, code quality; mentoring experience.
Django, Python, React
3w
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Software Simulation Engineer
Santa Clara, California, United States
$106k-$170k/yr OnsiteFull Time
Johnson & Johnson
Johnson & JohnsonNYSE: JNJ: Provides pharmaceutical products and medical technology healthcare solutions.
3+ YOEBachelor’s degree in Computer Science, Electrical and Computer Engineering, Mechanical Engineering, or related field; 3+ years post‑academic software development or a Master’s degree; strong C++, Linux, Python, Git; experience in simulation and distributed systems; willingness to travel up to 5%.
C++, Python, Linux, Git, CMake, Docker, Bash, Qt, Networking
1mo
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AI Engineer
San Francisco, California, United States
HybridFull Time
Arbital Health
Arbital Health: Provides infrastructure for adjudicating healthcare value-based care contracts.
3+ YOE3+ years in data-intensive SaaS, >1 year in ML/AI, Python and SQL, experience with AI systems, tooling, and cloud platforms.
Python, R, SQL, Next.js, React, TypeScript, Tailwind CSS, TensorFlow, PyTorch, Hugging Face Transformers, LangChain, LlamaIndex, AWS, GCP, Vertex AI, Airflow, Databricks, GitHub, Jira, Confluence, Figma, Claude, Gemini
1mo
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AI Engineer
San Francisco or New York or Seattle or Chicago
$150k-$180k/yr HybridFull Time
Ironclad
Ironclad: AI platform for digital contract lifecycle management
BS in CS/engineering; experience with LLMs/RAG, embeddings, ML lifecycle; Python, NLP; cloud platforms; Git; strong collaboration and communication.
Python, RESTful APIs, HuggingFace, OpenAI, LangChain, PyTorch, TensorFlow, GCP, AWS, Azure, Git
2w
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Staff Engineer
San Francisco, California, United States
OnsiteFull Time
Emergent Labs
Emergent Labs: Platform for building production-ready applications using autonomous AI agents.
8+ YOE8+ years backend/distributed systems; Python/Go; distributed systems design; ownership of production architecture; AI/ML infrastructure a plus.
Kubernetes, Docker, AWS, GCP, Azure, Python, Go
13h
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Software Engineer
San Francisco, California, United States
$164k-$230k/yr RemoteFull Time
Reddit
RedditNYSE: RDDT: Social platform for community-driven discussion and content sharing.
1+ YOEBachelor's degree in CS/Engineering and 1 year of experience; Kubernetes, Kafka, Argo, MySQL, Grafana, Python, JavaScript, Go, Redis, Git.
Kubernetes, Kafka, Argo, MySQL, Grafana, Python, JavaScript, Go, Redis, Git
6d
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Full Stack Software Engineer - Robotics
Chicago or San Francisco
$115k-$200k/yr HybridFull Time
Formic
Formic: Provides industrial robots for manufacturing via a service-based model.
5+ YOE5+ years in full stack development with Python and modern frontend; strong distributed systems, AI-enabled apps, Linux, AWS; BS in CS or equivalent.
Python, React, React Native, AWS, Grafana, Datadog, Linux
2mo
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AI Developer Experience
Palo Alto, California, United States
$185k-$275k/yr HybridFull Time
Mashgin
Mashgin: AI-powered touchless checkout kiosks for retail and dining.
6+ YOE6+ years coding; BS in Computer Science; proficient in Python, Node.js, C++, Go, C#, Java; experienced building production-ready code.
Python, Node.js, C++, Go, C#, Java
2w
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Staff Software Engineer, Developer Foundations
San Francisco, California, United States
$194k-$267k/yr HybridFull Time
Okta
OktaNASDAQ: OKTA: Provide secure identity management and authentication for enterprises.
5+ YOEBuild CI/CD tools and pipelines; 5+ years of experience; proficient with Java, Jenkins, AWS, Docker; familiar with Python, Node, iOS, Ruby, Bash, Go; cross-functional collaboration; BS in CS or equivalent.
Java, Jenkins, AWS, Docker, Python, Node, iOS, Ruby, Bash, Go, Gradle, Bazel, Artifactory, NPM, Docker registry
2mo
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Senior/Staff Software Engineer - Distributed Systems
Foster City, California, United States
$242k-$333k/yr HybridFull Time
Zoox
Zoox: Develops autonomous electric vehicles for urban ride-hailing services.
6+ YOEDesign and develop distributed systems; strong C++/Python; AWS; Docker/Kubernetes; 6+ years experience; Bachelor's or higher in CS/Engineering.
C++, Python, Docker, Kubernetes, AWS, S3, EC2, Lambda, SQS, DynamoDB
3w
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Staff Full Stack Engineer, Platform DevXP
San Francisco or Seattle
$197k-$314k/yr HybridFull Time
Salesforce
SalesforceNYSE: CRM: Sells cloud-based customer relationship management and business software solutions.
7+ YOE7+ years web app and developer tooling experience; proficient in JavaScript, TypeScript, Python; API design; strong UX; team collaboration.
JavaScript, TypeScript, Python, APIs, Web development
3w
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Software Engineer
San Francisco, California, United States
RemoteFull Time
Whitespace
Whitespace: Building an agentic AI platform for geospatial and mission intelligence.
5+ YOE5+ years in software engineering; strong Java/Python, DevOps, SQL/NoSQL; experience in population simulation or data modeling; remote work acceptable.
Java, Python, GitLab, JIRA, Confluence, Jenkins, Nexus, SQL, NoSQL, Spark, Hadoop, BigQuery, Athena, EMR, AWS, Google Cloud, Azure
1mo
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AI Engineer
San Francisco, California, United States
$150k-$300k/yr OnsiteFull Time
Corridor
Corridor: Secures software codebases using AI-powered autonomous vulnerability detection.
2+ YOE2+ years in software engineering or ML; production-quality Python and backend experience; familiarity with AI research and deployment; interested in applied AI and security.
Python, ML frameworks, Backend systems, Vector stores, Hybrid search, Databases
1mo
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Software Engineer
San Francisco, California, United States
OnsiteFull Time
Applied Compute
Applied Compute: Developing custom AI agents and learning platforms for enterprises.
Strong full-stack engineering skills (React/TypeScript, Python); experience with real-time and asynchronous systems; capable of shipping production web apps.
React, TypeScript, Python, Temporal, Kubernetes, SSE, WebSockets, Airflow, SDKs, Dashboarding
1mo
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Product Engineer
Switzerland or Germany or United Kingdom or San Francisco or New York or Zurich
HybridFull Time
Namespace
Namespace: Cloud infrastructure platform for faster software builds and tests.
Strong software engineering fundamentals; experience with TypeScript/JavaScript (React), Go, Python; proven track record shipping features; customer-focused; collaborative.
TypeScript, JavaScript, React, Go, Python
1d
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Backend Engineer
San Francisco, California, United States
$190k-$230k/yr OnsiteFull Time
Lapel
Lapel: Unifying customer data to power personalized service at scale.
3+ YOE3+ years backend or software engineering; API design; backend architecture; Node.js/Python/Go; PostgreSQL/MySQL; scalable systems; customer-focused.
Node.js, Python, Go, PostgreSQL, MySQL, TypeScript, Temporal, Pulsar
1w
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Senior Software Engineer II
San Mateo or Ottawa
$126k-$158k/yr HybridFull Time
SurveyMonkey
SurveyMonkey: Provides online survey software and data collection tools.
8+ YOE8+ years ML development; AWS infrastructure; Python (Pandas/NumPy); NLP/LLMs; PySpark; Unix/Linux; real-time applications; Bachelor’s in CS/DS/SE/Math/Stats.
Python, Pandas, NumPy, PyTorch, transformers, AWS, Spark, PySpark, Unix/Linux
2mo
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Staff Software Engineer - Ouster SDK Team
San Francisco, California, United States
$180k-$220k/yr HybridFull Time
Ouster
OusterNASDAQ: OUST: Designs and manufactures digital lidar sensors for autonomous systems.
7+ YOE7+ years in high-performance C++ development; systems programming; Python; Open Source contribution; Linux expertise; cross-platform; OpenGL/Visualization; Docker; strong communication.
C++, Python, CMake, Pybind11, OpenGL, Docker, Linux, Git, CI/CD
2mo
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Senior Software Engineer, Enterprise Software Engineering
San Francisco, California, United States
$170k-$200k/yr OnsiteFull Time
Crusoe
Crusoe: Builds and operates sustainable data centers for AI workloads.
5+ YOE5+ years of production software experience; full-stack skills; AI-assisted development; strong in Python/TypeScript/Go; API integrations; cloud, containers, CI/CD.
Python, TypeScript, Go, APIs, Cloud platforms, CI/CD, Containerization
1w
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FSO LABS - AI Developer Senior - Bay Area (San Jose, CA, US, 95110)
San Jose, California, United States
$103k-$188k/yr HybridFull Time
EY
EY: Global firm providing audit, tax, and professional consulting services.
4+ YOE4+ years software development; SDLC experience; AI/automation focus; Azure cloud; Python and frontend tech; integration design; cross-functional work.
Azure, Python, JavaScript, TypeScript, Angular, React, Docker, Kubernetes, Power BI, Hadoop, Spark, Kafka, NoSQL, C++, C#, Java, SQL
2w
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Software Engineer
Mountain View, California, United States
$140k-$170k/yr OnsiteFull Time
CommerceIQ
CommerceIQ: AI-powered platform for e-commerce management and retail optimization.
2+ YOE2-5 years software engineering; Bachelor's in Computer Science; proficient in Java or Python; experience with AI tools; cloud services and CI/CD experience.
Java, Python, AWS, GCP, Azure, CI/CD, Microservices, GitHub, Claude

HiringCafe market data

Python Developer Jobs market signals in San Mateo, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
6,700+
Hiring companies
1,100+
Fresh sample
53% new in 30d
Salary visibility
80% show pay

Companies appearing in this market

AstreyaAttentiveCommerceIQCrusoeDiscordDocuSignEYJohnson & Johnson

Work location mix in visible results

Hybrid: 55Onsite: 54Remote: 11