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Python Engineer Jobs in Needham, MA, US

2,100+ python engineer jobs from 520+ companies hiring in Needham, MA, US.

2,165 jobs- Needham • 50 miles
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Senior Solutions Architect
Cambridge, Massachusetts, United States
$136k-$204k/yr HybridFull Time
HubSpot
HubSpotNYSE: HUBS: Provides a customer platform for marketing, sales, and service.
5+ YOE5+ years in solution architecture/technical consulting in SaaS; hands-on with LLM tooling and APIs; ability to map technical solutions to business value; strong cross-functional collaboration.
LLM tooling, APIs, Python, Node.js
1w
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Associate Director - Transmission & Distribution (T&D) Technical Services
San Antonio or Salt Lake City or New York or Boulder or Sacramento or Tampa or Boston or Folsom or Austin or Chicago or Houston or Denver or Phoenix or Los Angeles or Atlanta
$122k-$203k/yr OnsiteFull Time
Guidehouse
Guidehouse: Provides management and technology consulting services to diverse organizations.
7+ YOEUS Citizen or US Permanent Resident; advanced electrical/power systems degree; 7+ years utilities (or 5+ with Masters) or 3+ with PhD; power systems tools proficiency; willingness to travel; strong communication.
PSLF, POWERWORLD Simulator, PSSE, ASPEN, TARA, CAPE, DSATools, PSCAD, EMTP, Python, R, SQL
1mo
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Advanced Air Mobility & Unmanned Aerial Systems Technical Analyst
Burlington or Remote USA or Lake Oswego or New York or Anaheim or San Diego or Washington or Dallas
$55k-$175k/yr RemoteFull Time
Harris Miller Miller & Hanson
Harris Miller Miller & Hanson: Nationally recognized leader in environmental and technical consulting for infrastructure projects.
5+ YOEBachelor’s or Master’s in technical field; 5–10 years in AAM/UAM/UAS; acoustic modeling experience; strong writing/communication; travel up to 25%; US work authorization.
AEDT, Advanced Acoustic Model, NOISEMAP, MR_NMAP, ANOPP, Python, MATLAB, Excel, GIS
1w
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Scientist I - R&D Next Generation Sequencing
Westborough, Massachusetts, United States
$100k-$115k/yr OnsiteFull Time
Labcorp
LabcorpNYSE: LH: Provides clinical laboratory testing and drug development services globally.
1+ YOEPhD in Molecular Biology/Genetics/Biochemistry/Chemistry or Biomedical Engineering; 1+ years in molecular assays/NGS; 6+ months in R or Python.
Next Generation Sequencing, R, Python, Bioinformatics, Molecular Diagnostics
4w
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Technical Implementation Specialist
Boston, Massachusetts, United States
$70k-$100k/yr HybridFull Time
Paperless Parts
Paperless Parts: Cloud-based quoting software for custom part manufacturers.
Bachelor's degree in CS/Engineering/MIS or related field; strong Excel, Python, SQL; experience implementing customer solutions; travel up to 25%.
Excel, Python, SQL, P3L
1w
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Senior Manager-Artificial Intelligence- Global Development
Tarrytown or Armonk or Warren or Uxbridge
$148k-$242k/yr HybridFull Time
Regeneron
RegeneronNasdaq: REGN: Discovers and manufactures medicines for serious diseases.
AI/ML expert with generative AI, NLP, data engineering, Python/R, cloud infrastructure, and cross-functional collaboration; travel up to 20%.
Python, R, Cloud computing, NLP, Generative AI, SQL, Data engineering
1d
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Capgemini Invent / Cambridge Consultants - Engineering Co-op - Embedded Software (Burlington, MA, US)
Burlington, Massachusetts, United States
$20-$35/hr OnsiteInternship
Capgemini
CapgeminiEuronext Paris: CAP: Provides global IT consulting and digital transformation services.
0+ YOEPursuing BS or MS in electrical, computer engineering, computer science, or related fields; some software development experience; C/C++/Rust; MATLAB or Python; good testing and communication skills.
C, C++, Rust, MATLAB, Python
1mo
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Manager, Data Science (GenAI Solutions & ML Engineering) (Boston, MA, US, 02110)
Boston, Massachusetts, United States
$131k-$164k/yr OnsiteFull Time
XPO
XPONYSE: XPO: Provides less-than-truckload freight transportation and logistics services.
5+ YOE3+ MgmtBachelor’s degree; 5+ years in Machine Learning Engineering, Applied AI, or MLOps; 3+ years leading technical teams; strong end-to-end AI systems; Python and PyTorch; enterprise integration.
Python, PyTorch, ML frameworks
1w
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Associate AI Security Resident
Washington or San Francisco or Santa Monica or Pittsburgh or Boston
$90k-$177k/yr HybridFull Time
RAND
RAND: Provides research and analysis for public policy and security.
1+ YOETechnical security/engineering background; leadership experience; programming in Python/Java/C/C++; threat modeling; strong communication; policy analysis; collaboration; MS Office.
Python, Java, C/C++, Threat modeling, MS Office
4d
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Global Data Intern
Cambridge, Massachusetts, United States
$20-$25/hr HybridInternship
TriNetX
TriNetX: Global network providing real-world data for clinical research.
Internship in data engineering/operations; Python proficiency; strong analytical and collaboration skills; SQL/data processing familiarity; ability to meet deadlines in a fast-paced, hybrid environment.
Python, SQL, Databricks
3mo
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Post- Doctoral Research Associate
Providence, Rhode Island, United States
$58k-$96k/yr HybridFull Time
Brown University Health
Brown University Health: Provides regional academic healthcare and clinical research services.
3+ YOEPhD in computer science, pattern recognition, biomedical engineering, or related field; strong publication record; 3+ years research; grant writing preferred; Python and MATLAB required.
Python, MATLAB, Machine Learning
2w
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Director, Software Product Management & RE
Boston, Massachusetts, United States
$163k/yr OnsiteFull Time
Morgan Stanley
Morgan StanleyNYSE: MS: Provides global investment banking, wealth management, and advisory services.
3+ YOEMaster's degree in Engineering or Computer Science; 3 years in related role with AI, data, cloud, and DevOps skills; Snowflake, SQL, Python, Airflow, BI tools, and Agile experience.
Snowflake, SQL, Python, Airflow, DataDog, Splunk, Prometheus, Grafana, Autosys, Tableau, PowerBI, Git, Bitbucket, Terraform, BigPanda, APICA, Jira, ServiceNow, PagerDuty
1mo
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Staff Computational Biologist
Lexington or United States
$166k-$195k/yr HybridFull Time
Valo Health
Valo Health: Developing new medicines using an AI computational platform.
6+ YOE6+ years in computational biology/data-driven discovery; 1+ year in software/data engineering; Python and R; omics/translational analysis; ETL pipelines; product-owner experience.
Python, R, Omics data analysis, ETL pipelines
2mo
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Senior Catastrophe Modeling Analyst (Earthquake)
Boston, Massachusetts, United States
$118k-$135k/yr RemoteFull Time
Arch Capital Group
Arch Capital GroupNASDAQ: ACGL: Global provider of specialty insurance and reinsurance solutions.
5+ YOE5+ years catastrophe modeling; degree in seismology/earthquake/civil engineering; expertise in RMS/Verisk/KCC; SQL; Python or R; strong communication; able to work independently or in a team.
SQL, Python, R, ESRI/QGIS
2w
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Financial Advisory Senior AI Solution Architect (Nationwide, Remote)
New York or Denver or Georgia or Pennsylvania or Boston or Chicago or Houston or Dallas or Seattle or Detroit or New Jersey or California
$165k-$215k/yr RemoteFull Time
Huron
HuronNasdaq: HURN: Professional services firm providing management consulting and digital transformation.
8+ YOE8–12 years in software engineering/AI development; Python expert; experience with LLM APIs, document processing; cloud deployments (AWS/Azure); CI/CD; strong communication.
Python, LLM APIs, API development, PowerPoint, Excel, AWS, Azure, Git, Seismic, Salesforce, OpenSearch, SQL, python-pptx, openpyxl
3mo
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Analog Design Automation Intern
Toronto or Boston or Austin or Santa Clara
$35-$70/hr HybridInternship
Tenstorrent
Tenstorrent: Designs high-performance RISC-V CPUs and AI accelerator hardware.
Co-op or PEY student in Electrical Engineering with analog IC design exposure; Python proficiency; interest in ML concepts; open source tools; strong analytical and communication skills.
Python
3w
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Oliver Wyman - Senior Data Scientist
Boston or New York
HybridFull Time
Marsh McLennan
Marsh McLennanNYSE: MRSH: Provides global insurance brokerage, risk management, and professional consulting services.
Experience in data science, machine learning and AI, Python, model deployment, data engineering, and client-facing collaboration. Knowledge of generative AI is valued; cloud experience (Azure/AWS) preferred.
Python, Scikit-Learn, TensorFlow, PyTorch, MxNet, ONNX, LangChain, OpenAI, Anthropic, Strands Agents, Azure, AWS
6d
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PV and Energy Storage Remote Operator & Data Analyst
Westborough or Pine Brook
$34-$48/hr RemoteFull Time
Ameresco
AmerescoNYSE: AMRC: Develops and operates renewable energy and energy efficiency projects.
2+ YOEElectrical engineering degree or electrical license with 2+ years in solar operations and maintenance; proficient in Python, SQL, Excel; experience with PV and BESS; SCADA familiarity; strong data analysis and visualization skills.
Python, SQL, Excel, Power BI, Tableau, SCADA
2mo
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AI Technical Lead
Boston, Massachusetts, United States
$160k-$200k/yr HybridFull Time
IANS
IANS: Provides cybersecurity research and advisory services for security professionals.
5+ YOE2+ Mgmt5+ years AI/ML engineering; 2+ years in a senior/lead role; designed agentic AI systems; expert in LLMs, NLP, RAG; strong Python; APIs/SDKs; Azure; MLOps; leadership.
Python, PyTorch, TensorFlow, Hugging Face, LangChain, Azure, APIs, SDKs, Docker, Kubernetes
2mo
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Pre-Doctoral Research Associate
Providence, Rhode Island, United States
OnsiteFull Time
Brown University
Brown University: Private research university in Providence, Rhode Island.
Strong quantitative, programming, and data-analysis skills; background in economics, mathematics, statistics, computer science, or engineering; bachelor’s degree or equivalent with quantitative emphasis; experience with Python, Stata, R, MATLAB, SQL preferred.
Python, Stata, R, MATLAB, SQL
1mo
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Research Technician
Boston, Massachusetts, United States
$21-$28/hr OnsiteFull Time
Tufts University
Tufts University: Private research university providing higher education and academic research.
BS degree in science or engineering with familiarity and experience in mouse manipulation; knowledge of culturing bacteria, mesoscale/high-throughput measurements, data analysis; some Python or Matlab programming; strong attention to detail and teamwork.
Python, MATLAB, Statistics, MS Office, Bacteria culture, Mouse handling
1mo
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Vice President, Valuation and Analytics – Multiple Locations
Boston or Atlanta or New York or Chicago or Dallas
$145k-$225k/yr HybridFull Time
Houlihan Lokey
Houlihan LokeyNYSE: HLI: Global investment bank providing financial advisory and restructuring services.
6+ YOEBachelor’s and Master’s in Engineering, Math, Statistics or Physics; 6+ years client-facing; 4+ years managing Data Science/Analytics projects; expert Excel, VBA, Python, Snowflake, and a BI tool like Sigma or PowerBI.
Excel, Visual Basic, Python, Snowflake, Sigma, PowerBI
2mo
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US-E-GPS Consulting Services-Sr Data Scientist-AI&E/AI&D-PDM-638505
Boston, Massachusetts, United States
OnsiteFull Time
Deloitte
Deloitte: Provides professional audit, consulting, advisory, and tax services.
8+ YOEBachelor’s degree; 8+ years in data science/analysis/engineering; 5+ years Python and Databricks; 2+ years Medicaid/Medicare; ability to travel 10-15%; US work authorization; Public Trust clearance preferred.
Python, Databricks, SQL
3w
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Director / Senior Director, Computational & Protein Sciences
Cambridge, Massachusetts, United States
$250k-$290k/yr OnsiteFull Time
Stylus Medicine
Stylus Medicine: Develops in vivo genetic medicines with recombinases and nanoparticles.
10+ YOEPhD in computational biology or related field with 10+ years (or Master’s with 14+ years) of industry experience; strong protein modeling/engineering experience; AI/ML for protein design; expert Python/R; cloud and workflow experience.
Python, R, Pandas, NumPy, Bioconductor, SciPy, PyTorch, JAX, cloud computing, workflow management systems, AlphaFold2/3, RFdiffusion, ProteinMPNN, ESM
3mo
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Data Science Intern - Summer 2026 - Bedford, MA
Bedford, Massachusetts, United States
$40-$50/hr HybridInternship
AspenTech
AspenTech: Provides industrial software for optimizing asset performance and sustainability.
5+ YOEMaster’s in CS/Engineering/OR or related field; 5+ years data analysis and software development; Python, C/C++/C#; ML/AI experience; strong math/statistics; cloud/LLM a plus; US work authorized.
Python, C++, C#, C, Machine Learning, LLM, MLops, Cloud
3mo
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Senior Research & Sports Science Manager Footwear Innovation
Boston, Massachusetts, United States
$82k-$111k/yr OnsiteFull Time
PUMA
PUMAFrankfurt Stock Exchange: PUM: Sells athletic footwear, apparel, and sports accessories to global consumers.
5+ YOEMS or PhD in Kinesiology, Engineering, Biomechanics or related field; 5+ years footwear research; biomechanics, experimental design, statistics; experience with athletes; technical skills with biomechanical equipment; Matlab/Python/R; strong communication; willing to travel.
Matlab, Python, R, motion capture, force plates, metabolic cart, IMUs, pressure insoles
4w
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Postdoctoral Associate - The Getz Lab
Cambridge, Massachusetts, United States
$70k-$93k/yr OnsiteFull Time
Broad Institute
Broad Institute: Conducts genomic research to understand and treat human diseases.
0+ YOEPhD in bioinformatics/CS/ML/engineering/mathematics/statistics/physics or related field; 0-1+ years postdoc; computational analysis and statistics experience; spatial multi-omics data analysis; programming in Python/R/Matlab; strong communication; collaborative mindset.
Python, R, Matlab, Bioinformatics tools, Spatial multi-omics data analysis
1w
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Data Engineering Intern
Boston, Massachusetts, United States
RemoteInternship, Part Time
DomainTools
DomainTools: Provides DNS-based threat intelligence and domain investigation solutions.
Strong organization, attention to detail, clear communication; Python and Git experience; Spark/PySpark preferred; DNS/domain knowledge helpful.
Python, Git, Spark, PySpark
1mo
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Manager, Engineering
Raleigh or Chicago or Franklin or Boston
$148k-$175k/yr HybridFull Time
VitalSource
VitalSource: Provides digital course materials and e-learning software platforms.
5+ YOE5+ Mgmt5+ years of technical leadership; 5+ years in operations optimization; tests, reports, and documentation experience; strong Python, Django, PySpark, ETL, SQL skills.
Python, Django, PySpark, ETL, SQL
1mo
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Sr. Manager, Analytics Engineering & BI Architecture (Boston, Massachusetts, US, 02210)
Boston, Massachusetts, United States
$138k-$207k/yr OnsiteFull Time
Merck
MerckFrankfurt Stock Exchange: MRK: Global science and technology in healthcare, life science, and electronics.
5+ YOE5+ years in data warehousing/BI analytics; strong SQL; cloud data warehouses (Redshift/Snowflake); advanced Tableau development; Python or similar; excellent communication.
Tableau, Tableau Cloud, Amazon Redshift, Snowflake, AWS Glue, Python, SQL
3w
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Technical Marketing Manager
Nashua, New Hampshire, United States
OnsiteFull Time
Amphenol
AmphenolNYSE: APH: Designs and manufactures electrical connectors and interconnect systems.
Bachelor’s degree in engineering or related field; experience in applications/solutions engineering or technical marketing; familiarity with data center infrastructure and networking.
Python, Bash, Ansible, Ethernet, PCIe
1d
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AI Builder, Emerging Talent
San Francisco or Chicago or New York City or Burlington or Seattle or Bellevue or Atlanta
$110k-$133k/yr HybridFull Time
Salesforce
SalesforceNYSE: CRM: Provides cloud-based enterprise software for customer relationship management.
0+ YOEEarly-career engineer with strong CS/engineering foundation; proficient in AI/LLM concepts; capable of building production-ready AI solutions.
JavaScript, Python, Apex, React, TypeScript, GraphQL, OOP, Real-Time Infra
3w
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Solutions Consultant, Machine Learning
Boston, Massachusetts, United States
RemoteFull Time
Cradle
Cradle: Software platform for AI-guided discovery and optimization of proteins.
Graduate degree in ML/comp biology/CS; hands-on ML engineering; protein engineering familiarity; strong technical storytelling; travel 20-30%; remote role.
Python, Machine Learning, Data Pipelines, Bioinformatics tools
1mo
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Lead AI Solutions Architect - Full Stack
Princeton or Glen Allen or Coppell or Waltham or Philadelphia or Riverwoods or New York City or Chicago or Houston
$129k-$226k/yr HybridFull Time
Wolters Kluwer
Wolters KluwerEuronext Amsterdam: WKL: Provides professional information and software solutions for specialized industries.
10+ YOELeadership-focused AI solutions architect with 10+ years in full-stack engineering, GenAI/Agentic AI, data science, AI/ML, and applied AI engineering; proven leadership and mentoring experience.
Python, FastAPI, Angular, React, LangChain, LlamaIndex, SQL, NoSQL, Azure, AWS
1w
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Technical QA Lead
Boston, Massachusetts, United States
$112k-$154k/yr HybridFull Time
CD PROJEKT RED
CD PROJEKT REDWarsaw Stock Exchange: CDR: Develops high-quality story-driven role-playing video games.
5+ YOE2+ MgmtFive+ years in QA, with at least two years in a leadership role; strong testing methodologies and game engines knowledge; experience with Unreal Engine preferred; ability to design complex test strategies and collaborate cross-functionally.
Unreal Engine, Unity, Godot, PIX, Postman, C++, Python
1mo
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Associate Director, Media Analytics
Boston, Massachusetts, United States
$130k-$160k/yr HybridFull Time
Monks
MonksLondon Stock Exchange: SFOR: A global digital marketing and technology services agency
Senior analytics leader with hands-on data engineering and reporting experience; strong communication and client-facing skills.
SQL, ETL/ELT, Python, Databricks, Tableau, Datorama
1d
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AI Product Builder
Boston, Massachusetts, United States
HybridFull Time
Bisnow
Bisnow: Produces news and events for commercial real estate professionals.
1+ YOE1–3 years in product, engineering, data, or analytics; strong AI tooling, prototyping, and data pipeline experience.
Claude, Cursor, GPT, Git, AI prototyping, Python
1mo
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Network Manager/Architect
Somerville, Massachusetts, United States
OnsiteFull Time
oneZero Financial Systems
oneZero Financial Systems: Provides multi-asset trading technology for banks and brokerages.
10+ YOE5+ Mgmt10+ years in network architecture and management for trading infrastructure; strong automation with Ansible, Terraform; leadership of network engineering team.
Ansible, Terraform, Arista CloudVision, Cisco, Arista, Fortinet, VPN/ZTNA, Git, Napalm, Nornir, Spacelift, OpenTofu, DataDog, SolarWinds, SNMP, NetFlow, Python
1mo
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Integration Analyst
Northborough, Massachusetts, United States
$100k-$130k/yr OnsiteFull Time
Trelleborg
TrelleborgNasdaq Stockholm: TREL B: Develops engineered polymer solutions to seal, damp, and protect.
3+ YOEBachelor's in IT/CS/Engineering or equivalent experience; 3–5 years in enterprise system/data integrations; API/REST, JSON/XML; knowledge of iPaaS, middleware, or event-driven workflows; programming/scripting (Python/C#/Java/TypeScript/Node.js); cloud, containers, CI/CD beneficial.
REST, JSON, XML, OAuth 2.0, API Keys, PowerApps, Power Automate, CI/CD, containerization, cloud platforms
2mo
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Investment Agentic Workflow Strategist
Milwaukee or Charlotte or Boston
$135k-$175k/yr HybridFull Time
Allspring Global Investments
Allspring Global Investments: Provides global asset management and diversified investment advisory services.
Experience in investment processes with Bloomberg; AI-enabled workflow design; strong communication; bachelor's in finance, economics, engineering, CS, or related.
Python, BLPAPI, AI/ML tools

HiringCafe market data

Python Engineer Jobs market signals in Needham, MA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
2,100+
Hiring companies
520+
Fresh sample
45% new in 30d
Salary visibility
83% show pay

Companies appearing in this market

Tufts UniversityDeloitteMarsh McLennanMerckPaperless PartsWolters KluwerAllspring Global InvestmentsAmeresco

Work location mix in visible results

Hybrid: 21Onsite: 19Remote: 7