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Python Software Developer Jobs in Napa, CA, US

1,300+ python software developer jobs from 510+ companies hiring in Napa, CA, US.

1,340 jobs- Napa • 50 miles
2mo
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Machine Learning: Multimodal Foundation Models
San Francisco, California, United States
$200k-$350k/yr OnsiteFull Time
The Bot Company
The Bot Company: Developing AI-powered robots to automate household chores.
Production experience with large-scale multimodal models; strong Python/C++/Rust; experience training/deploying ML models; infrastructure for large GPU clusters.
Python, C++, Rust, PyTorch, CUDA
4d
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Infrastructure Engineer (GPU & Compute)
New York or San Francisco or Seattle
$180k-$200k/yr RemoteFull Time
Lightning AI
Lightning AI: Unified platform to build, train, and deploy AI models.
5+ YOE5+ years in infrastructure or systems engineering; strong Linux in production; GPU hardware and software experience; bare-metal provisioning; Python automation; debugging across hardware/OS/GPU.
NVIDIA DCGM, PXE, IPMI, Redfish, iDRAC, LiveCD, InfiniBand, NVLink, Linux, Python
1mo
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Advisory Analyst, Technology Transaction - Software: Experienced Consultant
Chicago or Boston or Dallas or Los Angeles or Minneapolis or New York or San Francisco or Seattle
$88k-$120k/yr HybridFull Time
West Monroe
West Monroe: Business and technology consultancy specializing in digital transformation.
2+ YOEBachelor’s degree or equivalent; 2-4+ years software development experience; strong SDLC, OO design (C#, Java, Python); Agile/Lean; ability to lead requirements; travel 20-30%; hybrid in US offices; authorized to work in the US without sponsorship
C#, Java, Python, SDLC, Agile, Agentic AI/LLMs
3mo
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Robotics Test Engineer
San Francisco, California, United States
OnsiteFull Time
Pronto: Develops autonomous haulage systems for mining and industrial vehicles.
3+ YOE3+ years in software testing/QA/automation; strong Python; test frameworks; automation infra; CI/CD; excellent cross-team communication; log data debugging.
Python, pytest, unittest, Docker, GitHub Actions
3w
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Senior Controls Engineer
San Francisco, California, United States
$115k-$170k/yr OnsiteFull Time
Marathon Fusion
Marathon Fusion: Developing fuel processing technologies for commercial fusion power plants.
3+ YOE3+ years in industrial control systems; PLC-based control and instrumentation; experience with LabVIEW, Python; DAQ knowledge; able to design, debug hardware and software control systems.
LabVIEW, Python, PLC, DAQ
2mo
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Geospatial Data Engineer
San Francisco, California, United States
$133k-$202k/yr HybridFull Time
Pano AI
Pano AI: AI-powered wildfire detection and real-time intelligence platform.
3+ YOE3+ years software engineering; BS in Computer Science or equivalent; 2+ years Python; 2+ years building data systems on cloud; 2+ years with relational databases (PostgreSQL).
Python, Google Cloud, Kubernetes, CI/CD, PostgreSQL, Cloud
1w
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Senior R&D Engineer, Lab Automation Applications Engineer
San Francisco, California, United States
$190k-$262k/yr HybridFull Time
Chan Zuckerberg Biohub
Chan Zuckerberg Biohub: Builds AI-powered technologies for biomedical research and disease study.
5+ YOE5+ years in laboratory automation; experience with Hamilton STAR/Vantage, VENUS software; programming in Python; knowledge of cell biology and molecular biology; strong documentation and project management skills.
Hamilton STAR, Hamilton Vantage, VENUS, OpenTrons, Agilent Bravos, Python
3w
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Staff Electrical Engineer – FPGA / MPSoC Systems & Digital Signal Processing
San Leandro, California, United States
$160k-$180k/yr OnsiteFull Time
SirenOpt
SirenOpt: Provides real-time, non-destructive material characterization for advanced manufacturing.
5+ YOE5+ years in FPGA/MPSoC design, DSP, MATLAB/Python, HDL/RTL, and board bring-up; strong hardware-software integration.
MATLAB, Python, HDL/RTL, FPGA, MPSoC, DSP, Oscilloscopes, Logic Analyzers, Schematic Reading, Bench Testing
3w
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Senior Staff Quality Engineer - S3
San Francisco, California, United States
RemoteFull Time
DataDirect Networks
DataDirect Networks: Provides high-performance data storage and management solutions for AI.
12+ YOE12+ years in systems software quality engineering; strong C/C++, Python/shell scripting; Linux file system testing; test strategy ownership and leadership.
C/C++, Python, Shell, gcc, gdb, g++, git, Linux
1mo
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Investment Data & Analytics Engineer- Vanguard Personalized Indexing
Oakland, California, United States
$90k-$150k/yr OnsiteFull Time
Vanguard
Vanguard: Provides mutual funds, ETFs, and investment management services.
3+ YOE3+ years in software/data/analytics engineering; Python proficiency; AWS; data lakes/pipelines; investments domain exposure; team contributor.
Python, AWS, Plotly Dash
1w
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Platform Engineer
San Francisco, California, United States
OnsiteFull Time
Axiom
Axiom: Uses AI to predict drug toxicity, replacing animal testing.
Strong generalist software engineer with experience building production backend, distributed systems, ML infrastructure, and enterprise SaaS for large enterprise customers.
Python, TypeScript, Go, Rust, Kubernetes, Docker, Terraform, Pulumi, CI/CD, Ray, Modal, Slurm, Anyscale, Spark, Dask, Daft, Airflow, Dagster, Prefect, Argo, Postgres, DuckDB, Snowflake, BigQuery, ClickHouse, Elasticsearch, OpenSearch, vector databases, LLM systems
2mo
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Senior Image Quality Engineer
Dublin, California, United States
$140k-$175k/yr HybridFull Time
ZEISS
ZEISS: A leading technology enterprise specializing in optics and optoelectronics.
3+ YOE3-7 years in X-ray/CT imaging or related imaging; degree in Engineering/Physics; strong IQ metrics, processing, and reconstruction know-how; proficient in Python/Matlab; experience with CT concepts and CT-related software.
Python, Matlab, CT imaging, image processing, reconstruction algorithms
3w
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Field Team - Member of Technical Staff
San Francisco, California, United States
$200k-$325k/yr HybridFull Time
Goodfire
Goodfire: Developing tools to interpret and steer artificial intelligence systems.
Strong software engineering in Python and ML frameworks (PyTorch, JAX); cross-domain collaboration; fast learner; strong communication.
Python, PyTorch, JAX
3mo
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Staff AI/ML Platform Engineer
Oakland or United States
HybridFull Time
Albert Invent
Albert Invent: Cloud platform accelerating chemistry and materials science research.
5+ YOE7+ years in software engineering; advanced Python; REST APIs; data pipelines; workflow orchestration; cloud and containers; experience with Ray/Temporal; SQL/NoSQL data stores.
Python, FastAPI, REST API, Ray, Temporal, AWS, Docker, Kubernetes, Neptune, Redis, DynamoDB, Grafana, Prometheus, Datadog, GPU, Graph databases
3w
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88-50100015 Machine Learning Engineer
South San Francisco, California, United States
$191k-$249k/yr HybridFull Time
Roche
RocheSIX Swiss Exchange: ROG: Develops and manufactures innovative medicines and diagnostic tests.
2+ YOEMaster’s degree in Computer Science or Biomedical Imaging (or foreign equivalent); 2 years ML/DS/Software ML experience; Python; cloud (Azure/AWS); data engineering; ML model deployment; biomedical imaging and multi-modal data familiarity.
Python, Azure, AWS, Databases, Machine Learning, Cloud Platforms, Large Language Models
1mo
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Product Security Engineer
Canada or New York or San Francisco or United States
$94k-$125k/yr RemoteFull Time
Lattice
Lattice: Software platform for employee performance, engagement, and talent management.
1+ YOE1–3+ years in product security or software engineering; JavaScript/TypeScript (or Python/Ruby); OWASP Top 10 familiarity; security testing tools (SAST/DAST); cloud experience (AWS).
SAST, DAST, Dependency Scanning, AWS
1mo
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Tech Lead - Growth
San Francisco, California, United States
OnsiteFull Time
Arcade
Arcade: Infrastructure for AI agents to securely interact with external applications.
7+ YOE1+ Mgmt7+ years software engineering with technical leadership; strong backend and systems experience; Go/Python; React; leading small teams; growth mindset.
Go, Python, TypeScript, React, PostgreSQL
4w
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Senior Systems Verification & Validation Engineer
San Francisco, California, United States
$165k-$195k/yr OnsiteFull Time
Serve Robotics
Serve RoboticsNasdaq: SERV: Autonomous sidewalk robots for sustainable last-mile urban delivery.
8+ YOE8+ years in design and test of complex electromechanical/robotic systems; BS in Mechanical/Electrical/Software; hands-on test infrastructure; Python/SQL; data analysis; V&V methods; cross-functional collaboration.
Python, SQL, Unix/Linux
1w
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AI Agent Infrastructure Lead
San Francisco, California, United States
$230k-$260k/yr OnsiteFull Time
Sphere
Sphere: AI-powered global tax compliance and automated filing software.
Experience building production software; AI agents or internal developer tooling; backend systems; safety and autonomy; strong initiative and attention to detail.
Python, CI/CD, Infrastructure
2mo
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Senior Solutions Engineer
San Francisco, California, United States
$193k-$241k/yr OnsiteFull Time
Box
BoxNYSE: BOX: Cloud content management and collaboration platform for global enterprises.
5+ YOE5+ years pre-sales/solutions engineering in SaaS/enterprise software; AI-curious; strong presentation skills; experience with APIs and modern architectures.
REST, OAuth, JSON, Python, JavaScript, APIs, Nintex, Zapier, Workato, n8n
2mo
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Entry-Level Structural Engineer | Designer
San Francisco or Los Angeles or Sacramento or San Diego or Detroit or Grand Rapids or Orange
$84k-$112k/yr HybridFull Time
Degenkolb Engineers
Degenkolb Engineers: Specializes in structural engineering and earthquake-resistant building design
1+ YOEMS in Structural Engineering or BS in Civil Engineering with 1-2 years experience; GPA 3.40+; authorized to work in the United States; software proficiency expected.
AutoCAD, Tekla, RISA, RAM, Revit, Excel, MathCAD, SAP2000, ETABS, Python
2mo
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Sales Engineer - Enterprise, TOLA
Denver or San Francisco or Phoenix or Seattle
$1-$2/yr RemoteFull Time
Samsara
SamsaraNYSE: IOT: Sells sensors and software for fleet and industrial monitoring.
5+ YOEBS degree; 5 years in pre-sales or customer-facing roles; ability to explain technical concepts to non-technical audiences; hardware/software evaluations; basic electronics; open APIs; strong growth mindset.
Open API, Cloud software, Cloud-connected hardware, Bash, Python, JavaScript
1mo
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Payer Dev, Git & ML-Ops Engineer, Senior Associate
Boston or Indianapolis or Raleigh or Charlotte or Jacksonville or Chicago or Cincinnati or Cleveland or Columbia or Kansas City or Columbus or Dallas or Las Vegas or Los Angeles or Baltimore or Birmingham or St. Louis or Salt Lake City or San Diego or San Francisco or Silicon Valley or Seattle or Stamford or Tampa or Toledo or Austin or Washington or New York or Florham Park or Philadelphia or Phoenix or Pittsburgh or Houston
$77k-$202k/yr OnsiteFull Time
PwC
PwC: Providing audit, tax, and management consulting services to businesses.
4+ YOEBachelor's degree; 4+ years software or data engineering; experience with dbt on Databricks; healthcare analytics experience; CI/CD pipelines for Databricks; Azure Databricks workspace provisioning; Python CLI tools.
Databricks, dbt, Azure Databricks, Python, YAML, argparse, CI/CD, AI agent systems
2mo
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Client Engineer III (MedInsight)
Seattle or Appleton or Atlanta or Boise or Wakefield or Chicago or Dallas or Hartford or Omaha or San Francisco or Portland or Portland
$85k-$162k/yr RemoteFull Time
Milliman
Milliman: Provides actuarial consulting and risk management solutions globally.
5+ YOE5+ years in analytics/data engineering with client-facing delivery; expert SQL; dimensional modeling; strong software engineering practices; able to lead data-driven implementations.
SQL, Git, CI/CD, ETL, Data Modeling, Python, Cloud
3w
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Junior Coastal Engineer
San Francisco or Oakland or Sacramento or Petaluma
$85k-$100k/yr HybridFull Time
Environmental Science Associates
Environmental Science Associates: Provides environmental consulting for infrastructure and restoration projects.
0+ YOEBachelor’s in Civil/Environmental Engineering or related field; 0-3 years’ experience; EIT or ability to obtain within 1 year; coastal/restoration experience desirable; proficiency in design/modeling software preferred; strong communication; ability to work in hybrid office settings.
AutoCAD Civil 3D, ArcGIS, HEC RAS, HEC HMS, XBeach, SWAN, MATLAB, Python
3w
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Forward Deployed AI Engineer
San Francisco, California, United States
HybridFull Time
Latent Labs
Latent Labs: Building generative AI models to make biology programmable.
Strong CS/ML background; experience deploying AI systems; cloud infrastructure; customer-facing; production software; pharma/biotech domain knowledge.
AWS, GCP, Azure, Docker, Kubernetes, CI/CD, Cloud-native, APIs, Python, ML frameworks
1w
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Field Solutions Engineer, Spacetime Integrations
United States or San Francisco
$160k-$215k/yr RemoteFull Time
Aalyria
Aalyria: Provides laser communications and networking platforms for aerospace.
4+ YOE4+ years in customer-facing technical roles; bachelor's in CS/Engineering; strong software dev; experience with APIs; Linux, containers/Kubernetes; export controls awareness.
Go, Python, Java, C++, Linux, Docker, Kubernetes, CI/CD, gRPC, protobuf
1d
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Agentic-Workflow MLE (Pipeline)
San Francisco, California, United States
$250k-$350k/yr HybridFull Time
Prophecy
Prophecy: AI-native platform for building and automating enterprise data pipelines.
6+ YOE6+ years software engineering; 2+ years AI/ML; hands-on LLM/agent building; semantic search, RAG, vector databases; prompt engineering; Python, REST APIs, microservices; Go, AWS, k8s, Java, Scala; experience with Knowledge Graphs and multi-agent systems.
Python, REST APIs, microservices, Go, AWS, Kubernetes, Java, Scala, LangChain, Weaviate, Pinecone, Neo4j, Neptune, GitHub Copilot, Codex
2mo
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HNP Rebele Editorial AI Development Intern
San Francisco, California, United States
$9k/hr OnsiteFull Time
Hearst Television
Hearst Television: Operates local television and radio stations across the United States.
Internship in AI/engineering with Python, APIs, REST/JSON, Git; newsroom tools; collaboration; fast-paced deadlines.
Python, REST, JSON, Git, AWS, S3, EC2, Lambda, Github Copilot, Cursor, Slack, Zoom, Google Sheets
2w
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Senior Security Engineer, Detection and Response
Austin or San Francisco or Seattle or Boston or Washington
$182k-$202k/yr RemoteFull Time
HackerOne
HackerOne: Connecting organizations with ethical hackers to find security vulnerabilities.
5+ YOE5+ years in detection and response or security engineering; strong software fundamentals; experience with cloud (AWS); experience with log analysis and endpoint detection tools.
Python, Go, Ruby, CloudTrail, GuardDuty, VPC flow logs, Datadog, Splunk, ELK, SentinelOne, CrowdStrike
2w
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Senior, Advanced Application Engineer - Location Flexible (Oakland, CA, US, 94612)
Oakland, California, United States
$116k-$194k/yr HybridFull Time
PG&E
PG&ENYSE: PCG: Provides natural gas and electric service in California.
5+ YOEBachelor's in engineering; 5 years electric utility experience; experience with grid modeling software (e.g., CYMDIST, PSLF, Aspen).
Python, C#, SQL, Jira, MS Excel, Foundry, Power BI, CYMDIST, PSLF, Aspen
1mo
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Member of Technical Staff - Compilers
San Francisco, California, United States
$150k-$350k/yr OnsiteFull Time
Gimlet Labs
Gimlet Labs: Optimizing AI inference performance across diverse hardware architectures.
Strong software engineering fundamentals; experience with compiler systems; ability to optimize across hardware boundaries.
C++, Python, LLVM, MLIR, TVM, XLA, GPU lowering
2mo
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Junior Geospatial Data Scientist (Pipeline & Algorithm Focus)
San Francisco, California, United States
OnsiteFull Time
Matter Intelligence
Matter Intelligence: Develops hyperspectral sensors and AI for advanced Earth observation.
BS or MS in a quantitative field; hands-on hyperspectral data experience; strong Python; remote sensing physics knowledge; pipeline and production coding.
Python, GDAL, Rasterio, Xarray, NumPy, SciPy, ENVI, GeoTIFF, NetCDF/HDF
2w
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Ex-Founder
San Francisco, California, United States
OnsiteFull Time
Wispr Flow
Wispr Flow: Provides AI-powered voice dictation software for computers and mobile devices.
Former founder with engineering or growth expertise; for engineers: proficient in TypeScript, React, Python; for growth: scalable growth experience and user-centric mindset.
TypeScript, React, Python
3w
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AI/ML Intern
Arizona or California or Colorado or North Carolina or San Francisco or Utah
$40-$50/hr RemoteInternship
Rocket Lawyer
Rocket Lawyer: Provides online legal document creation and attorney consultation services.
Pursuing BS, MS, or PhD in CS/Math/Stats; basic ML concepts; familiarity with generative AI; interest in LLMs; strong Python.
Python, FastAPI, Flask, Django, TensorFlow, PyTorch
1w
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Member of Technical Staff - AI Product
San Francisco, California, United States
OnsiteFull Time
Eigen: Building an AI-driven social agent as the internet's shared friend.
Experience designing large, maintainable AI systems; autonomous problem solving; strong product sense; experience with Typescript, Python; building agentic systems.
Typescript, Python, Agentic systems
3w
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Member of Technical Staff - Security
San Francisco or New York City
RemoteFull Time
Runlayer
Runlayer: Security and governance platform for enterprise AI agents.
8+ YOE8+ years in security engineering with emphasis on application security and endpoint detection; Python/FastAPI; experience with enterprise security and API/gateway attack patterns.
Python, FastAPI
4w
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Intern, AI Engineering
South San Francisco, California, United States
OnsiteFull Time, Internship
Denali Therapeutics
Denali TherapeuticsNASDAQ: DNLI: Developing therapies to treat neurodegenerative and lysosomal storage diseases.
Pursuing Master’s or Ph.D. in CS/AI/ML; strong Python and NLP skills; experienced with LLMs, prompt engineering, RAG; able to collaborate with experts; good communication and documentation.
Python, LLM APIs, Hugging Face, NLP, Git, XML, JSON
2w
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Founding Forward Deployed Machine Learning Engineer
San Francisco or Bay Area
HybridFull Time
Adaption
Adaption: Develops efficient AI systems that adapt in real-time.
4+ YOE4+ years industry, 2+ years in customer-facing tech role; strong software engineering; familiarity with ML frameworks; data modeling for training; experience with human feedback/adaptive learning; excellent communication; ownership mindset.
Python, PyTorch, JAX, TensorFlow
1mo
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Member of Technical Staff - Applied ML, RecSys
San Francisco or Boston or Remote
HybridFull Time
Liquid AI
Liquid AI: Develops efficient general-purpose artificial intelligence foundation models.
Hands-on experience building or fine-tuning recommendation models at scale; sequential recommendation architectures; data quality and evaluation design; large-scale data pipelines; Python and PyTorch proficiency.
Python, PyTorch, Large-scale data pipelines, Recommendation models

HiringCafe market data

Python Software Developer Jobs market signals in Napa, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
1,300+
Hiring companies
510+
Fresh sample
48% new in 30d
Salary visibility
67% show pay

Companies appearing in this market

West MonroeBoxDegenkolb EngineersGimlet LabsLiquid AIThe Bot CompanyAalyriaAdaption

Work location mix in visible results

Hybrid: 20Onsite: 19Remote: 9