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Senior Director Medical Affairs Jobs in California, United States
100+ senior director medical affairs jobs from 59 companies hiring in California, United States.
1mo
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Senior Director, Medical Affairs, Neurology/CNS
United States
$275k-$335k/yr RemoteFull Time
10+ YOE3+ MgmtMD/DO/PharmD/PhD with 10+ years in Medical Affairs in biotech/pharma; leadership at director level; strong KOL networks; experience with advisory panels and US Medical Affairs regulations.
1mo
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Director, Medical Affairs Research
Foster City, California, United States
$243k-$315k/yr HybridFull Time
10+ YOESenior Director-level role leading oncology Medical Affairs research with expertise in interventional, real-world evidence, or implementation science.
2w
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Medical Director, Medical Affairs (Endocrine-Oncology) (Senior Director-Executive Director Level)
Redwood City or United States
$250k-$290k/yr HybridFull Time
7+ YOEMD/DO or equivalent; senior Medical Affairs leadership in oncology/endocrinology; rare-disease experience; travel up to 50%; MLR/Medical Information experience preferred.
2mo
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Executive Director, Medical Affairs
United States
$325k-$375k/yr RemoteFull Time
12+ YOE5+ MgmtPhD or equivalent with 12+ years in medical affairs/clinical research; 5+ years leading Medical Affairs.
1mo
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Director, Medical Affairs (Cardiometabolic)
Pasadena, California, United States
$230k-$260k/yr OnsiteFull Time
5+ YOEPhD or PharmD in life sciences; 5+ years in Medical Affairs; cross-functional collaboration; strong project management and communication; ability to manage multiple projects.
4w
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Associate Medical Affairs Director
San Diego, California, United States
$174k-$237k/yr OnsiteFull Time
7+ YOEMD/PhD/PharmD with 7+ years in Medical Affairs or related pharmaceutical consulting; strong leadership, communication, and regulatory knowledge.
1mo
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Senior Director, Medical Affairs
San Diego, California, United States
$300k-$350k/yr OnsiteFull Time
MD required; biotech/pharma experience; rare disease/cell therapy familiarity; travel 30-40%; strong communication and regulatory knowledge.
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Director, Medical Affairs Research
Foster City, California, United States
$243k-$315k/yr HybridFull Time
10+ YOEAdvanced scientific/medical degree with ~10+ years in oncology research or medical affairs; leads late-phase oncology research; strong leadership and cross-functional collaboration; ensures regulatory compliance.
3d
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Assoc Director, Medical Affairs
Santa Monica or Foster City or Parsippany
$178k-$230k/yr OnsiteFull Time
10+ YOE10+ years BS; 8+ years MS; 5+ years PhD/PharmD; 2+ years MD; oncology/Medical Affairs experience; cross-functional collaboration; travel ~35%
3d
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Scientific Director / Medical Director, Medical Affairs – Oncology
Irvine or Mettawa or Florham Park or San Francisco
$161k-$305k/yr HybridFull Time
5+ YOE1+ MgmtDirector-level Medical Affairs role requiring advanced degree and 5-7+ years in pharma; Oncology focus preferred.
4d
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Associate Director, Medical Affairs
United States
$180k-$280k/yr RemoteFull Time
5+ YOEPharmD, Ph.D., or MD required; 5+ years Medical Affairs experience; 3+ years as content reviewer (MLR); regulatory and quality assurance knowledge; experience in rare neuromuscular diseases; strong prioritization and communication skills; 20% travel.
3w
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Director, Field Medical Affairs (Neurology)
United States
$205k-$342k/yr RemoteFull Time
10+ YOE5+ MgmtAdvanced medical/scientific degree with 10+ years in Medical Affairs; prior MSL leadership; neurology experience preferred; proficiency in Word, Excel, PowerPoint, and Veeva.
Veeva, Microsoft Word, Microsoft Excel, Microsoft PowerPoint
2mo
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Senior Director, Medical Affairs - Respiratory
United States
$273k-$372k/yr RemoteFull Time
8+ YOEMD required with pulmonology experience; 8+ years in pharma/biotech; medical affairs leadership; launch experience.
3w
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Associate Director, Medical Affairs (West Coast)
Los Angeles, California, United States
$160k-$200k/yr RemoteFull Time
5+ YOEMedical affairs leadership in pharma; 5+ years field-based medical experience; rare disease/neurology/pediatrics preferred; advanced degree preferred; valid driver’s license.
Medical Affairs software, CRM
1w
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Director, Medical Affairs Strategy & Education
Irvine, California, United States
$203k-$285k/yr HybridFull Time
10+ YOE5+ MgmtAdvanced degree required; 10+ years in medical affairs/eye care; leadership experience; strong communication; regulatory knowledge preferred.
2mo
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Director, Field Medical Affairs - Remote Position
Los Angeles, California, United States
$250k-$270k/yr RemoteFull Time
6+ YOE1+ MgmtSix+ years in Medical Affairs with oncology experience; strong leadership of MSL teams; Doctorate preferred; excellent communication and strategic planning.
Microsoft Office, CRM systems, Medical databases
3w
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Catalyst Pharmaceuticals, Inc - Senior Medical Director, Medical Affairs - aGAMREE
United States
$330k-$373k/yr RemoteFull Time
5+ YOE5+ MgmtMD required; 5-10 years clinical/medical affairs; leads MSL team; 60% travel; preferably neuromuscular/rare disease experience.
MS Word, PowerPoint, Excel, Medical Affairs tools
5d
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Regional Field Director, Medical Affairs
United States
$200k-$220k/yr RemoteFull Time
3+ YOE3+ years as an MSL; strong leadership in Medical Affairs; prior MSL management; excellent communication; cross-functional leadership; proficiency with MS Office; experience with tracking/logging software.
PowerPoint, Word, Excel
1w
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Director, Medical Affairs Strategy & Education
Irvine, California, United States
$203k-$285k/yr HybridFull Time
10+ YOE5+ MgmtAdvanced degree (OD/PhD/PharmD); 10+ years in medical affairs/eye care; leadership in KOL engagement, education strategy, and congress planning; regulatory knowledge; travel up to 40%.
1mo
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Regional Director, Field Medical Affairs - East
United States
$250k-$280k/yr RemoteFull Time
7+ YOE5+ MgmtAdvanced scientific degree with 7+ years Medical Affairs and 5+ years field medical; MSL leadership; dermatology experience; strong communication; up to 75% travel.
2mo
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Senior Director, US Medical Affairs
South San Francisco, California, United States
$233k-$280k/yr HybridFull Time
12+ YOEMD, PhD, PharmD or MD/PhD; 10–12 years in Medical Affairs with 3–5 years in Phase 1–3 development; US pre-commercial planning; payer/reimbursement expertise; gene therapy/Neuroscience experience; FDA/OIG knowledge; startup leadership; travel up to 40%.
1mo
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Sr Director, Medical Affairs
San Diego or Milpitas
$200k-$359k/yr HybridFull Time
10+ YOE5+ MgmtSenior leadership role overseeing Medical Affairs/Clinical Affairs; 10+ years in regulated healthcare/diagnostic environment; MD/MD-PhD with Hematopathology background preferred; strong clinical trials and lab management experience.
Flow Cytometry, Laboratory Management, Clinical Trials, Regulatory Knowledge, Medical Affairs, Hematopathology, CLSI Guidelines, FDA Regulations
2mo
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Director, Medical Affairs (Pathology/Oncology)
San Diego, California, United States
$225k-$337k/yr OnsiteFull Time
10+ YOE8+ MgmtBoard-certified molecular pathologist with 10+ years CLIA/CAP experience; 8+ years leadership in molecular pathology; 5+ years developing molecular diagnostics for cancer.
Next-Generation Sequencing, Bioinformatics, Molecular Diagnostics, Karyotyping, FISH, MSI Analysis
3w
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Senior Director, US Medical Affairs Strategy Lead - Lung
United States
$232k-$290k/yr RemoteFull Time
15+ YOEAdvanced doctorate; 15+ years in biotech/pharma Medical Affairs; strong lung cancer biomarker expertise; clinical trial support; leadership; travel 30-40%.
Microsoft Office, Data analysis
1w
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Executive Director Global Medical Affairs, Hematology
United States
$297k-$377k/yr RemoteFull Time
8+ YOEAdvanced scientific degree with 8+ years in pharma; hematology/oncology expertise; global medical affairs leadership; launch experience; budget and cross-functional collaboration; travel up to 25%.
5d
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Regional Field Director, Medical Affairs
United States
RemoteTemporary, Full Time
3+ YOELead and manage MSL teams, drive regional medical plans, and mentor staff; strong leadership and scientific engagement required.
PowerPoint, Word, Excel
3d
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Medical Director, CRM Medical Affairs
Sylmar, California, United States
$219k-$437k/yr OnsiteFull Time
10+ YOEMD or DO with board certification in Clinical Cardiac Electrophysiology; 10+ years in cardiac rhythm management; strong leadership and medical communications.
2w
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Director, Scientific Affairs
Foster City, California, United States
$235k-$250k/yr HybridFull Time
5+ YOESeeking an advanced science/clinical degree holder with 5+ years in medical affairs or clinical/scientific research; rare disease expertise; strong publication and data analysis skills.
SAS, R, Excel, PowerPoint, Word
3d
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Medical Director, CRM Medical Affairs
Sylmar, California, United States
$219k-$437k/yr OnsiteFull Time
10+ YOEMD/DO with board certification in Clinical Cardiac Electrophysiology; 10+ years in cardiac rhythm management; device therapy knowledge; medical monitoring; leadership in clinical events; strong communication.
1w
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Executive Director, Medical Affairs
United States
$279k-$363k/yr RemoteFull Time
10+ YOEMD or PharmD with cardiovascular expertise; 10+ years biopharma; leadership in medical affairs; product launch experience preferred.
2mo
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Regulatory Affairs Director
Santa Clarita, California, United States
$150k-$200k/yr HybridFull Time
10+ YOEBachelor's degree; 10+ years in medical device regulatory affairs; experience obtaining regulatory approvals including clinical trials; strong communication and project management skills; experience with SaMD and Digital Health apps; hands-on, startup-like environment experience.
2mo
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Director, Clinical Operations & Medical Affairs, Data & Analytics
San Diego, California, United States
$208k-$252k/yr OnsiteFull Time
10+ YOE10+ years biotech/pharma with 5+ years in data analytics for medical affairs/clinical operations; strong BI, SQL/R/Python; experience with trial systems and CRO data ingestion.
CTMS, EDC, IRT/RTSM, Veeva Medical/CRM, Tableau, Power BI, Looker, SQL, R, Python
2w
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Area Director, Field Medical Affairs (East)
United States
$250k-$295k/yr RemoteFull Time
15+ YOE10+ MgmtAdvanced scientific/clinical degree; 15+ years biopharma; 10+ years leading MSLs; 50%+ travel; strong leadership and strategic skills.
CRM
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Senior Medical Director, Medical Affairs Asset Lead
United States
$300k-$366k/yr RemoteFull Time
13+ YOE10+ MgmtMD/DO/PhD/PharmD (or equivalent) with 13+ years MA experience; 5+ years leadership in pharma; 10+ years in supervision; endocrinology/rare disease experience preferred.
Veeva, Promomats, MedComm, MSL, CRM, ARISg, Argus
1w
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(Sr) Medical Affairs Scientific Director (Home Office, US)
United States
$200k-$275k/yr RemoteFull Time
8+ YOEMD with 8+ years in Pulmonology/Critical Care; US travel 15-20%; RTP, NC or remote; board certification preferred.
1w
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Medical Affairs Executive Director (MED) - Arizona / New Mexico
Arizona or New Mexico or South San Francisco
$206k-$382k/yr HybridFull Time
10+ YOEAdvanced clinical science degree; 10+ years related experience; strategic, cross-functional leadership; strong stakeholder engagement and field leadership.
1mo
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Associate Director/Manager, Field Medical Affairs
Seal Beach, California, United States
$146k-$215k/yr OnsiteFull Time
10+ YOE3+ MgmtAdvanced scientific or clinical degree; 10+ years pharma/life sciences experience; 5+ years as MSL with 3+ in leadership; proven leadership and field strategy execution; oncology/immuno-oncology exposure.
2mo
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Director, Scientific Affairs (Hematology)
United States
RemoteFull Time
3+ YOEAdvanced life sciences degree preferred; 3+ years hematology and medical education experience; strong scientific content development and communication skills; willingness to travel.
PowerPoint, Microsoft Office
3w
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Health Systems Medical Affairs Director - PA, NJ, DE
North Wales or United States
$191k-$300k/yr RemoteFull Time
3+ YOEMD/PhD/PharmD; 3 years field-based payer/provider experience or 5 years health-system clinical experience; healthcare system/payer relationship skills; strong clinical and policy knowledge; excellent communication and leadership.
1mo
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Director of Training, Global Medical Affairs
United States
$210k-$245k/yr RemoteFull Time
10+ YOE5+ MgmtAdvanced degree; 10+ years biotech/pharma; 5+ years Medical Affairs leadership; cell/gene therapy experience; regulatory/compliance knowledge; strong cross-functional leadership.
Training content development tools, LMS, Slides/Presentation tools
HiringCafe market data
Senior Director Medical Affairs Jobs market signals in California, United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
100+
Hiring companies
59
Fresh sample
50% new in 30d
Salary visibility
96% show pay
Companies appearing in this market
Gilead SciencesAbbottAbbVieBeOne MedicinesBridgeBio PharmaRegeneronRevolution MedicinesTarsus Pharmaceuticals
Work location mix in visible results
Remote: 39Hybrid: 20Onsite: 11
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