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Senior Python Software Engineer Jobs in Frederick, CO, US
360+ senior python software engineer jobs from 130+ companies hiring in Frederick, CO, US.
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Sr Staff / Senior Python Software Engineer
Boulder, Colorado, United States
$126k-$175k/yr OnsiteFull Time
6+ YOEBachelor’s degree in CS/Engineering/Math/Physical Sciences; 6+ years of professional Python software engineering; microservices and distributed systems; real-time data processing pipelines; automated testing; Linux; Git; DoD clearance; strong communication.
Python, Linux, Docker, Git, pytest, CI/CD, Microservices, Distributed Systems, REST APIs, protobuf, ZeroMQ, Kafka, gRPC
2w
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Software Engineer Senior (Networking)
King of Prussia or Littleton
OnsiteFull Time
5+ YOESenior software engineer with networking experience; Java/Python skills; strong problem-solving and collaboration.
Java, Python, REST APIs, Docker, Kubernetes, Elastic Stack, ActiveMQ, CI/CD, Web applications
5d
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Software Engineer, Senior
McLean or Chantilly or Beavercreek or Huntsville or Redstone Arsenal or Annapolis Junction or El Segundo or Rome or Aurora or Colorado Springs or Lexington
$87k-$198k/yr HybridFull Time
5+ YOE7+ years in software engineering; Rust, C, C++, or Python; full-stack app experience; Kubernetes; CI/CD; AI-assisted tools; secure-by-design; secret clearance; BS in CS/Engineering (5+ years) or 7+ years without degree.
Rust, C, C++, Python, Kubernetes, CI/CD, SonarQube, Clippy, cargo-deny, cargo-audit, PyO3
4w
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Senior Software Engineer, Network Tools with Python
Denver, Colorado, United States
$113k-$174k/yr OnsiteFull Time
7+ YOE7+ years in software development; strong Python, JavaScript, SQL, GraphQL; experience with databases; network protocols; automation tools; Linux; Docker; communication and collaboration skills.
Python, Javascript, SQL, GraphQL, Postgres, MySQL, MongoDB, Oracle, Docker, Ansible, Terraform, ServiceNow, Jira, Confluence, Google Suite
1mo
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Senior CNO Software Engineer
Aurora, Colorado, United States
OnsiteFull Time
14+ YOESenior CNO Software Engineer with 14+ years of technical experience (or 18+ with HS), strong Python/C/C++, CNO knowledge, and TS/SCI w/ Poly readiness.
Python, C, C++, Assembly, JIRA, Confluence, Crucible
2mo
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HPE Morpheus Software - Senior Software Engineer
Ft. Collins or Houston or Durham
$137k-$315k/yr HybridFull Time
8+ YOEBackend-focused software engineer with strong Java/Python/Linux experience; RESTful APIs, CI/CD, cloud knowledge; 8+ years, Bachelor’s in CS/Engineering.
Java, Python, Groovy, Ruby, Linux, RESTful APIs, SQL, NoSQL, Maven, Gradle, Git, CI/CD, AWS, Azure, Google Cloud
1mo
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Senior Software Engineer – SDA
Flagstaff or Broomfield or Remote
$140k-$180k/yr HybridFull Time
5+ YOE5+ years software engineering; defense/space industry experience; Agile; Linux, Python, SQL, Docker, AWS; U.S. security clearance eligible.
AWS, Lambda, ECS, PostgreSQL, SQL, Python, Docker, Linux, ETL, Machine Learning, SDA
2w
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Senior Software Engineer
Longmont, Colorado, United States
$115k-$145k/yr OnsiteFull Time
5+ YOE5+ years of professional software development; automation testing frameworks; Java, Python, JavaScript/TypeScript, or C#; backend services/APIs; CI/CD; AI-assisted tools.
Playwright, Cypress, Selenium, pytest, REST-assured, Criterion, Java, Python, JavaScript/TypeScript, C#, Copilot, Claude
1w
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Senior Network Software Engineer
Dallas - Fort Worth Metro Area or Denver Metro Area or San Francisco Bay Area
HybridFull Time
8+ YOE8+ years software engineering; proficient in Python/Django/Golang; relation databases; REST APIs; CI/CD.
Python, Django, Golang, PostgreSQL, MySQL, REST, CI/CD, Linux, Docker, Kubernetes, Ansible, Puppet, Chef, BGP, MPLS, Netflow, SNMP, TCP/IP, TLS, HTTP, UDP, DNS, Junos, IOS, EOS
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Senior Software Engineer
Aurora, Colorado, United States
$170k-$260k/yr OnsiteFull Time
14+ YOEActive TS/SCI with Polygraph; U.S. Citizenship; 14+ years software engineering experience and Bachelor's in Computer Science; strong independent and team work; excellent communication.
Python, AWS ML, Kubernetes, Docker, AI tools
3w
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Senior Software Developer
Louisville, Colorado, United States
$118k-$144k/yr OnsiteFull Time
5+ YOE5+ years in professional software development; strong Python; SQL; REST APIs; Git; CI/CD; excellent communication; Bachelor’s degree in CS/Software Engineering.
Python, SQL, Git, GitLab CI, pytest, REST APIs, JavaScript, TypeScript, Node.js
4d
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Software Engineer, Senior
McLean or Annapolis Junction or Aurora or Beavercreek or Chantilly or Colorado Springs or El Segundo or Huntsville or Lexington or Redstone Arsenal or Rome
$87k-$198k/yr HybridFull Time
7+ YOE7+ years of software engineering; Rust/C/C++/Python; full-stack; Kubernetes; CI/CD; security; TS/SCI or Secret clearance; BS in CS or Engineering or 5+ years exp.
Rust, C, C++, Python, Kubernetes, CI/CD, Code copilots, Static analysis tools
1w
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Senior Software Engineer (Full-Stack)
Denver, Colorado, United States
$160k-$210k/yr OnsiteFull Time
5+ YOE5+ years software engineering; strong React/TypeScript; Python/Django; GraphQL; PostgreSQL; AWS; monorepo; real-time UI; on-call.
React, TypeScript, WebRTC, Django, Python, GraphQL, PostgreSQL, AWS, Docker, WebSocket
3w
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Senior Software Developer
Louisville, Colorado, United States
$118k-$144k/yr OnsiteFull Time
5+ YOE5+ years of professional software development; strong SQL; Python; Git; REST APIs; pytest or similar testing; CI/CD experience; ability to own features end-to-end.
Python, SQL, Git, REST APIs, pytest, JavaScript, TypeScript, Node.js, CI/CD, GitLab CI
4d
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Senior, Software Engineer
Denver, Colorado, United States
$99k-$198k/yr OnsiteFull Time
7+ YOE7+ years software engineering; strong TypeScript/C#; Python or Go a plus; microservices; cloud (AWS/Azure); relational and NoSQL databases; Docker; strong problem solving.
TypeScript, C#, Python, Go, AWS, Azure, Docker, PostgreSQL, Cosmos DB, DynamoDB, ElastiCache, Microservices
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Senior Software Systems Engineer
Westminster, Colorado, United States
$134k-$161k/yr OnsiteFull Time
5+ YOEBachelor's in related field; 5-8 years in systems/software engineering; Python, C++, C, Java, Bash; experience decomposing system requirements; verification planning.
Python, C++, C, Java, Bash
2w
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Senior Software Engineer - ML Systems
Denver, Colorado, United States
$176k-$206k/yr RemoteFull Time
7+ YOE7+ years in software engineering with AI production systems (Python, PyTorch) and data services; experience with CI/CD and ML platforms; strong collaboration and regulatory awareness.
Python, PyTorch, SQL, Postgres, NoSQL, Redis, Airflow, MLflow, Kubernetes, Terraform, SageMaker, Databricks, Unity Catalog, Snowflake/Snowpark
3d
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Senior Software Engineer, Truework
San Francisco or Denver or San Francisco or Nashville or Santiago
$185k-$218k/yr HybridFull Time
5+ YOE5+ years software development; Python and JavaScript; RESTful APIs; Bachelor’s degree or equivalent; strong communication; ownership and collaboration; eager to learn.
Python, JavaScript, REST API
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Senior Engineer - Advanced Test Software
Aurora, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS in Engineering or related technical field; 4+ years experience; Python and Ruby; hardware interfacing; CI/CD; containerization; software lifecycle; security clearance not required to start but obtainable; strong communication.
Python, Ruby, Docker, Podman, CI/CD, Git, OpenC3 COSMOS, Linux, Windows, BASH, PowerShell, LabVIEW, Veristand, RF/Instrumentation
2w
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Sr Software Engineer
Lone Tree or Englewood
$143k-$197k/yr OnsiteFull Time
10+ YOESenior software engineer with 10+ years experience; BS in CS/Software Engineering; expert in C++, Java, Python; active Secret clearance.
C++, Java, Python, software development tools, requirements tracking, code reviews
2mo
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HPE Morpheus Software - Senior Software Engineer
Fort Collins or Houston or Durham
$144k-$273k/yr HybridFull Time
8+ YOE8+ years experience in backend software development with Java/Python/Groovy/Ruby, Linux, REST APIs, cloud, CI/CD, virtualization, ITSM; strong design, documentation, and collaboration skills.
Java, Groovy, Ruby, Python, Linux, REST, SQL, NoSQL, CI/CD, Maven, Gradle, Git, AWS, Azure, GCP, VMware
3w
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Senior Software Engineer - C++
Boulder, Colorado, United States
$130k-$170k/yr OnsiteFull Time
5+ YOE5+ years C++ experience; degree in engineering or CS; networking, video, Git/CMake; Windows/Linux/iOS; latency-critical software.
C++, Git, CMake, Make, Linux, Windows, Visual Studio, Python, CUDA, Vulkan, ARM Jetson, systemd, Ubuntu, Linux device drivers
5d
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Senior Software Engineer
Boulder, Colorado, United States
$145k-$175k/yr OnsiteFull Time
Foresight Diagnostics: Develops ultra-sensitive blood tests for cancer recurrence monitoring.
8+ YOE8+ years full-stack development; Python backend; React frontend; PostgreSQL; Docker/Kubernetes; AWS or GCP; strong problem-solving and communication.
Python, React, PostgreSQL, Docker, Kubernetes, AWS, GCP
2d
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Senior Software Engineer/Full Stack Developer
Denver or Naperville
HybridFull Time
7+ YOESenior software engineer with strong full-stack skills; experience with Java, Node.js, SQL, Python; design and develop web/cloud apps; 7+ years experience; hybrid in Naperville, IL or Denver, CO.
Java, Node.js, SQL, Python, APIs, Web Sockets, ClaudeCode, CoPilot, Unix, Shell scripting, MS SQL Server, PostgreSQL, Azure SQL, Oracle, JSON, HTTP
2w
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Senior Software Engineer
Warrenton or State College or Fort Eisenhower or Centennial
OnsiteFull Time
Strong Java and JavaScript/TypeScript skills; full-stack development; experience with Java, Python, JavaScript, Angular, React, ElasticSearch; BS in CS/CE/EE.
Java, Python, JavaScript, TypeScript, Angular, React, ElasticSearch, Docker, Kubernetes, Redis, REST, NoSQL, SQL, Xmidas
1mo
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Senior Software Engineer, Core Infrastructure
Irvine or Denver or Newport Beach or San Francisco
$100k-$210k/yr OnsiteFull Time
6+ YOE6+ years in software engineering; cloud infrastructure; DevOps/SRE; Python; Kubernetes; networking; security; startup experience.
Python, Kubernetes, Cloud, DevOps, CI/CD, Infrastructure as Code
1w
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Senior Software Engineer
San Francisco or Denver
$150k-$200k/yr HybridFull Time
5+ YOEBachelor’s in CS or related field; 5+ years software development; strong Python, Java, Spring Boot, Kafka; microservices; AI exposure; TDD; XP; PostgreSQL; Git; Jenkins.
Python, Java, Spring Boot, Kafka, PostgreSQL, Git, Jenkins, Docker, Kubernetes, Azure, AWS, Angular, JavaScript, CSS
3w
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Senior Software Engineer II
Denver or New York City or San Francisco
$174k-$210k/yr HybridFull Time
5+ YOE5–8 years software engineering; strong in TypeScript/Java/C#/Java, Python/JavaScript, SQL; CI/CD; cloud; real-time data; financial services experience preferred.
TypeScript, C#, Java, Python, JavaScript, Ruby, WebSockets, Kafka, PostgreSQL, MySQL, AWS, Azure, GCP, Git, GitHub, JIRA, CI/CD
2mo
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Senior Spacecraft Software Engineer
Boulder or Glasgow
$131k-$171k/yr HybridFull Time
Spire Global: Operates a satellite constellation providing data and global analytics.
Proficient in C++ or Python; FPGA development; DSP; GNSS signal processing; cloud-based systems; strong software engineering skills.
C++, Python, FPGA, VHDL, HLS, DSP, GNSS, AWS
1mo
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Senior Software Algorithm Engineer
Aurora or Philadelphia
$82k-$172k/yr OnsiteFull Time
5+ YOEBS in STEM fields; 5+ years software development; lead interdisciplinary team; TS/SCI clearance; Python/C/C++, Java, or Rust; domains SDA/SATCOM/SIGINT; willing to polygraph.
Python, C/C++, Java, Rust, Linux, AWS, CUDA, OpenCV, Git, Docker, Kubernetes, S3, EC2, Lambda
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Senior Ground Software Engineer I/II
Littleton, Colorado, United States
$120k-$170k/yr OnsiteFull Time
5+ YOEBachelor’s degree in engineering or technical field; 5+ years experience for Senior Ground Software Engineer I, 8+ years for II; U.S. citizenship required; proven web-based software architecture experience; strong systems thinking.
Python, Golang, Rust, TypeScript, Angular, PostgreSQL, InfluxDB, FastAPI, Git, CI/CD, Kubernetes
2mo
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Software Engineer, Senior
Aurora, Colorado, United States
$100-$120/hr OnsiteFull Time
20+ YOE20+ years of software engineering experience; experience in complex systems; TS/SCI clearance with polygraph; Bachelor's degree or HS Diploma with 24+ years of experience; strong communication and team collaboration.
Java, AWS, Docker, Kubernetes, JIRA, OCI containers, Python, Pydantic, ReactJS, SQL
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Software Engineer (Onsite)
Aurora, Colorado, United States
$108k-$205k/yr OnsiteFull Time
8+ YOESenior software engineer with 8+ years, strong Java/C++, Python, scripting, leadership experience, TS/SCI with poly, onsite in Aurora, CO.
Java, C++, Python, Perl, GIT, Java Script, TCL/TK, Bash
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Senior Engineer - Software Integration
Aurora, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS degree in Engineering with 4+ years, active TS/SCI clearance, experience in software test automation, embedded Linux, C/C++, Python, Ruby, Linux, CI/CD, and RTOS.
C/C++, Python, Ruby, Linux, Docker, CI/CD, GTest, RTOS, MATLAB
3mo
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Senior Program Analysis Software Engineer
San Francisco or New York City or Boston or Denver
$160k-$207k/yr HybridFull Time
Senior engineer for program analysis of code, with OCaml/Python experience; hybrid work in multiple US offices; familiarity with static analysis and performance optimization; strong collaboration with Security Research.
OCaml, Python, OpenTelemetry, Datadog
2mo
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HPE Morpheus Software - Senior Software Engineer
Fort Collins or Houston or Durham
$144k-$315k/yr HybridFull Time
8+ YOE8+ years backend development with Java/Groovy/Ruby/Python; Linux; REST APIs; SQL/NoSQL databases; virtualization; CI/CD; cloud (AWS/Azure/GCP); strong communication; system architecture.
Java, Groovy, Ruby, Python, Linux, REST, SQL, NoSQL, Maven, Gradle, Git, CI/CD, AWS, Azure, GCP, virtualization
1mo
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Senior I&T Software Engineer (Contract)
Arlington or Denver or Houston or Merritt Island
RemoteContract
9+ YOESenior software engineer with embedded/flight software, C/C++, and space hardware experience; 9+ years with Bachelor's or 7+ with Master’s; security clearance eligibility; US citizenship.
C, C++, Python, TCL, GNC, Embedded software, Hardware-in-the-loop, Test automation, RTOS
1mo
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Software Engineer
Chantilly or St. Louis or Gaithersburg or Denver
OnsiteFull Time
6+ YOESenior software engineer with 6+ years of experience; strong full-stack skills; cloud experience; DevSecOps focus; security clearance.
Python, Java, JavaScript, HTML, CSS, REST APIs, React, Angular, Vue.js, Node.js, Django, Flask, Docker, Kubernetes, AWS GovCloud, C2S, Azure, MySQL, PostgreSQL, SQL Server, Git, Jenkins, SonarQube, Nexus, Terraform, Keycloak, Vault, ArcGIS, OpenSearch, Elasticsearch
1mo
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Senior Software Engineer (Big Data)
Westminster, Colorado, United States
$89k-$165k/yr OnsiteFull Time
5+ YOE5+ years in distributed software development; Scala/Python/Java; Spark; AWS; Databricks; SQL; ETL/data pipelines; mentoring.
Python, Scala, Java, Apache Spark, Hadoop, Hive, AWS, Databricks, Kubernetes, Docker, Airflow, ELK, Git, SQL
1w
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Senior Engineer - Software Integration
Aurora, Colorado, United States
$97k-$165k/yr OnsiteFull Time
4+ YOEBS in Engineering with 4+ years related experience; active Secret clearance; experience in software test automation for C/C++, Python, Ruby; Linux; CI/CD; embedded and test software; on-site work.
C/C++, Python, Ruby, Rust, Linux, GTest, CI/CD, Docker, MATLAB
HiringCafe market data
Senior Python Software Engineer Jobs market signals in Frederick, CO, US
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
360+
Hiring companies
130+
Fresh sample
56% new in 30d
Salary visibility
83% show pay
Companies appearing in this market
BAE SystemsHewlett Packard EnterpriseBooz Allen HamiltonCableLabsAppleCACICesiumAstroForge Global
Work location mix in visible results
Onsite: 65Hybrid: 33Remote: 7