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Lead Python Developer Jobs in Millbrae, CA, US

470+ lead python developer jobs from 230+ companies hiring in Millbrae, CA, US.

479 jobs- Millbrae • 50 miles
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Hardware Systems Engineer
San Bruno, California, United States
$195k-$255k/yr OnsiteFull Time
Mill
Mill: Provides smart kitchen bins that recycle food waste.
5+ YOE5+ years hands-on systems/lead roles with thermal/fluid handling; cross-functional collaboration; Python for time-series analysis; experience with electromechanical integration; startup experience preferred.
Python
2mo
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Founding Robotic Engineer - FTE
San Francisco, California, United States
$150k-$250k/yr HybridFull Time
Maven Robotics
Maven Robotics: Building general-purpose AI robots for industrial manufacturing environments.
Lead founding robotics engineer role building real-robot systems, including teleoperation, data pipelines, and ML infrastructure; requires hands-on robotics, ROS/ROS2, Python/C++, and hardware experience.
ROS/ROS2, Python, C++, Real-time systems, Networking
2mo
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Senior Staff Engineer, Physical Implementation CAD Lead
Austin or San Jose
$180k-$297k/yr OnsiteFull Time
Samsung Electronics
Samsung ElectronicsKorea Exchange: 005930: Manufacturer of consumer electronics, semiconductors, and home appliances.
11+ YOEExtensive experience in physical design CAD, P&R flows, scripting, and leadership in GPU/SoC design.
Cadence, Synopsys, P&R, Static Timing Analysis, Calibre, ICV, Python, Tcl, Shell
2w
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Senior Controls Engineer
Livermore, California, United States
$200k-$260k/yr OnsiteFull Time
Inertia
Inertia: Building laser systems and fuel targets for commercial fusion power.
10+ YOELead design and implementation of control systems for high-energy laser platforms; 10+ years in controls; PLC, embedded and real-time software; C/C++, Python; motion control; system integration.
PLC programming, Embedded systems, Real-time software, C/C++, Python, MATLAB/Simulink
1w
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Workplace Research Lead
Chicago or Los Angeles or Arlington or San Francisco or Seattle or Boston or San Jose
OnsiteFull Time
Avanade
Avanade: Provides Microsoft-focused IT consulting and digital transformation services.
3+ YOEPhD preferred or Master’s in I/O psychology/related field; 3+ years applied research in industry; experience with mixed methods, client-facing work, and AI tools.
Power BI, Python, R
2w
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Senior Firmware Engineer-IoT
Brisbane, California, United States
$150k-$180k/yr HybridFull Time
Avive
Avive: Sells connected automated external defibrillators and emergency medical software.
4+ YOELead embedded firmware development for medical devices; 4+ years in firmware; bachelor in EE/CE; strong C/C++; experience with FDA IEC 62304; collaborative, problem-solving.
C, C++, RTOS, Bare Metal, Linux, Python, Git, Jira, SPI, I2C, UART, I2S, USB, BLE, Wi-Fi, GNSS, Cellular, Oscilloscope, Logic Analyzer, Multimeter, Power Supply
2mo
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Senior Embedded Software Engineer (Firmware / Embedded Linux)
San Bruno, California, United States
HybridFull Time
Empo Health
Empo Health: Develops in-home scales for diabetic foot ulcer detection.
10+ YOE10+ years of direct firmware experience; strong C/C++ on Linux; Yocto/OpenEmbedded; BS/MS in Electrical/Computer Engineering or Computer Science; lead firmware projects; onsite in San Bruno 3 days/week.
Yocto, OpenEmbedded, C/C++, Python, Bash, Linux
2w
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Staff Electrical Engineer
San Francisco, California, United States
$154k-$230k/yr OnsiteFull Time
Ouster
OusterNASDAQ: OUST: Designs and manufactures high-resolution digital lidar sensors.
12+ YOELead hardware development for LIDAR, drive electrical system architecture, and execute from concept to production; 12+ years analog/digital design; embedded SoC; PCB/HDI expertise.
Altium, HDI PCB, Schematic capture, Ethernet, CAN, I2C, SPI, USB, Python, FPGA, ARM, DSP, HDI multi-layer PCB
3w
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Senior Systems Engineer
San Jose, California, United States
$160k-$180k/yr OnsiteFull Time
PROCEPT BioRobotics
PROCEPT BioRoboticsNASDAQ: PRCT: Develops robotic systems for minimally invasive prostate surgery.
5+ YOELead system-level verification and validation (V&V) for a regulated medical device; develop and refine system requirements; design and automate tests; ensure traceability and cross-functional collaboration.
Python, MATLAB, C++, LabVIEW
2mo
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Principal Engineer, AI System Architect (Hardware)
San Jose, California, United States
$219k-$351k/yr OnsiteFull Time
Samsung Semiconductor
Samsung SemiconductorKRX: 005930: Designs and manufactures memory chips and semiconductor solutions.
15+ YOEPhD in CS/EE with 15+ years in large-scale AI system architecture; strong modeling/simulation; Python, C++, PyTorch; lead architecture decisions and cross-team collaboration.
Python, C++, PyTorch
1mo
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Guidance, Navigation & Control Engineer IV (Staff)
Sunnyvale, California, United States
OnsiteFull Time
Lockheed Martin
Lockheed MartinNYSE: LMT: Designs and manufactures global security and aerospace systems.
5+ YOELead GN&C team; strong MATLAB/Simulink, Python/C/C++, control theory, and leadership experience.
MATLAB, Simulink, Python, C, C++, Fortran, MBSE (Cameo), IBM DOORS
3w
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Test Engineer Manager
Fremont, California, United States
$120k-$140k/yr OnsiteFull Time
Quanta Manufacturing
Quanta ManufacturingTWSE: 2382: Electronics design and manufacturing services for global technology brands.
4+ YOE2+ MgmtLead Test Development Engineering team; implement automated test strategies; 4+ years hardware test/validation with 2+ years in leadership;Bachelor’s in EE/CE/CS; server/system manufacturing experience preferred.
Python, Linux, Git, test_infrastructure_technologies
2mo
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ASIC Design Verification Engineer
San Jose, California, United States
$165k-$241k/yr OnsiteFull Time
Cisco
CiscoNASDAQ: CSCO: Provides networking, security, and collaboration technology solutions globally.
7+ YOEBachelor's +7 yrs or Master's +4 yrs or PhD +1 yr; SystemVerilog, UVM; verification strategies for ASIC; lead verification teams; scripting (Python, Perl) and C/C++.
SystemVerilog, UVM, emulation, Python, Perl, C/C++
2mo
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Staff Aerodynamics Engineer, Flight Test & Certification
San Jose, California, United States
$152k-$209k/yr OnsiteFull Time
Archer Aviation
Archer AviationNYSE: ACHR: Designs and builds all-electric vertical takeoff and landing aircraft.
4+ YOELead aerodynamic testing and certification; 10+ yrs flight test in fixed-wing/rotorcraft; FAA cert experience; Python or MATLAB; fast-paced design environment.
Python, MATLAB/Simulink, Git, CI/CD, Conda
1mo
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Staff - Senior Staff Product Application Engineer
San Jose, California, United States
$110k-$175k/yr OnsiteFull Time
SK hynix Memory Solutions America
SK hynix Memory Solutions AmericaKorea Exchange: 000660: Develops semiconductor controllers and firmware for enterprise data storage.
5+ YOELead a team to design and execute test plans for PCIe and NVMe eSSDs; manage testing, triage failures, and coordinate with SOC/FW/HW; 5+ years in storage; strong Python/C/C++ skills.
NVMe, PCIe, NVMe-MI, SMBus, Python, C, C++, Linux kernel
2mo
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Principal Site Reliability Engineer (SRE)
Dallas or San Francisco or Austin
$180k-$210k/yr RemoteFull Time
InfiniteChoice
InfiniteChoice: Builds and scales consumer brands using an automation-first platform.
12+ YOE5+ Mgmt12+ years SRE/Infrastructure, 5+ years leading SRE teams, strong Python/Go/Java, GCP expertise, Docker/Kubernetes, monitoring, AI/ML for SRE, incident management, budgeting and capacity planning, distributed systems knowledge
Python, Go, Java, Prometheus, Grafana, Datadog, New Relic, Docker, Kubernetes, Cloud Monitoring, Cloud Logging, Cloud Trace, GKE, Compute Engine, Cloud Functions
2mo
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R&D Test Engineer
Alameda, California, United States
$128k-$162k/yr OnsiteFull Time
Sila Nanotechnologies
Sila Nanotechnologies: Produces silicon-based materials to improve battery energy density.
4+ YOEExperience leading experimental R&D projects; strong lab testing, data analysis in Python; knowledge of mechanical, thermal systems; BS in engineering or physical sciences; 4+ years experience; ability to operate lab instruments and electronics.
Python, Laboratory instrumentation, Electronics, Data analysis software
3w
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Staff Systems Engineer
Milpitas, California, United States
OnsiteFull Time
Graphcore
Graphcore: Produces specialized processors for artificial intelligence workloads.
Lead hardware engineering with server hardware, diagnostics, and bring-up support.
Python, Bash, Linux, Firmware, Diagnostics tools
21h
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Senior Staff ML Engineer
Palo Alto, California, United States
$220k-$247k/yr HybridFull Time
Typeface
Typeface: Generative AI platform for personalized enterprise marketing content.
12+ YOE12+ years building and scaling ML systems; Staff+ level impact; Master’s or PhD in CS or related field; experience leading multi-team or company-wide technical strategy; deep ML infrastructure expertise; Python plus systems programming.
Python, C/C++
4d
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Chief GenAI Engineer
Sacramento or Oakland
HybridFull Time
California Office of Data and Innovation
California Office of Data and Innovation: Modernizing California government services through design, data, and technology.
Lead design and delivery of AI solutions; hands-on engineering with cloud platforms; mentor and ensure responsible AI.
Python, Cloud platforms, MLOps, RAG, Snowflake
1mo
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Senior Field Engineer
Berkeley, California, United States
$120k-$140k/yr OnsiteFull Time
Ambi Robotics
Ambi Robotics: AI-powered robotic systems for e-commerce warehouse automation.
3+ YOE3+ Mgmt3+ years in field engineering or technical operations; experience leading distributed teams; travel up to 50%; hardware and software product support.
Jira Service Management, Grafana, Python, Linux, Command Line Interface
1mo
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Staff Application Engineer
San Jose, California, United States
$145k-$185k/yr HybridFull Time
Renesas Electronics
Renesas ElectronicsTokyo Stock Exchange: 6723: Designs and manufactures semiconductors for automotive and industrial systems.
7+ YOELead memory system validation and USB protocol engineering; 7+ years in power management and memory system design; Bachelor's or Master's in Electrical Engineering.
LabVIEW, Python, USB protocol testing, Power management testing
2d
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Principal Data Engineer
San Francisco, California, United States
$207k-$276k/yr HybridFull Time
Early Warning Services
Early Warning Services: Operates payment and risk solutions for the financial industry.
15+ YOE15+ years in software, FinTech, leading cross-functional teams; expert in data engineering, SDLC, cloud, and architectures; hands-on with Java, microservices, big data, and CI/CD.
Java, Spring, Microservices, Kafka, Oracle, SQL, JavaScript, Python, Hadoop/S3, Spark, TensorFlow, PyTorch, CI/CD, Git, Jenkins, Terraform, AWS, GCP, Azure, Jira, Confluence
2mo
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Compliance Technology Oversight Lead
Oakland, California, United States
$218k-$327k/yr RemoteFull Time
Block
BlockNYSE: XYZ: Creates financial tools for businesses and individuals.
10+ YOE10+ years in compliance technology for regulated financial institutions or FI consulting; ML and heuristic model experience; data monitoring and model performance oversight; regulatory exam responses; agile development.
Machine Learning, Data Visualization, Agile, Python, Model Monitoring
1mo
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Forward Deployed Engineer
San Francisco or New York City
HybridFull Time
Cursor
Cursor: AI-powered code editor for professional software developers.
Lead discovery with customer engineers; design and build Cursor-powered workflows; ship production-ready systems; own production quality and communicate tradeoffs; collaborate with leadership; turn builds into reusable Cursor patterns.
Python, TypeScript, JavaScript
1d
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Sr Cell Design Engineer
San Jose, California, United States
$128k-$192k/yr OnsiteFull Time
Lyten
Lyten: Manufactures graphene-enhanced batteries, materials, and industrial sensors.
3+ YOELead pouch cell design and manufacturing scale-up; strong CAD/PLM skills; battery design expertise; cross-functional collaboration.
SolidWorks, PLM, Python, R, MATLAB, Excel
2mo
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Sr Staff /Staff DFT Engineer
Bangalore or Palo Alto or Austin
OnsiteFull Time
Mythic
Mythic: Designing analog-based AI processors for edge and cloud computing.
8+ YOELead end-to-end DFT implementation and verification for complex SoC; MBIST, IJTAG, Scan, ATPG; pre-silicon test planning; collaborate with RTL, physical, STA, and analog design teams.
TetraMAX, DFT Compiler, Tessent, Verilog, SystemVerilog, Python, Perl, Tcl
1mo
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Staff Engineer - Cloud Test
Santa Clara, California, United States
$174k-$204k/yr RemoteFull Time
Aviatrix
Aviatrix: Provides secure multi-cloud networking and cloud-native network security.
6+ YOELead test strategy, design plans, drive automation for cloud networking and security features; mentor engineers.
Python, Shell, Golang, Kubernetes, AWS, Azure, GCP, OCI
2mo
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Client Engineer III (MedInsight)
Seattle or Appleton or Atlanta or Boise or Wakefield or Chicago or Dallas or Hartford or Omaha or San Francisco or Portland or Portland
$85k-$162k/yr RemoteFull Time
Milliman
Milliman: Provides actuarial consulting and risk management solutions globally.
5+ YOE5+ years in analytics/data engineering with client-facing delivery; expert SQL; dimensional modeling; strong software engineering practices; able to lead data-driven implementations.
SQL, Git, CI/CD, ETL, Data Modeling, Python, Cloud
6d
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Knowledge Engineer / Semantic Expert for AI
Mountain View or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego
HybridFull Time
Accenture
AccentureNYSE: ACN: Global provider of management consulting and technology services.
12+ YOELead Knowledge Graph and AI solutions; design ontologies; build end-to-end data pipelines; team leadership; strong RDF/graph DB expertise.
RDF, SPARQL, LPG, SHACL, Neo4J, Stardog, Amazon Neptune, Python, TensorFlow, PyTorch, Airflow, NiFi, LLMs
2mo
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Principal Electrical Design Engineer
Palo Alto, California, United States
$220k-$270k/yr OnsiteFull Time
Array Labs
Array Labs: Building radar satellite clusters for high-resolution 3D Earth mapping.
15+ YOELead design and validation of digital and mixed-signal electronics for radar payloads and satellite platforms; 15+ years of electronics design experience.
Altium Designer, OrCAD, Allegro, LTspice, ADS, Microwave Office, MATLAB, Python, Oscilloscopes, Network Analyzers
2w
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Principal Design Verification Engineer
Sunnyvale, California, United States
$250k-$280k/yr OnsiteFull Time
Bolt Graphics
Bolt Graphics: Designing high-efficiency graphics processors for professional rendering and simulation.
12+ YOELead verification strategy for ASIC/SoC with 12–15 years exp; strong leadership; expert in SystemVerilog/UVM; hands-on with DV environments.
SystemVerilog, UVM, SVA, Constrained-Random Verification, Synopsys VCS, Cadence Xcelium, Verdi, SDF, UPF/CPF, CDC/RDC, Emulation platforms (ZeBu), Python, TCL
1mo
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Principal Software Engineer, B2B Engineering
San Francisco, California, United States
$385k-$490k/yr OnsiteFull Time
OpenAI
OpenAI: Develops artificial intelligence models and generative AI software services.
Design and scale backend services; lead architecture of distributed systems, databases, data pipelines; ensure security, reliability, and API quality; strong collaboration across teams.
Python, Go, Rust, TypeScript
4w
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Design Engineer 2 - San Jose, CA
San Jose, California, United States
$100k-$150k/yr OnsiteFull Time
M.C. Dean
M.C. Dean: Designs and builds cyber-physical systems for mission-critical facilities.
2+ YOEDesign engineer with engineering degree and 2+ years, knowledge of electronic security systems, and ability to lead design and coordination efforts.
AutoCAD, Revit, Microsoft Windows Server, PowerShell, Python, SQL, VMware
2mo
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Senior Principal Laser Quality Engineer
Milpitas, California, United States
$175k-$220k/yr OnsiteFull Time
MKS Instruments
MKS InstrumentsNASDAQ: MKSI: Provides instruments and process control solutions for advanced manufacturing.
10+ YOELead quality engineering for laser products; NPI, PFMEA, DoE, CAPA; ISO 9001; 10+ years in quality engineering; 7+ years in laser/photonics; strong analytical skills.
Minitab, MATLAB, Python, C++, Six Sigma, DOE, Gage R&R
1w
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Principal Thin Film Process Engineer
San Jose, California, United States
$131k-$187k/yr OnsiteFull Time
Lumentum
LumentumNASDAQ: LITE: Manufacturer of optical and photonic components for global networks.
10+ YOELead SME for PVD and EB evaporation; 10+ years in semiconductor processing; HVM focus; strong analytical and leadership skills.
Python, MATLAB, JMP, Minitab, Ellipsometry, SEM-EDX, TEM, AFM, XPS, FIB, XRR, SAXS, FTIR, Defect Metrology, DOE, SPC, PVD, EB Evaporation, Sputter Coating
3w
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Staff Reinforcement Learning Engineer – Whole Body Control
San Jose, California, United States
$150k-$250k/yr OnsiteFull Time
Figure
Figure: Develops autonomous humanoid robots for commercial and residential tasks.
Strong dynamics/control background for legged robots; RL for robotics (PPO, SAC); tune hyperparameters; apply domain randomization and curriculum learning; lead projects and mentor.
Python, PyTorch, ROS
2w
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Sr Staff Engineer, Equipment Controls
Fremont, California, United States
$152k-$218k/yr OnsiteFull Time
Bloom Energy
Bloom EnergyNYSE: BE: Manufactures solid oxide fuel cell systems for onsite power.
8+ YOELead architecture of integrated control systems; MES/SCADA; PLCs; cross-functional collaboration; on-site, full-time role in Fremont.
Allen Bradley PLC, SCADA, MES, HMI, motion controls, robotics, Python, C, C++, Keyence LJ-V, XG-XG-X, P&ID, ETC
1mo
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Staff Research Scientist, Technical Lead (AdTech/Recommender Systems)
San Mateo, California, United States
$220k-$280k/yr HybridFull Time
Cognitiv
Cognitiv: Deep learning platform for predictive advertising and media buying.
5+ YOE2+ MgmtSenior ML leader with 5-7+ years in ML R&D; hands-on coding and production deployment; strong PyTorch/LLM experience.
Python, PyTorch, XGBoost, PCA, Spark, Hadoop, AWS, GCP, Azure, C++
6d
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Engineering Manager, Internal Platform
San Francisco or New York
$240k-$260k/yr HybridFull Time
Baseten
Baseten: Scalable infrastructure platform for deploying and serving AI models.
Leading and growing a platform engineering team; strong Go/Python, Kubernetes, CI/CD; monorepos; developer tooling; cross-functional leadership.
Go, Python, Kubernetes, Docker, Helm, Monorepo tooling, CI/CD

HiringCafe market data

Lead Python Developer Jobs market signals in Millbrae, CA, US

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
470+
Hiring companies
230+
Fresh sample
41% new in 30d
Salary visibility
78% show pay

Companies appearing in this market

CiscoBloom EnergyEarly Warning ServicesOpenAIAccentureAmbi RoboticsArcherArcher Aviation

Work location mix in visible results

Onsite: 27Hybrid: 15Remote: 4