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Lead Python Developer Jobs in Minnesota, United States

340+ lead python developer jobs from 220+ companies hiring in Minnesota, United States.

347 jobs- Minnesota
1w
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Lead Value Engineer
United States
RemoteFull Time
SingleStore
SingleStore: Real-time distributed SQL database for transactions and analytics.
7+ YOE7+ years technical pre-sales/value engineering; Masters or MBA with relevant experience; strong comms for C-Suite; SQL, analytics tools; cloud platforms; large-scale DBs.
ANSI SQL, Excel, Python, AWS, Azure, GCP, VMware
2mo
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Lead Network Engineer
United States
$112k-$156k/yr RemoteFull Time
HealthEdge
HealthEdge: Cloud-based administrative software for healthcare insurance providers.
7+ YOE1+ Mgmt7+ years of hands-on network engineering in enterprise environments; 1-2 years of people leadership; strong enterprise networking, security, and vendor management.
Cisco, Aruba, Palo Alto, Meraki, SD-WAN, VPN, VLAN, AWS, Azure, Python, Ansible
1d
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Lead DevOps Engineer
United States
$90k-$145k/yr RemoteFull Time
Hilton
HiltonNYSE: HLT: Operates and franchises a global portfolio of hotels and resorts.
5+ YOEFive years in technology; four years with CI tools; three years Kubernetes; three years on AWS; scripting in Bash; on-call reliability experience; travel up to 10%.
GitLab, Bamboo, CI/CD tooling, Kubernetes, Docker, Terraform, Python, Shell, JavaScript/Java
2mo
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Lead Engineer - Advanced Data Science for Aerospace Systems
Newport News or Arlington or St Paul or Ronkonkoma
$100k-$155k/yr HybridFull Time
North Wind
North Wind: Provides research, development, and testing for hypersonic aerospace systems.
7+ YOELead engineer with 7–10 years in aerospace engineering, AI/ML, CFD/FEA, and team leadership.
CFD, FEA, Machine Learning, AI, Python, MATLAB
1mo
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Fullstack Engineer
United States
$150k-$225k/yr RemoteFull Time
OLarry
OLarry: AI-powered tax advisory platform for high-net-worth individuals and businesses.
Lead fullstack development with React/Next.js; backend Node.js/Python; REST APIs; SQL/NoSQL; cloud (AWS/GCP); fintech familiarity; agile Design Sprint.
React, Next.js, Node.js, Python, REST APIs, SQL, NoSQL, AWS, Google Cloud, Figma
4w
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Lead Engineer- Advanced Computational Methods for Power Systems (62577)
United States
$105k-$154k/yr RemoteFull Time
Eaton
EatonNYSE: ETN: Manages electrical, hydraulic, and mechanical power systems globally.
PhD or PhD candidate within 6 months; or Master's with 3 years experience; or Bachelor's with 5 years; strong Python/MATLAB and ML experience; no immigration sponsorship accepted.
Python, MATLAB, PyTorch, TensorFlow, Google Cloud, Docker, Kubernetes
1mo
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Sr. Lead Software Engineer - 11282
United States
$149k-$194k/yr RemoteFull Time
Coupa
Coupa: Cloud-based platform for managing and optimizing business expenditures.
10+ YOE8-10+ years in software/platform engineering; strong Python/SQL; data ingestion and pipelines; cloud (AWS/GCP/Azure); Databricks/BigQuery/Snowflake; Lakehouse; experience with Presto/Trino; Iceberg/Delta Lake.
Python, SQL, Databricks, BigQuery, Snowflake, Presto, Trino, Iceberg, Delta Lake, AWS, GCP, Azure
1mo
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Lead AI Cloud Platform Engineer
United States
$110k-$181k/yr RemoteFull Time
Allstate
AllstateNYSE: ALL: Provides insurance products for vehicles, homes, and businesses.
7+ YOE7+ years of experience; GenAI on cloud platforms; Azure/AWS; Terraform; Python; Cloud IaC; AI services.
Azure, AWS, Google Cloud, Terraform, Python, Vertex AI, Bedrock, OpenAI
5d
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AI Red Team Lead Engineer
Minneapolis or Atlanta or Cincinnati or New York or Chicago or Gresham or Charlotte or Irving or Earth City
$133k-$157k/yr HybridFull Time
U.S. Bank
U.S. BankNYSE: USB: Provider of personal, business, and institutional financial services.
8+ YOELead AI red team operations; design, execute, and report on AI/ML security testing; mentor engineers; strong cybersecurity and AI knowledge.
Python, PowerShell, Go, C++, Shell
3mo
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Tech Lead/Data Engineer III
Minnetonka or Madison
$100k-$172k/yr HybridFull Time
Medica
Medica: Provides health insurance coverage and health plan administration services.
5+ YOEExperience in enterprise data, cloud data engineering, SQL proficiency, and healthcare data environment; lead data initiatives and design scalable ETL pipelines.
Snowflake, Azure, AWS, Apache Airflow, dbt, Informatica IDMC, Apache Spark, Power BI, Tableau, Python, R, TensorFlow, Azure Machine Learning, scikit-learn, PyTorch
9h
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Lead Infrastructure Engineer III
Boise or United States
$130k-$140k/yr RemoteFull Time
Truckstop
Truckstop: Provides a digital marketplace for freight matching and logistics.
8+ YOEExtensive cloud infrastructure experience with Kubernetes, Terraform, IaC, automation, monitoring, security, and leadership.
Kubernetes, AKS, EKS, Terraform, Chef, Packer, Puppet, New Relic, Azure, AWS, GitLab, GitHub Actions, PowerShell, Python, YAML, Kafka, .NET, Node.js, Linux, IAM, REST, GraphQL
1w
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Staff Software Engineer - Back End (Remote)
United States
$125k-$145k/yr RemoteFull Time
Ad Hoc
Ad Hoc: Providing user-centered digital services to federal government agencies.
9+ YOE9+ years of engineering; Python, Django; API integration; backend development; independently lead delivery.
Python, Django, APIs
1mo
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Sr. Software Engineer
United States
$100k-$160k/yr RemoteFull Time
Learning.com
Learning.com: Provides K-12 digital literacy and computer science curriculum.
5+ YOE5+ years of software development; senior/lead experience; strong full-stack skills; React/Angular; C#, Python, JavaScript; SQL and microservices; remote-ready; excellent communication.
C#, Python, JavaScript, React, Angular, SQL, REST APIs, Microservices
1mo
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Tech Lead - Senior Software Engineer
New York or United States
$200k-$230k/yr RemoteFull Time
YipitData
YipitData: Providing alternative data and research for institutional investors.
6+ YOE2+ Mgmt6+ years software development; 2+ years in technical leadership; shipped SaaS; strong system design; stack: Python, TypeScript/React, AWS; AI-native workflows; Bachelor's or Master's in CS or STEM.
Python, TypeScript, React, AWS, Databricks, Claude Code, Cursor, Codex
2mo
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Senior Software Engineer
United States
$94k-$179k/yr RemoteFull Time
Mercury Insurance
Mercury InsuranceNYSE: MCY: Provides personal and commercial property and casualty insurance products.
5+ YOEBachelor’s degree in CS/IS or related field; 5+ years software development; 2+ years leading/mentoring teams; strong Java/Python/Go/JavaScript; AWS, Kafka are a plus; CI/CD experience; cloud familiarity.
Java, Python, Go, C++, JavaScript, Apache Kafka, AWS, S3, Docker, Kubernetes, NI Fi, SQS, REST, gRPC, CI/CD
1mo
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Lead AI & Data Infrastructure Engineer
United States
$140k-$175k/yr RemoteFull Time
Matium
Matium: Digital marketplace for industrial raw material trading.
6+ YOE6+ years in data engineering, ML or applied AI; proficient in Python, SQL, data stack; experience deploying ML models; familiarity with recommender systems/marketplace algorithms; distributed data systems; scalable data pipelines; startup environment.
Python, SQL, Cloud platforms, Data pipelines, Machine learning, Big data technologies
4w
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Software Engineer, Growth
North America
$90k-$230k/yr RemoteFull Time
Monarch Money
Monarch Money: A subscription-based platform for personal budgeting and wealth management.
5+ YOE5+ years software engineering; Python, TypeScript, React; lead complex projects; remote collaboration.
Python, TypeScript, React, A/B testing, Analytics
3w
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Senior Migration Lead - Application
United States
RemoteFull Time
Quantiphi
Quantiphi: Provides applied AI research and data engineering services.
8+ YOEExperience leading application migration and modernization to AWS; strong full-stack development; CI/CD; AWS knowledge; 8+ years.
AWS, Java, C#, Node.js, Python, TypeScript, React, Angular, REST, Git, CI/CD
2w
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Lead Systems HPC Engineer
United States
$170k-$300k/yr RemoteFull Time
Nebius
NebiusNasdaq: NBIS: Builds cloud infrastructure and software for artificial intelligence development.
5+ YOE5+ years system-level software, 3+ years Linux, HPC, perf optimization, low-level programming.
Linux, KVM, QEMU, MPI, NCCL, InfiniBand, RoCE, PCIe, C/C++, Go, Python
2mo
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Technical Lead - Product Engineering
United States
RemoteFull Time
OpenLoop
OpenLoop: Provides white-label infrastructure and clinical support for virtual care.
8+ YOE8+ years software engineering; 2+ years leading projects; experience building operational products; AI systems in production; Proficient in Go, Python, or TypeScript; distributed systems; containerized deployments.
Go, Python, TypeScript, Docker, Kubernetes, Cloud Run, Pub/Sub, BigQuery, LangFuse, FHIR, HL7
2mo
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Principal Software Engineer, ChemDraw (C++, Web Development, TypeScript) - Remote US
United States
$142k-$180k/yr RemoteFull Time
Revvity
RevvityNYSE: RVTY: Sells diagnostic instruments and reagents for health research.
5+ YOE5+ years software development experience; strong C/C++, C#, Python desktop and 4+ years web development; prior technical lead/mentoring experience; knowledge of Windows/Mac/Linux development; UI/UX and Cheminformatics/Bioinformatics familiarity.
TypeScript, C++, C, Python, JavaScript, HTML, CSS, VS Code
3w
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Principal Software Engineer - Integration
United States
$190k-$260k/yr RemoteFull Time
Stellar Cyber
Stellar Cyber: Unified platform for automated cyber threat detection and response.
8+ YOEBachelor’s or Master’s in CS/Engineering; 8+ years backend software development; 3+ years in staff-level/tech lead; proficient in Python, Go, or Java; strong API, microservices, distributed systems; mentoring and strong communication.
Python, Go, Java, Kafka, RabbitMQ, Celery, Airflow, REST, GraphQL, OAuth, API Keys, Rate Limiting, Kubernetes, Helm, AWS, Azure, GCP, LLM APIs, MCP
2mo
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Staff Engineer - Technical Lead
San Francisco or United States
$120k-$150k/yr RemoteFull Time
Arine
Arine: Platform for optimizing medication therapy and improving healthcare outcomes.
10+ YOE10+ years in backend software and systems; strong Python and infrastructure expertise; leadership in technical delivery; healthcare data security and privacy awareness.
Python, AWS, Serverless, CloudFormation, CI/CD, Security best practices
2mo
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Lead Machine Learning Operations Engineer - Ad Tech
Richfield, Minnesota, United States
$121k-$217k/yr HybridFull Time
Best Buy
Best BuyNew York Stock Exchange: BBY: Retailer of consumer electronics, home appliances, and technology services.
5+ YOEBachelor's in related field; 5 years MLOps; 5 years Python; 5 years production data/model-serving; SQL; ad tech experience.
Python, SQL, Airflow, Flyte, Cloud Composer, Step Functions, ML platforms, ML pipelines
1mo
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Staff Software Engineer - Tech Lead
United States or Canada
RemoteFull Time
Cerby
Cerby: Secures nonstandard applications that lack modern identity standards.
6+ YOE6+ years software engineering; strong system design; leadership experience; product-led mindset; able to balance short-term delivery with long-term scalability.
Python, Go, AWS, OIDC, SAML, SCIM, JWT, OpenTelemetry, Datadog
2mo
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Lead Identity Engineer (Entra ID & Okta)
United States
RemoteFull Time
By Light
By Light: IT and cybersecurity services for federal and defense agencies.
5+ YOESenior-level expertise in Microsoft Entra ID and Okta; strong SSO, MFA, lifecycle, federation experience; proven project leadership and cross-functional coordination; strong communication.
Microsoft Entra ID, Okta, SAML, OIDC, OAuth2, SCIM, Graph API, PowerShell, Python
1mo
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QA Engineer Lead (fixed-term contract)
United States
RemoteContract
Sertis
Sertis: Provides bespoke AI and data solutions for enterprise transformation.
4+ YOE4+ years in QA, test automation, or backend testing with Java; design and scale automation; API testing; CI/CD integration; microservices; production-ready testing.
Selenium, Playwright, Cypress, Postman, RestAssured, Java, JavaScript, Python, CI/CD, JMeter, Docker, Kubernetes, Observability tools
5d
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Software Engineer
Boston or United States
$108k-$192k/yr RemoteFull Time
AcuityMD
AcuityMD: Commercial intelligence platform for the medical technology industry.
1+ YOEBachelor's degree in CS/Software Eng or related field plus 1 year of experience; skills include JavaScript, TypeScript, React, Node.js, Python, Mongo, data analytics, UX analytics, and leading projects.
JavaScript, TypeScript, React, Node.js, Python, MongoDB, Data Analytics Tools, UX Analytics
2mo
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Tech Lead, Data Engineering
United States
$165k-$175k/yr RemoteFull Time
Vida Health
Vida Health: Virtual care platform treating physical and mental health conditions.
6+ YOE2+ MgmtLead backend engineering; 6+ years; Python (FastAPI); PostgreSQL; API design; architecture; 2+ years leadership; remote work eligible.
Python, FastAPI, PostgreSQL
2w
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Lead Performance Test Engineer IV
Edina, Minnesota, United States
$130k-$155k/yr HybridFull Time
Western National Insurance Group
Western National Insurance Group: Provides property and casualty insurance to individuals and businesses.
10+ YOETen+ years in performance testing; expert in workload modeling, test automation, and CI/CD integration; strong leadership; bachelor’s degree; relevant certifications considered.
JMeter, Gatling, BlazeMeter, K6, Locust, LoadRunner, Java, Python, Groovy, Scala, Jenkins, GitLab, Docker, Kubernetes, Prometheus, Grafana, Datadog, Dynatrace, New Relic
2w
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Lead Performance Test Engineer IV
Edina, Minnesota, United States
$130k-$155k/yr HybridFull Time
Western National Insurance Group
Western National Insurance Group: Provides property and casualty insurance for individuals and businesses.
10+ YOE10+ years enterprise performance testing; expert in workload modeling, CI/CD integration, test automation, and cross-team leadership.
JMeter, Gatling, BlazeMeter, K6, Locust, LoadRunner, Java, Python, Groovy, Scala, Jenkins, GitLab, Docker, Kubernetes, Prometheus, Grafana, Datadog, Dynatrace, New Relic
2mo
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Lead Site Reliability Engineer (51136)
United States
$125k-$206k/yr RemoteFull Time
OpenText
OpenTextNASDAQ: OTEX: Develops enterprise software for information management and digital transformation.
SRE with Kubernetes, AWS, Terraform, Helm; CI/CD; Linux/Windows; monitoring; scripting; cloud security; on-call experience.
Kubernetes, AWS, Helm, Terraform, Prometheus, Grafana, ELK, Python, Bash, Linux, Windows
2w
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Lead ML/AI Engineer (US)
United States
$175k-$215k/yr RemoteFull Time
Penguin Solutions
Penguin SolutionsNASDAQ: PENG: Provides high-performance AI and edge computing infrastructure solutions.
7+ YOE2+ Mgmt7+ years in software/DevOps/ML; 2+ years in technical leadership; strong CI/CD, IaC, Docker/Kubernetes; monitoring/observability; client-facing skills.
Jenkins, GitLab CI, GitHub Actions, Ansible, Terraform, Puppet, Docker, Kubernetes, Prometheus, Grafana, ELK, Python, Go
1mo
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Staff Software Engineer
United States or Canada
$194k-$285k/yr RemoteFull Time
DoorDash
DoorDashNASDAQ: DASH: On-demand delivery platform connecting consumers with local merchants.
8+ YOE8+ years as a software engineer; expert in distributed systems, microservices, internal platforms; strong Python; AWS and Terraform; leads technical initiatives; mentors engineers.
Python, AWS, Terraform, APIs, Microservices, Containers
2mo
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Senior Analytics Engineer, Tech Lead
Minneapolis, Minnesota, United States
$99k-$173k/yr HybridFull Time
Datasite
Datasite: SaaS platform for mergers and acquisitions transaction management.
5+ YOE5+ years in analytics engineering with expert SQL, Python, Airflow, DBT, Snowflake; data modeling; data governance; mentorship.
Snowflake, DBT, Airflow, Hackolade, Python, SQL
5d
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Technical Lead, Digital Generalist
United States or Canada
$140k-$175k/yr RemoteFull Time
Left Field Labs
Left Field Labs: Creative technology agency building digital products and immersive experiences.
6+ YOEAdvanced JavaScript, HTML5, CSS3, Python, TypeScript; 6+ years in web apps; experience with React/Preact, Angular, Vue.js; Python/Node; REST; Git; cloud platforms; client interaction; project leadership.
JavaScript, HTML5, CSS3, Python, TypeScript, React, Preact, Angular, Vue.js, Node, REST, Git, GCP, GAE, Firebase, AWS, Protobufs, PubSub
2w
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Lead .NET Architect (Technology & AI Labs)
United States
RemoteFull Time
Embrace Software Inc.
Embrace Software Inc.: Acquires and scales niche vertical-market software businesses.
7+ YOE8+ years of software development; 2+ years in lead architect role; strong .NET/C# and SQL Server; experience building scalable distributed systems.
NoSQL data systems, Microsoft SQL Server, MongoDB, Windows Azure Platform, TypeScript, HTML, CSS, ASP.NET, GitHub, Data processing, API, Data architecture, RabbitMQ, Azure Service, Redis, System design, Test-driven development, Unit testing, Integration testing, NHibernate, Dapper, Release management, Artificial intelligence, Machine learning, Python programming
5d
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Lead Electrical Engineer 1 - Nuclear
United States
$118k-$180k/yr RemoteFull Time
Sargent & Lundy
Sargent & Lundy: Engineering and consulting services for the power industry.
10+ YOE3+ MgmtLead group on electrical engineering projects; 10+ years nuclear plant design; 3+ years leading a design team; BSEE ABET; PE preferred; MS Office; U.S. work authorization required.
Python, MATLAB, Excel, MS Office
1mo
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Software Engineer Manager (Remote)
United States
RemoteFull Time
The Home Depot
The Home DepotNYSE: HD: Retailer of home improvement products, building materials, and tools.
5+ YOELead software engineering team; 5+ years experience; strong Java and scripting; Python; SQL; modern web frameworks; vendor management; mentoring.
Java, Python, SQL, Spring MVC, Node.js, Ruby on Rails, React, Selenium, Logging and monitoring tools
1mo
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Staff Engineer I ( AI ‑ Native Tech Lead )
United States
$122k-$155k/yr RemoteFull Time
Cotiviti
Cotiviti: Provides data analytics and payment integrity solutions for healthcare.
8+ YOE8+ years of software engineering with leadership; strong backend/full-stack; scalable architectures; AI-assisted development tools; Java/C#/Python; SQL databases; excellent communication.
Java, C#, Python, SQL, MSSQL, Oracle, APIs

HiringCafe market data

Lead Python Developer Jobs market signals in Minnesota, United States

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
340+
Hiring companies
220+
Fresh sample
48% new in 30d
Salary visibility
82% show pay

Companies appearing in this market

AllstateCotivitiMercury InsuranceMedicaOpenTextWestern National Insurance GroupAcuityMDAd Hoc

Work location mix in visible results

Remote: 42Hybrid: 7Onsite: 1