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Lead Python Developer Jobs in Nebraska, United States

260+ lead python developer jobs from 190+ companies hiring in Nebraska, United States.

265 jobs- Nebraska
1mo
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Lead AI & Data Infrastructure Engineer
United States
$140k-$175k/yr RemoteFull Time
Matium
Matium: Digital marketplace for industrial raw material trading.
6+ YOE6+ years in data engineering, ML or applied AI; proficient in Python, SQL, data stack; experience deploying ML models; familiarity with recommender systems/marketplace algorithms; distributed data systems; scalable data pipelines; startup environment.
Python, SQL, Cloud platforms, Data pipelines, Machine learning, Big data technologies
4w
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Software Engineer, Growth
North America
$90k-$230k/yr RemoteFull Time
Monarch Money
Monarch Money: A subscription-based platform for personal budgeting and wealth management.
5+ YOE5+ years software engineering; Python, TypeScript, React; lead complex projects; remote collaboration.
Python, TypeScript, React, A/B testing, Analytics
3w
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Senior Migration Lead - Application
United States
RemoteFull Time
Quantiphi
Quantiphi: Provides applied AI research and data engineering services.
8+ YOEExperience leading application migration and modernization to AWS; strong full-stack development; CI/CD; AWS knowledge; 8+ years.
AWS, Java, C#, Node.js, Python, TypeScript, React, Angular, REST, Git, CI/CD
1w
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Lead Transport Network Engineer
Omaha, Nebraska, United States
OnsiteFull Time
Great Plains Communications
Great Plains Communications: Provides fiber internet, voice, and video services in the Midwest.
5+ YOE5+ years in large-scale routing and optical networks; expertise in SR-MPLS, BGP, OSPF/ISIS, DWDM; experience with Cisco and Ciena gear; network turn-ups; mentoring others.
Cisco, Ciena, BGP, OSPF/ISIS, DWDM, SR-MPLS, Python, Ansible
2w
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Lead Systems HPC Engineer
United States
$170k-$300k/yr RemoteFull Time
Nebius
NebiusNasdaq: NBIS: Builds cloud infrastructure and software for artificial intelligence development.
5+ YOE5+ years system-level software, 3+ years Linux, HPC, perf optimization, low-level programming.
Linux, KVM, QEMU, MPI, NCCL, InfiniBand, RoCE, PCIe, C/C++, Go, Python
2mo
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Technical Lead - Product Engineering
United States
RemoteFull Time
OpenLoop
OpenLoop: Provides white-label infrastructure and clinical support for virtual care.
8+ YOE8+ years software engineering; 2+ years leading projects; experience building operational products; AI systems in production; Proficient in Go, Python, or TypeScript; distributed systems; containerized deployments.
Go, Python, TypeScript, Docker, Kubernetes, Cloud Run, Pub/Sub, BigQuery, LangFuse, FHIR, HL7
2mo
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Principal Software Engineer, ChemDraw (C++, Web Development, TypeScript) - Remote US
United States
$142k-$180k/yr RemoteFull Time
Revvity
RevvityNYSE: RVTY: Sells diagnostic instruments and reagents for health research.
5+ YOE5+ years software development experience; strong C/C++, C#, Python desktop and 4+ years web development; prior technical lead/mentoring experience; knowledge of Windows/Mac/Linux development; UI/UX and Cheminformatics/Bioinformatics familiarity.
TypeScript, C++, C, Python, JavaScript, HTML, CSS, VS Code
3w
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Principal Software Engineer - Integration
United States
$190k-$260k/yr RemoteFull Time
Stellar Cyber
Stellar Cyber: Unified platform for automated cyber threat detection and response.
8+ YOEBachelor’s or Master’s in CS/Engineering; 8+ years backend software development; 3+ years in staff-level/tech lead; proficient in Python, Go, or Java; strong API, microservices, distributed systems; mentoring and strong communication.
Python, Go, Java, Kafka, RabbitMQ, Celery, Airflow, REST, GraphQL, OAuth, API Keys, Rate Limiting, Kubernetes, Helm, AWS, Azure, GCP, LLM APIs, MCP
2mo
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Staff Engineer - Technical Lead
San Francisco or United States
$120k-$150k/yr RemoteFull Time
Arine
Arine: Platform for optimizing medication therapy and improving healthcare outcomes.
10+ YOE10+ years in backend software and systems; strong Python and infrastructure expertise; leadership in technical delivery; healthcare data security and privacy awareness.
Python, AWS, Serverless, CloudFormation, CI/CD, Security best practices
1mo
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Staff Software Engineer - Tech Lead
United States or Canada
RemoteFull Time
Cerby
Cerby: Secures nonstandard applications that lack modern identity standards.
6+ YOE6+ years software engineering; strong system design; leadership experience; product-led mindset; able to balance short-term delivery with long-term scalability.
Python, Go, AWS, OIDC, SAML, SCIM, JWT, OpenTelemetry, Datadog
2mo
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Lead Identity Engineer (Entra ID & Okta)
United States
RemoteFull Time
By Light
By Light: IT and cybersecurity services for federal and defense agencies.
5+ YOESenior-level expertise in Microsoft Entra ID and Okta; strong SSO, MFA, lifecycle, federation experience; proven project leadership and cross-functional coordination; strong communication.
Microsoft Entra ID, Okta, SAML, OIDC, OAuth2, SCIM, Graph API, PowerShell, Python
1mo
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QA Engineer Lead (fixed-term contract)
United States
RemoteContract
Sertis
Sertis: Provides bespoke AI and data solutions for enterprise transformation.
4+ YOE4+ years in QA, test automation, or backend testing with Java; design and scale automation; API testing; CI/CD integration; microservices; production-ready testing.
Selenium, Playwright, Cypress, Postman, RestAssured, Java, JavaScript, Python, CI/CD, JMeter, Docker, Kubernetes, Observability tools
5d
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Software Engineer
Boston or United States
$108k-$192k/yr RemoteFull Time
AcuityMD
AcuityMD: Commercial intelligence platform for the medical technology industry.
1+ YOEBachelor's degree in CS/Software Eng or related field plus 1 year of experience; skills include JavaScript, TypeScript, React, Node.js, Python, Mongo, data analytics, UX analytics, and leading projects.
JavaScript, TypeScript, React, Node.js, Python, MongoDB, Data Analytics Tools, UX Analytics
2mo
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Tech Lead, Data Engineering
United States
$165k-$175k/yr RemoteFull Time
Vida Health
Vida Health: Virtual care platform treating physical and mental health conditions.
6+ YOE2+ MgmtLead backend engineering; 6+ years; Python (FastAPI); PostgreSQL; API design; architecture; 2+ years leadership; remote work eligible.
Python, FastAPI, PostgreSQL
2mo
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Lead Site Reliability Engineer (51136)
United States
$125k-$206k/yr RemoteFull Time
OpenText
OpenTextNASDAQ: OTEX: Develops enterprise software for information management and digital transformation.
SRE with Kubernetes, AWS, Terraform, Helm; CI/CD; Linux/Windows; monitoring; scripting; cloud security; on-call experience.
Kubernetes, AWS, Helm, Terraform, Prometheus, Grafana, ELK, Python, Bash, Linux, Windows
2w
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Lead ML/AI Engineer (US)
United States
$175k-$215k/yr RemoteFull Time
Penguin Solutions
Penguin SolutionsNASDAQ: PENG: Provides high-performance AI and edge computing infrastructure solutions.
7+ YOE2+ Mgmt7+ years in software/DevOps/ML; 2+ years in technical leadership; strong CI/CD, IaC, Docker/Kubernetes; monitoring/observability; client-facing skills.
Jenkins, GitLab CI, GitHub Actions, Ansible, Terraform, Puppet, Docker, Kubernetes, Prometheus, Grafana, ELK, Python, Go
2mo
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Sr Software Engineer
Omaha or Norcross
HybridFull Time
ACI Worldwide
ACI WorldwideNASDAQ: ACIW: Provides software for global real-time electronic payments.
5+ YOE5-8 years software development; lead projects; mentor engineers; payments/regulated industry experience preferred.
Java, Python, J2EE, Spring Boot, REST API, Postman, Oracle, PostgreSQL, Jenkins, Azure Pipelines, Docker, Kubernetes, AWS, Azure DevOps, Confluence, Claude, Microsoft Copilot
1mo
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Staff Software Engineer
United States or Canada
$194k-$285k/yr RemoteFull Time
DoorDash
DoorDashNASDAQ: DASH: On-demand delivery platform connecting consumers with local merchants.
8+ YOE8+ years as a software engineer; expert in distributed systems, microservices, internal platforms; strong Python; AWS and Terraform; leads technical initiatives; mentors engineers.
Python, AWS, Terraform, APIs, Microservices, Containers
5d
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Technical Lead, Digital Generalist
United States or Canada
$140k-$175k/yr RemoteFull Time
Left Field Labs
Left Field Labs: Creative technology agency building digital products and immersive experiences.
6+ YOEAdvanced JavaScript, HTML5, CSS3, Python, TypeScript; 6+ years in web apps; experience with React/Preact, Angular, Vue.js; Python/Node; REST; Git; cloud platforms; client interaction; project leadership.
JavaScript, HTML5, CSS3, Python, TypeScript, React, Preact, Angular, Vue.js, Node, REST, Git, GCP, GAE, Firebase, AWS, Protobufs, PubSub
2w
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Lead .NET Architect (Technology & AI Labs)
United States
RemoteFull Time
Embrace Software Inc.
Embrace Software Inc.: Acquires and scales niche vertical-market software businesses.
7+ YOE8+ years of software development; 2+ years in lead architect role; strong .NET/C# and SQL Server; experience building scalable distributed systems.
NoSQL data systems, Microsoft SQL Server, MongoDB, Windows Azure Platform, TypeScript, HTML, CSS, ASP.NET, GitHub, Data processing, API, Data architecture, RabbitMQ, Azure Service, Redis, System design, Test-driven development, Unit testing, Integration testing, NHibernate, Dapper, Release management, Artificial intelligence, Machine learning, Python programming
5d
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Lead Electrical Engineer 1 - Nuclear
United States
$118k-$180k/yr RemoteFull Time
Sargent & Lundy
Sargent & Lundy: Engineering and consulting services for the power industry.
10+ YOE3+ MgmtLead group on electrical engineering projects; 10+ years nuclear plant design; 3+ years leading a design team; BSEE ABET; PE preferred; MS Office; U.S. work authorization required.
Python, MATLAB, Excel, MS Office
1mo
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Software Engineer Manager (Remote)
United States
RemoteFull Time
The Home Depot
The Home DepotNYSE: HD: Retailer of home improvement products, building materials, and tools.
5+ YOELead software engineering team; 5+ years experience; strong Java and scripting; Python; SQL; modern web frameworks; vendor management; mentoring.
Java, Python, SQL, Spring MVC, Node.js, Ruby on Rails, React, Selenium, Logging and monitoring tools
1w
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Staff Software Engineer, Attack
United States
$220k-$275k/yr RemoteFull Time
Horizon3.ai
Horizon3.ai: Autonomous penetration testing platform for continuous security assessment.
Lead/Staff level backend engineer; production code in Go, Rust, Python; strong leadership and mentoring; EDR telemetry and ML/AI research interest.
Go, Rust, Python
1mo
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Staff Engineer I ( AI ‑ Native Tech Lead )
United States
$122k-$155k/yr RemoteFull Time
Cotiviti
Cotiviti: Provides data analytics and payment integrity solutions for healthcare.
8+ YOE8+ years of software engineering with leadership; strong backend/full-stack; scalable architectures; AI-assisted development tools; Java/C#/Python; SQL databases; excellent communication.
Java, C#, Python, SQL, MSSQL, Oracle, APIs
2w
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Lead Cloud Systems Engineer (Microsoft 365, AWS, Collaboration Tools)
United States
$157k-$181k/yr RemoteFull Time
U.S. Financial Technology
U.S. Financial Technology: Operates a cloud platform for mortgage-backed securities administration.
7+ YOE3+ Mgmt7+ years in Microsoft 365 admin and collaboration tech; 3+ years in a lead role; experience with CA policies, Entra ID, Purview, Intune, AD, Teams Room; audits/compliance; US work authorization.
Microsoft 365, AWS, Intune, Entra ID, Purview, Active Directory, Microsoft Teams Room, Copilot, Security Copilot, ChatGPT, GPO, SharePoint, Exchange Online, PowerShell, Python, AWS EC2, VPC, RDS, S3
1mo
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Senior Software Engineer
United States
$135k-$216k/yr RemoteFull Time
Peraton
Peraton: National security and mission-critical government technology services provider.
12+ YOELead software development for satellite ground system software; manage team; ensure SDLC compliance; integrate COTS components; coordinate with systems and cybersecurity teams.
Java, C++, Python, PowerShell, Perl, Bash, Groovy, XML, Git, Gradle, Ant, Jenkins, CI/CD, VHDL, Linux, JIRA, Confluence
4w
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Staff Software Engineer (L4) Data Platform
United States
$171k-$214k/yr RemoteFull Time
Twilio
TwilioNYSE: TWLO: Cloud communications platform for programmable messaging, voice, and email.
8+ YOE8+ years in software development; Bachelor's or Master's in CS/Engineering; experience leading data projects and distributed systems; proficiency in Python/Java/Scala; big data tech (Hadoop/Spark/Kafka); AWS; Data Lakehouse (Hudi/Iceberg/Delta); strong leadership and communication.
Hadoop, Spark, Kafka, AWS, Python, Java, Scala, Hudi, Iceberg, Delta
2w
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Lead Product Manager, Developer Experience (platform-to-product)
United States or United States
$161k-$183k/yr RemoteFull Time
WEX
WEXNYSE: WEX: Provides global payment processing and business information management services.
7+ YOE7+ years in technical product management or engineering; strong data infra/devops experience; SQL and Python or Spark; experience building developer tools and data platforms; able to navigate ambiguity and drive cross-functional initiatives.
SQL, Python, Spark, Airflow, Dagster, Snowflake, Databricks, Kubernetes
1d
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Lead Principal Engineer - Data Centre, Cloud & Network Operations
United States
$48-$65/hr RemoteContract
Gruve
Gruve: Provides enterprise AI infrastructure and autonomous software agents.
8+ YOE8+ years in enterprise Network/Security engineering; 24x7 global operations; hands-on networking, firewalls, VPNs, cloud; incident leadership; contract role.
Terraform, Ansible, CloudFormation, Python
1mo
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Technical Lead Engineer – Medicaid Enterprise Data Warehouse (MEDW)
United States
$110k-$140k/yr RemoteFull Time
Conduent
ConduentNASDAQ: CNDT: Provides digital business solutions and business process services globally.
7+ YOE3+ Mgmt7+ years in data warehousing/enterprise data systems; 3+ years in technical leadership; healthcare/Medicaid domain experience; strong SQL, data modeling, and ETL/ELT skills; familiarity with CMS/Medicaid data standards.
SQL, ETL/ELT, Informatica, Tableau, SAS, Azure Synapse, SQL Server, Oracle, PowerShell, Python, Airflow, SSIS
1mo
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Staff Software Engineer
United States
RemoteFull Time
Playlist
Playlist: Software and marketplace platform for the wellness industry.
10+ YOE10+ years of software engineering; experience leading cross-team architecture; production microservices; AWS and containerization; monitoring/logging; SQL relational modeling; multi-language backend (ASP.NET, Python, C#, Ruby); frontend collaboration (Next.js, React).
AWS, EKS, EC2, ElastiCache, SNS, SQS, New Relic, Kibana, SQL, Relational data modeling, .NET Core, ASP.NET, C#, Python, Next.js, React, Ruby
3w
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Software Engineer (SWE & Staff SWE Openings)
United States
$85k-$185k/yr RemoteFull Time
Bold Penguin
Bold Penguin: Provides digital platforms for commercial insurance quoting and distribution.
3+ YOE3+ years software development experience, with Ruby on Rails; strong cloud, security, and scalability focus; proven ability to mentor and lead while contributing as an individual.
Ruby on Rails, Cloud, DevOps, CI/CD, Site Reliability Engineering, Python
3w
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Lead Mission Engineer (Full Stack)
United States
$157k-$224k/yr RemoteFull Time
Systems & Technology Research
Systems & Technology Research: Develops advanced technology for national security and defense applications.
7+ YOEBS in Computer Science or related field; 7+ years DoD/IC software deployment; ability to obtain Top Secret/SCI; strong frontend/backend skills; experience leading teams and customer collaboration.
React, TypeScript, Python
2mo
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Senior Full-stack Engineer (LatAm)
United States
RemoteFull Time
SecurityScorecard
SecurityScorecard: Providing security ratings and continuous risk monitoring for organizations.
5+ YOE5+ years in full-stack development; strong React/Node.js; experience with PostgreSQL and distributed systems; CI/CD, AWS; ability to lead projects and collaborate with product teams.
Node.js, Typescript, Python, React, PostgreSQL, ClickHouse, CockroachDB, Kafka, Docker, Jenkins, Terraform, AWS
2mo
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Staff Software Engineer, Fintech & Earnings
Canada or United States
$173k-$208k/yr RemoteFull Time
Super.com
Super.com: An all-in-one savings app for travel and financial services.
10+ YOE10+ years in software development; senior/lead experience; full-stack with frontend, servers, and databases; cross-functional collaboration; strong communication; AI fluency; startup mindset.
Node.js, Python, React, PostgreSQL, Redis, Snowflake, GitLab, AWS, Kubernetes, RDS, Datadog, Amplitude, Hotjar, LogRocket, Material-UI
1mo
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Senior Full Stack Developer (React)
New Hyde Park or Moline or Hartford or Framingham or West Palm Beach or Norcross or Chicago or Milwaukee or Baltimore or Piscataway or United States
$125k-$150k/yr RemoteFull Time
Parts Authority
Parts Authority: Distributes automotive and truck replacement parts to the aftermarket industry.
5+ YOE5+ years professional experience building production web apps; 2+ years in senior/lead roles; strong Python and React/TypeScript; AI/ML integration; Kafka/event-driven architectures; PostgreSQL/Redis; Kubernetes/DevOps; AS400 integration experience preferred
Python, FastAPI, SQLAlchemy, Pydantic, React, TypeScript, Tailwind, Redis, PostgreSQL, Kafka, Databricks, MLflow, Airflow, Docker, Kubernetes, GitHub Actions, ODBC, Data Queues, RBAC, OAuth
2w
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AI Application Developer
United States
$150k-$205k/yr RemoteFull Time
Eversheds Sutherland
Eversheds Sutherland: Global law firm providing legal and business advisory services.
5+ YOE5+ years in software or AI development; 2+ years in technical lead/architect role; strong experience with LLMs, RAG, Azure AI Foundry, Power Platform, SQL, Python/JS, and DevOps.
Azure AI Foundry, LangChain, Semantic Kernel, Pinecone, Weaviate, Power Platform, Power Automate, Power Apps, AI Builder, SQL, Python, JavaScript, TypeScript, Git, Azure DevOps, GitHub Actions, iManage, SharePoint, Teams
1mo
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AI Engineer
United States or North America
$130k-$140k/yr RemoteFull Time
Panopto
Panopto: Video management platform for educational and corporate learning.
Experienced AI engineer with production‑oriented AI/ML skills, strong software engineering fundamentals, and ability to lead AI initiatives.
Python, LLM tooling, API design, Cloud services
2mo
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Senior SOC Engineer (Security Operations Technical Lead) - Remote (USA)
United States
RemoteFull Time
Echelon Risk + Cyber
Echelon Risk + Cyber: Provides expert-led cybersecurity consulting and managed security services.
7+ YOESenior SOC Engineer with MSSP experience, hands-on security engineering, leading SOC processes, detection engineering, incident response, and client engagement.
EDR, XDR, MDR, CrowdStrike, SentinelOne, Blackpoint, Microsoft Defender for Endpoint, Cortex XDR, Microsoft 365 security, SIEM, SOAR, email security, vulnerability scanners, NSM tools, AWS, Azure, GCP, M365, PowerShell, Python, KQL, SPL, Elastic DSL, AQL
2mo
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Staff Software Engineer, Ads Measurement Products
San Francisco or United States
$177k-$365k/yr RemoteFull Time
Pinterest
PinterestNYSE: PINS: Operates a visual discovery platform for finding creative inspiration.
8+ YOEBS+ in Computer Science or related field; 8+ years in software engineering; strong data-pipeline and distributed-systems experience; proficiency in Java/Scala/Kotlin or Python plus SQL; experience with AI enablement and AdTech/measurement products; ability to lead cross-functional initiatives.
Java, Scala, Kotlin, Python, SQL

HiringCafe market data

Lead Python Developer Jobs market signals in Nebraska, United States

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
260+
Hiring companies
190+
Fresh sample
46% new in 30d
Salary visibility
69% show pay

Companies appearing in this market

CotivitiACI WorldwideGreat Plains CommunicationsHorizon3.aiOpenTextSuper.comAcuityMDArine

Work location mix in visible results

Remote: 44Hybrid: 2Onsite: 2